Functional Diversity of Cytomegalovirus-Specific T Cells Is Maintained in Older People and Significantly Associated with Protein Specificity and Response Size

Journal of Infectious Diseases

Volumn 214, Issue 9, 2016, Pages 1430-1437

  Bajwa, Martha ^a   Vita, Serena ^b   Vescovini, Rosanna ^c   Larsen, Martin ^d,e   Sansoni, Paolo ^c   Terrazzini, Nadia ^f   Caserta, Stefano ^a   Thomas, David ^a   Davies, Kevin A ^a   Smith, Helen ^a   Kern, Florian ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF PARMA   (Italy)

^d Assistance publique Hôpitaux de Paris   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^f UNIVERSITY OF BRIGHTON   (United Kingdom)

Author keywords

CD4+ T cells; CMV target proteins; cytomegalovirus; T cell polyfunctionality

Indexed keywords

ANTIGEN; CD107 ANTIGEN; CD40 LIGAND; GAMMA INTERFERON; INTERLEUKIN 2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOMEGALOVIRUS; FEMALE; FLOW CYTOMETRY; HUMAN; INFORMED CONSENT; LIMIT OF QUANTITATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SPECIFICITY; PROTEIN TARGETING; UNITED KINGDOM; VERY ELDERLY; YOUNG ADULT; CYTOMEGALOVIRUS INFECTION; IMMUNOLOGY; MIDDLE AGED;

ADULT; AGED; AGED, 80 AND OVER; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; FEMALE; FLOW CYTOMETRY; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-2; MALE; MIDDLE AGED; TUMOR NECROSIS FACTOR-ALPHA; UNITED KINGDOM; YOUNG ADULT;

EID: 84994753697     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiw371     Document Type: Article

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