The effect of an alternative reduced-dose infant schedule and a second year catch-up schedule with 7-valent pneumococcal conjugate vaccine on pneumococcal carriage: A randomized controlled trial

Vaccine

Volumn 30, Issue 34, 2012, Pages 5132-5140

  Dagan, Ron ^a   Givon Lavi, Noga ^a   Porat, Nurith ^a   Greenberg, David ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Alternative schedule; Immune response; Pneumococcal carriage; Pneumococcal conjugate vaccine

Indexed keywords

IMMUNOGLOBULIN G; PNEUMOCOCCUS VACCINE;

ARTICLE; BACTERIUM CULTURE; BLOOD SAMPLING; COMMUNITY; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; IMMUNOGENICITY; INFANT; MAJOR CLINICAL STUDY; MALE; OPEN STUDY; PNEUMOCOCCAL INFECTION; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEROTYPE; SOCIOECONOMICS;

ANTIBODIES, BACTERIAL; CARRIER STATE; FEMALE; HUMANS; IMMUNIZATION SCHEDULE; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN G; INFANT; MALE; NASOPHARYNX; OROPHARYNX; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; PREVALENCE; SEROTYPING; STREPTOCOCCUS PNEUMONIAE; TIME FACTORS; VACCINATION;

EID: 84863781020     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.05.059     Document Type: Article

References (33)

1. EMEA Annex I. Summary of product characteristics. Prevenar suspension for injection, pneumococcal saccharide conjugated vaccine adsorbed 2012, [accessed March 2012]. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000323/WC500041563.pdf.
2. Givon-Lavi N., Greenberg D., Dagan R. Immunogenicity of alternative regimens of the conjugated 7-valent pneumococcal vaccine-a randomized controlled trial. Pediatr. Infect Dis J 2010, 29:756-762.
3. Fritzell B., Fletcher M.A. Pneumococcal polysaccharide-protein (CRM197) conjugate vaccines, 7- or 9-valent, in the 2+1 schedule. Expert Rev Vaccines 2011, 10:263-290.
4. Azzari C., Resti M. Reduction of carriage and transmission of Streptococcus pneumoniae: the beneficial side effect of pneumococcal conjugate vaccine. Clin Infect Dis 2008, 47:997-999.
5. Kayhty H., Auranen K., Nohynek H., Dagan R., Makela H. (PneumoCarr) atPCG. Nasopharyngeal colonization: a target for pneumococcal vaccination. Expert Rev Vaccines 2006, 5:651-668.
6. Pilishvili T., Lexau C., Farley M.M., Hadler J., Harrison L.H., Bennett N.M., et al. Sustained reductions in invasive pneumococcal disease in the era of conjugate vaccine. J Infect Dis 2010, 201:32-41.
7. Ota M.O., Akinsola A., Townend J., Antonio M., Enwere G., Nsekpong D., et al. The immunogenicity and impact on nasopharyngeal carriage of fewer doses of conjugate pneumococcal vaccine immunization schedule. Vaccine 2011, 29:2999-3007.
8. van Gils E.J., Veenhoven R.H., Hak E., Rodenburg G.D., Bogaert D., Ijzerman E.P., et al. Effect of reduced-dose schedules with 7-valent pneumococcal conjugate vaccine on nasopharyngeal pneumococcal carriage in children: a randomized controlled trial. JAMA 2009, 302:159-167.
9. Russell F.M., Carapetis J.R., Satzke C., Tikoduadua L., Waqatakirewa L., Chandra R., et al. Pneumococcal nasopharyngeal carriage following reduced doses of a 7-valent pneumococcal conjugate vaccine and a 23-valent pneumococcal polysaccharide vaccine booster. Clin Vaccine Immunol 2011, 17:1970-1976.
10. Flasche S., Van Hoek A., Sheasby E., Waight P., Andrews N., Sheppard C., et al. Effect of pneumococcal conjugate vaccination on serotype-specific carriage and invasive disease in England: a cross-sectional study. PLoS Med 2011, 8(4):e1001017. 10.1371/journal.pmed.1001017.
11. Spijkerman J, van Gils EJ, Veenhoven RH, Hak E, Yzerman EP, van der Ende A, et al. Carriage of Streptococcus pneumoniae 3 years after Start of vaccination program, the Netherlands. Emerg Infect Dis 17:584-91.
12. Vestrheim D.F., Hoiby E.A., Bergsaker M.R., Ronning K., Aaberge I.S., Caugant D.A. Indirect effect of conjugate pneumococcal vaccination in a 2+1 dose schedule. Vaccine 2010, 28:2214-2221.
13. Statistical Abstracts of Israel, 1998. No. 49. Central Bureau of Statistics. Jerusalem: Hemed Press Ltd. 1998.
14. Barkai G., Greenberg D., Givon-Lavi N., Dreifuss E., Vardy D., Dagan R. Community prescribing and resistant Streptococcus pneumoniae. Emerg Infect Dis 2005, 11:829-837.
15. Austrian R. The quellung reaction, a neglected microbiologic technique. Mt Sinai J Med 1976, 43:699-709.
16. Quataert S.A., Kirch C.S., Wiedl L.J., Phipps D.C., Strohmeyer S., Cimino C.O., et al. Assignment of weight-based antibody units to a human antipneumococcal standard reference serum, lot 89-S. Clin Diagn Lab Immunol 1995, 2:590-597.
17. Concepcion N.F., Frasch C.E. Pneumococcal type 22f polysaccharide absorption improves the specificity of a pneumococcal-polysaccharide enzyme-linked immunosorbent assay. Clin Diagn Lab Immunol 2001, 8:266-272.
18. Quataert S.A., Rittenhouse-Olson K., Kirch C.S., Hu B., Secor S., Strong N., et al. Assignment of weight-based antibody units for 13 serotypes to a human antipneumococcal standard reference serum, lot 89-S(f). Clin Diagn Lab Immunol 2004, 11:1064-1069.
19. Goldblatt D., Hussain M., Andrews N., Ashton L., Virta C., Melegaro A., et al. Antibody responses to nasopharyngeal carriage of Streptococcus pneumoniae in adults: a longitudinal household study. J Infect Dis 2005, 192:387-393.
20. Millar E.V., O'Brien K.L., Bronsdon M.A., Madore D., Hackell J.G., Reid R., et al. Anticapsular serum antibody concentration and protection against pneumococcal colonization among children vaccinated with 7-valent pneumococcal conjugate vaccine. Clin Infect Dis 2007, 44:1173-1179.
21. Dagan R., Givon-Lavi N., Fraser D., Lipsitch M., Siber G.R., Kohberger R. Serum serotype-specific pneumococcal anticapsular immunoglobulin G concentrations after immunization with a 9-valent conjugate pneumococcal vaccine correlate with nasopharyngeal acquisition of pneumococcus. J Infect Dis 2005, 192:367-376.
22. Becker N.G., Starczak D.N. The effect of random vaccine response on the vaccination coverage required to prevent epidemics. Math Biosci 1998, 154:117-135.
23. Rinta-Kokko H., Dagan R., Givon-Lavi N., Auranen K. Estimation of vaccine efficacy against acquisition of pneumococcal carriage. Vaccine 2009, 27:3831-3837.
24. W.H.O. Meeting of the strategic advisory groups of experts on immunization, November 2010 - summary, conclusions and recommendations. Wkly Epidemiol Rec 2011, 86:1-16.
25. W.H.O. Meeting of the Strategic Advisory Group of Experts on Immunization, November 2011 - conclusions and recommendations. Wkly Epidemiol Rec 2012, 87:1-16.
26. Goldblatt D., Southern J., Ashton L., Andrews N., Woodgate S., Burbidge P., et al. Immunogenicity of a reduced schedule of pneumococcal conjugate vaccine in healthy infants and correlates of protection for serotype 6B in the United Kingdom. Pediatr Infect Dis J 2010, 29:401-405.
27. Pelton S.I., Weycker D., Klein J.O., Strutton D., Ciuryla V., Oster G. 7-Valent pneumococcal conjugate vaccine and lower respiratory tract infections: effectiveness of a 2-dose versus 3-dose primary series. Vaccine 2010, 28:1575-1582.
28. Patrzalek M., Albrecht P., Sobczynski M. Significant decline in pneumonia admission rate after the introduction of routine 2+1 dose schedule heptavalent pneumococcal conjugate vaccine (PCV7) in children under 5 years of age in Kielce, Poland. Eur J Clin Microbiol Infect Dis 2010, 29:787-792.
29. Durando P., Crovari P., Ansaldi F., Sticchi L., Sticchi C., Turello V., et al. Universal childhood immunisation against Streptococcus pneumoniae: the five-year experience of Liguria Region, Italy. Vaccine 2009, 27:3459-3462.
30. De Wals P., Robin E., Fortin E., Thibeault R., Ouakki M., Douville-Fradet M. Pneumonia after implementation of the pneumococcal conjugate vaccine program in the province of Quebec, Canada. Pediatr Infect Dis J 2008, 27:963-968.
31. Vestrheim D.F., Hoiby E.A., Aaberge I.S., Caugant D.A. Impact of a pneumococcal conjugate vaccination program on carriage among children in Norway. Clin Vaccine Immunol 2010, 17:325-334.
32. Millar E.V., Watt J.P., Bronsdon M.A., Dallas J., Reid R., Santosham M., et al. Indirect effect of 7-valent pneumococcal conjugate vaccine on pneumococcal colonization among unvaccinated household members. Clin Infect Dis 2008, 47:989-996.
33. da Gloria Carvalho M., Pimenta F.C., Jackson D., Roundtree A., Ahmad Y., Millar E.V., et al. Revisiting pneumococcal carriage by use of broth enrichment and PCR techniques for enhanced detection of carriage and serotypes. J Clin Microbiol 2010, 48:1611-1618.