메뉴 건너뛰기




Volumn 126, Issue 9, 2016, Pages 688-696

Optimizing the safety of treatment for venous thromboembolism in the era of direct oral anticoagulants

Author keywords

Bleeding risk; Direct oral anticoagulants; Periprocedural management; Venous thromboembolism

Indexed keywords

ANDEXANET ALFA; APIXABAN; CIRAPARANTAG; DABIGATRAN; EDOXABAN; IDARUCIZUMAB; PROTHROMBIN COMPLEX; RIVAROXABAN; WARFARIN; ANTICOAGULANT AGENT; COAGULATING AGENT; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIDONE DERIVATIVE; THIAZOLE DERIVATIVE;

EID: 84994226102     PISSN: 00323772     EISSN: 18979483     Source Type: Journal    
DOI: 10.20452/pamw.3547     Document Type: Review
Times cited : (27)

References (48)
  • 1
    • 70350551984 scopus 로고    scopus 로고
    • Incidence rates, clinical profile, and outcomes of patients with venous thromboembolism. The Worcester VTE study
    • Spencer FA, Emery C, Joffe SW, et al. Incidence rates, clinical profile, and outcomes of patients with venous thromboembolism. The Worcester VTE study. J Thromb Thrombolysis. 2009; 28: 401-409.
    • (2009) J Thromb Thrombolysis. , vol.28 , pp. 401-409
    • Spencer, F.A.1    Emery, C.2    Joffe, S.W.3
  • 2
    • 0038380256 scopus 로고    scopus 로고
    • The epidemiology of venous thromboembolism
    • White RH. The epidemiology of venous thromboembolism. Circulation. 2003; 107: SI4-SI8.
    • (2003) Circulation. , vol.107 , pp. SI4-SI8
    • White, R.H.1
  • 3
    • 0032559775 scopus 로고    scopus 로고
    • Trends in the incidence of deep vein thrombosis and pulmonary embolism: A 25-year population-based study
    • Silverstein MD, Heit JA, Mohr DN, et al. Trends in the incidence of deep vein thrombosis and pulmonary embolism: A 25-year population-based study. Arch Intern Med. 1998; 158: 585-593.
    • (1998) Arch Intern Med. , vol.158 , pp. 585-593
    • Silverstein, M.D.1    Heit, J.A.2    Mohr, D.N.3
  • 4
    • 0033535363 scopus 로고    scopus 로고
    • Predictors of survival after deep vein thrombosis and pulmonary embolism: A population-based, cohort study
    • Heit JA, Silverstein MD, Mohr DN, et al. Predictors of survival after deep vein thrombosis and pulmonary embolism: A population-based, cohort study. Arch Intern Med. 1999; 159: 445-453.
    • (1999) Arch Intern Med. , vol.159 , pp. 445-453
    • Heit, J.A.1    Silverstein, M.D.2    Mohr, D.N.3
  • 5
    • 0037704209 scopus 로고    scopus 로고
    • Natural history of venous thromboembolism
    • Kearon C. Natural history of venous thromboembolism. Circulation. 2003; 107: SI22-SI30.
    • (2003) Circulation. , vol.107 , pp. SI22-SI30
    • Kearon, C.1
  • 6
    • 34249829228 scopus 로고    scopus 로고
    • The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. A prospective cohort study in 1 626 patients
    • Prandoni P, Noventa F, Ghirarduzzi A, et al. The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. A prospective cohort study in 1 626 patients. Haematologica. 2007; 92: 199-205.
    • (2007) Haematologica. , vol.92 , pp. 199-205
    • Prandoni, P.1    Noventa, F.2    Ghirarduzzi, A.3
  • 7
    • 0030317948 scopus 로고    scopus 로고
    • The long-term clinical course of acute deep venous thrombosis
    • Prandoni P, Lensing AW, Cogo A, et al. The long-term clinical course of acute deep venous thrombosis. Ann Intern Med. 1996; 125: 1-7.
    • (1996) Ann Intern Med. , vol.125 , pp. 1-7
    • Prandoni, P.1    Lensing, A.W.2    Cogo, A.3
  • 8
    • 2442643903 scopus 로고    scopus 로고
    • Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism
    • Pengo V, Lensing AW, Prins MH, et al. Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism. N Engl J Med. 2004; 350: 2257-2264.
    • (2004) N Engl J Med. , vol.350 , pp. 2257-2264
    • Pengo, V.1    Lensing, A.W.2    Prins, M.H.3
  • 9
    • 71849117615 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in the treatment of acute venous thromboembolism
    • Schulman S, Kearon C, Kakkar AK, et al. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med. 2009; 361: 2342-2352.
    • (2009) N Engl J Med. , vol.361 , pp. 2342-2352
    • Schulman, S.1    Kearon, C.2    Kakkar, A.K.3
  • 10
    • 84894295323 scopus 로고    scopus 로고
    • Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis
    • Schulman S, Kakkar AK, Goldhaber SZ, et al. Treatment of acute venous thromboembolism with dabigatran or warfarin and pooled analysis. Circulation. 2013; 129: 764-772.
    • (2013) Circulation. , vol.129 , pp. 764-772
    • Schulman, S.1    Kakkar, A.K.2    Goldhaber, S.Z.3
  • 11
    • 78650619315 scopus 로고    scopus 로고
    • Oral rivaroxaban for symptomatic venous thromboembolism
    • Bauersachs R, Berkowitz SD, Brenner B, et al. Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med. 2010; 363: 2499-2510.
    • (2010) N Engl J Med. , vol.363 , pp. 2499-2510
    • Bauersachs, R.1    Berkowitz, S.D.2    Brenner, B.3
  • 12
    • 84859385808 scopus 로고    scopus 로고
    • Oral rivaroxaban for the treatment of symptomatic pulmonary embolism
    • Buller HR, Prins MH, Lensing AW, et al. Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med. 2012; 366: 1287-1297.
    • (2012) N Engl J Med. , vol.366 , pp. 1287-1297
    • Buller, H.R.1    Prins, M.H.2    Lensing, A.W.3
  • 13
    • 84880327613 scopus 로고    scopus 로고
    • Oral apixaban for the treatment of acute venous thromboembolism
    • Agnelli G, Buller HR, Cohen A, et al. Oral apixaban for the treatment of acute venous thromboembolism. N Engl J Med. 2013; 369: 799-808.
    • (2013) N Engl J Med. , vol.369 , pp. 799-808
    • Agnelli, G.1    Buller, H.R.2    Cohen, A.3
  • 14
    • 84885618705 scopus 로고    scopus 로고
    • Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism
    • Buller HR, Decousus H, Grosso M, et al. Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med. 2013; 369: 1406-1415.
    • (2013) N Engl J Med. , vol.369 , pp. 1406-1415
    • Buller, H.R.1    Decousus, H.2    Grosso, M.3
  • 15
    • 84907202540 scopus 로고    scopus 로고
    • Direct oral anticoagulants compared with Vitamin K antagonists for acute venous thromboembolism: Evidence from phase 3 trials
    • van Es N, Coppens M, Schulman S, et al. Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials. Blood. 2014; 124: 1968-1975.
    • (2014) Blood. , vol.124 , pp. 1968-1975
    • Van Es, N.1    Coppens, M.2    Schulman, S.3
  • 16
    • 84873596181 scopus 로고    scopus 로고
    • Apixaban for extended treatment of venous thromboembolism
    • Agnelli G, Buller HR, Cohen A, et al. Apixaban for extended treatment of venous thromboembolism. N Engl J Med. 2013; 368: 699-708.
    • (2013) N Engl J Med. , vol.368 , pp. 699-708
    • Agnelli, G.1    Buller, H.R.2    Cohen, A.3
  • 17
    • 84874003257 scopus 로고    scopus 로고
    • Extended use of dabigatran, warfarin, or placebo in venous thromboembolism
    • Schulman S, Kearon C, Kakkar AK, et al. Extended Use of Dabigatran, Warfarin, or Placebo in Venous Thromboembolism. N Engl J Med. 2013; 368: 709-718.
    • (2013) N Engl J Med. , vol.368 , pp. 709-718
    • Schulman, S.1    Kearon, C.2    Kakkar, A.K.3
  • 18
    • 84941875041 scopus 로고    scopus 로고
    • Safety and efficacy of direct oral anticoagulants compared to warfarin for extended treatment of venous thromboembolism-A systematic review and meta-analysis
    • Sindet-Pedersen C, Pallisgaard JL, Olesen JB, et al. Safety and efficacy of direct oral anticoagulants compared to warfarin for extended treatment of venous thromboembolism-A systematic review and meta-analysis. Thromb Res. 2015; 136: 732-738.
    • (2015) Thromb Res. , vol.136 , pp. 732-738
    • Sindet-Pedersen, C.1    Pallisgaard, J.L.2    Olesen, J.B.3
  • 19
    • 84958050875 scopus 로고    scopus 로고
    • Extended anticoagulant and aspirin treatment for the secondary prevention of thromboembolic disease: A systematic review and meta-analysis
    • Marik PE, Cavallazzi R. Extended anticoagulant and aspirin treatment for the secondary prevention of thromboembolic disease: A systematic review and meta-analysis. PLoS One. 2015; 10: e0143252.
    • (2015) PLoS One. , vol.10 , pp. e0143252
    • Marik, P.E.1    Cavallazzi, R.2
  • 20
    • 0042031415 scopus 로고    scopus 로고
    • Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for longterm prevention of recurrent venous thromboembolism
    • Kearon C, Ginsberg JS, Kovacs MJ, et al. Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for longterm prevention of recurrent venous thromboembolism. N Engl J Med. 2003; 349: 631-639.
    • (2003) N Engl J Med. , vol.349 , pp. 631-639
    • Kearon, C.1    Ginsberg, J.S.2    Kovacs, M.J.3
  • 21
    • 84940654819 scopus 로고    scopus 로고
    • Two doses of rivaroxaban versus aspirin for prevention of recurrent venous thromboembolism. Rationale for and design of the Einstein CHOICE study
    • Weitz JI, Bauersachs R, Beyer-Westendorf J, et al. Two doses of rivaroxaban versus aspirin for prevention of recurrent venous thromboembolism. Rationale for and design of the EINSTEIN CHOICE study. Thromb Haemost. 2015;114: 645-650.
    • (2015) Thromb Haemost. , vol.114 , pp. 645-650
    • Weitz, J.I.1    Bauersachs, R.2    Beyer-Westendorf, J.3
  • 22
    • 84923167380 scopus 로고    scopus 로고
    • Venous thromboembolism prophylaxis and treatment in patients with cancer: American society of clinical oncology clinical practice guideline update 2014
    • Lyman GH, Bohlke K, Khorana AA, et al. Venous thromboembolism prophylaxis and treatment in patients with cancer: american society of clinical oncology clinical practice guideline update 2014. J Clin Oncol. 2015; 33: 654-656.
    • (2015) J Clin Oncol. , vol.33 , pp. 654-656
    • Lyman, G.H.1    Bohlke, K.2    Khorana, A.A.3
  • 23
    • 84958038787 scopus 로고    scopus 로고
    • Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report
    • Kearon C, Akl EA, Ornelas J, et al. Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report. Chest. 2016; 149: 315-352.
    • (2016) Chest. , vol.149 , pp. 315-352
    • Kearon, C.1    Akl, E.A.2    Ornelas, J.3
  • 24
    • 84974728198 scopus 로고    scopus 로고
    • Use of the direct oral anticoagulants in obese patients: Guidance from the SSC of the ISTH
    • Martin K, Beyer-Westendorf J, Davidson BL, et al. Use of the direct oral anticoagulants in obese patients: guidance from the SSC of the ISTH. J Thromb Haemost. 2016; 14: 1308-1313.
    • (2016) J Thromb Haemost. , vol.14 , pp. 1308-1313
    • Martin, K.1    Beyer-Westendorf, J.2    Davidson, B.L.3
  • 25
    • 84884336961 scopus 로고    scopus 로고
    • Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: A pooled analysis of the Einstein-DVT and PE randomized studies
    • Prins MH, Lensing AW, Bauersachs R, et al. Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: A pooled analysis of the EINSTEIN-DVT and PE randomized studies. Thromb J. 2013; 11: 21.
    • (2013) Thromb J. , vol.11 , pp. 21
    • Prins, M.H.1    Lensing, A.W.2    Bauersachs, R.3
  • 26
    • 84859745039 scopus 로고    scopus 로고
    • Anticoagulation therapy. Dabigatran and risk of myocardial infarction
    • Eikelboom JW, Weitz JI. Anticoagulation therapy. Dabigatran and risk of myocardial infarction. Nat Rev Cardiol. 2012; 9: 260-262.
    • (2012) Nat Rev Cardiol. , vol.9 , pp. 260-262
    • Eikelboom, J.W.1    Weitz, J.I.2
  • 27
    • 84896117299 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: A meta-analysis of randomised trials
    • Ruff CT, Giugliano RP, Braunwald E, et al. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: A meta-analysis of randomised trials. Lancet. 2014; 383: 955-962.
    • (2014) Lancet. , vol.383 , pp. 955-962
    • Ruff, C.T.1    Giugliano, R.P.2    Braunwald, E.3
  • 28
    • 84924034859 scopus 로고    scopus 로고
    • Cardiovascular, bleeding, and mortality risks in elderly medicare patients treated with dabigatran or warfarin for nonvalvular atrial fibrillation
    • Graham DJ, Reichman ME, Wernecke M, et al. Cardiovascular, bleeding, and mortality risks in elderly medicare patients treated with dabigatran or warfarin for nonvalvular atrial fibrillation. Circulation. 2015; 131: 157-164.
    • (2015) Circulation. , vol.131 , pp. 157-164
    • Graham, D.J.1    Reichman, M.E.2    Wernecke, M.3
  • 29
    • 84878368262 scopus 로고    scopus 로고
    • Management of antithrombotic therapy in patients undergoing invasive procedures
    • Baron TH, Kamath PS, McBane RD. Management of antithrombotic therapy in patients undergoing invasive procedures. N Engl J Med. 2013; 368: 2113-2124.
    • (2013) N Engl J Med. , vol.368 , pp. 2113-2124
    • Baron, T.H.1    Kamath, P.S.2    McBane, R.D.3
  • 30
    • 84994324445 scopus 로고    scopus 로고
    • Accessed August 31
    • Boehringer-Ingelheim. Product Monograph: Pradaxa 2016. Available from: http://www.boehringeringelheim.ca/content/dam/internet/opu/ca-EN/documents/humanhealth/product-monograph/PradaxaPMEN.pdf. Accessed August 31, 2016.
    • (2016) Product Monograph: Pradaxa 2016
  • 31
    • 84994343561 scopus 로고    scopus 로고
    • Accessed August 31
    • Bayer. Product Monograph: Xarelto 2016. Available from: http://www. bayer.ca/omr/online/xarelto-pm-en.pdf. Accessed August 31, 2016.
    • (2016) Product Monograph: Xarelto 2016
  • 32
    • 84994359910 scopus 로고    scopus 로고
    • Accessed August 31
    • Pfizer. Product Monograph: Eliquis 2016. Available from: http://www.pfizer.ca/sites/g/files/g10028126/f/201607/ELIQUIS-PM-184464-16June2016-E-marketed.pdf. Accessed August 31, 2016.
    • (2016) Product Monograph: Eliquis 2016
  • 33
  • 34
    • 84890689245 scopus 로고    scopus 로고
    • New oral anticoagulants and regional anaesthesia
    • Benzon HT, Avram MJ, Green D, et al. New oral anticoagulants and regional anaesthesia. Br J Anaesth. 2013; 111: SI96-SI113.
    • (2013) Br J Anaesth. , vol.111 , pp. SI96-SI113
    • Benzon, H.T.1    Avram, M.J.2    Green, D.3
  • 35
    • 84948737936 scopus 로고    scopus 로고
    • Practical management of bleeding in patients receiving non-Vitamin K antagonist oral anticoagulants
    • Weitz JI, Pollack CV Jr. Practical management of bleeding in patients receiving non-vitamin K antagonist oral anticoagulants. Thromb Haemost. 2015; 114: 1113-1126.
    • (2015) Thromb Haemost. , vol.114 , pp. 1113-1126
    • Weitz, J.I.1    Pollack, C.V.2
  • 36
    • 84969567323 scopus 로고    scopus 로고
    • Coagulation assessment with the new generation of oral anticoagulants
    • Pollack CV Jr. Coagulation assessment with the new generation of oral anticoagulants. Emerg Med J. 2016; 33: 423-340.
    • (2016) Emerg Med J. , vol.33 , pp. 423-440
    • Pollack, C.V.1
  • 37
    • 84975770227 scopus 로고    scopus 로고
    • When and how to use antidotes for the reversal of direct oral anticoagulants: Guidance from the SSC of the ISTH
    • Levy JH, Ageno W, Chan NC, et al. When and how to use antidotes for the reversal of direct oral anticoagulants: guidance from the SSC of the ISTH. J Thromb Haemost. 2016; 14: 623-627.
    • (2016) J Thromb Haemost. , vol.14 , pp. 623-627
    • Levy, J.H.1    Ageno, W.2    Chan, N.C.3
  • 38
    • 84953333508 scopus 로고    scopus 로고
    • Idarucizumab: The antidote for reversal of dabigatran
    • Eikelboom JW, Quinlan DJ, van Ryn J, et al. Idarucizumab: The antidote for reversal of dabigatran. Circulation. 2015; 132: 2412-2422.
    • (2015) Circulation. , vol.132 , pp. 2412-2422
    • Eikelboom, J.W.1    Quinlan, D.J.2    Van Ryn, J.3
  • 40
    • 84878460192 scopus 로고    scopus 로고
    • A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa
    • Lu G, DeGuzman FR, Hollenbach SJ, et al. A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa. Nat Med. 2013; 19: 446-351.
    • (2013) Nat Med. , vol.19 , pp. 446-451
    • Lu, G.1    DeGuzman, F.R.2    Hollenbach, S.J.3
  • 41
    • 84885198658 scopus 로고    scopus 로고
    • The real decoy: An antidote for factor Xa-directed anticoagulants
    • Yeh CH, Fredenburgh JC, Weitz JI. The real decoy: an antidote for factor Xa-directed anticoagulants. Circ Res. 2013; 113: 954-957.
    • (2013) Circ Res. , vol.113 , pp. 954-957
    • Yeh, C.H.1    Fredenburgh, J.C.2    Weitz, J.I.3
  • 42
    • 84950127054 scopus 로고    scopus 로고
    • Andexanet alfa for the reversal of factor Xa inhibitor activity
    • Siegal DM, Curnutte JT, Connolly SJ, et al. Andexanet alfa for the reversal of factor Xa inhibitor activity. N Engl J Med. 2015; 373: 2413-2424.
    • (2015) N Engl J Med. , vol.373 , pp. 2413-2424
    • Siegal, D.M.1    Curnutte, J.T.2    Connolly, S.J.3
  • 43
    • 84988893659 scopus 로고    scopus 로고
    • Andexanet alfa for acute major bleeding associated with factor Xa inhibitors
    • Epub ahead of print
    • Connolly SJ, Milling TJ Jr, Eikelboom JW, et al. Andexanet alfa for acute major bleeding associated with factor Xa inhibitors. N Engl J Med. 2016. [Epub ahead of print].
    • (2016) N Engl J Med.
    • Connolly, S.J.1    Milling, T.J.2    Eikelboom, J.W.3
  • 44
    • 84938687146 scopus 로고    scopus 로고
    • Nonclinical safety assessment of PER977: A small molecule reversal agent for new oral anticoagulants and heparins
    • Sullivan DW Jr, Gad SC, Laulicht B, et al. Nonclinical safety assessment of PER977: A small molecule reversal agent for new oral anticoagulants and heparins. Int J Toxicol. 2015; 34: 308-317.
    • (2015) Int J Toxicol. , vol.34 , pp. 308-317
    • Sullivan, D.W.1    Gad, S.C.2    Laulicht, B.3
  • 45
    • 84915821873 scopus 로고    scopus 로고
    • Use of PER977 to reverse the anticoagulant effect of edoxaban
    • Ansell JE, Bakhru SH, Laulicht BE, et al. Use of PER977 to reverse the anticoagulant effect of edoxaban. N Engl J Med. 2014; 371: 2141-2142.
    • (2014) N Engl J Med. , vol.371 , pp. 2141-2142
    • Ansell, J.E.1    Bakhru, S.H.2    Laulicht, B.E.3
  • 46
    • 84979697600 scopus 로고    scopus 로고
    • Ciraparantag safely and completely reverses the anticoagulant effects of low molecular weight heparin
    • Ansell JE, Laulicht BE, Bakhru SH, et al. Ciraparantag safely and completely reverses the anticoagulant effects of low molecular weight heparin. Thromb Res. 2016.
    • (2016) Thromb Res.
    • Ansell, J.E.1    Laulicht, B.E.2    Bakhru, S.H.3
  • 47
    • 84931325490 scopus 로고    scopus 로고
    • Management of the bleeding patient receiving new oral anticoagulants: A role for prothrombin complex concentrates
    • Baumann Kreuziger LM, Keenan JC, Morton CT, et al. Management of the bleeding patient receiving new oral anticoagulants: A role for prothrombin complex concentrates. Biomed Res Int. 2014; 2014: 583794.
    • (2014) Biomed Res Int. , vol.2014 , pp. 583794
    • Baumann Kreuziger, L.M.1    Keenan, J.C.2    Morton, C.T.3
  • 48
    • 84923903585 scopus 로고    scopus 로고
    • Edoxaban effects on bleeding following punch biopsy and reversal by a 4-factor prothrombin complex concentrate
    • Zahir H, Brown KS, Vandell AG, et al. Edoxaban effects on bleeding following punch biopsy and reversal by a 4-factor prothrombin complex concentrate. Circulation. 2015; 131: 82-90.
    • (2015) Circulation. , vol.131 , pp. 82-90
    • Zahir, H.1    Brown, K.S.2    Vandell, A.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.