Effects of Enterococcus faecium, mannan oligosaccharide, benzoic acid and their mixture on growth performance, intestinal microbiota, intestinal morphology and blood lymphocyte subpopulations of fattening pigs

Animal Feed Science and Technology

Volumn 220, Issue , 2016, Pages 159-167

  Giannenas, I ^a   Doukas, D ^b   Karamoutsios, A ^c   Tzora, A ^c   Bonos, E ^a   Skoufos, I ^c   Tsinas, A ^c   Christaki, E ^a   Tontis, D ^b   Florou Paneri, P ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b UNIVERSITY OF THESSALY   (Greece)

^c Epirus Institute of Technology Arta   (Greece)

Author keywords

Benzoic acid; Enterococcus faecium; Fattening pigs; Intestinal microbiota; Lymphocyte subpopulation; Mannan oligosaccharides

Indexed keywords

EID: 84995467594     PISSN: 03778401     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anifeedsci.2016.08.003     Document Type: Article

References (42)

1. Adewole, D.I., Kim, I.H., Nyachoti, C.M., Gut health of pigs: a review of challenge models and response criteria with a critical analysis of the effectiveness of selected feed additives—review. Asian Australas. J. Anim. Sci. 29 (2016), 909–924.
2. Barrow, G.I., Feltham, R.K.A., Manual for the Identification of Medical Bacteria. 1993, Cambridge University Press, Cambridge.
3. Bonos, E., Christaki, E., Abrahim, A., Soultos, N., Florou-Paneri, P., The influence of mannan oligosaccharides, acidifiers and their combination on caecal microflora of Japanese quail (Coturnix japonica). Anaerobe 17 (2011), 436–439.
4. Broom, L.J., Miller, H.M., Kerr, K.G., Knapp, J.S., Effects of zinc oxide and Enterococcus faecium SF68 dietary supplementation on the performance, intestinal microbiota and immune status of weaned piglets. Res. Vet. Sci. 80 (2006), 45–54.
5. Buhler, K., Bucher, B., Wenk, C., Broz, J., Influence of benzoic acid in high fibre diets on nutrient digestibility and VFA production in growing/finishing pigs. Arch. Anim. Nutr. 63 (2009), 127–136.
6. Buhler, K., Liesegang, A., Bucher, B., Wenk, C., Broz, J., Influence of benzoic acid and phytase in low-phosphorus diets on bone characteristics in growing-finishing pigs. J. Anim. Sci. 88 (2010), 3363–3371.
7. Devi, S.M., Lee, K.Y., Kim, I.H., Analysis of the effect of dietary protected organic acid blend on lactating sows and their piglets. Rev. Bras. Zootec. 45 (2016), 39–47.
8. Devriese, L.A., Pot, B., Collins, M.D., Phenotypic identification of the genus Enterococcus and differentiation of phylogenetically distinct enterococcal species and species groups. J. Appl. Bacteriol. 75 (1993), 399–408.
9. Diao, H., Zheng, P., Yu, B., He, J., Mao, X.B., Yu, J., Chen, D.W., Effects of dietary supplementation with benzoic acid on intestinal morphological structure and microflora in weaned piglets. Livest. Sci. 167 (2014), 249–256.
10. ®) on the performance and jejunal digestive physiology in young pigs. J. Anim. Sci. Biotechnol. 7 (2016), 1–7.
11. Dierick, N.A., Michiels, J., Van, N.C., Effect of medium chain fatty acids and benzoic acid, as alternatives for antibiotics, on growth and some gut parameters in piglets. Commun. Agric. Appl. Biol. Sci. 69 (2004), 187–190.
12. Fessele, C., Lindhorst, T.K., Effect of aminophenyl and aminothiahexyl α-d-glycosides of the manno- gluco-, and galacto-series on type 1 fimbriae-mediated adhesion of Escherichia coli. Biology (Basel) 2 (2013), 1135–1149.
13. Fuller, R., Probiotics in man and animals. J. Appl. Bacteriol. 66 (1989), 365–378.
14. Giannenas, I., Tsalie, E., Triantafillou, E., Henikl, S., Teichmann, K., Mohnl, M., Tontis, D., Assessment of probiotics supplementation via feed or water on the growth performance, intestinal morphology and microflora of chicken after experimental infection with Eimeria acervulina, Eimeria maxima and Eimeria tenella. Avian Pathol. 23 (2014), 73–81.
15. Giannenas, I.A., Papaneophytou, C.P., Tsalie, E., Triantafillou, E., Tontis, D., Kontopidis, G.A., The effects of benzoic acid and essential oil compounds in combination with protease on the performance of chickens. J. Anim. Feed Sci. 23 (2014), 73–81.
16. ®) on the zootechnical performance, the gastrointestinal microflora and the ileal digestibility of the young pig. Livest. Sci. 108 (2007), 218–221.
17. Heo, J.M., Opapeju, F.O., Pluske, J.R., Kim, J.C., Hampson, D.J., Nyachoti, C.M., Gastrointestinal health and function in weaned pigs: a review of feeding strategies to control post-weaning diarrhoea without using in-feed antimicrobial compounds. J. Anim. Physiol. Anim. Nutr. 97 (2013), 207–237.
18. Kik, M.J., Huisman, J., Van Der Poel, A.F., Mouwen, J.M., Pathologic changes of the small intestinal mucosa of pigs after feeding Phaseolus vulgaris beans. Vet. Pathol. 27 (1990), 329–334.
19. Kluge, H., Broz, J., Eder, K., Effect of benzoic acid on growth performance, nutrient digestibility, nitrogen balance, gastrointestinal microflora and parameters of microbial metabolism in piglets. J. Anim. Physiol. Anim. Nutr. 90 (2006), 316–324.
20. Knarreborg, A., Miquel, N., Granli, T., Jensen, B.B., Establishment and application of an in vitro methodology to study the effects of organic acids on coliform and lactic acid bacteria in the proximal part of the gastrointestinal tract of piglets. Anim. Feed Sci. Technol. 99 (2002), 131–140.
21. Kolling, G., Wu, M., Guerrant, R.L., Enteric pathogens through life stages. Front. Cell Infect. Microbiol., 2012, 1–8.
22. Maeng, W.J., Kin, C.W., Shin, H.T., Effect of feeding lactic acid bacteria concentrate (LBC, Streptococcus faecium Cernelle 68) on growth rate and prevention of scouring in piglet. Korean J. Anim. Sci. 31 (1989), 318–323.
23. Maribo, H., Olsen, L.E., Mishler, D.R., Jensen, B.B., Miquel, N., 2000. Products for weaners: Benzoic acid or the combination of lactic acid and formic acid, In: Production, C.T.N.C.f.P. (Ed.), Report No: 490, Copenhagen: The National Committee for Pig Production, Copenhagen, pp. 1–16.
24. Martin, L., Pieper, R., Kroger, S., Goodarzi Boroojeni, F., Vahjen, W., Neumann, K., Van Kessel, A.G., Zentek, J., Influence of age and Enterococcus faecium NCIMB 10415 on development of small intestinal digestive physiology in piglets. Anim. Feed Sci. Technol. 175 (2012), 65–75.
25. Monsan, P., Bozonnet, S., Albenne, C., Jouela, G., Willemot, R.M., Remaud-Simeon, M., Homopolysaccharides from lactic acid bacteria. Int. Dairy J. 11 (2001), 675–685.
26. Mountzouris, K.C., Assessment of the efficacy of probiotics, prebiotics and synbiotics in swine nutrition: a review. Food Sci. Technol. Bull. 3 (2006), 51–71.
27. NRC, Guide for the Care and Use of Laboratory Animals. 1996, National Academy Press, Washington, DC.
28. NRC, Nutrient Requirements of Swine: Eleventh Revised Edition. 2012, National Academy Press, Washington D.C, USA.
29. Pluske, J., Williams, I., Aherne, F., Maintenance of villous height and crypt depth in piglets by providing continuous nutrition after weaning. Anim. Sci. 62 (1996), 131–144.
30. Pollman, D.S., Danielson, D.M., Peo, E.R. Jr., Effects of microbial feed additives on performance of starter and growing-finishing pigs. J. Anim. Sci. 51 (1980), 577–581.
31. Potten, C.S., Stem cells in the gastrointestinal epithelium: numbers, characteristics and death. Philos. Trans. R. Soc. B Biol. Sci. 353 (1998), 821–830.
32. Roberfroid, M., Prebiotics: the concept revisited. J. Nutr. 137 (2007), 830S–837S.
33. Scharek, L., Guth, J., Reiter, K., Weyrauch, K.D., Taras, D., Schwerk, P., Schierack, P., Schmidt, M.F., Wieler, L.H., Tedin, K., Influence of a probiotic Enterococcus faecium strain on development of the immune system of sows and piglets. Vet. Immunol. Immunopathol. 105 (2005), 151–161.
34. Subramaniam, M.D., Kim, I.H., Clays as dietary supplements for swine: a review. J. Anim. Sci. Biotechnol., 6, 2015, 38.
35. Torrallardona, D., Badiola, D., Broz, J., Effects of benzoic acid on performance and ecology of gastrointestinal microbiota in weaned piglets. Livest. Sci. 108 (2007), 210–213.
36. Van den Bogaard, A.E., Stobberingh, E.E., Epidemiology of resistance to antibiotics: links between animals and humans. Int. J. Antimicrob. Agents 14 (2000), 327–335.
37. Verstegen, M.W.A., Williams, B.A., Alternatives to the use of antibiotics as growth promoters for monogastric animals. Anim. Biotechnol. 13 (2002), 113–127.
38. Waters, W.R., Harkins, K.R., Wannemuehler, M.J., Five-color flow cytometric analysis of swine lymphocytes for detection of proliferation, apoptosis, viability, and phenotype. Cytometry 48 (2002), 146–152.
39. Yang, H., Parkhouse, R.M., Phenotypic classification of porcine lymphocyte subpopulations in blood and lymphoid tissues. Immunology 89 (1996), 76–83.
40. Zhang, T.T., Zhou, Y.F., Zou, Y., Hu, X.M., Zheng, L.F., Wei, H.K., Giannenas, I., Jin, L.Z., Peng, J., Jiang, S.W., Effects of dietary oregano essential oil supplementation on the stress response, antioxidative capacity, and HSPs mRNA expression of transported pigs. Livest. Sci. 180 (2015), 143–149.
41. Zhang, Z.F., Rolando, A.V., Kim, I.H., Effects of benzoic acid, essential oils and Enterococcus faecium SF68 on growth performance, nutrient digestibility, blood profiles, faecal microbiota and faecal noxious gas emission in weanling pigs. J. Appl. Anim. Res. 44 (2016), 173–179.
42. Zitnan, R., Voigt, J., Kuhla, S., Wegner, J., Chudy, A., Schonhusen, U., Bma, M., Zupcanova, M., Hagemeister, H., Morphology of small intestinal mucosa and intestinal weight change with metabolic type of cattle. Vet. Med. (Praha) 53 (2008), 525–532.