Optogenetic activation of Dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 45, 2016, Pages 12826-12831

  Taylor, Norman E ^a,b,c   Van Dort, Christa J ^a,b,c   Kenny, Jonathan D ^a,c   Pei, Junzhu ^a,c   Guidera, Jennifer A ^a,c   Vlasov, Ksenia Y ^a,c   Lee, Justin T ^a,c   Boyden, Edward S ^c,d,e   Brown, Emery N ^a,b,c,e   Solt, Ken ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e Massachusetts Institute of Technology   (United States)

Author keywords

Anesthesia; Arousal; Dopamine; Optogenetics; Ventral tegmental area

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CHANNELRHODOPSIN 2; CRE RECOMBINASE; ISOFLURANE; RHODOPSIN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; VIRUS VECTOR;

AROUSAL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EGO DEVELOPMENT; ELECTROENCEPHALOGRAM; ELECTROMYOGRAPHY; ELECTROSTIMULATION; GENE ACTIVATION; GENERAL ANESTHESIA; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; OPTOGENETICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RESUSCITATION; RIGHTING REFLEX; VENTRAL TEGMENTUM; VIRUS EXPRESSION;

EID: 84994528766     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1614340113     Document Type: Article

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