Linkage disequilibrium amongst ITGA2B and ITGB3 gene variants in patients with Glanzmann thrombasthenia confirms that most disease-causing mutations are recent

British Journal of Haematology

Volumn 175, Issue 4, 2016, Pages 686-695

  Pillois, Xavier ^a,b   Nurden, Alan T ^b  

^a Ctr Geriatrie Ctr Hosp Univ B   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

genetic variants; Glanzmann thrombasthenia; ITGA2B gene; ITGB3 gene

Indexed keywords

ARTICLE; CONTROLLED STUDY; GENE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; GEOGRAPHY; GLANZMANN DISEASE; HAPLOGROUP; HAPLOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; INTRON; ITGA2B GENE; ITGB3 GENE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; COHORT ANALYSIS; GENETIC DRIFT; GENETIC POLYMORPHISM; GENETIC VARIATION; GENETICS; GENOTYPE; MUTATION; THROMBASTHENIA;

ALPHA2 INTEGRIN; BETA3 INTEGRIN; ITGB3 PROTEIN, HUMAN;

ALLELES; COHORT STUDIES; GENE FREQUENCY; GENETIC DRIFT; GENETIC VARIATION; GENOTYPE; HAPLOTYPES; HUMANS; INTEGRIN ALPHA2; INTEGRIN BETA3; LINKAGE DISEQUILIBRIUM; MUTATION; POLYMORPHISM, GENETIC; THROMBASTHENIA;

EID: 84994464070     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.14283     Document Type: Article

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