메뉴 건너뛰기




Volumn 34, Issue , 2016, Pages 14-22

Th17 cells and IL-17 promote the skin and lung inflammation and fibrosis process in a bleomycin-induced murine model of systemic sclerosis

Author keywords

Bleomycin; Fibroblast; Interleukin 17; Mice; Systemic sclerosis; Th17 cells

Indexed keywords

COLLAGEN; INTERLEUKIN 17; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA1; AUTACOID; BLEOMYCIN; IL17A PROTEIN, MOUSE;

EID: 84994422946     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (132)

References (35)
  • 1
    • 84904854851 scopus 로고    scopus 로고
    • Role of endothelial to mesenchymal transition in the pathogenesis of the vascular alterations in systemic sclerosis
    • JIMENEZ SA: Role of endothelial to mesenchymal transition in the pathogenesis of the vascular alterations in systemic sclerosis. ISRN Rheumatol 2013; 835948.
    • (2013) ISRN Rheumatol
    • Jimenez, S.A.1
  • 2
    • 66149120713 scopus 로고    scopus 로고
    • Th17 cells in rheumatoid arthritis and systemic lupus erythematosus
    • PERNIS AB: Th17 cells in rheumatoid arthritis and systemic lupus erythematosus. J Intern Med 2009; 65: 644-52.
    • (2009) J Intern Med , vol.65 , pp. 644-652
    • Pernis, A.B.1
  • 3
    • 69349093225 scopus 로고    scopus 로고
    • Interleukin-17 and type 17 helper T cells
    • MIOSSEC P, KORN T, KUCHROO VK: Interleukin-17 and type 17 helper T cells. N Engl J Med 2009; 361: 888-98.
    • (2009) N Engl J Med , vol.361 , pp. 888-898
    • Miossec, P.1    Korn, T.2    Kuchroo, V.K.3
  • 4
    • 0033758344 scopus 로고    scopus 로고
    • Increased interleukin-17 production in patients with systemic sclerosis
    • KURASAWA K, HIROSE K, SANO H et al.: Increased interleukin-17 production in patients with systemic sclerosis. Arthritis Rheum 2000; 43: 2455-63.
    • (2000) Arthritis Rheum , vol.43 , pp. 2455-2463
    • Kurasawa, K.1    Hirose, K.2    Sano, H.3
  • 5
    • 79955974107 scopus 로고    scopus 로고
    • Alteration of Th17 and Treg cell subpopulations co-exist in patients affected with systemic sclerosis
    • FENOGLIO D, BATTAGLIA F, PARODI A et al.: Alteration of Th17 and Treg cell subpopulations co-exist in patients affected with systemic sclerosis. Clin Immunol 2011; 139: 249-57.
    • (2011) Clin Immunol , vol.139 , pp. 249-257
    • Fenoglio, D.1    Battaglia, F.2    Parodi, A.3
  • 6
    • 84866405411 scopus 로고    scopus 로고
    • Th17 peripheral cells are increased in diffuse cutaneous systemic sclerosis compared with limited illness: a cross-sectional study
    • RODRIGUEZ-REYNA TS, FURUZAWA-CARBALLEDA J, CABIEDES J et al.: Th17 peripheral cells are increased in diffuse cutaneous systemic sclerosis compared with limited illness: a cross-sectional study. Rheumatol Int 2012; 32: 2653-60.
    • (2012) Rheumatol Int , vol.32 , pp. 2653-2660
    • Rodriguez-Reyna, T.S.1    Furuzawa-Carballeda, J.2    Cabiedes, J.3
  • 7
    • 84879446568 scopus 로고    scopus 로고
    • Expression and significance of Th17 cells and related cytokines in a murine model of systemic sclerosis
    • LEI L, ZHONG XN, ZHAO C et al.: Expression and significance of Th17 cells and related cytokines in a murine model of systemic sclerosis. Beijing Da Xue Xue Bao 2012; 44: 259-64.
    • (2012) Beijing Da Xue Xue Bao , vol.44 , pp. 259-264
    • Lei, L.1    Zhong, X.N.2    Zhao, C.3
  • 8
    • 84925301412 scopus 로고    scopus 로고
    • IL-21 Induction of CD4+ T Cell Differentiation into Th17 Cells Contributes to Bleomycin-Induced Fibrosis in Mice
    • LEI L, ZHONG XN, HE ZY et al.: IL-21 Induction of CD4+ T Cell Differentiation into Th17 Cells Contributes to Bleomycin-Induced Fibrosis in Mice. Cell Biol Int 2015; 39: 388-99.
    • (2015) Cell Biol Int , vol.39 , pp. 388-399
    • Lei, L.1    Zhong, X.N.2    He, Z.Y.3
  • 9
    • 84868095046 scopus 로고    scopus 로고
    • Potential roles of interleukin-17A in the development of skin fibrosis in mice
    • OKAMOTO Y, HASEGAWA M, MATSUSHITA T et al.: Potential roles of interleukin-17A in the development of skin fibrosis in mice. Arthritis Rheum 2012; 64: 3726-35.
    • (2012) Arthritis Rheum , vol.64 , pp. 3726-3735
    • Okamoto, Y.1    Hasegawa, M.2    Matsushita, T.3
  • 10
    • 84860330745 scopus 로고    scopus 로고
    • Impaired IL-17 signaling pathway contributes to the increased collagen expression in scleroderma fibroblasts
    • NAKASHIMA T, JINNIN M, YAMANE K et al.: Impaired IL-17 signaling pathway contributes to the increased collagen expression in scleroderma fibroblasts. J Immunol 2012; 188: 3573-83.
    • (2012) J Immunol , vol.188 , pp. 3573-3583
    • Nakashima, T.1    Jinnin, M.2    Yamane, K.3
  • 11
    • 0032706030 scopus 로고    scopus 로고
    • Effect of superoxide dismutase on bleomycin-induced dermal sclerosis: implications for the treatment of systemic sclerosis
    • YAMAMOTO T, TAKAGAWA S, KATAYAMA I et al.: Effect of superoxide dismutase on bleomycin-induced dermal sclerosis: implications for the treatment of systemic sclerosis. J Invest Dermatol 1999; 113: 843-7.
    • (1999) J Invest Dermatol , vol.113 , pp. 843-847
    • Yamamoto, T.1    Takagawa, S.2    Katayama, I.3
  • 12
    • 67449152710 scopus 로고    scopus 로고
    • Induction of autoimmunity in a bleomycin induced murine model of experimental systemic sclerosis: an important role for CD4+ T cells
    • ISHIKAW AH, TAKEDA K, OKAMOTO A et al.: Induction of autoimmunity in a bleomycin induced murine model of experimental systemic sclerosis: an important role for CD4+ T cells. J Invest Dermatol 2009; 129: 1688-95.
    • (2009) J Invest Dermatol , vol.129 , pp. 1688-1695
    • Ishikaw, A.H.1    Takeda, K.2    Okamoto, A.3
  • 13
    • 53349129568 scopus 로고    scopus 로고
    • In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis
    • FINESCHI S, BONGIOVANNI M, DONATI Y et al.: In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis. Am J Respir Cell Mol Biol 2008; 39: 458-65.
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 458-465
    • Fineschi, S.1    Bongiovanni, M.2    Donati, Y.3
  • 14
    • 0023914820 scopus 로고
    • Simple method of estimating severity of pulmonary fibrosis on a numerical scale
    • ASHCROFT T, SIMPSON JM, TIMBERI V: Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J Clin Pathol 1988; 41: 467-70.
    • (1988) J Clin Pathol , vol.41 , pp. 467-470
    • Ashcroft, T.1    Simpson, J.M.2    Timberi, V.3
  • 15
    • 0037087318 scopus 로고    scopus 로고
    • Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation
    • ZHANG Y, McCORMICK LL, DESAI SR et al.: Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation. J Immunol 2002; 168: 3088-98.
    • (2002) J Immunol , vol.168 , pp. 3088-3098
    • Zhang, Y.1    Mccormick, L.L.2    Desai, S.R.3
  • 16
    • 23144466310 scopus 로고    scopus 로고
    • Time course of cigarette smoke-induced pulmonary inflammation in mice
    • D'HULST AI, VERMAELEN KY, BRUSSELLE GG et al.: Time course of cigarette smoke-induced pulmonary inflammation in mice. Eur Respir J 2005; 26: 204-13.
    • (2005) Eur Respir J , vol.26 , pp. 204-213
    • D'hulst, A.I.1    Vermaelen, K.Y.2    Brusselle, G.G.3
  • 17
    • 33751502815 scopus 로고    scopus 로고
    • Correlation of the expression levels of BLyS and its receptors mRNA in patients with systemic lupus erythematosus
    • JU S, ZHANG D, WANG Y et al.: Correlation of the expression levels of BLyS and its receptors mRNA in patients with systemic lupus erythematosus. Clin Biochem 2006; 39: 1131-7.
    • (2006) Clin Biochem , vol.39 , pp. 1131-1137
    • Ju, S.1    Zhang, D.2    Wang, Y.3
  • 18
    • 84892163120 scopus 로고    scopus 로고
    • Increased frequency of Th17 cells in systemic sclerosis is related to disease activity and collagen overproduction
    • YANG X, YANG J, XING X et al.: Increased frequency of Th17 cells in systemic sclerosis is related to disease activity and collagen overproduction. Arthritis Res Ther 2014; 16: R4.
    • (2014) Arthritis Res Ther , vol.16 , pp. R4
    • Yang, X.1    Yang, J.2    Xing, X.3
  • 19
    • 80053911955 scopus 로고    scopus 로고
    • Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes insystemic sclerosis: association with interstitial lung disease
    • TRUCHETET ME, BREMBILLA NC, MONTANARI E et al.: Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes insystemic sclerosis: association with interstitial lung disease. Arthritis Res Ther 2011; 13: R166.
    • (2011) Arthritis Res Ther , vol.13 , pp. R166
    • Truchetet, M.E.1    Brembilla, N.C.2    Montanari, E.3
  • 20
    • 84885063002 scopus 로고    scopus 로고
    • Th17 cells favor inflammatory responses while inhibiting type I collagen deposition by dermal fibroblasts: differential effects in healthy and systemic sclerosis fibroblasts
    • BREMBILLA NC, MONTANARI E, TRUCHETET ME et al.: Th17 cells favor inflammatory responses while inhibiting type I collagen deposition by dermal fibroblasts: differential effects in healthy and systemic sclerosis fibroblasts. Arthritis Res Ther 2013; 15: R151.
    • (2013) Arthritis Res Ther , vol.15 , pp. R151
    • Brembilla, N.C.1    Montanari, E.2    Truchetet, M.E.3
  • 21
    • 84873721826 scopus 로고    scopus 로고
    • Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement
    • TRUCHETET ME, BREMBILLA NC, MONTANARI E et al.: Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement. Arthritis Rheum 2013; 65: 1347-56.
    • (2013) Arthritis Rheum , vol.65 , pp. 1347-1356
    • Truchetet, M.E.1    Brembilla, N.C.2    Montanari, E.3
  • 22
    • 42649134787 scopus 로고    scopus 로고
    • Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease?
    • MURATA M, FUJIMOTO M, MATSUSHITA T et al.: Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease? J Dermatol Sci 2008; 50: 240-2.
    • (2008) J Dermatol Sci , vol.50 , pp. 240-242
    • Murata, M.1    Fujimoto, M.2    Matsushita, T.3
  • 23
    • 79955618079 scopus 로고    scopus 로고
    • Altered T-cell and regulatory cell repertoire in patients with diffuse cutaneous systemic sclerosis
    • PAPP G, HORATH IF, BARATH S et al.: Altered T-cell and regulatory cell repertoire in patients with diffuse cutaneous systemic sclerosis. Scand J Rheumatol 2011; 40: 205-10.
    • (2011) Scand J Rheumatol , vol.40 , pp. 205-210
    • Papp, G.1    Horath, I.F.2    Barath, S.3
  • 24
    • 77956899738 scopus 로고    scopus 로고
    • Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model
    • YOSHIZAKI A, YANABA K, IWATA Y et al.: Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. J Immunol 2010; 185: 2502-15.
    • (2010) J Immunol , vol.185 , pp. 2502-2515
    • Yoshizaki, A.1    Yanaba, K.2    Iwata, Y.3
  • 25
    • 77949516122 scopus 로고    scopus 로고
    • Bleomycin and IL-1-mediated pulmonary fibrosis is IL-17A dependent
    • WILSON MS, MADALA SK, RAMALINGAM TR et al.: Bleomycin and IL-1-mediated pulmonary fibrosis is IL-17A dependent. J Exp Med 2010; 207: 535-52.
    • (2010) J Exp Med , vol.207 , pp. 535-552
    • Wilson, M.S.1    Madala, S.K.2    Ramalingam, T.R.3
  • 26
    • 80053070208 scopus 로고    scopus 로고
    • Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-1-dependent and-independent mechanisms
    • MI S, LI Z, YANG HZ et al.: Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-1-dependent and-independent mechanisms. J Immunol 2011; 187: 3003-14.
    • (2011) J Immunol , vol.187 , pp. 3003-3014
    • Mi, S.1    Li, Z.2    Yang, H.Z.3
  • 27
    • 80051684471 scopus 로고    scopus 로고
    • IL-1 and IL-23 mediate early IL-17A production in pulmo nary inflammation leading to late fibrosis
    • GASSE P, RITEAU N, VACHER R et al.: IL-1 and IL-23 mediate early IL-17A production in pulmo nary inflammation leading to late fibrosis. PLoS One 2011; 6: e23185.
    • (2011) PLoS One , vol.6
    • Gasse, P.1    Riteau, N.2    Vacher, R.3
  • 28
    • 84925868729 scopus 로고    scopus 로고
    • Systemic sclerosis: a critical digest of the recent literature
    • BARSOTTI S, BELLANDO RANDONE S et al.: Systemic sclerosis: a critical digest of the recent literature. Clin Exp Rheumatol 2014; 32: 194-205.
    • (2014) Clin Exp Rheumatol , vol.32 , pp. 194-205
    • Barsotti, S.1    Bellando Randone, S.2
  • 29
    • 37349113805 scopus 로고    scopus 로고
    • Autocrine TGF-beta signaling in the pathogenesis of systemic sclerosis
    • IHN H: Autocrine TGF-beta signaling in the pathogenesis of systemic sclerosis. J Dermatol Sci 2008; 49: 103-13.
    • (2008) J Dermatol Sci , vol.49 , pp. 103-113
    • Ihn, H.1
  • 30
    • 81555209757 scopus 로고    scopus 로고
    • The many faces of interleukin-6: the role of IL-6 in inflammation, vasculopathy, and fibrosis in systemic sclerosis
    • BARNES TC, ANDERSON ME, MOOTS RJ et al.: The many faces of interleukin-6: the role of IL-6 in inflammation, vasculopathy, and fibrosis in systemic sclerosis. Int J Rheumatol 2011; 2011: 721608.
    • (2011) Int J Rheumatol , vol.2011
    • Barnes, T.C.1    Anderson, M.E.2    Moots, R.J.3
  • 31
    • 0034833339 scopus 로고    scopus 로고
    • IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
    • MOLET S, HAMID Q, DAVOINE F et al.: IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol 2001; 108: 430-38.
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 430-438
    • Molet, S.1    Hamid, Q.2    Davoine, F.3
  • 32
    • 0026601232 scopus 로고
    • Interleukin-1, interleukin-2, interleukin-4, interleukin-6, tumor necrosis factor a, and interferon-g levels in sera from patients with scleroderma
    • NEEDLEMAN BW, WIGLEY FM, STAIR RW: Interleukin-1, interleukin-2, interleukin-4, interleukin-6, tumor necrosis factor a, and interferon-g levels in sera from patients with scleroderma. Arthritis Rheum 1992; 35: 67-72.
    • (1992) Arthritis Rheum , vol.35 , pp. 67-72
    • Needleman, B.W.1    Wigley, F.M.2    Stair, R.W.3
  • 33
    • 0038798085 scopus 로고    scopus 로고
    • Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis
    • NAKAHARA H, SONG J, SUGIMOTO M et al.: Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis. Arthritis Rheum 2003; 48: 1521-9.
    • (2003) Arthritis Rheum , vol.48 , pp. 1521-1529
    • Nakahara, H.1    Song, J.2    Sugimoto, M.3
  • 34
    • 78049421175 scopus 로고    scopus 로고
    • The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab
    • SHIMA Y, KUWAHARA Y, MUROTA H et al.: The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab. Rheumatology (Oxford) 2010; 49: 2408-12.
    • (2010) Rheumatology (Oxford) , vol.49 , pp. 2408-2412
    • Shima, Y.1    Kuwahara, Y.2    Murota, H.3
  • 35
    • 84877142755 scopus 로고    scopus 로고
    • Transdifferentiation of fibroblasts into myofibroblasts in the skin lesion of systemic sclerosis: role of transforming growth factor β1 and its signal transduction
    • LIU T, HU XD: Transdifferentiation of fibroblasts into myofibroblasts in the skin lesion of systemic sclerosis: role of transforming growth factor β1 and its signal transduction. Nan Fang Yi Ke Da Xue Xue Bao 2011; 31: 1840-5.
    • (2011) Nan Fang Yi Ke Da Xue Xue Bao , vol.31 , pp. 1840-1845
    • Liu, T.1    Hu, X.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.