The melibiose transporter of Escherichia coli: Critical contribution of Lys-377 to the structural organization of the interacting substrate binding sites

Journal of Biological Chemistry

Volumn 290, Issue 26, 2015, Pages 16261-16271

  Fuerst, Oliver ^a   Lin, Yibin ^a   Granell, Meritxell ^a,d   Leblanc, Gérard ^b   Padrós, Esteve ^a   Lórenz Fonfría, Víctor A ^a,c   Cladera, Josep ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHAINS; ESCHERICHIA COLI; LIGANDS; MOLECULAR DYNAMICS; SPECTROSCOPIC ANALYSIS;

FOURIER TRANSFORM INFRARED DIFFERENCE SPECTROSCOPY; FUNCTIONAL MECHANISMS; INTRINSIC FLUORESCENCE; MOLECULAR DYNAMICS SIMULATIONS; SPATIAL ORGANIZATION; SPECTROSCOPIC MEASUREMENTS; STRUCTURAL ORGANIZATION; SUBSTRATE-BINDING SITES;

BINDING SITES;

ARGININE; ASPARTIC ACID; CYSTEINE; ISOLEUCINE; LYSINE; MELIBIOSE; SODIUM; SUGAR; VALINE; COTRANSPORTER; MELIBIOSE PERMEASE;

AMINO ACID TRANSPORT; ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL BINDING; CONTROLLED STUDY; ESCHERICHIA COLI; MOLECULAR DYNAMICS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; KINETICS; METABOLISM; PROTEIN MOTIF;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; ESCHERICHIA COLI; ISOLEUCINE; KINETICS; LYSINE; MELIBIOSE; MOLECULAR DYNAMICS SIMULATION; SODIUM; SYMPORTERS;

EID: 84941287084     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.642678     Document Type: Article

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