Structural insights into the transport mechanism of the human sodium-dependent lysophosphatidylcholine transporter MFSD2A

Journal of Biological Chemistry

Volumn 291, Issue 18, 2016, Pages 9383-9394

  Quek, Debra Q Y ^a   Nguyen, Long N ^b   Fan, Hao ^a,c   Silver, David L ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c BIOINFORMATICS INSTITUTE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; FATTY ACIDS; HYDROCARBON REFINING; HYDROPHOBICITY;

BIOCHEMICAL ANALYSIS; BLOOD-BRAIN BARRIER; LONG CHAIN FATTY ACID; LYSOPHOSPHATIDYL-CHOLINE; MAJOR FACILITATOR SUPERFAMILY; STRUCTURAL INSIGHTS; TRANSMEMBRANE HELICES; TRANSPORT MECHANISM;

BINDING SITES;

BACTERIAL PROTEIN; CARRIER PROTEIN; LACY PROTEIN; MAJOR FACILITATOR SUPERFAMILY DOMAIN CONTAINING 2A PROTEIN; MELB PROTEIN; MFSD2A PROTEIN; SODIUM DEPENDENT LYSOPHOSPHATIDYLCHOLINE TRANSPORTER; UNCLASSIFIED DRUG; LYSOPHOSPHATIDYLCHOLINE; MFSD2A PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; BLOOD BRAIN BARRIER; CRYSTAL STRUCTURE; ENDOTHELIUM; ESCHERICHIA COLI; HUMAN; HYDROPHOBICITY; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; MOLECULAR DOCKING; MUTAGENESIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SEQUENCE HOMOLOGY; ACTIVE TRANSPORT; ANIMAL; CELL MEMBRANE; CHEMISTRY; METABOLISM; MOLECULAR MODEL; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CELL MEMBRANE; HUMANS; LYSOPHOSPHATIDYLCHOLINES; MICE; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; TUMOR SUPPRESSOR PROTEINS;

EID: 84994378237     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.721035     Document Type: Article

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