Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 44, 2016, Pages 12444-12449

  Kikuchi, Sotaro ^a,b   Borek, Dominika M ^c   Otwinowski, Zbyszek ^c   Tomchick, Diana R ^c   Yu, Hongtao ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cohesin loading; Cohesinopathy; HEAT repeat; Transcription; X ray crystallography

Indexed keywords

ADAPTOR PROTEIN; ADENOSINE TRIPHOSPHATASE; COHESIN; SISTER CHROMATID COHESION 1; SISTER CHROMATID COHESION 2; SISTER CHROMATID COHESION 3; SISTER CHROMATID COHESION 4; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; FUNGAL PROTEIN; NONHISTONE PROTEIN; PROTEIN BINDING;

AMINO TERMINAL SEQUENCE; CHAETOMIUM; CHAETOMIUM THERMOPHILUM; CHROMOSOME 1; CHROMOSOME 3; CHROMOSOME SEGREGATION; COHESINOPATHY; CONFERENCE PAPER; CRYSTAL STRUCTURE; DEVELOPMENTAL DISORDER; DISSOCIATION; DNA BINDING; DNA REPAIR; FISSION YEAST; ISOTHERMAL TITRATION CALORIMETRY; LACHANCEA THERMOTOLERANS; MISSENSE MUTATION; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SISTER CHROMATID; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CHEMISTRY; CHROMATID; GENETICS; METABOLISM; MOLECULAR MODEL; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; CELL CYCLE PROTEINS; CHAETOMIUM; CHROMATIDS; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOME SEGREGATION; CRYSTALLOGRAPHY, X-RAY; FUNGAL PROTEINS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN DOMAINS; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84994665932     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1611333113     Document Type: Article

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