Density, Serotype Diversity, and Fitness of Streptococcus pneumoniae in Upper Respiratory Tract Cocolonization with Nontypeable Haemophilus influenzae

Journal of Infectious Diseases

Volumn 214, Issue 9, 2016, Pages 1411-1420

  Lewnard, Joseph A ^a   Huppert, Amit ^b   Givon Lavi, Noga ^e,f   Pettigrew, Melinda M ^a   Regev Yochay, Gili ^c,d   Dagan, Ron ^f   Weinberger, Daniel M ^a  

^a YALE UNIVERSITY   (United States)

^b Section of Biostatistics   (Israel)

^c GERTNER INSTITUTE FOR EPIDEMIOLOGY AND HEALTH POLICY RESEARCH   (Israel)

^d SHEBA MEDICAL CENTER   (Israel)

^e BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^f BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

carriage; coinfection; interspecies interaction; nasopharynx; nontypeable Haemophilus influenzae; Streptococcus pneumoniae

Indexed keywords

PNEUMOCOCCUS VACCINE; VACCINE;

AGE DISTRIBUTION; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL VIRULENCE; BACTERIUM EXAMINATION; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATION; BEDOUIN; CHILD; CONTROLLED STUDY; ETHNIC DIFFERENCE; HUMAN; HUMAN EXPERIMENT; INFANT; JEW; MICROBIAL DIVERSITY; NASOPHARYNX; NONTYPEABLE HAEMOPHILUS INFLUENZAE; NORMAL HUMAN; ORGANISMAL INTERACTION; OROPHARYNX; POPULATION RESEARCH; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEROTYPE; STREPTOCOCCUS PNEUMONIAE; UPPER RESPIRATORY TRACT; FEMALE; GROWTH, DEVELOPMENT AND AGING; HAEMOPHILUS INFECTION; HAEMOPHILUS INFLUENZAE; HETEROZYGOTE; IMMUNOLOGY; MALE; MICROBIOLOGY; MIXED INFECTION; OTITIS MEDIA; PNEUMOCOCCAL INFECTION; RESPIRATORY TRACT INFECTION; VIROLOGY;

CARRIER STATE; CHILD, PRESCHOOL; COINFECTION; FEMALE; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HUMANS; INFANT; MALE; NASOPHARYNX; OROPHARYNX; OTITIS MEDIA; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; RESPIRATORY TRACT INFECTIONS; SEROGROUP; STREPTOCOCCUS PNEUMONIAE; VACCINES, CONJUGATE;

EID: 84994765138     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiw381     Document Type: Article

References (45)

1. Rovers MM. The burden of otitis media. Vaccine 2008; 26:G2-4
2. Li MG, Hotez PJ, Vrabec JT, Donovan DT. Is Chronic Suppurative Otitis Media a Neglected Tropical Disease? PLoS Negl Trop Dis 2015; 9:e0003485
3. Barkai G, Leibovitz E, Givon-Lavi N, Dagan R. Potential contribution by nontypable Haemophilus influenzae in protracted and recurrent acute otitis media. Pediatr Infect Dis J 2009; 28:466-71
4. Dagan R, Pelton S, Bakaletz L, Cohen R. Prevention of early episodes of otitis media by pneumococcal vaccines might reduce progression to complex disease. Lancet Infect Dis 2016; 16:480-92
5. Dagan R, Leibovitz E, Greenberg D, Bakaletz L, Givon-Lavi N. Mixed pneumococcal-nontypeable Haemophilus influenzae otitis media is a distinct clinical entity with unique epidemiologic characteristics and pneumococcal serotype distribution. J Infect Dis 2013; 208:1152-60
6. Shak JR, Vidal JE, Klugman KP. Influence of bacterial interactions on pneumococcal colonization of the nasopharynx. Trends Microbiol 2013; 21:129-35
7. Chien Y-W, Vidal JE, Grijalva CG, et al. Density interactions among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the nasopharynx of young Peruvian children. Pediatr Infect Dis J 2013; 32:72-7
8. Lewnard JA, Givon-Lavi N, Huppert A, et al. Epidemiological markers for interactions among Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus in upper respiratory tract carriage. J Infect Dis 2016; 213:1596-605
9. Bosch AATM, Biesbroek G, Trzcinski K, Sanders EAM, Bogaert D. Viral and Bacterial Interactions in the Upper Respiratory Tract. PLoS Pathog 2013; 9:e1003057
10. Weimer KE, Armbruster CEE, Juneau RA, Hong W, Pang B, Swords WEE. Coinfection with Haemophilus influenzae promotes pneumococcal biofilm formation during experimental otitis media and impedes the progression of pneumococcal disease. J Infect Dis 2010; 202:1068-75
11. Lysenko ES, Lijek RS, Brown SP,Weiser JN.Within-host competition drives selection for the capsule virulence determinant of Streptococcus pneumoniae. Curr Biol 2010; 20:1222-6
12. Lysenko ES, Ratner AJ, Nelson AL,Weiser JN. The role of innate immune responses in the outcome of interspecies competition for colonization of mucosal surfaces. PLoS Pathog 2005; 1:0003-11
13. Margolis E, Yates A, Levin BR. The ecology of nasal colonization of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus: the role of competition and interactions with host's immune response. BMC Microbiol 2010; 10:59
14. Bogaert D, De Groot R, Hermans PWM. Streptococcus pneumoniae colonisation: The key to pneumococcal disease. Lancet Infect Dis 2004; 4:144-54
15. Hathaway LJ, Brugger SD, Morand B, et al. Capsule type of Streptococcus pneumoniae determines growth phenotype. PLoS Pathog 2012; 8:e1002574
16. Kadioglu A, Weiser JN, Paton JC, Andrew PW. The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nat Rev Microbiol 2008; 6:288-301
17. Weinberger DM, Trzciński K, Lu Y-J, et al. Pneumococcal capsular polysaccharide structure predicts serotype prevalence. PLoS Pathog 2009; 5:e1000476
18. Shouval DS, Greenberg D, Givon-Lavi N, Porat N, Dagan R. Site-specific disease potential of individual Streptococcus pneumoniae serotypes in pediatric invasive disease, acute otitis media and acute conjunctivitis. Pediatr Infect Dis J 2006; 25:602-7
19. Levy A, Fraser D, Vardi H, Dagan R. Hospitalizations for infectious diseases in Jewish and Bedouin children in southern Israel. Eur J Epidemiol 1998; 14:179-86
20. Rosenthal J, Dagan R, Press J, Sofer S. Differences in the epidemiology of childhood community-acquired bacterial meningitis between two ethnic populations cohabiting in one geographic area. Pediatr Infect Dis J 1988; 7:630-3
21. Dagan R, Givon-Lavi N, Porat N, Greenberg D. The effect of an alternative reduced-dose infant schedule and a second year catch-up schedule with 7-valent pneumococcal conjugate vaccine on pneumococcal carriage: A randomized controlled trial. Vaccine 2012; 30:5132-40
22. Sleeman KL, Griffiths D, Shackley F, et al. Capsular serotype-specific attack rates and duration of carriage of Streptococcus pneumoniae in a population of children. J Infect Dis 2006; 194:682-8
23. Harboe ZB, Thomsen RW, Riis A, et al. Pneumococcal serotypes and mortality following invasive pneumococcal disease: A population-based cohort study. PLoS Med 2009; 6:e1000081
24. Cheng G, Yu Z, Huang JZ. The cluster bootstrap consistency in generalized estimating equations. J Multivar Anal 2013; 115:33-47
25. Simpson EH. Measurement of diversity. Nature 1949; 163:688
26. Cobey S, Lipsitch M. Pathogen diversity and hidden regimes of apparent competition. Am Nat 2013; 181:12-24
27. Trzcinski K, Li Y,Weinberger DM, et al. Effect of serotype on pneumococcal competition in a mouse colonization model. MBio 2015; 6:e00902-15
28. Murray CJL, Vos T, Lozano R, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380:2197-223
29. van Gils EJM, Veenhoven RH, Rodenburg GD, Hak E, Sanders EAM. Effect of 7-valent pneumococcal conjugate vaccine on nasopharyngeal carriage with Haemophilus influenzae and Moraxella catarrhalis in a randomized controlled trial. Vaccine 2011; 29:7595-8
30. Dunne EM, Manning J, Russell FM, Robins-Browne RM, Mulholland EK, Satzke C. Effect of pneumococcal vaccination on nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Fijian children. J Clin Microbiol 2012; 50:1034-8
31. Pericone CD, Overweg K, Hermans PW, Weiser JN. Inhibitory and bactericidal effects of hydrogen peroxide production by Streptococcus pneumoniae on other inhabitants of the upper respiratory tract. Infect Immun 2000; 68:3990-7
32. Cope EK, Goldstein-Daruech N, Kofonow JM, et al. Regulation of virulence gene expression resulting from Streptococcus pneumoniae and nontypeable Haemophilus influenzae interactions in chronic disease. PLoS One 2011; 6:16-8
33. Gasparoni A, Ciardelli L, Avanzini A, et al. Age-related changes in intracellular Th1/ Th2 cytokine production, immunoproliferative T lymphocyte response and natural killer cell activity in newborns, children and adults. Biol Neonate 2003; 84:297-303
34. Miyawaki T, Seki H, Taga K, Sato H, Taniguchi N. Dissociated production of interleukin-2 and immune (gamma) interferon by phytohaemagglutinin stimulated lymphocytes in healthy infants. Clin Exp Immunol 1985; 59:505-11
35. Rowe J, Macaubas C, Monger TM, et al. Antigen-specific responses to diphtheriatetanus-acellular pertussis vaccine in human infants are initially Th2 polarized. Infect Immun 2000; 68:3873-7
36. Malley R, Trzcinski K, Srivastava A, Thompson CM, Anderson PW, Lipsitch M. CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization. Proc Natl Acad Sci U S A 2005; 102:4848-53
37. Trzciński K, Thompson CM, Srivastava A, Basset A, Malley R, Lipsitch M. Protection against nasopharyngeal colonization by Streptococcus pneumoniae is mediated by antigen-specific CD4+ T cells. Infect Immun 2008; 76:2678-84
38. Sharma SK, Casey JR, Pichichero ME. Reduced memory CD4+ T-cell generation in the circulation of young children may contribute to the otitis-prone condition. J Infect Dis 2011; 204:645-53
39. Cobey S, Lipsitch M. Niche and neutral effects of acquired immunity permit coexistence of pneumococcal serotypes. Science 2012; 335:1376-80
40. Murphy TF, Brauer AL, Sethi S, Kilian M, Cai X, Lesse AJ. Haemophilus haemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae. J Infect Dis 2007; 195:81-9
41. Smith W, Grassle JF. Sampling properties of a family of diversity estimators. Biometrics 1977; 33:283-92
42. Madhi SA, Adrian P, Kuwanda L, Cutland C, Albrich WC, Klugman KP. Longterm effect of pneumococcal conjugate vaccine on nasopharyngeal colonization by Streptococcus pneumoniae-and associated interactions with Staphylococcus aureus and Haemophilus influenzae colonization-in HIV-Infected and HIVuninfected children. J Infect Dis 2007; 196:1662-6
43. McNally LM, Jeena PM, Gajee K, et al. Lack of association between the nasopharyngeal carriage of Streptococcus pneumoniae and Staphylococcus aureus in HIV-1-infected South African children. J Infect Dis 2006; 194: 385-90
44. Bogaert D, Nouwen J, Hermans PWM, Van Belkum A. Lack of interference between Streptococcus pneumoniae and Staphylococcus aureus in HIV-Infected Individuals? J Infect Dis 2006; 194:1617-8
45. Reiss-Mandel A, Regev-Yochay G. Staphylococcus aureus and Streptococcus pneumoniae interaction and response to pneumococcal vaccination: Myth or reality? Hum Vaccin Immunother 2016; 12:351-7