The cyclin-dependent kinase inhibitor AT7519 accelerates neutrophil apoptosis in sepsis-related acute respiratory distress syndrome

Thorax

Volumn 72, Issue 2, 2017, Pages 182-185

  Dorward, David A ^a   Felton, Jennifer M ^a   Robb, Calum T ^a   Craven, Thomas ^a   Kipari, Tiina ^a   Walsh, Timothy S ^a,b   Haslett, Christopher ^a   Kefala, Kallirroi ^b   Rossi, Adriano G ^a   Lucas, Christopher D ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AT 7519; C REACTIVE PROTEIN; CASPASE 3; CYCLIN DEPENDENT KINASE INHIBITOR; INTERLEUKIN 6; INTERLEUKIN 8; PROTEIN MCL 1; UNCLASSIFIED DRUG; 4-(2,6-DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXYLIC ACID PIPERIDIN-4-YLAMIDE; BIOLOGICAL MARKER; CYTOKINE; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE;

ADULT RESPIRATORY DISTRESS SYNDROME; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; ARTIFICIAL VENTILATION; CELL SURVIVAL; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; MALE; NEUTROPHIL; SEPSIS; ADULT; AGED; BLOOD; CASE CONTROL STUDY; COMPLICATION; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; MIDDLE AGED; RESPIRATORY DISTRESS SYNDROME, ADULT; SURVIVAL RATE;

ADULT; AGED; APOPTOSIS; BIOMARKERS; CASE-CONTROL STUDIES; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; MIDDLE AGED; NEUTROPHILS; PIPERIDINES; PYRAZOLES; RESPIRATORY DISTRESS SYNDROME, ADULT; SEPSIS; SURVIVAL RATE;

EID: 84994709947     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2016-209229     Document Type: Article

References (13)

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