A review of wave mechanics in the pulmonary artery with an emphasis on wave intensity analysis

Acta Physiologica

Volumn 218, Issue 4, 2016, Pages 239-249

  Su, J ^a,b   Hilberg, O ^c   Howard, L ^b   Simonsen, U ^a   Hughes, A D ^b,d  

^a AARHUS UNIVERSITY   (Denmark)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

pulmonary circulation; pulse wave velocity; wave intensity analysis; wave reflection

Indexed keywords

BLOOD VESSEL PARAMETERS; CANINE MODEL; HUMAN; LUNG MECHANICS; NONHUMAN; OVINE MODEL; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY ARTERY WAVE; PULMONARY HYPERTENSION; REVIEW; WAVE INTENSITY ANALYSIS; ANIMAL; HEMODYNAMICS; PHYSIOLOGY; PULSE WAVE;

ANIMALS; HEMODYNAMICS; HUMANS; PULMONARY ARTERY; PULSE WAVE ANALYSIS;

EID: 84994422962     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12803     Document Type: Review

References (76)

1. Aguado-Sierra, J., Parker, K.H., Davies, J.E., Francis, D., Hughes, A.D. & Mayet, J. 2006. Arterial pulse wave velocity in coronary arteries. Conf Proc IEEE Eng Med Biol Soc 1, 867–870.
2. Alastruey, J. 2006. Numerical modelling of pulse wave propagation in the cardiovascular system: development, validation and clinical applications. PhD thesis.
3. Baksi, J., Davies, J.E., Hadjiloizou, N., Baruah, R., Unsworth, B., Foale, R.A., Korolkova, O., Siggers, J.H., Francis, D.P., Mayet, J., Parker, K.H. & Hughes, A.D. 2016. Attenuation of reflected waves in man during retrograde propagation from femoral artery to proximal aorta. Int J Cardiol 202, 441–445.
4. Ben-Shlomo, Y., Spears, M., Boustred, C., May, M., Anderson, S.G., Benjamin, E.J., Boutouyrie, P., Cameron, J., Chen, C.H., Cruickshank, J.K. et al. 2014. Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol 63, 636–646.
5. Bleasdale, R.A., Mumford, C.E., Campbell, R.I., Fraser, A.G., Jones, C.J. & Frenneaux, M.P. 2003. Wave intensity analysis from the common carotid artery: a new noninvasive index of cerebral vasomotor tone. Heart Vessels 18, 202–206.
6. Bouwmeester, J.C., Belenkie, I., Shrive, N.G. & Tyberg, J.V. 2014. Wave reflections in the pulmonary arteries analysed with the reservoir-wave model. J Physiol 592, 3053–3062.
7. Brin, K.P. & Yin, F.C. 1984. Effect of nitroprusside on wave reflections in patients with heart failure. Ann Biomed Eng 12, 135–150.
8. Caro, C.G. & Saffman, P.G. 1965. Extensibility of blood vessels in isolated rabbit lungs. J Physiol 178, 193–210.
9. Castelain, V., Herve, P., Lecarpentier, Y., Duroux, P., Simonneau, G. & Chemla, D. 2001. Pulmonary artery pulse pressure and wave reflection in chronic pulmonary thromboembolism and primary pulmonary hypertension. J Am Coll Cardiol 37, 1085–1092.
10. Champion, H.C., Michelakis, E.D. & Hassoun, P.M. 2009. Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications. Circulation 120, 992–1007.
11. Chan, S.Y. & Loscalzo, J. 2008. Pathogenic mechanisms of pulmonary arterial hypertension. J Mol Cell Cardiol 44, 14–30.
12. Chemla, D., Castelain, V., Herve, P., Lecarpentier, Y. & Brimioulle, S. 2002. Haemodynamic evaluation of pulmonary hypertension. Eur Respir J 20, 1314–1331.
13. Davies, J.E., Whinnett, Z.I., Francis, D.P., Manisty, C.H., Aguado-Sierra, J., Willson, K., Foale, R.A., Malik, I.S., Hughes, A.D., Parker, K.H. & Mayet, J. 2006a. Evidence of a dominant backward-propagating “suction” wave responsible for diastolic coronary filling in humans, attenuated in left ventricular hypertrophy. Circulation 113, 1768–1778.
14. Davies, J.E., Whinnett, Z.I., Francis, D.P., Willson, K., Foale, R.A., Malik, I.S., Hughes, A.D., Parker, K.H. & Mayet, J. 2006b. Use of simultaneous pressure and velocity measurements to estimate arterial wave speed at a single site in humans. Am J Physiol Heart Circ Physiol 290, H878–H885.
15. Davies, J.E., Alastruey, J., Francis, D.P., Hadjiloizou, N., Whinnett, Z.I., Manisty, C.H., Aguado-Sierra, J., Willson, K., Foale, R.A., Malik, I.S., Hughes, A.D., Parker, K.H. & Mayet, J. 2012. Attenuation of wave reflection by wave entrapment creates a “horizon effect” in the human aorta. Hypertension 60, 778–785.
16. Dwyer, N., Yong, A.C. & Kilpatrick, D. 2012. Variable open-end wave reflection in the pulmonary arteries of anesthetized sheep. J Physiol Sci 62, 21–28.
17. Fujimoto, S., Mizuno, R., Saito, Y. & Nakamura, S. 2004. Clinical application of wave intensity for the treatment of essential hypertension. Heart Vessels 19, 19–22.
18. Galie, N., Manes, A., Negro, L., Palazzini, M., Bacchi-Reggiani, M.L. & Branzi, A. 2009. A meta-analysis of randomized controlled trials in pulmonary arterial hypertension. Eur Heart J 30, 394–403.
19. Ghiadoni, L., Bruno, R.M., Stea, F., Virdis, A. & Taddei, S. 2009. Central blood pressure, arterial stiffness, and wave reflection: new targets of treatment in essential hypertension. Curr Hypertens Rep 11, 190–196.
20. Gozna, E.R., Marble, A.E., Shaw, A. & Holland, J.G. 1974. Age-related changes in the mechanics of the aorta and pulmonary artery of man. J Appl Physiol 36, 407–411.
21. Grant, D.A., Hollander, E., Skuza, E.M. & Fauchere, J.C. 1999. Interactions between the right ventricle and pulmonary vasculature in the fetus. J Appl Physiol (1985) 87, 1637–1643.
22. Guazzi, M. & Galie, N. 2012. Pulmonary hypertension in left heart disease. Eur Respir Rev 21, 338–346.
23. Hadjiloizou, N. 2010. The effect of regional ventricular dysfunction on coronary artery haemodynamics. PhD thesis.
24. Hanya, S. 2013. Validity of the water hammer formula for determining regional aortic pulse wave velocity: comparison of one-point and two-point (foot-to-foot) measurements using a multisensor catheter in human. Ann Vasc Dis 6, 150–158.
25. Hirata, K., Kawakami, M. & O'Rourke, M.F. 2006. Pulse wave analysis and pulse wave velocity: a review of blood pressure interpretation 100 years after Korotkov. Circ J 70, 1231–1239.
26. Hollander, E.H., Wang, J.J., Dobson, G.M., Parker, K.H. & Tyberg, J.V. 2001. Negative wave reflections in pulmonary arteries. Am J Physiol Heart Circ Physiol 281, H895–H902.
27. Hollander, E.H., Dobson, G.M., Wang, J.J., Parker, K.H. & Tyberg, J.V. 2004. Direct and series transmission of left atrial pressure perturbations to the pulmonary artery: a study using wave-intensity analysis. Am J Physiol Heart Circ Physiol 286, H267–H275.
28. Hughes, A.D. & Parker, K.H. 2009. Forward and backward waves in the arterial system: impedance or wave intensity analysis? Med Biol Eng Comput 47, 207–210.
29. Hughes, A.D., Parker, K.H. & Davies, J.E. 2008. Waves in arteries: a review of wave intensity analysis in the systemic and coronary circulations. Artery Res 2, 51–59.
30. Hughes, A.D., Davies, J.E. & Parker, K.H. 2013a. The importance of wave reflection: a comparison of wave intensity analysis and separation of pressure into forward and backward components. Conf Proc IEEE Eng Med Biol Soc 2013, 229–232.
31. Hughes, A.D., Park, C., Davies, J., Francis, D., McG Thom, S.A., Mayet, J. & Parker, K.H. 2013b. Limitations of augmentation index in the assessment of wave reflection in normotensive healthy individuals. PLoS One 8, e59371.
32. Khir, A.W., O'Brien, A., Gibbs, J.S. & Parker, K.H. 2001. Determination of wave speed and wave separation in the arteries. J Biomech 34, 1145–1155.
33. Kopec, G., Moertl, D., Jankowski, P., Tyrka, A., Sobien, B. & Podolec, P. 2013. Pulmonary artery pulse wave velocity in idiopathic pulmonary arterial hypertension. Can J Cardiol 29, 683–690.
34. Lammers, S.R., Kao, P.H., Qi, H.J., Hunter, K., Lanning, C., Albietz, J., Hofmeister, S., Mecham, R., Stenmark, K.R. & Shandas, R. 2008. Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves. Am J Physiol Heart Circ Physiol 295, H1451–H1459.
35. Lammers, S., Scott, D., Hunter, K., Tan, W., Shandas, R. & Stenmark, K.R. 2012. Mechanics and function of the pulmonary vasculature: implications for pulmonary vascular disease and right ventricular function. Compr Physiol 2, 295–319.
36. Laskey, W.K., Ferrari, V.A., Palevsky, H.I. & Kussmaul, W.G. 1993. Pulmonary artery hemodynamics in primary pulmonary hypertension. J Am Coll Cardiol 21, 406–412.
37. Lau, E.M., Manes, A., Celermajer, D.S. & Galie, N. 2011. Early detection of pulmonary vascular disease in pulmonary arterial hypertension: time to move forward. Eur Heart J 32, 2489–2498.
38. Lau, E.M., Abelson, D., Dwyer, N., Yu, Y., Ng, M.K. & Celermajer, D.S. 2014. Assessment of ventriculo-arterial interaction in pulmonary arterial hypertension using wave intensity analysis. Eur Respir J 43, 1804–1807.
39. Laurent, S., Boutouyrie, P., Asmar, R., Gautier, I., Laloux, B., Guize, L., Ducimetiere, P. & Benetos, A. 2001. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 37, 1236–1241.
40. Lighthill, J. 2001. Waves in Fluids. Cambridge University Press, Cambridge.
41. Macchia, A., Marchioli, R., Marfisi, R., Scarano, M., Levantesi, G., Tavazzi, L. & Tognoni, G. 2007. A meta-analysis of trials of pulmonary hypertension: a clinical condition looking for drugs and research methodology. Am Heart J 153, 1037–1047.
42. Mackenzie, I.S., Wilkinson, I.B. & Cockcroft, J.R. 2002. Assessment of arterial stiffness in clinical practice. QJM 95, 67–74.
43. Manisty, C.H., Zambanini, A., Parker, K.H., Davies, J.E., Francis, D.P., Mayet, J., McG Thom, S.A. & Hughes, A.D. 2009. Differences in the magnitude of wave reflection account for differential effects of amlodipine- versus atenolol-based regimens on central blood pressure: an Anglo-Scandinavian Cardiac Outcome Trial substudy. Hypertension 54, 724–730.
44. Manisty, C., Mayet, J., Tapp, R.J., Parker, K.H., Sever, P., Poulter, N.R., Thom, S.A. & Hughes, A.D. 2010. Wave reflection predicts cardiovascular events in hypertensive individuals independent of blood pressure and other cardiovascular risk factors: an ASCOT (Anglo-Scandinavian Cardiac Outcome Trial) substudy. J Am Coll Cardiol 56, 24–30.
45. Milnor, W.R., Conti, C.R., Lewis, K.B. & O'Rourke, M.F. 1969. Pulmonary arterial pulse wave velocity and impedance in man. Circ Res 25, 637–649.
46. Nakayama, Y., Nakanishi, N., Hayashi, T., Nagaya, N., Sakamaki, F., Satoh, N., Ohya, H. & Kyotani, S. 2001. Pulmonary artery reflection for differentially diagnosing primary pulmonary hypertension and chronic pulmonary thromboembolism. J Am Coll Cardiol 38, 214–218.
47. Nichols, W.W., O'Rourke, M.F. & Vlachopoulos, C. 2011. McDonald's Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles. Hodder Arnold, London.
48. Nie, M., Kobayashi, H., Sugawara, M., Tomita, T., Ohara, K. & Yoshimura, H. 2001. Helium inhalation enhances vasodilator effect of inhaled nitric oxide on pulmonary vessels in hypoxic dogs. Am J Physiol Heart Circ Physiol 280, H1875–H1881.
49. Niki, K., Sugawara, M., Uchida, K., Tanaka, R., Tanimoto, K., Imamura, H., Sakomura, Y., Ishizuka, N., Koyanagi, H. & Kasanuki, H. 1999. A noninvasive method of measuring wave intensity, a new hemodynamic index: application to the carotid artery in patients with mitral regurgitation before and after surgery. Heart Vessels 14, 263–271.
50. Ohte, N., Narita, H., Sugawara, M., Niki, K., Okada, T., Harada, A., Hayano, J. & Kimura, G. 2003. Clinical usefulness of carotid arterial wave intensity in assessing left ventricular systolic and early diastolic performance. Heart Vessels 18, 107–111.
51. Parker, K.H. 2009. An introduction to wave intensity analysis. Med Biol Eng Comput 47, 175–188.
52. Parker, K.H. & Jones, C.J. 1990. Forward and backward running waves in the arteries: analysis using the method of characteristics. J Biomech Eng 112, 322–326.
53. Parker, K.H., Jones, C.J., Dawson, J.R. & Gibson, D.G. 1988. What stops the flow of blood from the heart? Heart Vessels 4, 241–245.
54. Quail, M.A., Knight, D.S., Steeden, J.A., Taelman, L., Moledina, S., Taylor, A.M., Segers, P., Coghlan, G.J. & Muthurangu, V. 2015. Noninvasive pulmonary artery wave intensity analysis in pulmonary hypertension. Am J Physiol Heart Circ Physiol 308, H1603–H1611.
55. Ragosta, M. 2008. Textbook of Clinical Hemodynamics. Elsevier Saunders, Philadelphia.
56. Rolandi, M.C., De, S.K., Lumley, M., Lockie, T.P., Clapp, B., Spaan, J.A., Perera, D. & Siebes, M. 2014. Wave speed in human coronary arteries is not influenced by microvascular vasodilation: implications for wave intensity analysis. Basic Res Cardiol 109, 405.
57. Ruggiero, R.M., Bartolome, S. & Torres, F. 2012. Pulmonary hypertension in parenchymal lung disease. Heart Fail Clin 8, 461–474.
58. Schreier, D.A., Forouzan, O., Hacker, T.A., Sheehan, J. & Chesler, N. 2016. Increased red blood cell stiffness increases pulmonary vascular resistance and pulmonary arterial pressure. J Biomech Eng 138, 021012(1)–021012(7).
59. Seferian, A. & Simonneau, G. 2013. Therapies for pulmonary arterial hypertension: where are we today, where do we go tomorrow? Eur Respir Rev 22, 217–226.
60. Segers, P., De, B.J., Devos, D., Rabben, S.I., Gillebert, T.C., Van Bortel, L.M., De, S.J., De, P.A. & Verdonck, P.R. 2006. Aortic reflection coefficients and their association with global indexes of wave reflection in healthy controls and patients with Marfan's syndrome. Am J Physiol Heart Circ Physiol 290, H2385–H2392.
61. Segers, P., Rietzschel, E.R., De Buyzere, M.L., Vermeersch, S.J., De, B.D., Van Bortel, L.M., De, B.G., Gillebert, T.C. & Verdonck, P.R. 2007. Noninvasive (input) impedance, pulse wave velocity, and wave reflection in healthy middle-aged men and women. Hypertension 49, 1248–1255.
62. Segers, P., Swillens, A., Taelman, L. & Vierendeels, J. 2014. Wave reflection leads to over- and underestimation of local wave speed by the PU- and QA-loop methods: theoretical basis and solution to the problem. Physiol Meas 35, 847–861.
63. Sen, S., Escaned, J., Malik, I.S., Mikhail, G.W., Foale, R.A., Mila, R., Tarkin, J., Petraco, R., Broyd, C., Jabbour, R. et al. 2012. Development and validation of a new adenosine-independent index of stenosis severity from coronary wave-intensity analysis: results of the ADVISE (ADenosine Vasodilator Independent Stenosis Evaluation) study. J Am Coll Cardiol 59, 1392–1402.
64. Siebes, M., Kolyva, C., Verhoeff, B.J., Piek, J.J. & Spaan, J.A. 2009. Potential and limitations of wave intensity analysis in coronary arteries. Med Biol Eng Comput 47, 233–239.
65. Singhal, S., Henderson, R., Horsfield, K., Harding, K. & Cumming, G. 1973. Morphometry of the human pulmonary arterial tree. Circ Res 33, 190–197.
66. Smolich, J.J., Mynard, J.P. & Penny, D.J. 2008. Simultaneous pulmonary trunk and pulmonary arterial wave intensity analysis in fetal lambs: evidence for cyclical, midsystolic pulmonary vasoconstriction. Am J Physiol Regul Integr Comp Physiol 294, R1554–R1562.
67. Smolich, J.J., Mynard, J.P. & Penny, D.J. 2009. Dynamic characterization and hemodynamic effects of pulmonary waves in fetal lambs using cardiac extrasystoles and beat-by-beat wave intensity analysis. Am J Physiol Regul Integr Comp Physiol 297, R428–R436.
68. van de Veerdonk, M.C., Kind, T., Marcus, J.T., Mauritz, G.J., Heymans, M.W., Bogaard, H.J., Boonstra, A., Marques, K.M., Westerhof, N. & Vonk-Noordegraaf, A. 2011. Progressive right ventricular dysfunction in patients with pulmonary arterial hypertension responding to therapy. J Am Coll Cardiol 58, 2511–2519.
69. Volcano Corp. 2015. http://www.volcanocorp.com/products/combowire-xt.php#.VZ4vv_l_Okp.
70. Wang, Z. & Chesler, N.C. 2011. Pulmonary vascular wall stiffness: an important contributor to the increased right ventricular afterload with pulmonary hypertension. Pulm Circ 1, 212–223.
71. Westerhof, N., Sipkema, P., van den Bos, G.C. & Elzinga, G. 1972. Forward and backward waves in the arterial system. Cardiovasc Res 6, 648–656.
72. Westerhof, N., Stergiopulos, N. & Noble, M.I.M. 2005. Snapshots of Hemodynamics: An Aid for Clinical Research and Graduate Education. Springer Science + Business Media, New York.
73. Westerhof, B.E., Guelen, I., Westerhof, N., Karemaker, J.M. & Avolio, A. 2006. Quantification of wave reflection in the human aorta from pressure alone: a proof of principle. Hypertension 48, 595–601.
74. Westerhof, B.E., van den Wijngaard, J.P., Murgo, J.P. & Westerhof, N. 2008. Location of a reflection site is elusive: consequences for the calculation of aortic pulse wave velocity. Hypertension 52, 478–483.
75. Westerhof, N., Segers, P. & Westerhof, B.E. 2015. Wave separation, wave intensity, the reservoir-wave concept, and the instantaneous wave-free ratio: presumptions and principles. Hypertension 66, 93–98.
76. Zambanini, A., Cunningham, S.L., Parker, K.H., Khir, A.W., McG Thom, S.A. & Hughes, A.D. 2005. Wave-energy patterns in carotid, brachial, and radial arteries: a noninvasive approach using wave-intensity analysis. Am J Physiol Heart Circ Physiol 289, H270–H276.