Neuraminidase A-exposed galactose promotes Streptococcus pneumoniae biofilm formation during colonization

Infection and Immunity

Volumn 84, Issue 10, 2016, Pages 2922-2932

  Blanchette, Krystle A ^a   Shenoy, Anukul T ^a,b   Milner, Jeffrey ^b   Gilley, Ryan P ^a   McClure, Erin ^c   Hinojosa, Cecilia A ^a   Kumar, Nikhil ^c   Daugherty, Sean C ^c   Tallon, Luke J ^c   Ott, Sandra ^c   King, Samantha J ^d,e   Ferreira, Daniela M ^f   Gordon, Stephen B ^f   Tettelin, Hervé ^c   Orihuela, Carlos J ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^e OHIO STATE UNIVERSITY   (United States)

^f LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL PHOSPHATE; BETA GALACTOSIDASE; CARBON; FRUCTOSE; GALACTOSE; GLUCOSE; GLYCOPROTEIN; LACTOSE; NEURAMINIDASE A; PHOSPHATE; PYRUVATE OXIDASE; PYRUVIC ACID; SIALIC ACID; SIALIDASE; SUCROSE; TRANSCRIPTOME; UNCLASSIFIED DRUG; CARBOHYDRATE; N ACETYLNEURAMINIC ACID;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BGAA GENE; BIOFILM; CARBOHYDRATE METABOLISM; CARBON CATABOLITE REPRESSION; CARBON SOURCE; CATABOLITE REPRESSION; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIUM CELL; FATTY ACID SYNTHESIS; FEMALE; GENE MUTATION; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NANA GENE; NASAL LAVAGE FLUID; NASOPHARYNX; NONHUMAN; NORMAL HUMAN; PHENOTYPE; PLANKTON; PRIORITY JOURNAL; RNA SEQUENCE; SERUM; STREPTOCOCCUS PNEUMONIAE; ANALYSIS OF VARIANCE; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGY; NOSE SEPTUM; PHYSIOLOGY; PNEUMOCOCCAL INFECTION;

ANALYSIS OF VARIANCE; ANIMALS; BETA-GALACTOSIDASE; BIOFILMS; CARBOHYDRATE METABOLISM; CARBOHYDRATES; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FEMALE; GALACTOSE; HUMANS; MICE; MICE, INBRED BALB C; N-ACETYLNEURAMINIC ACID; NASAL LAVAGE FLUID; NASAL SEPTUM; NASOPHARYNX; NEURAMINIDASE; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE;

EID: 84994365019     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00277-16     Document Type: Article

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