-
1
-
-
84918815964
-
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
-
COI: 1:CAS:528:DC%2BC2cXitVyktbzI, PID: 25220842
-
Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136(5):E359–E86.
-
(2015)
Int J Cancer
, vol.136
, Issue.5
, pp. E359-E386
-
-
Ferlay, J.1
Soerjomataram, I.2
Dikshit, R.3
Eser, S.4
Mathers, C.5
Rebelo, M.6
-
2
-
-
9144225349
-
Occupation and bladder cancer among men in Western Europe
-
PID: 14750529
-
Kogevinas M, Mannetje AT, Cordier S, Ranft U, González CA, Vineis P, et al. Occupation and bladder cancer among men in Western Europe. Cancer Causes Control. 2003;14(10):907–14.
-
(2003)
Cancer Causes Control
, vol.14
, Issue.10
, pp. 907-914
-
-
Kogevinas, M.1
Mannetje, A.T.2
Cordier, S.3
Ranft, U.4
González, C.A.5
Vineis, P.6
-
3
-
-
75849120603
-
Histologic variants of urothelial bladder cancer and nonurothelial histology in bladder cancer
-
Chalasani V, Chin JL, Izawa JI. Histologic variants of urothelial bladder cancer and nonurothelial histology in bladder cancer. Can Urol Assoc J. 2009;3(6-S4):193–8.
-
(2009)
Can Urol Assoc J
, vol.3
, Issue.6-S4
, pp. 193-198
-
-
Chalasani, V.1
Chin, J.L.2
Izawa, J.I.3
-
4
-
-
84864656353
-
Accelerated methotrexate, vinblastine, doxorubicin, and cisplatin (AMVAC) as neoadjuvant chemotherapy for patients with muscle‐invasive transitional cell carcinoma of the bladder
-
COI: 1:CAS:528:DC%2BC38XhtFaksr7K, PID: 22614698
-
Blick C, Hall P, Pwint T, Al‐Terkait F, Crew J, Powles T, et al. Accelerated methotrexate, vinblastine, doxorubicin, and cisplatin (AMVAC) as neoadjuvant chemotherapy for patients with muscle‐invasive transitional cell carcinoma of the bladder. Cancer. 2012;118(16):3920–7.
-
(2012)
Cancer
, vol.118
, Issue.16
, pp. 3920-3927
-
-
Blick, C.1
Hall, P.2
Pwint, T.3
Al‐Terkait, F.4
Crew, J.5
Powles, T.6
-
5
-
-
0035873915
-
Randomized phase III trial of high–dose-intensity methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) chemotherapy and recombinant human granulocyte colony-stimulating factor versus classic MVAC in advanced urothelial tract tumors: European Organization for Research and Treatment of Cancer Protocol No. 30924
-
COI: 1:CAS:528:DC%2BD3MXkt1Omu78%3D, PID: 11352955
-
Sternberg C, De Mulder P, Schornagel J, Theodore C, Fossa S, Van Oosterom A, et al. Randomized phase III trial of high–dose-intensity methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) chemotherapy and recombinant human granulocyte colony-stimulating factor versus classic MVAC in advanced urothelial tract tumors: European Organization for Research and Treatment of Cancer Protocol No. 30924. J Clin Oncol. 2001;19(10):2638–46.
-
(2001)
J Clin Oncol
, vol.19
, Issue.10
, pp. 2638-2646
-
-
Sternberg, C.1
De Mulder, P.2
Schornagel, J.3
Theodore, C.4
Fossa, S.5
Van Oosterom, A.6
-
6
-
-
23044501890
-
Long-term survival results of a randomized trial comparing gemcitabine plus cisplatin, with methotrexate, vinblastine, doxorubicin, plus cisplatin in patients with bladder cancer
-
PID: 16034041
-
von der Maase H, Sengelov L, Roberts JT, Ricci S, Dogliotti L, Oliver T, et al. Long-term survival results of a randomized trial comparing gemcitabine plus cisplatin, with methotrexate, vinblastine, doxorubicin, plus cisplatin in patients with bladder cancer. J Clin Oncol. 2005;23(21):4602–8.
-
(2005)
J Clin Oncol
, vol.23
, Issue.21
, pp. 4602-4608
-
-
von der Maase, H.1
Sengelov, L.2
Roberts, J.T.3
Ricci, S.4
Dogliotti, L.5
Oliver, T.6
-
7
-
-
0026625220
-
A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study
-
PID: 1607913
-
Loehrer P, Einhorn LH, Elson PJ, Crawford ED, Kuebler P, Tannock I, et al. A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study. J Clin Oncol. 1992;10(7):1066–73.
-
(1992)
J Clin Oncol
, vol.10
, Issue.7
, pp. 1066-1073
-
-
Loehrer, P.1
Einhorn, L.H.2
Elson, P.J.3
Crawford, E.D.4
Kuebler, P.5
Tannock, I.6
-
8
-
-
84863897662
-
Randomized phase III study comparing paclitaxel/cisplatin/gemcitabine and gemcitabine/cisplatin in patients with locally advanced or metastatic urothelial cancer without prior systemic therapy: EORTC Intergroup Study 30987
-
COI: 1:CAS:528:DC%2BC38XntVOqtb0%3D, PID: 22370319
-
Bellmunt J, von der Maase H, Mead GM, Skoneczna I, De Santis M, Daugaard G, et al. Randomized phase III study comparing paclitaxel/cisplatin/gemcitabine and gemcitabine/cisplatin in patients with locally advanced or metastatic urothelial cancer without prior systemic therapy: EORTC Intergroup Study 30987. J Clin Oncol. 2012;30(10):1107–13.
-
(2012)
J Clin Oncol
, vol.30
, Issue.10
, pp. 1107-1113
-
-
Bellmunt, J.1
von der Maase, H.2
Mead, G.M.3
Skoneczna, I.4
De Santis, M.5
Daugaard, G.6
-
9
-
-
34249083806
-
Gemcitabine plus cisplatin versus gemcitabine plus carboplatin as first-line chemotherapy in advanced transitional cell carcinoma of the urothelium: results of a randomized phase 2 trial
-
COI: 1:CAS:528:DC%2BD2sXotFyltrg%3D, PID: 17207911
-
Dogliotti L, Cartenì G, Siena S, Bertetto O, Martoni A, Bono A, et al. Gemcitabine plus cisplatin versus gemcitabine plus carboplatin as first-line chemotherapy in advanced transitional cell carcinoma of the urothelium: results of a randomized phase 2 trial. Eur Urol. 2007;52(1):134–41.
-
(2007)
Eur Urol
, vol.52
, Issue.1
, pp. 134-141
-
-
Dogliotti, L.1
Cartenì, G.2
Siena, S.3
Bertetto, O.4
Martoni, A.5
Bono, A.6
-
10
-
-
0037819331
-
Phase I and pharmacokinetic study of the new vinca alkaloid vinflunine administered as a 10-min infusion every 3 weeks in patients with advanced solid tumours
-
COI: 1:STN:280:DC%2BD3s7jsVSitg%3D%3D, PID: 12649112
-
Bennouna J, Fumoleau P, Armand J-P, Raymond E, Campone M, Delgado F-M, et al. Phase I and pharmacokinetic study of the new vinca alkaloid vinflunine administered as a 10-min infusion every 3 weeks in patients with advanced solid tumours. Ann Oncol. 2003;14(4):630–7.
-
(2003)
Ann Oncol
, vol.14
, Issue.4
, pp. 630-637
-
-
Bennouna, J.1
Fumoleau, P.2
Armand, J.-P.3
Raymond, E.4
Campone, M.5
Delgado, F.-M.6
-
11
-
-
33646681175
-
Phase I study of vinflunine administered as a 10-minute infusion on days 1 and 8 every 3 weeks
-
COI: 1:CAS:528:DC%2BD28XktlWlsL8%3D, PID: 16211365
-
Johnson P, Geldart T, Fumoleau P, Pinel M-C, Nguyen L, Judson I. Phase I study of vinflunine administered as a 10-minute infusion on days 1 and 8 every 3 weeks. Invest New Drugs. 2006;24(3):223–31.
-
(2006)
Invest New Drugs
, vol.24
, Issue.3
, pp. 223-231
-
-
Johnson, P.1
Geldart, T.2
Fumoleau, P.3
Pinel, M.-C.4
Nguyen, L.5
Judson, I.6
-
12
-
-
33845978361
-
CYP3A4 mediated in vitro metabolism of vinflunine in human liver microsomes
-
PID: 17184591
-
Zhao X-P, Zhong J, Liu X-Q, Wang G-J. CYP3A4 mediated in vitro metabolism of vinflunine in human liver microsomes. Acta Pharmacol Sin. 2007;28(1):118–24.
-
(2007)
Acta Pharmacol Sin
, vol.28
, Issue.1
, pp. 118-124
-
-
Zhao, X.-P.1
Zhong, J.2
Liu, X.-Q.3
Wang, G.-J.4
-
13
-
-
84994202452
-
-
Focan C, Van Heugen J, Kreutz F, Leroy I, De Graeve J, Blanchot G et al., editors. Vinflunine metabolism and disposition in cancer patients. Proc Am Soc Clin Oncol; 2002. p. 124a (Abstract 495)
-
Focan C, Van Heugen J, Kreutz F, Leroy I, De Graeve J, Blanchot G et al., editors. Vinflunine metabolism and disposition in cancer patients. Proc Am Soc Clin Oncol; 2002. p. 124a (Abstract 495).
-
-
-
-
14
-
-
82555170343
-
Vinflunine: a new vision that may translate into antiangiogenic and antimetastatic activity
-
COI: 1:CAS:528:DC%2BC3MXhsFarsL7I, PID: 22027536
-
Aparicio LMA, Pulido EG, Gallego GA. Vinflunine: a new vision that may translate into antiangiogenic and antimetastatic activity. Anticancer Drugs. 2012;23(1):1–11.
-
(2012)
Anticancer Drugs
, vol.23
, Issue.1
, pp. 1-11
-
-
Aparicio, L.M.A.1
Pulido, E.G.2
Gallego, G.A.3
-
15
-
-
84903862328
-
Role of the microtubule-targeting drug vinflunine on cell-cell adhesions in bladder epithelial tumour cells
-
PID: 25012153
-
Aparicio LA, Castosa R, Haz-Conde M, Rodríguez M, Blanco M, Valladares M, et al. Role of the microtubule-targeting drug vinflunine on cell-cell adhesions in bladder epithelial tumour cells. BMC Cancer. 2014;14(1):507.
-
(2014)
BMC Cancer
, vol.14
, Issue.1
, pp. 507
-
-
Aparicio, L.A.1
Castosa, R.2
Haz-Conde, M.3
Rodríguez, M.4
Blanco, M.5
Valladares, M.6
-
16
-
-
0032031453
-
Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated Vinca alkaloid
-
COI: 1:CAS:528:DyaK1cXnvVantQ%3D%3D, PID: 9515574
-
Kruczynski A, Barret J-M, Etiévant C, Colpaert F, Fahy J, Hill BT. Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated Vinca alkaloid. Biochem Pharmacol. 1998;55(5):635–48.
-
(1998)
Biochem Pharmacol
, vol.55
, Issue.5
, pp. 635-648
-
-
Kruczynski, A.1
Barret, J.-M.2
Etiévant, C.3
Colpaert, F.4
Fahy, J.5
Hill, B.T.6
-
17
-
-
0034665163
-
Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules
-
COI: 1:CAS:528:DC%2BD3cXntVamtLg%3D, PID: 11016627
-
Ngan VK, Bellman K, Panda D, Hill BT, Jordan MA, Wilson L. Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules. Cancer Res. 2000;60(18):5045–51.
-
(2000)
Cancer Res
, vol.60
, Issue.18
, pp. 5045-5051
-
-
Ngan, V.K.1
Bellman, K.2
Panda, D.3
Hill, B.T.4
Jordan, M.A.5
Wilson, L.6
-
18
-
-
33750075041
-
Anti-angiogenic, vascular-disrupting and anti-metastatic activities of vinflunine, the latest vinca alkaloid in clinical development
-
COI: 1:CAS:528:DC%2BD28XhtFSrtb3L, PID: 16973349
-
Kruczynski A, Poli M, Dossi R, Chazottes E, Berrichon G, Ricome C, et al. Anti-angiogenic, vascular-disrupting and anti-metastatic activities of vinflunine, the latest vinca alkaloid in clinical development. Eur J Cancer. 2006;42(16):2821–32.
-
(2006)
Eur J Cancer
, vol.42
, Issue.16
, pp. 2821-2832
-
-
Kruczynski, A.1
Poli, M.2
Dossi, R.3
Chazottes, E.4
Berrichon, G.5
Ricome, C.6
-
19
-
-
0035150786
-
Anti-vascular effects of vinflunine in the MAC 15A transplantable adenocarcinoma model
-
COI: 1:CAS:528:DC%2BD3MXht1WgsrY%3D, PID: 11161390
-
Holwell S, Hill B, Bibby M. Anti-vascular effects of vinflunine in the MAC 15A transplantable adenocarcinoma model. Br J Cancer. 2001;84(2):290.
-
(2001)
Br J Cancer
, vol.84
, Issue.2
, pp. 290
-
-
Holwell, S.1
Hill, B.2
Bibby, M.3
-
20
-
-
0031005761
-
Phase II trial of docetaxel in patients with advanced or metastatic transitional-cell carcinoma
-
COI: 1:CAS:528:DyaK2sXjsVClsLw%3D, PID: 9164195
-
McCaffrey JA, Hilton S, Mazumdar M, Sadan S, Kelly WK, Scher HI, et al. Phase II trial of docetaxel in patients with advanced or metastatic transitional-cell carcinoma. J Clin Oncol. 1997;15(5):1853–7.
-
(1997)
J Clin Oncol
, vol.15
, Issue.5
, pp. 1853-1857
-
-
McCaffrey, J.A.1
Hilton, S.2
Mazumdar, M.3
Sadan, S.4
Kelly, W.K.5
Scher, H.I.6
-
21
-
-
0031052826
-
Phase II study of paclitaxel in pretreated patients with locally advanced/metastatic cancer of the bladder and ureter
-
COI: 1:CAS:528:DyaK2sXhslWitrk%3D, PID: 9052419
-
Papamichael D, Gallagher C, Oliver R, Johnson P, Waxman J. Phase II study of paclitaxel in pretreated patients with locally advanced/metastatic cancer of the bladder and ureter. Br J Cancer. 1997;75(4):606.
-
(1997)
Br J Cancer
, vol.75
, Issue.4
, pp. 606
-
-
Papamichael, D.1
Gallagher, C.2
Oliver, R.3
Johnson, P.4
Waxman, J.5
-
22
-
-
0037083580
-
Phase II trial of weekly paclitaxel in patients with previously treated advanced urothelial cancer
-
COI: 1:CAS:528:DC%2BD38XitFOqtb0%3D, PID: 11844814
-
Vaughn DJ, Broome CM, Hussain M, Gutheil JC, Markowitz AB. Phase II trial of weekly paclitaxel in patients with previously treated advanced urothelial cancer. J Clin Oncol. 2002;20(4):937–40.
-
(2002)
J Clin Oncol
, vol.20
, Issue.4
, pp. 937-940
-
-
Vaughn, D.J.1
Broome, C.M.2
Hussain, M.3
Gutheil, J.C.4
Markowitz, A.B.5
-
23
-
-
33746851717
-
Phase II study of pemetrexed for second-line treatment of transitional cell cancer of the urothelium
-
COI: 1:CAS:528:DC%2BD28Xot1KisLs%3D, PID: 16849761
-
Sweeney CJ, Roth BJ, Kabbinavar FF, Vaughn DJ, Arning M, Curiel RE, et al. Phase II study of pemetrexed for second-line treatment of transitional cell cancer of the urothelium. J Clin Oncol. 2006;24(21):3451–7.
-
(2006)
J Clin Oncol
, vol.24
, Issue.21
, pp. 3451-3457
-
-
Sweeney, C.J.1
Roth, B.J.2
Kabbinavar, F.F.3
Vaughn, D.J.4
Arning, M.5
Curiel, R.E.6
-
24
-
-
34248641378
-
Phase II trial of pemetrexed as second-line therapy in patients with metastatic urothelial carcinoma
-
COI: 1:CAS:528:DC%2BD2sXltlartrY%3D, PID: 17146733
-
Galsky MD, Mironov S, Iasonos A, Scattergood J, Boyle MG, Bajorin DF. Phase II trial of pemetrexed as second-line therapy in patients with metastatic urothelial carcinoma. Invest New Drugs. 2007;25(3):265–70.
-
(2007)
Invest New Drugs
, vol.25
, Issue.3
, pp. 265-270
-
-
Galsky, M.D.1
Mironov, S.2
Iasonos, A.3
Scattergood, J.4
Boyle, M.G.5
Bajorin, D.F.6
-
25
-
-
77956191168
-
Second-line systemic therapy and emerging drugs for metastatic transitional-cell carcinoma of the urothelium
-
COI: 1:CAS:528:DC%2BC3cXhtFWqsrzN, PID: 20537950
-
Sonpavde G, Sternberg CN, Rosenberg JE, Hahn NM, Galsky MD, Vogelzang NJ. Second-line systemic therapy and emerging drugs for metastatic transitional-cell carcinoma of the urothelium. Lancet Oncol. 2010;11(9):861–70.
-
(2010)
Lancet Oncol
, vol.11
, Issue.9
, pp. 861-870
-
-
Sonpavde, G.1
Sternberg, C.N.2
Rosenberg, J.E.3
Hahn, N.M.4
Galsky, M.D.5
Vogelzang, N.J.6
-
26
-
-
33646844469
-
A phase II study of vinflunine in bladder cancer patients progressing after first-line platinum-containing regimen
-
COI: 1:CAS:528:DC%2BD28XksFKnurw%3D, PID: 16622447
-
Culine S, Theodore C, De Santis M, Bui B, Demkow T, Lorenz J, et al. A phase II study of vinflunine in bladder cancer patients progressing after first-line platinum-containing regimen. Br J Cancer. 2006;94(10):1395–401.
-
(2006)
Br J Cancer
, vol.94
, Issue.10
, pp. 1395-1401
-
-
Culine, S.1
Theodore, C.2
De Santis, M.3
Bui, B.4
Demkow, T.5
Lorenz, J.6
-
27
-
-
70149110433
-
Vinflunine in platinum‐pretreated patients with locally advanced or metastatic urothelial carcinoma
-
COI: 1:CAS:528:DC%2BD1MXhtF2ktbnE, PID: 19536904
-
Vaughn DJ, Srinivas S, Stadler WM, Pili R, Petrylak D, Sternberg CN, et al. Vinflunine in platinum‐pretreated patients with locally advanced or metastatic urothelial carcinoma. Cancer. 2009;115(18):4110–7.
-
(2009)
Cancer
, vol.115
, Issue.18
, pp. 4110-4117
-
-
Vaughn, D.J.1
Srinivas, S.2
Stadler, W.M.3
Pili, R.4
Petrylak, D.5
Sternberg, C.N.6
-
28
-
-
75149128685
-
Phase III trial of vinflunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract
-
COI: 1:CAS:528:DC%2BD1MXhtlCnsrfI, PID: 19687335
-
Bellmunt J, Théodore C, Demkov T, Komyakov B, Sengelov L, Daugaard G, et al. Phase III trial of vinflunine plus best supportive care compared with best supportive care alone after a platinum-containing regimen in patients with advanced transitional cell carcinoma of the urothelial tract. J Clin Oncol. 2009;27(27):4454–61.
-
(2009)
J Clin Oncol
, vol.27
, Issue.27
, pp. 4454-4461
-
-
Bellmunt, J.1
Théodore, C.2
Demkov, T.3
Komyakov, B.4
Sengelov, L.5
Daugaard, G.6
-
29
-
-
0032887956
-
Long-term survival in metastatic transitional-cell carcinoma and prognostic factors predicting outcome of therapy
-
COI: 1:STN:280:DyaK1MvjvVWrtw%3D%3D, PID: 10506615
-
Bajorin DF, Dodd PM, Mazumdar M, Fazzari M, McCaffrey JA, Scher HI, et al. Long-term survival in metastatic transitional-cell carcinoma and prognostic factors predicting outcome of therapy. J Clin Oncol. 1999;17(10):3173–81.
-
(1999)
J Clin Oncol
, vol.17
, Issue.10
, pp. 3173-3181
-
-
Bajorin, D.F.1
Dodd, P.M.2
Mazumdar, M.3
Fazzari, M.4
McCaffrey, J.A.5
Scher, H.I.6
-
30
-
-
84878442860
-
Long-term survival results of a randomized phase III trial of vinflunine plus best supportive care versus best supportive care alone in advanced urothelial carcinoma patients after failure of platinum-based chemotherapy
-
COI: 1:STN:280:DC%2BC3szpsFCitg%3D%3D, PID: 23419284, The updated OS data confirm the positive treatment effect of vinflunine on survival that was previously reported
-
• Bellmunt J, Fougeray R, Rosenberg J, Von der Maase H, Schutz F, Salhi Y, et al. Long-term survival results of a randomized phase III trial of vinflunine plus best supportive care versus best supportive care alone in advanced urothelial carcinoma patients after failure of platinum-based chemotherapy. Ann Oncol. 2013;24(6):1466–72. The updated OS data confirm the positive treatment effect of vinflunine on survival that was previously reported.
-
(2013)
Ann Oncol
, vol.24
, Issue.6
, pp. 1466-1472
-
-
Bellmunt, J.1
Fougeray, R.2
Rosenberg, J.3
Von der Maase, H.4
Schutz, F.5
Salhi, Y.6
-
31
-
-
78249244385
-
Updated survival results of the phase III trial comparing vinflunine (V) to best supportive care (BSC) in advanced transitional cell carcinoma of the urothelium (TCC) after failure of a prior platinum-containing regimen
-
Culine S, Lucas C, Salhi Y, Bellmunt J. Updated survival results of the phase III trial comparing vinflunine (V) to best supportive care (BSC) in advanced transitional cell carcinoma of the urothelium (TCC) after failure of a prior platinum-containing regimen. Eur Urol Suppl. 2010;9(2):38.
-
(2010)
Eur Urol Suppl
, vol.9
, Issue.2
, pp. 38
-
-
Culine, S.1
Lucas, C.2
Salhi, Y.3
Bellmunt, J.4
-
32
-
-
84856358077
-
Influence of age on the pharmacokinetics of iv vinflunine: results of a phase I trial in elderly cancer patients
-
Tourani J, Mourey L, Servent V, Nguyen T, Ravaud A, Girre V, et al. Influence of age on the pharmacokinetics of iv vinflunine: results of a phase I trial in elderly cancer patients. J Geriatr Oncol. 2012;3(1):41–8.
-
(2012)
J Geriatr Oncol
, vol.3
, Issue.1
, pp. 41-48
-
-
Tourani, J.1
Mourey, L.2
Servent, V.3
Nguyen, T.4
Ravaud, A.5
Girre, V.6
-
33
-
-
84978858663
-
Historical data in real life from patients treated by vinflunine for an advanced or metastatic urothelial carcinoma: results of the CURVE study
-
PID: 26975779
-
Medioni J, Guillot A, Spaeth D, Di Palma M, Theodore C. Historical data in real life from patients treated by vinflunine for an advanced or metastatic urothelial carcinoma: results of the CURVE study. BMC Cancer. 2016;16(1):217.
-
(2016)
BMC Cancer
, vol.16
, Issue.1
, pp. 217
-
-
Medioni, J.1
Guillot, A.2
Spaeth, D.3
Di Palma, M.4
Theodore, C.5
-
34
-
-
84900383404
-
Monotherapy with intravenous vinflunine in patients with advanced or metastatic urothelial cancer after failure of a platinum-containing regimen: a retrospective analysis of German routine data
-
PID: 24334998
-
Hegele A, Goebell P, Matz U, Neuhaus T. Monotherapy with intravenous vinflunine in patients with advanced or metastatic urothelial cancer after failure of a platinum-containing regimen: a retrospective analysis of German routine data. Urol Int. 2013;92(2):174–9.
-
(2013)
Urol Int
, vol.92
, Issue.2
, pp. 174-179
-
-
Hegele, A.1
Goebell, P.2
Matz, U.3
Neuhaus, T.4
-
35
-
-
84929939532
-
Safety and effectiveness of vinflunine in patients with metastatic transitional cell carcinoma of the urothelial tract after failure of one platinum-based systemic therapy in clinical practice
-
Castellano D, Puente J, de Velasco G, Chirivella I, López-Criado P, Mohedano N, et al. Safety and effectiveness of vinflunine in patients with metastatic transitional cell carcinoma of the urothelial tract after failure of one platinum-based systemic therapy in clinical practice. BMC Cancer. 2014;14(1):1.
-
(2014)
BMC Cancer
, vol.14
, Issue.1
, pp. 1
-
-
Castellano, D.1
Puente, J.2
de Velasco, G.3
Chirivella, I.4
López-Criado, P.5
Mohedano, N.6
-
36
-
-
84894475296
-
How to manage intravenous vinflunine in cancer patients with renal impairment: results of a pharmacokinetic and tolerability phase I study
-
COI: 1:CAS:528:DC%2BC2cXjt1yqsLc%3D, PID: 24283925
-
Isambert N, Delord JP, Tourani JM, Fumoleau P, Ravaud A, Pinel MC, et al. How to manage intravenous vinflunine in cancer patients with renal impairment: results of a pharmacokinetic and tolerability phase I study. Br J Clin Pharmacol. 2014;77(3):498–508.
-
(2014)
Br J Clin Pharmacol
, vol.77
, Issue.3
, pp. 498-508
-
-
Isambert, N.1
Delord, J.P.2
Tourani, J.M.3
Fumoleau, P.4
Ravaud, A.5
Pinel, M.C.6
-
37
-
-
84879073979
-
Phase I and pharmacokinetic study of IV vinflunine in cancer patients with liver dysfunction
-
COI: 1:CAS:528:DC%2BC3sXnt12ltbc%3D, PID: 22996801
-
Delord J, Ravaud A, Bennouna J, Fumoleau P, Favrel S, Pinel M, et al. Phase I and pharmacokinetic study of IV vinflunine in cancer patients with liver dysfunction. Invest New Drugs. 2013;31(3):724–33.
-
(2013)
Invest New Drugs
, vol.31
, Issue.3
, pp. 724-733
-
-
Delord, J.1
Ravaud, A.2
Bennouna, J.3
Fumoleau, P.4
Favrel, S.5
Pinel, M.6
-
38
-
-
77951626194
-
Prognostic factors in patients with advanced transitional cell carcinoma of the urothelial tract experiencing treatment failure with platinum-containing regimens
-
PID: 20231682
-
Bellmunt J, Choueiri TK, Fougeray R, Schutz FA, Salhi Y, Winquist E, et al. Prognostic factors in patients with advanced transitional cell carcinoma of the urothelial tract experiencing treatment failure with platinum-containing regimens. J Clin Oncol. 2010;28(11):1850–5.
-
(2010)
J Clin Oncol
, vol.28
, Issue.11
, pp. 1850-1855
-
-
Bellmunt, J.1
Choueiri, T.K.2
Fougeray, R.3
Schutz, F.A.4
Salhi, Y.5
Winquist, E.6
-
39
-
-
84874550179
-
Time from prior chemotherapy enhances prognostic risk grouping in the second-line setting of advanced urothelial carcinoma: a retrospective analysis of pooled, prospective phase 2 trials
-
PID: 23206856
-
Sonpavde G, Pond GR, Fougeray R, Choueiri TK, Qu AQ, Vaughn DJ, et al. Time from prior chemotherapy enhances prognostic risk grouping in the second-line setting of advanced urothelial carcinoma: a retrospective analysis of pooled, prospective phase 2 trials. Eur Urol. 2013;63(4):717–23.
-
(2013)
Eur Urol
, vol.63
, Issue.4
, pp. 717-723
-
-
Sonpavde, G.1
Pond, G.R.2
Fougeray, R.3
Choueiri, T.K.4
Qu, A.Q.5
Vaughn, D.J.6
-
40
-
-
84887832973
-
The impact of prior platinum therapy on survival in patients with metastatic urothelial cancer receiving vinflunine
-
COI: 1:CAS:528:DC%2BC3sXhs1Clt7rM, PID: 24129239
-
Harshman L, Fougeray R, Choueiri T, Schutz F, Salhi Y, Rosenberg J, et al. The impact of prior platinum therapy on survival in patients with metastatic urothelial cancer receiving vinflunine. Br J Cancer. 2013;109(10):2548–53.
-
(2013)
Br J Cancer
, vol.109
, Issue.10
, pp. 2548-2553
-
-
Harshman, L.1
Fougeray, R.2
Choueiri, T.3
Schutz, F.4
Salhi, Y.5
Rosenberg, J.6
-
41
-
-
84920575639
-
Impact of the number of prior lines of therapy and prior perioperative chemotherapy in patients receiving salvage therapy for advanced urothelial carcinoma: implications for trial design
-
COI: 1:STN:280:DC%2BC2cfpsFahsQ%3D%3D, PID: 24993933
-
Pond G, Bellmunt J, Rosenberg J, Bajorin D, Regazzi A, Choueiri T, et al. Impact of the number of prior lines of therapy and prior perioperative chemotherapy in patients receiving salvage therapy for advanced urothelial carcinoma: implications for trial design. Clin Genitourin Cancer. 2015;13(1):71–9.
-
(2015)
Clin Genitourin Cancer
, vol.13
, Issue.1
, pp. 71-79
-
-
Pond, G.1
Bellmunt, J.2
Rosenberg, J.3
Bajorin, D.4
Regazzi, A.5
Choueiri, T.6
-
42
-
-
84924598815
-
Complete response as an intermediate end point in patients receiving salvage systemic therapy for urothelial carcinoma
-
PID: 25458370
-
Sonpavde G, Pond GR, Rosenberg JE, Bajorin DF, Regazzi AM, Choueiri TK, et al. Complete response as an intermediate end point in patients receiving salvage systemic therapy for urothelial carcinoma. Clin Genitourin Cancer. 2015;13(2):185–92.
-
(2015)
Clin Genitourin Cancer
, vol.13
, Issue.2
, pp. 185-192
-
-
Sonpavde, G.1
Pond, G.R.2
Rosenberg, J.E.3
Bajorin, D.F.4
Regazzi, A.M.5
Choueiri, T.K.6
-
43
-
-
84862016482
-
Optimisation of the size variation threshold for imaging evaluation of response in patients with platinum-refractory advanced transitional cell carcinoma of the urothelium treated with vinflunine
-
COI: 1:CAS:528:DC%2BC38XosFWiurk%3D, PID: 22176867
-
Krajewski KM, Fougeray R, Bellmunt J, Pons F, Schutz FA, Rosenberg JE, et al. Optimisation of the size variation threshold for imaging evaluation of response in patients with platinum-refractory advanced transitional cell carcinoma of the urothelium treated with vinflunine. Eur J Cancer. 2012;48(10):1495–502.
-
(2012)
Eur J Cancer
, vol.48
, Issue.10
, pp. 1495-1502
-
-
Krajewski, K.M.1
Fougeray, R.2
Bellmunt, J.3
Pons, F.4
Schutz, F.A.5
Rosenberg, J.E.6
-
44
-
-
79956208322
-
Paclitaxel, ifosfamide, and nedaplatin as second‐line treatment for patients with metastatic urothelial carcinoma: a phase II study of the SUOC group
-
COI: 1:CAS:528:DC%2BC3MXnvVGqsbk%3D, PID: 21323791
-
Kitamura H, Taguchi K, Kunishima Y, Yanase M, Takahashi A, Shigyo M, et al. Paclitaxel, ifosfamide, and nedaplatin as second‐line treatment for patients with metastatic urothelial carcinoma: a phase II study of the SUOC group. Cancer Sci. 2011;102(6):1171–5.
-
(2011)
Cancer Sci
, vol.102
, Issue.6
, pp. 1171-1175
-
-
Kitamura, H.1
Taguchi, K.2
Kunishima, Y.3
Yanase, M.4
Takahashi, A.5
Shigyo, M.6
-
45
-
-
38049081245
-
Methotrexate, vinblastine, doxorubicin and cisplatin combination regimen as salvage chemotherapy for patients with advanced or metastatic transitional cell carcinoma after failure of gemcitabine and cisplatin chemotherapy
-
COI: 1:CAS:528:DC%2BD1cXisF2rug%3D%3D, PID: 18087289
-
Han K, Joung J, Kim T, Jeong I, Seo H, Chung J, et al. Methotrexate, vinblastine, doxorubicin and cisplatin combination regimen as salvage chemotherapy for patients with advanced or metastatic transitional cell carcinoma after failure of gemcitabine and cisplatin chemotherapy. Br J Cancer. 2008;98(1):86–90.
-
(2008)
Br J Cancer
, vol.98
, Issue.1
, pp. 86-90
-
-
Han, K.1
Joung, J.2
Kim, T.3
Jeong, I.4
Seo, H.5
Chung, J.6
-
46
-
-
34548250534
-
Weekly paclitaxel and carboplatin against advanced transitional cell cancer after failure of a platinum-based regimen
-
COI: 1:CAS:528:DC%2BD2sXht1WgurfK, PID: 17433855
-
Kouno T, Ando M, Yonemori K, Matsumoto K, Shimizu C, Katsumata N, et al. Weekly paclitaxel and carboplatin against advanced transitional cell cancer after failure of a platinum-based regimen. Eur Urol. 2007;52(4):1115–22.
-
(2007)
Eur Urol
, vol.52
, Issue.4
, pp. 1115-1122
-
-
Kouno, T.1
Ando, M.2
Yonemori, K.3
Matsumoto, K.4
Shimizu, C.5
Katsumata, N.6
-
47
-
-
67651230064
-
A phase II study of docetaxel and oxaliplatin for second-line treatment of urothelial carcinoma
-
COI: 1:CAS:528:DC%2BD1MXhtFyhu7%2FP, PID: 19641314
-
Srinivas S, Harshman LC. A phase II study of docetaxel and oxaliplatin for second-line treatment of urothelial carcinoma. Chemotherapy. 2009;55(5):321–6.
-
(2009)
Chemotherapy
, vol.55
, Issue.5
, pp. 321-326
-
-
Srinivas, S.1
Harshman, L.C.2
-
48
-
-
79955100486
-
Paclitaxel and cisplatin chemotherapy for metastatic urothelial carcinoma after failure of two courses of platinum‐based regimens
-
COI: 1:CAS:528:DC%2BC3MXotlymu70%3D, PID: 21355894
-
Joung JY, Kwon WA, Cho IC, Kim EK, Park S, Yoon H, et al. Paclitaxel and cisplatin chemotherapy for metastatic urothelial carcinoma after failure of two courses of platinum‐based regimens. Int J Urol. 2011;18(5):350–7.
-
(2011)
Int J Urol
, vol.18
, Issue.5
, pp. 350-357
-
-
Joung, J.Y.1
Kwon, W.A.2
Cho, I.C.3
Kim, E.K.4
Park, S.5
Yoon, H.6
-
49
-
-
84860443131
-
Accelerated MVAC chemotherapy in patients with advanced bladder cancer previously treated with a platinum–gemcitabine regimen
-
COI: 1:CAS:528:DC%2BC38XmtlGrurg%3D, PID: 22364733
-
Edeline J, Loriot Y, Culine S, Massard C, Albiges L, Blesius A, et al. Accelerated MVAC chemotherapy in patients with advanced bladder cancer previously treated with a platinum–gemcitabine regimen. Eur J Cancer. 2012;48(8):1141–6.
-
(2012)
Eur J Cancer
, vol.48
, Issue.8
, pp. 1141-1146
-
-
Edeline, J.1
Loriot, Y.2
Culine, S.3
Massard, C.4
Albiges, L.5
Blesius, A.6
-
50
-
-
70449345853
-
Do patients with advanced urothelial carcinoma benefit from weekly paclitaxel chemotherapy? A GETUG phase II study
-
COI: 1:CAS:528:DC%2BC3MXptVKk, PID: 19692319
-
Joly F, Houédé N, Noal S, Chevreau C, Priou F, Chinet-Charrot P, et al. Do patients with advanced urothelial carcinoma benefit from weekly paclitaxel chemotherapy? A GETUG phase II study. Clin Genitourin Cancer. 2009;7(2):E28–33.
-
(2009)
Clin Genitourin Cancer
, vol.7
, Issue.2
, pp. E28-E33
-
-
Joly, F.1
Houédé, N.2
Noal, S.3
Chevreau, C.4
Priou, F.5
Chinet-Charrot, P.6
-
51
-
-
0035892761
-
Chemotherapy with an every‐2‐week regimen of gemcitabine and paclitaxel in patients with transitional cell carcinoma who have received prior cisplatin‐based therapy
-
COI: 1:CAS:528:DC%2BD38XjvVejsw%3D%3D, PID: 11753976
-
Sternberg CN, Calabro F, Pizzocaro G, Marini L, Schnetzer S, Sella A. Chemotherapy with an every‐2‐week regimen of gemcitabine and paclitaxel in patients with transitional cell carcinoma who have received prior cisplatin‐based therapy. Cancer. 2001;92(12):2993–299.
-
(2001)
Cancer
, vol.92
, Issue.12
, pp. 2299-2993
-
-
Sternberg, C.N.1
Calabro, F.2
Pizzocaro, G.3
Marini, L.4
Schnetzer, S.5
Sella, A.6
-
52
-
-
57849147736
-
Gemcitabine and paclitaxel chemotherapy for advanced urothelial carcinoma in patients who have received prior cisplatin-based chemotherapy
-
COI: 1:CAS:528:DC%2BD1cXhsFSrurjL, PID: 19093178
-
Kanai K, Kikuchi E, Ohigashi T, Miyajima A, Nakagawa K, Nakashima J, et al. Gemcitabine and paclitaxel chemotherapy for advanced urothelial carcinoma in patients who have received prior cisplatin-based chemotherapy. Int J Clin Oncol. 2008;13(6):510–4.
-
(2008)
Int J Clin Oncol
, vol.13
, Issue.6
, pp. 510-514
-
-
Kanai, K.1
Kikuchi, E.2
Ohigashi, T.3
Miyajima, A.4
Nakagawa, K.5
Nakashima, J.6
-
53
-
-
33644834714
-
Randomised phase II trial of gemcitabine and paclitaxel second‐line chemotherapy in patients with transitional cell carcinoma (AUO Trial AB 20/99)
-
COI: 1:CAS:528:DC%2BD28XitFSltb8%3D, PID: 16409425
-
Fechner G, Siener R, Reimann M, Kobalz L, Albers P. Randomised phase II trial of gemcitabine and paclitaxel second‐line chemotherapy in patients with transitional cell carcinoma (AUO Trial AB 20/99). Int J Clin Pract. 2006;60(1):27–31.
-
(2006)
Int J Clin Pract
, vol.60
, Issue.1
, pp. 27-31
-
-
Fechner, G.1
Siener, R.2
Reimann, M.3
Kobalz, L.4
Albers, P.5
-
54
-
-
79251542085
-
Randomized phase III trial of 2nd line gemcitabine and paclitaxel chemotherapy in patients with advanced bladder cancer: short-term versus prolonged treatment [German Association of Urological Oncology (AUO) trial AB 20/99]
-
COI: 1:STN:280:DC%2BC3M3htlGmtg%3D%3D, PID: 20682548
-
Albers P, Park S-I, Niegisch G, Fechner G, Steiner U, Lehmann J, et al. Randomized phase III trial of 2nd line gemcitabine and paclitaxel chemotherapy in patients with advanced bladder cancer: short-term versus prolonged treatment [German Association of Urological Oncology (AUO) trial AB 20/99]. Ann Oncol. 2011;22(2):288–94.
-
(2011)
Ann Oncol
, vol.22
, Issue.2
, pp. 288-294
-
-
Albers, P.1
Park, S.-I.2
Niegisch, G.3
Fechner, G.4
Steiner, U.5
Lehmann, J.6
-
55
-
-
84856851592
-
Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer
-
COI: 1:CAS:528:DC%2BC38XkvVCit7w%3D, PID: 22184381
-
Choueiri TK, Ross RW, Jacobus S, Vaishampayan U, Evan YY, Quinn DI, et al. Double-blind, randomized trial of docetaxel plus vandetanib versus docetaxel plus placebo in platinum-pretreated metastatic urothelial cancer. J Clin Oncol. 2012;30(5):507–12.
-
(2012)
J Clin Oncol
, vol.30
, Issue.5
, pp. 507-512
-
-
Choueiri, T.K.1
Ross, R.W.2
Jacobus, S.3
Vaishampayan, U.4
Evan, Y.Y.5
Quinn, D.I.6
-
56
-
-
84879787404
-
Nanoparticle albumin-bound paclitaxel for second-line treatment of metastatic urothelial carcinoma: a single group, multicentre, phase 2 study
-
COI: 1:CAS:528:DC%2BC3sXosVOhu7o%3D, PID: 23706985
-
Ko Y-J, Canil CM, Mukherjee SD, Winquist E, Elser C, Eisen A, et al. Nanoparticle albumin-bound paclitaxel for second-line treatment of metastatic urothelial carcinoma: a single group, multicentre, phase 2 study. Lancet Oncol. 2013;14(8):769–76.
-
(2013)
Lancet Oncol
, vol.14
, Issue.8
, pp. 769-776
-
-
Ko, Y.-J.1
Canil, C.M.2
Mukherjee, S.D.3
Winquist, E.4
Elser, C.5
Eisen, A.6
-
57
-
-
0031017367
-
Eastern Cooperative Oncology Group phase II trial of ifosfamide in the treatment of previously treated advanced urothelial carcinoma
-
COI: 1:CAS:528:DyaK2sXhsVamsrc%3D, PID: 9053481
-
Witte RS, Elson P, Bono B, Knop R, Richardson RR, Dreicer R, et al. Eastern Cooperative Oncology Group phase II trial of ifosfamide in the treatment of previously treated advanced urothelial carcinoma. J Clin Oncol. 1997;15(2):589–93.
-
(1997)
J Clin Oncol
, vol.15
, Issue.2
, pp. 589-593
-
-
Witte, R.S.1
Elson, P.2
Bono, B.3
Knop, R.4
Richardson, R.R.5
Dreicer, R.6
-
58
-
-
0032127772
-
A phase II study of gemcitabine in patients with transitional cell carcinoma of the urinary tract previously treated with platinum
-
COI: 1:CAS:528:DyaK1cXltlCgsr4%3D, PID: 9849481
-
Lorusso V, Pollera C, Antimi M, Luporini G, Gridelli C, Frassineti G, et al. A phase II study of gemcitabine in patients with transitional cell carcinoma of the urinary tract previously treated with platinum. Eur J Cancer. 1998;34(8):1208–12.
-
(1998)
Eur J Cancer
, vol.34
, Issue.8
, pp. 1208-1212
-
-
Lorusso, V.1
Pollera, C.2
Antimi, M.3
Luporini, G.4
Gridelli, C.5
Frassineti, G.6
-
59
-
-
0032894858
-
Single agent 2′, 2′-difluorodeoxycytidine in the treatment of metastatic urothelial carcinoma: a phase II study
-
Gebbia V, Testa A, Borsellino N, Mauceri G, Varvara F, Tirrito M, et al. Single agent 2′, 2′-difluorodeoxycytidine in the treatment of metastatic urothelial carcinoma: a phase II study. Clin Ter. 1998;150(1):11–5.
-
(1998)
Clin Ter
, vol.150
, Issue.1
, pp. 11-15
-
-
Gebbia, V.1
Testa, A.2
Borsellino, N.3
Mauceri, G.4
Varvara, F.5
Tirrito, M.6
-
60
-
-
0036118968
-
Gemcitabine monotherapy as second-line treatment in cisplatin-refractory transitional cell carcinoma—prognostic factors for response and improvement of quality of life
-
COI: 1:STN:280:DC%2BD387mt1ajsg%3D%3D, PID: 11893883
-
Albers P, Siener R, Härtlein M, Fallahi M, Haeutle D, Perabo F, et al. Gemcitabine monotherapy as second-line treatment in cisplatin-refractory transitional cell carcinoma—prognostic factors for response and improvement of quality of life. Onkologie. 2002;25(1):47–52.
-
(2002)
Onkologie
, vol.25
, Issue.1
, pp. 47-52
-
-
Albers, P.1
Siener, R.2
Härtlein, M.3
Fallahi, M.4
Haeutle, D.5
Perabo, F.6
-
61
-
-
34447634926
-
Efficacy and safety of gemcitabine monotherapy in patients with transitional cell carcinoma after Cisplatin-containing therapy: a Japanese experience
-
PID: 17452426
-
Akaza H, Naito S, Usami M, Miki T, Miyanaga N, Taniai H. Efficacy and safety of gemcitabine monotherapy in patients with transitional cell carcinoma after Cisplatin-containing therapy: a Japanese experience. Jpn J Clin Oncol. 2007;37(3):201–6.
-
(2007)
Jpn J Clin Oncol
, vol.37
, Issue.3
, pp. 201-206
-
-
Akaza, H.1
Naito, S.2
Usami, M.3
Miki, T.4
Miyanaga, N.5
Taniai, H.6
-
62
-
-
84994288117
-
Efficacy of single-agent pemetrexed in platinum refractory metastatic urothelial cancer (mUC)
-
Benjamin DJ, Bambury RM, Chaim J, Zabor EC, Ostrovnaya I, Garcia-Grossman IR, et al. Efficacy of single-agent pemetrexed in platinum refractory metastatic urothelial cancer (mUC). ASCO Annu Meet Proc. 2014;32(4 suppl):322.
-
(2014)
ASCO Annu Meet Proc
, vol.32
, pp. 322
-
-
Benjamin, D.J.1
Bambury, R.M.2
Chaim, J.3
Zabor, E.C.4
Ostrovnaya, I.5
Garcia-Grossman, I.R.6
-
63
-
-
84893520397
-
Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy
-
COI: 1:CAS:528:DC%2BC2cXitleqtbc%3D, PID: 24525232, Muscle-invasive bladder cancers (MIBCs) are biologically heterogeneous and have widely variable clinical outcomes and responses to conventional chemotherapy. In this study, three molecular subtypes of MIBC are identified and these have important implications for prognostication, the future clinical development of targeted agents, and disease management with conventional chemotherapy
-
•• Choi W, Porten S, Kim S, Willis D, Plimack ER, Hoffman-Censits J, et al. Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy. Cancer Cell. 2014;25(2):152–65. Muscle-invasive bladder cancers (MIBCs) are biologically heterogeneous and have widely variable clinical outcomes and responses to conventional chemotherapy. In this study, three molecular subtypes of MIBC are identified and these have important implications for prognostication, the future clinical development of targeted agents, and disease management with conventional chemotherapy.
-
(2014)
Cancer Cell
, vol.25
, Issue.2
, pp. 152-165
-
-
Choi, W.1
Porten, S.2
Kim, S.3
Willis, D.4
Plimack, E.R.5
Hoffman-Censits, J.6
-
64
-
-
84896844735
-
Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology
-
COI: 1:CAS:528:DC%2BC2cXjtVGrsb8%3D, PID: 24520177
-
Damrauer JS, Hoadley KA, Chism DD, Fan C, Tiganelli CJ, Wobker SE, et al. Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology. Proc Natl Acad Sci. 2014;111(8):3110–5.
-
(2014)
Proc Natl Acad Sci
, vol.111
, Issue.8
, pp. 3110-3115
-
-
Damrauer, J.S.1
Hoadley, K.A.2
Chism, D.D.3
Fan, C.4
Tiganelli, C.J.5
Wobker, S.E.6
-
65
-
-
84897022815
-
Comprehensive molecular characterization of urothelial bladder carcinoma
-
Network CGAR. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature. 2014;507(7492):315–22.
-
(2014)
Nature
, vol.507
, Issue.7492
, pp. 315-322
-
-
Network, C.G.A.R.1
-
66
-
-
84924359606
-
The role of genomics in the management of advanced bladder cancer
-
Guancial EA, Rosenberg JE. The role of genomics in the management of advanced bladder cancer. Curr Treat Options Oncol. 2015;16(1):1–15.
-
(2015)
Curr Treat Options Oncol
, vol.16
, Issue.1
, pp. 1-15
-
-
Guancial, E.A.1
Rosenberg, J.E.2
-
67
-
-
84921651021
-
Emerging therapeutic targets in bladder cancer
-
COI: 1:CAS:528:DC%2BC2cXitVShsrzE, PID: 25498841
-
Carneiro BA, Meeks JJ, Kuzel TM, Scaranti M, Abdulkadir SA, Giles FJ. Emerging therapeutic targets in bladder cancer. Cancer Treat Rev. 2015;41(2):170–8.
-
(2015)
Cancer Treat Rev
, vol.41
, Issue.2
, pp. 170-178
-
-
Carneiro, B.A.1
Meeks, J.J.2
Kuzel, T.M.3
Scaranti, M.4
Abdulkadir, S.A.5
Giles, F.J.6
-
68
-
-
84904397559
-
NVP-BEZ235, a dual PI3K/mTOR inhibitor synergistically potentiates the antitumor effects of cisplatin in bladder cancer cells
-
COI: 1:CAS:528:DC%2BC2cXhsFWhtbrJ
-
Moon DG, Lee SE, Oh MM, Lee SC, Jeong SJ, Hong SK, et al. NVP-BEZ235, a dual PI3K/mTOR inhibitor synergistically potentiates the antitumor effects of cisplatin in bladder cancer cells. Int J Oncol. 2014;45(3):1027–35.
-
(2014)
Int J Oncol
, vol.45
, Issue.3
, pp. 1027-1035
-
-
Moon, D.G.1
Lee, S.E.2
Oh, M.M.3
Lee, S.C.4
Jeong, S.J.5
Hong, S.K.6
-
69
-
-
84880781405
-
Phase II study of everolimus in metastatic urothelial cancer
-
COI: 1:CAS:528:DC%2BC3sXhtFOltrfM, PID: 23551593
-
Milowsky MI, Iyer G, Regazzi AM, Al‐Ahmadie H, Gerst SR, Ostrovnaya I, et al. Phase II study of everolimus in metastatic urothelial cancer. BJU Int. 2013;112(4):462–70.
-
(2013)
BJU Int
, vol.112
, Issue.4
, pp. 462-470
-
-
Milowsky, M.I.1
Iyer, G.2
Regazzi, A.M.3
Al‐Ahmadie, H.4
Gerst, S.R.5
Ostrovnaya, I.6
-
70
-
-
70349667473
-
Spectrum of phosphatidylinositol 3-kinase pathway gene alterations in bladder cancer
-
COI: 1:CAS:528:DC%2BD1MXhtF2ltbbF, PID: 19789314
-
Platt FM, Hurst CD, Taylor CF, Gregory WM, Harnden P, Knowles MA. Spectrum of phosphatidylinositol 3-kinase pathway gene alterations in bladder cancer. Clin Cancer Res. 2009;15(19):6008–17.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.19
, pp. 6008-6017
-
-
Platt, F.M.1
Hurst, C.D.2
Taylor, C.F.3
Gregory, W.M.4
Harnden, P.5
Knowles, M.A.6
-
71
-
-
84860532107
-
Dual mTORC1/2 and HER2 blockade results in antitumor activity in preclinical models of breast cancer resistant to anti-HER2 therapy
-
PID: 22407832
-
García-García C, Ibrahim YH, Serra V, Calvo MT, Guzmán M, Grueso J, et al. Dual mTORC1/2 and HER2 blockade results in antitumor activity in preclinical models of breast cancer resistant to anti-HER2 therapy. Clin Cancer Res. 2012;18(9):2603–12.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.9
, pp. 2603-2612
-
-
García-García, C.1
Ibrahim, Y.H.2
Serra, V.3
Calvo, M.T.4
Guzmán, M.5
Grueso, J.6
-
72
-
-
84867083523
-
Phase II trial of cetuximab with or without paclitaxel in patients with advanced urothelial tract carcinoma
-
COI: 1:CAS:528:DC%2BC38XhslSks77O, PID: 22927525
-
Wong Y-N, Litwin S, Vaughn D, Cohen S, Plimack ER, Lee J, et al. Phase II trial of cetuximab with or without paclitaxel in patients with advanced urothelial tract carcinoma. J Clin Oncol. 2012;30(28):3545–51.
-
(2012)
J Clin Oncol
, vol.30
, Issue.28
, pp. 3545-3551
-
-
Wong, Y.-N.1
Litwin, S.2
Vaughn, D.3
Cohen, S.4
Plimack, E.R.5
Lee, J.6
-
73
-
-
75149171017
-
Results of the Southwest Oncology Group phase II evaluation (study S0031) of ZD1839 for advanced transitional cell carcinoma of the urothelium
-
COI: 1:CAS:528:DC%2BC3cXitlKnsbo%3D, PID: 19888985
-
Petrylak DP, Tangen CM, Van Veldhuizen PJ, Goodwin JW, Twardowski PW, Atkins JN, et al. Results of the Southwest Oncology Group phase II evaluation (study S0031) of ZD1839 for advanced transitional cell carcinoma of the urothelium. BJU Int. 2010;105(3):317–21.
-
(2010)
BJU Int
, vol.105
, Issue.3
, pp. 317-321
-
-
Petrylak, D.P.1
Tangen, C.M.2
Van Veldhuizen, P.J.3
Goodwin, J.W.4
Twardowski, P.W.5
Atkins, J.N.6
-
74
-
-
67649579849
-
A single‐arm, multicenter, open‐label phase 2 study of lapatinib as the second‐line treatment of patients with locally advanced or metastatic transitional cell carcinoma
-
PID: 19399906
-
Wülfing C, Machiels JPH, Richel DJ, Grimm MO, Treiber U, De Groot MR, et al. A single‐arm, multicenter, open‐label phase 2 study of lapatinib as the second‐line treatment of patients with locally advanced or metastatic transitional cell carcinoma. Cancer. 2009;115(13):2881–90.
-
(2009)
Cancer
, vol.115
, Issue.13
, pp. 2881-2890
-
-
Wülfing, C.1
Machiels, J.P.H.2
Richel, D.J.3
Grimm, M.O.4
Treiber, U.5
De Groot, M.R.6
-
75
-
-
84866987918
-
Combining paclitaxel and lapatinib as second-line treatment for patients with metastatic transitional cell carcinoma: a case series
-
COI: 1:CAS:528:DC%2BC38XhsFKmt7bM, PID: 22993342
-
Culine S, Sellam Z, Bouaita L, Assaf E, Delbaldo C, Verlinde-Carvalho M, et al. Combining paclitaxel and lapatinib as second-line treatment for patients with metastatic transitional cell carcinoma: a case series. Anticancer Res. 2012;32(9):3949–52.
-
(2012)
Anticancer Res
, vol.32
, Issue.9
, pp. 3949-3952
-
-
Culine, S.1
Sellam, Z.2
Bouaita, L.3
Assaf, E.4
Delbaldo, C.5
Verlinde-Carvalho, M.6
-
76
-
-
34250218955
-
Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: results of a multicenter phase II National Cancer Institute trial
-
COI: 1:CAS:528:DC%2BD2sXnsVShtbs%3D, PID: 17538166
-
Hussain MH, MacVicar GR, Petrylak DP, Dunn RL, Vaishampayan U, Lara PN, et al. Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: results of a multicenter phase II National Cancer Institute trial. J Clin Oncol. 2007;25(16):2218–24.
-
(2007)
J Clin Oncol
, vol.25
, Issue.16
, pp. 2218-2224
-
-
Hussain, M.H.1
MacVicar, G.R.2
Petrylak, D.P.3
Dunn, R.L.4
Vaishampayan, U.5
Lara, P.N.6
-
77
-
-
70149124507
-
Phase 2 trial of sorafenib in patients with advanced urothelial cancer
-
COI: 1:CAS:528:DC%2BD1MXhtF2ktbnL, PID: 19536901
-
Dreicer R, Li H, Stein M, DiPaola R, Eleff M, Roth BJ, et al. Phase 2 trial of sorafenib in patients with advanced urothelial cancer. Cancer. 2009;115(18):4090–5.
-
(2009)
Cancer
, vol.115
, Issue.18
, pp. 4090-4095
-
-
Dreicer, R.1
Li, H.2
Stein, M.3
DiPaola, R.4
Eleff, M.5
Roth, B.J.6
-
78
-
-
77950474660
-
Phase II study of sunitinib in patients with metastatic urothelial cancer
-
COI: 1:CAS:528:DC%2BC3cXksFSqurw%3D, PID: 20142593
-
Gallagher DJ, Milowsky MI, Gerst SR, Ishill N, Riches J, Regazzi A, et al. Phase II study of sunitinib in patients with metastatic urothelial cancer. J Clin Oncol. 2010;28(8):1373–9.
-
(2010)
J Clin Oncol
, vol.28
, Issue.8
, pp. 1373-1379
-
-
Gallagher, D.J.1
Milowsky, M.I.2
Gerst, S.R.3
Ishill, N.4
Riches, J.5
Regazzi, A.6
-
79
-
-
84864337145
-
Pazopanib in advanced and platinum-resistant urothelial cancer: an open-label, single group, phase 2 trial
-
COI: 1:CAS:528:DC%2BC38XhtFajsLnP
-
Necchi A, Mariani L, Zaffaroni N, Schwartz LH, Giannatempo P, Crippa F, et al. Pazopanib in advanced and platinum-resistant urothelial cancer: an open-label, single group, phase 2 trial. Lancer Oncol. 2012;13(8):810–6.
-
(2012)
Lancer Oncol
, vol.13
, Issue.8
, pp. 810-816
-
-
Necchi, A.1
Mariani, L.2
Zaffaroni, N.3
Schwartz, L.H.4
Giannatempo, P.5
Crippa, F.6
-
80
-
-
77957756488
-
Phase II study of aflibercept (VEGF-Trap) in patients with recurrent or metastatic urothelial cancer, a California Cancer Consortium Trial
-
PID: 20646741
-
Twardowski P, Stadler WM, Frankel P, Lara PN, Ruel C, Chatta G, et al. Phase II study of aflibercept (VEGF-Trap) in patients with recurrent or metastatic urothelial cancer, a California Cancer Consortium Trial. Urology. 2010;76(4):923–6.
-
(2010)
Urology
, vol.76
, Issue.4
, pp. 923-926
-
-
Twardowski, P.1
Stadler, W.M.2
Frankel, P.3
Lara, P.N.4
Ruel, C.5
Chatta, G.6
-
81
-
-
84904254200
-
FGFR3 translocations in bladder cancer: differential sensitivity to HSP90 inhibition based on drug metabolism
-
COI: 1:CAS:528:DC%2BC2cXhtFCrtbjP, PID: 24784839
-
Acquaviva J, He S, Zhang C, Jimenez J-P, Nagai M, Sang J, et al. FGFR3 translocations in bladder cancer: differential sensitivity to HSP90 inhibition based on drug metabolism. Mol Cancer Res. 2014;12(7):1042–54.
-
(2014)
Mol Cancer Res
, vol.12
, Issue.7
, pp. 1042-1054
-
-
Acquaviva, J.1
He, S.2
Zhang, C.3
Jimenez, J.-P.4
Nagai, M.5
Sang, J.6
-
82
-
-
84923078390
-
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
-
COI: 1:CAS:528:DC%2BC2cXitFamsrjE, PID: 25428503
-
Powles T, Eder JP, Fine GD, Braiteh FS, Loriot Y, Cruz C, et al. MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature. 2014;515(7528):558–62.
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 558-562
-
-
Powles, T.1
Eder, J.P.2
Fine, G.D.3
Braiteh, F.S.4
Loriot, Y.5
Cruz, C.6
-
83
-
-
84959577118
-
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase II trial
-
Atezolizumab showed durable activity and good tolerability in patients with advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy. This study show the association of TCGA subtypes with response to immune checkpoint inhibition
-
•• Rosemberg JE, Hoffman-Censits C, Powles T, van der Heijden MS, Balar AV, Necchi A, et al. Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase II trial. Lancet. 2016;387:1909–20. Atezolizumab showed durable activity and good tolerability in patients with advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy. This study show the association of TCGA subtypes with response to immune checkpoint inhibition.
-
(2016)
Lancet
, vol.387
, pp. 1909-1920
-
-
Rosemberg, J.E.1
Hoffman-Censits, C.2
Powles, T.3
van der Heijden, M.S.4
Balar, A.V.5
Necchi, A.6
-
84
-
-
84947267135
-
Heath K et al., editors. Pembrolizumab (MK-3475) for advanced urothelial cancer: updated results and biomarker analysis from KEYNOTE-012
-
Plimack ER, Bellmunt J, Gupta S, Berger R, Montgomery RB, Heath K et al., editors. Pembrolizumab (MK-3475) for advanced urothelial cancer: updated results and biomarker analysis from KEYNOTE-012. ASCO Annual Meeting Proceedings; 2015.
-
(2015)
ASCO Annual Meeting Proceedings
-
-
Plimack, E.R.1
Bellmunt, J.2
Gupta, S.3
Berger, R.4
Montgomery, R.B.5
|