메뉴 건너뛰기




Volumn 30, Issue 6, 2016, Pages 587-598

Evaluation and Treatment of Endoplasmic Reticulum (ER) Stress in Right Ventricular Dysfunction during Monocrotaline-Induced Rat Pulmonary Arterial Hypertension

Author keywords

Apoptosis; Endoplasmic reticulum (ER) stress; Inflammation; Pulmonary artery hypertension; Right ventricular dysfunction

Indexed keywords

4 PHENYLBUTYRIC ACID; ACTIVATING TRANSCRIPTION FACTOR 6; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; ANTIHYPERTENSIVE AGENT; BIOLOGICAL MARKER; GELATINASE A; GELATINASE B; GLUCOSE REGULATED PROTEIN 78; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INTERLEUKIN 6; MESSENGER RNA; PROTEIN IRE1; PROTEIN KINASE RNA LIKE ENDOPLASMIC RETICULUM KINASE; REGULATOR OF CALCINEURIN 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; 4-PHENYLBUTYRIC ACID; ARYLBUTYRIC ACID DERIVATIVE; ATF6 PROTEIN, RAT; BRAIN NATRIURETIC PEPTIDE; DDIT3 PROTEIN, RAT; ERN2 PROTEIN, RAT; HEAT SHOCK PROTEIN; HSPA5 PROTEIN, RAT; MEMBRANE PROTEIN; MONOCROTALINE; PEPTIDE FRAGMENT; PERK KINASE; PRO-BRAIN NATRIURETIC PEPTIDE (1-76); PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE;

EID: 84995466607     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-016-6702-1     Document Type: Article
Times cited : (38)

References (39)
  • 1
    • 64849109410 scopus 로고    scopus 로고
    • ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation task force on expert consensus documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association
    • PID: 19389575
    • McLaughlin VV, Archer SL, Badesch DB, et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation task force on expert consensus documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association. J Am Coll Cardiol. 2009;53:1573–619.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1573-1619
    • McLaughlin, V.V.1    Archer, S.L.2    Badesch, D.B.3
  • 2
    • 57749115658 scopus 로고    scopus 로고
    • Therapeutic targets in pulmonary arterial hypertension
    • COI: 1:CAS:528:DC%2BD1cXhsFagtrrK, PID: 19010350
    • Rhodes CJ, Davidson A, Gibbs JS, et al. Therapeutic targets in pulmonary arterial hypertension. Pharmacol Ther. 2009;121:69–88.
    • (2009) Pharmacol Ther , vol.121 , pp. 69-88
    • Rhodes, C.J.1    Davidson, A.2    Gibbs, J.S.3
  • 3
    • 85026335812 scopus 로고    scopus 로고
    • Is cardiac resynchronization therapy for right ventricular failure in pulmonary arterial hypertension of benefit?
    • PID: 25610593
    • Rasmussen JT, Thenappan T, Benditt DG, et al. Is cardiac resynchronization therapy for right ventricular failure in pulmonary arterial hypertension of benefit? Pulm Circ. 2014;4:552–9.
    • (2014) Pulm Circ , vol.4 , pp. 552-559
    • Rasmussen, J.T.1    Thenappan, T.2    Benditt, D.G.3
  • 4
    • 75249089553 scopus 로고    scopus 로고
    • Systematic review of trials using vasodilators in pulmonary arterial hypertension: why a new approach is needed
    • COI: 1:CAS:528:DC%2BC3cXhs1Gksbw%3D, PID: 20152223
    • Macchia A, Marchioli R, Tognoni G, et al. Systematic review of trials using vasodilators in pulmonary arterial hypertension: why a new approach is needed. Am Heart J. 2010;159:245–57.
    • (2010) Am Heart J , vol.159 , pp. 245-257
    • Macchia, A.1    Marchioli, R.2    Tognoni, G.3
  • 5
    • 84860404865 scopus 로고    scopus 로고
    • Meta-analysis of monotherapy versus combination therapy for pulmonary arterial hypertension
    • COI: 1:CAS:528:DC%2BC3MXht1yltr3O, PID: 21864815
    • Fox BD, Shimony A, Langleben D. Meta-analysis of monotherapy versus combination therapy for pulmonary arterial hypertension. Am J Cardiol. 2011;108:1177–82.
    • (2011) Am J Cardiol , vol.108 , pp. 1177-1182
    • Fox, B.D.1    Shimony, A.2    Langleben, D.3
  • 6
    • 84899834869 scopus 로고    scopus 로고
    • Comparative effectiveness and safety of drug therapy for pulmonary arterial hypertension: a systematic review and meta-analysis
    • PID: 24371842
    • Coeytaux RR, Schmit KM, Kraft BD, et al. Comparative effectiveness and safety of drug therapy for pulmonary arterial hypertension: a systematic review and meta-analysis. Chest. 2014;145:1055–63.
    • (2014) Chest , vol.145 , pp. 1055-1063
    • Coeytaux, R.R.1    Schmit, K.M.2    Kraft, B.D.3
  • 7
    • 33750560212 scopus 로고    scopus 로고
    • Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure
    • PID: 17060398
    • Voelkel NF, Quaife RA, Leinwand LA, et al. Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation. 2006;114:1883–91.
    • (2006) Circulation , vol.114 , pp. 1883-1891
    • Voelkel, N.F.1    Quaife, R.A.2    Leinwand, L.A.3
  • 8
    • 77954758530 scopus 로고    scopus 로고
    • Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era
    • PID: 20585011
    • Humbert M, Sitbon O, Chaouat A, et al. Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation. 2010;122:156–63.
    • (2010) Circulation , vol.122 , pp. 156-163
    • Humbert, M.1    Sitbon, O.2    Chaouat, A.3
  • 9
    • 82455203954 scopus 로고    scopus 로고
    • Progressive right ventricular dysfunction in patients with pulmonary arterial hypertension responding to therapy
    • PID: 22133851
    • van de Veerdonk MC, Kind T, Marcus JT, et al. Progressive right ventricular dysfunction in patients with pulmonary arterial hypertension responding to therapy. J Am Coll Cardiol. 2011;58:2511–9.
    • (2011) J Am Coll Cardiol , vol.58 , pp. 2511-2519
    • van de Veerdonk, M.C.1    Kind, T.2    Marcus, J.T.3
  • 10
    • 34548303769 scopus 로고    scopus 로고
    • Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension
    • PID: 17242010
    • van Wolferen SA, Marcus JT, Boonstra A, et al. Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension. Eur Heart J. 2007;28:1250–7.
    • (2007) Eur Heart J , vol.28 , pp. 1250-1257
    • van Wolferen, S.A.1    Marcus, J.T.2    Boonstra, A.3
  • 11
    • 67349236397 scopus 로고    scopus 로고
    • The remodeling of connexin in the hypertrophied right ventricular in pulmonary arterial hypertension and the effect of a dual ET receptor antagonist (bosentan)
    • COI: 1:CAS:528:DC%2BD1MXosFClu7s%3D, PID: 19232841
    • Tan XY, He JG. The remodeling of connexin in the hypertrophied right ventricular in pulmonary arterial hypertension and the effect of a dual ET receptor antagonist (bosentan). Pathol Res Pract. 2009;205:473–82.
    • (2009) Pathol Res Pract , vol.205 , pp. 473-482
    • Tan, X.Y.1    He, J.G.2
  • 12
    • 77957694135 scopus 로고    scopus 로고
    • Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats
    • COI: 1:CAS:528:DC%2BC3cXht1yhtrzJ, PID: 20508210
    • Bogaard HJ, Natarajan R, Mizuno S, et al. Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats. Am J Respir Crit Care Med. 2010;182:652–60.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 652-660
    • Bogaard, H.J.1    Natarajan, R.2    Mizuno, S.3
  • 13
    • 84883780549 scopus 로고    scopus 로고
    • Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling
    • PID: 22854298
    • Kojonazarov B, Sydykov A, Pullamsetti SS, et al. Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling. Int J Cardiol. 2013;167:2630–7.
    • (2013) Int J Cardiol , vol.167 , pp. 2630-2637
    • Kojonazarov, B.1    Sydykov, A.2    Pullamsetti, S.S.3
  • 14
    • 72449124776 scopus 로고    scopus 로고
    • Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure
    • PID: 19884466
    • Bogaard HJ, Natarajan R, Henderson SC, et al. Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure. Circulation. 2009;120:1951–60.
    • (2009) Circulation , vol.120 , pp. 1951-1960
    • Bogaard, H.J.1    Natarajan, R.2    Henderson, S.C.3
  • 15
    • 27144506750 scopus 로고    scopus 로고
    • Angiotensin receptor blockade and exercise capacity in adults with systemic right ventricles: a multicenter, randomized, placebo-controlled clinical trial
    • COI: 1:CAS:528:DC%2BD2MXhtV2rt7vP, PID: 16216961
    • Dore A, Houde C, Chan KL, et al. Angiotensin receptor blockade and exercise capacity in adults with systemic right ventricles: a multicenter, randomized, placebo-controlled clinical trial. Circulation. 2005;112:2411–6.
    • (2005) Circulation , vol.112 , pp. 2411-2416
    • Dore, A.1    Houde, C.2    Chan, K.L.3
  • 16
    • 84890606655 scopus 로고    scopus 로고
    • Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology
    • PID: 24355638
    • Vonk-Noordegraaf A, Haddad F, Chin KM, et al. Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology. J Am Coll Cardiol. 2013;62:D22–33.
    • (2013) J Am Coll Cardiol , vol.62 , pp. D22-D33
    • Vonk-Noordegraaf, A.1    Haddad, F.2    Chin, K.M.3
  • 17
    • 78549288890 scopus 로고    scopus 로고
    • Kim do H, et al. biology of endoplasmic reticulum stress in the heart
    • COI: 1:CAS:528:DC%2BC3cXhsVWht77K, PID: 21071716
    • Groenendyk J, Sreenivasaiah PK. Kim do H, et al. biology of endoplasmic reticulum stress in the heart. Circ Res. 2010;107:1185–97.
    • (2010) Circ Res , vol.107 , pp. 1185-1197
    • Groenendyk, J.1    Sreenivasaiah, P.K.2
  • 18
    • 78349265743 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease
    • COI: 1:CAS:528:DC%2BC3cXhtlGjsrrI, PID: 21030724
    • Minamino T, Komuro I, Kitakaze M. Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease. Circ Res. 2010;107:1071–82.
    • (2010) Circ Res , vol.107 , pp. 1071-1082
    • Minamino, T.1    Komuro, I.2    Kitakaze, M.3
  • 19
    • 77952675374 scopus 로고    scopus 로고
    • ER stress in cardiovascular disease
    • COI: 1:CAS:528:DC%2BC3cXlvVels78%3D, PID: 19913545
    • Minamino T, Kitakaze M. ER stress in cardiovascular disease. J Mol Cell Cardiol. 2010;48:1105–10.
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 1105-1110
    • Minamino, T.1    Kitakaze, M.2
  • 20
    • 84872037440 scopus 로고    scopus 로고
    • Activation of the unfolded protein response is associated with pulmonary hypertension
    • COI: 1:CAS:528:DC%2BC38XpvFyls7c%3D, PID: 22837864
    • Yeager ME, Reddy MB, Nguyen CM, et al. Activation of the unfolded protein response is associated with pulmonary hypertension. Pulm Circ. 2012;2:229–40.
    • (2012) Pulm Circ , vol.2 , pp. 229-240
    • Yeager, M.E.1    Reddy, M.B.2    Nguyen, C.M.3
  • 21
    • 84872082742 scopus 로고    scopus 로고
    • Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension
    • COI: 1:CAS:528:DC%2BC3sXjs1yqsw%3D%3D, PID: 23149668
    • Dromparis P, Paulin R, Stenson TH, et al. Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension. Circulation. 2013;127:115–25.
    • (2013) Circulation , vol.127 , pp. 115-125
    • Dromparis, P.1    Paulin, R.2    Stenson, T.H.3
  • 22
    • 84900556997 scopus 로고    scopus 로고
    • Reduction of endoplasmic reticulum stress by 4-phenylbutyric acid prevents the development of hypoxia-induced pulmonary arterial hypertension
    • COI: 1:CAS:528:DC%2BC2cXptVChs7k%3D, PID: 24610918
    • Koyama M, Furuhashi M, Ishimura S, et al. Reduction of endoplasmic reticulum stress by 4-phenylbutyric acid prevents the development of hypoxia-induced pulmonary arterial hypertension. Am J Physiol Heart Circ Physiol. 2014;306:H1314–23.
    • (2014) Am J Physiol Heart Circ Physiol , vol.306 , pp. H1314-H1323
    • Koyama, M.1    Furuhashi, M.2    Ishimura, S.3
  • 23
    • 84884253112 scopus 로고    scopus 로고
    • Experimental models of right heart failure: a window for translational research in pulmonary hypertension
    • PID: 24037635
    • Guihaire J, Bogaard HJ, Flecher E, et al. Experimental models of right heart failure: a window for translational research in pulmonary hypertension. Semin Respir Crit Care Med. 2013;34:689–99.
    • (2013) Semin Respir Crit Care Med , vol.34 , pp. 689-699
    • Guihaire, J.1    Bogaard, H.J.2    Flecher, E.3
  • 24
    • 84866129433 scopus 로고    scopus 로고
    • Nicorandil prevents right ventricular remodeling by inhibiting apoptosis and lowering pressure overload in rats with pulnary arterial hypertension
    • COI: 1:CAS:528:DC%2BC38XhtlGks7bF, PID: 22970229
    • Zuo XR, Wang Q, Cao Q, et al. Nicorandil prevents right ventricular remodeling by inhibiting apoptosis and lowering pressure overload in rats with pulnary arterial hypertension. PLoS One. 2012;7:e44485.
    • (2012) PLoS One , vol.7
    • Zuo, X.R.1    Wang, Q.2    Cao, Q.3
  • 25
    • 38549151187 scopus 로고    scopus 로고
    • Role of bradykinin, nitric oxide, and angiotensin II type 2 receptor in imidapril-induced angiogenesis
    • COI: 1:CAS:528:DC%2BD1cXmt1OjsQ%3D%3D, PID: 18086946
    • Li P, Kondo T, Numaguchi Y, et al. Role of bradykinin, nitric oxide, and angiotensin II type 2 receptor in imidapril-induced angiogenesis. Hypertension. 2008;51:252–8.
    • (2008) Hypertension , vol.51 , pp. 252-258
    • Li, P.1    Kondo, T.2    Numaguchi, Y.3
  • 26
    • 84885370944 scopus 로고    scopus 로고
    • Right ventricular myocardial performance index is decreased with severe pressure-overload cardiac hypertrophy in young rats
    • PID: 23467728
    • Ko JH, Eom GH, Cho HJ, et al. Right ventricular myocardial performance index is decreased with severe pressure-overload cardiac hypertrophy in young rats. Pediatr Cardiol. 2013;34:1556–66.
    • (2013) Pediatr Cardiol , vol.34 , pp. 1556-1566
    • Ko, J.H.1    Eom, G.H.2    Cho, H.J.3
  • 27
    • 25444458591 scopus 로고    scopus 로고
    • Preferable anesthetic conditions for echocardiographic determination of murine cardiac function
    • COI: 1:CAS:528:DC%2BD2MXhtVOqsrvM, PID: 16177543
    • Kawahara Y, Tanonaka K, Daicho T, et al. Preferable anesthetic conditions for echocardiographic determination of murine cardiac function. J Pharmacol Sci. 2005;99:95–104.
    • (2005) J Pharmacol Sci , vol.99 , pp. 95-104
    • Kawahara, Y.1    Tanonaka, K.2    Daicho, T.3
  • 28
    • 84905190172 scopus 로고    scopus 로고
    • A molecular web: endoplasmic reticulum stress, inflammation, and oxidative stress
    • PID: 25120434
    • Chaudhari N, Talwar P, Parimisetty A, et al. A molecular web: endoplasmic reticulum stress, inflammation, and oxidative stress. Front Cell Neurosci. 2014;8:213.
    • (2014) Front Cell Neurosci , vol.8 , pp. 213
    • Chaudhari, N.1    Talwar, P.2    Parimisetty, A.3
  • 29
    • 77954950112 scopus 로고    scopus 로고
    • Early inflammatory response during the development of right ventricular heart failure in a rat model
    • COI: 1:CAS:528:DC%2BC3cXotVWktLs%3D, PID: 20495202
    • Campian ME, Hardziyenka M, de Bruin K, et al. Early inflammatory response during the development of right ventricular heart failure in a rat model. Eur J Heart Fail. 2010;12:653–8.
    • (2010) Eur J Heart Fail , vol.12 , pp. 653-658
    • Campian, M.E.1    Hardziyenka, M.2    de Bruin, K.3
  • 30
    • 84874438834 scopus 로고    scopus 로고
    • The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress
    • COI: 1:CAS:528:DC%2BC38XpvFChsLk%3D, PID: 22268789
    • Jager R, Bertrand MJ, Gorman AM, et al. The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress. Biol Cell. 2012;104:259–70.
    • (2012) Biol Cell , vol.104 , pp. 259-270
    • Jager, R.1    Bertrand, M.J.2    Gorman, A.M.3
  • 31
    • 46649111986 scopus 로고    scopus 로고
    • Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene
    • COI: 1:CAS:528:DC%2BD1cXls12lsbw%3D, PID: 18319259
    • Belmont PJ, Tadimalla A, Chen WJ, et al. Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene. J Biol Chem. 2008;283:14012–21.
    • (2008) J Biol Chem , vol.283 , pp. 14012-14021
    • Belmont, P.J.1    Tadimalla, A.2    Chen, W.J.3
  • 32
    • 6344250896 scopus 로고    scopus 로고
    • Natriuretic peptides, respiratory disease, and the right heart
    • COI: 1:CAS:528:DC%2BD2cXhtValur3K, PID: 15486400
    • Yap LB, Mukerjee D, Timms PM, et al. Natriuretic peptides, respiratory disease, and the right heart. Chest. 2004;126:1330–6.
    • (2004) Chest , vol.126 , pp. 1330-1336
    • Yap, L.B.1    Mukerjee, D.2    Timms, P.M.3
  • 33
    • 4043084261 scopus 로고    scopus 로고
    • The use of the Doppler pulmonary artery velocity time integral to optimize placement of a ventricular pacing lead in a patient with Ebstein's anomaly
    • PID: 15273455
    • Pai RK, Kedia A, Hsu PY, et al. The use of the Doppler pulmonary artery velocity time integral to optimize placement of a ventricular pacing lead in a patient with Ebstein's anomaly. J Interv Card Electrophysiol. 2004;11:55–7.
    • (2004) J Interv Card Electrophysiol , vol.11 , pp. 55-57
    • Pai, R.K.1    Kedia, A.2    Hsu, P.Y.3
  • 34
    • 0038080911 scopus 로고    scopus 로고
    • Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation
    • COI: 1:CAS:528:DC%2BD3sXkt1Wisb8%3D, PID: 12665508
    • Reddy RK, Mao C, Baumeister P, et al. Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation. J Biol Chem. 2003;278:20915–24.
    • (2003) J Biol Chem , vol.278 , pp. 20915-20924
    • Reddy, R.K.1    Mao, C.2    Baumeister, P.3
  • 35
    • 84856111924 scopus 로고    scopus 로고
    • The unfolded protein response: controlling cell fate decisions under ER stress and beyond
    • COI: 1:CAS:528:DC%2BC38XnvVeltQ%3D%3D, PID: 22251901
    • Hetz C. The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat Rev Mol Cell Biol. 2012;13:89–102.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 89-102
    • Hetz, C.1
  • 36
    • 77953356311 scopus 로고    scopus 로고
    • ATF6 is important under both pathological and physiological states in the heart
    • COI: 1:CAS:528:DC%2BC3cXmslCnt78%3D, PID: 20380836
    • Toko H, Takahashi H, Kayama Y, et al. ATF6 is important under both pathological and physiological states in the heart. J Mol Cell Cardiol. 2010;49:113–20.
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 113-120
    • Toko, H.1    Takahashi, H.2    Kayama, Y.3
  • 37
    • 33745019669 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6
    • COI: 1:CAS:528:DC%2BD28XktVymt74%3D, PID: 16601230
    • Martindale JJ, Fernandez R, Thuerauf D, et al. Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6. Circ Res. 2006;98:1186–93.
    • (2006) Circ Res , vol.98 , pp. 1186-1193
    • Martindale, J.J.1    Fernandez, R.2    Thuerauf, D.3
  • 38
    • 34548189283 scopus 로고    scopus 로고
    • ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress
    • COI: 1:CAS:528:DC%2BD2sXhtVels73M, PID: 17765679
    • Wu J, Rutkowski DT, Dubois M, et al. ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress. Dev Cell. 2007;13:351–64.
    • (2007) Dev Cell , vol.13 , pp. 351-364
    • Wu, J.1    Rutkowski, D.T.2    Dubois, M.3
  • 39
    • 0036306437 scopus 로고    scopus 로고
    • Serial noninvasive assessment of progressive pulmonary hypertension in a rat model
    • COI: 1:CAS:528:DC%2BD38XlsVCksL4%3D, PID: 12063310
    • Jones JE, Mendes L, Rudd MA, et al. Serial noninvasive assessment of progressive pulmonary hypertension in a rat model. Am J Physiol Heart Circ Physiol. 2002;283(1):H364–71.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , Issue.1 , pp. H364-H371
    • Jones, J.E.1    Mendes, L.2    Rudd, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.