Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease

Cell Stem Cell

Volumn 19, Issue 5, 2016, Pages 628-642

  Kramann, Rafael ^a,b   Goettsch, Claudia ^b   Wongboonsin, Janewit ^c   Iwata, Hiroshi ^b   Schneider, Rebekka K ^a,b   Kuppe, Christoph ^a   Kaesler, Nadine ^a   Chang Panesso, Monica ^c   Machado, Flavia G ^c   Gratwohl, Susannah ^c   Madhurima, Kaushal ^c   Hutcheson, Joshua D ^b   Jain, Sanjay ^c   Aikawa, Elena ^b,d   Humphreys, Benjamin D ^c  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; ALPHA SMOOTH MUSCLE ACTIN; APOLIPOPROTEIN E; CALPONIN; CD31 ANTIGEN; CD34 ANTIGEN; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SMOOTHELIN; SONIC HEDGEHOG PROTEIN; STEM CELL ANTIGEN 1; TAMOXIFEN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA; TRANSGELIN; TROPOMYOSIN; VIMENTIN; ATAXIN 1; BIOLOGICAL MARKER; GLI PROTEIN, MOUSE; GLI1 PROTEIN, HUMAN; SHH PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ARCH; ARTERIOSCLEROSIS; ARTERY INJURY; ARTERY WALL; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL CALCIFICATION; BLOOD VESSEL WALL; CARTILAGE CELL; CELL DIFFERENTIATION; CELL EXPANSION; CELL ISOLATION; CELL MIGRATION; CELL PLASTICITY; CELL PROLIFERATION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; FEMORAL ARTERY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MOUSE; NEOINTIMA; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; VASCULAR SMOOTH MUSCLE CELL; ADVENTITIA; AGED; ANIMAL; CELL DEDIFFERENTIATION; CELL LINEAGE; CELL MOTION; CHRONIC KIDNEY FAILURE; COMPLICATION; FEMALE; MALE; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; SMOOTH MUSCLE CELL; STEM CELL; TRANSGENIC MOUSE; VASCULAR REMODELING; VASCULAR SMOOTH MUSCLE;

ADVENTITIA; AGED; ANIMALS; ANTIGENS, CD34; ATAXIN-1; BIOMARKERS; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; HEDGEHOG PROTEINS; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NEOINTIMA; OSTEOBLASTS; PLAQUE, ATHEROSCLEROTIC; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RENAL INSUFFICIENCY, CHRONIC; STEM CELLS; VASCULAR CALCIFICATION; VASCULAR REMODELING; ZINC FINGER PROTEIN GLI1;

EID: 84994803382     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.08.001     Document Type: Article

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