Helium inhalation enhances vasodilator effect of inhaled nitric oxide on pulmonary vessels in hypoxic dogs

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 4 49-4, 2001, Pages

  Nie, Masaki ^a   Kobayashi, Hirosuke ^a,c   Sugawara, Motoaki ^b   Tomita, Tomoyuki ^a   Ohara, Kuniyoshi ^a   Yoshimura, Hirokuni ^a  

^a KITASATO UNIVERSITY   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Diffusion; Impedance; Pulmonary hypertension; Wave intensity

Indexed keywords

HELIUM; NITRIC OXIDE; OXYGEN;

ANIMAL MODEL; ARTICLE; BLOOD GAS ANALYSIS; CONTROLLED STUDY; DIFFUSION; DOG; HEMODYNAMICS; IMPEDANCE; LUNG ARTERY PRESSURE; LUNG BLOOD VESSEL; LUNG HEMODYNAMICS; LUNG VASCULAR RESISTANCE; LUNG VASOCONSTRICTION; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; VASODILATATION;

EID: 0035005610     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.4.h1875     Document Type: Article

References (34)

1. Archer SL, Huang JMC, Reeve HL, Hampl V, Tolarova S, Michelakis E, and Weir EK. Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia. Circ Res 78: 431-442, 1996.
2. Barach AL. The use of helium in the treatment of asthma and obstructive lesions in the larynx and trachea. Ann Intern Med 9: 739-765, 1935.
3. Booke M, Bradford DW, Hinder F, Harper D, Brauchle RW, Traber LD, and Traber DL. Effects of inhaled nitric oxide and nebulized prostacyclin on pulmonary vasoconstriction in anesthetized sheep. Crit Care Med 24: 1841-1848, 1996.
4. Brimioulle S, Maggiorini M, Stephanazzi J, Vermeulen F, Lejeune P, and Naeije R. Effects of low flow on pulmonary vascular flow-pressure curves and pulmonary vascular impedance. Cardiovasc Res 42: 183-192, 1999.
5. Chang HK and Farhi LE. On mathematical analysis of gas transport in the lung. Respir Physiol 18: 370-385, 1973.
6. Chang HK and Farhi LE. Ternary diffusion and effective diffusion coefficients in alveolar spaces. Respir Physiol 40: 269-279, 1980.
7. Comroe JH. Physiology of Respiration (2nd ed.). Chicago, IL: Yearbook Medical, 1974.
8. Ewalenko P, Stefanidis C, Holoye A, Brimioulle S, and Naeije R. Pulmonary vascular impedance vs. resistance in hypoxic and hyperoxic dogs: effects of propofol and isoflurane. J Appl Physiol 74: 2188-2193, 1993.
9. Frostell C, Blomqvist H, Hedenstierna G, Lundberg J, and Zapol WM. Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation. Anesthesiology 78: 427-435, 1993.
10. Frostell C, Frataci MD, Wain JC, Jones R, and Zapol WM. Inhaled nitric oxide: a selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation 83: 2038-2047, 1991.
11. Jones CJ, Parker KH, and Sugawara M. Energy wave generation by the left ventricle-influence of contractility and vasomotor tone (Abstract). Br Heart J 66: 78, 1991.
12. Jones CJ and Sugawara M. "Wavefronts" in the aorta-implications for the mechanisms of left ventricular ejection and aortic valve closure. Cardiovasc Res 27: 1902-1905, 1993.
13. Kass JE and Terregino CA. The effect of Heliox in acute severe asthma. A randomized controlled trial. Chest 116: 296-300, 1999.
14. Katayama Y, Higenbottam TW, Cremon G, Akamine S, Demoncheaux EA, Smith AP, and Siddons TE. Minimizing the inhaled dose of NO with breath-by-breath delivery of spikes of concentrated gas. Circulation 98: 2429-2432, 1998.
15. Maggiorini M, Brimioulle S, Canniere DD, Delcroix M, Wauthy P, and Naeije R. Pulmonary vascular impedance response to hypoxia in dogs and minipigs of inhaled nitric oxide. J Appl Physiol 79: 1156-1162, 1995.
16. Manthous CA, Hall JB, Melmed A, Caputo MA, Walter J, Klocksieben JM, Schmidt GA, and Wood LD. Heliox improves pulsus paradoxus and peak expiratory flow in nonintubated patients with severe asthma. Am J Respir Crit Care Med 151: 310-314, 1995.
17. Marrero TR and Mason EA. Gaseous diffusion coefficients. J Phys Chem 1: 111-119, 1972.
18. Milnor WR. Hemodynamics (2nd ed.). Baltimore, MD: Williams and Wilkins, 1989.
19. Olszowka AJ and Farhi LE. A system of digital computer subroutines for blood gas calculation. Respir Physiol 4: 270-280, 1968.
20. Papamoschou D. Theoretical validation of the respiratory benefits of helium oxygen mixtures. Respir Physiol 99: 183-190, 1995.
21. Parker KH, Jones CJ, Dawson JR, and Gibson DG. What stops the flow of blood from the heart? Heart Vessels 4: 241-245, 1988.
22. Parker KH and Jones CJ. Forward and backward running waves in the arteries: analysis using the method of characteristics. J Biomech Eng 112: 322-326, 1990.
23. Pepke-Zaba J, Higenbottam TW, Dinh-Xuan AT, Stone D, and Wallwork J. Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension. Lancet 338: 1173-1174, 1991.
24. Ramsey MW and Sugawara M. Arterial wave intensity and ventriculoarterial interaction. Heart Vessels 12: 128-134, 1997.
25. Reuben SR, Swadling JP, Gersh BJ, and Lee GJ. Impedance and transmission properties of the pulmonary arterial system. Cardiovasc Res 5: 1-9, 1971.
26. Rich GF, Murphy GD Jr, Roos CM, and Johns RA. Inhaled nitric oxide. Selective pulmonary vasodilation in cardiac surgical patients. Anesthesiology 78: 1028-1035, 1993.
27. Rimer S and Gillis CN. Selective pulmonary vasodilation by inhaled nitric oxide is due to hemoglobin inactivation. Circulation 88: 2884-2887, 1993.
28. Roberts JD, Chen TY, Kawai N, Wain J, Dupuy P, Shimouchi A, Bloch K, Polaner D, and Zapol WM. Inhaled nitric oxide reverses pulmonary vasoconstriction in the hypoxic acidotic newborn lamb. Circ Res 72: 246-254, 1993.
29. Roberts JD, Polaner DM, Lang P, and Zapol WM. Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 340: 818-819, 1992.
30. Romand JA, Michael RP, Leonard F, Harvey AZ, and Jack RL Jr. Inhaled nitric oxide partially reverses hypoxic pulmonary vasoconstriction in the dog. J Appl Physiol 76: 1350-1355, 1994.
31. Shirai M, Shimouchi A, Kawaguchi AT, Sunagawa K, and Ninomiya I. Inhaled nitric oxide: diameter response patterns in feline small pulmonary arteries and veins. Am J Physiol Heart Circ Physiol 270: H974-H980, 1996.
32. Takahashi Y, Kobayashi H, Tanaka N, Sato T, Takizawa N, and Tomita T. Nitrosyl hemoglobin in blood of normoxic and hypoxic sheep during nitric oxide inhalation. Am J Physiol Heart Circ Physiol 274: H349-H357, 1998.
33. Williamson DJ, Hayward CR, Wallman LL, Sturgess AD, Penny R, and MacDonald PS. Acute hemodynamic responses to inhaled nitric oxide in patients with limited scleroderma and isolated pulmonary hypertension. Circulation 94: 477-482, 1996.
34. Zapol WM, Rimar S, Gillis N, Marietta M, and Bosken CH. Nitric oxide and the lung. Am J Respir Crit Care Med 149: 1375-1380, 1994.