High attenuation areas on chest computed tomography in communitydwelling adults: The MESA study

European Respiratory Journal

Volumn 48, Issue 5, 2016, Pages 1442-1452

  Podolanczuk, Anna J ^a   Oelsner, Elizabeth C ^a   Barr, R Graham ^a   Hoffman, Eric A ^b   Armstrong, Hilary F ^a   Austin, John H M ^a   Basner, Robert C ^a   Bartels, Matthew N ^c   Christie, Jason D ^d   Enright, Paul L ^e   Gochuico, Bernadette R ^f   Stukovsky, Karen Hinckley ^g   Kaufman, Joel D ^g   Nath, P Hrudaya ^h   Newell, John D ^b   Palmer, Scott M ⁱ   Rabinowitz, Dan ^j   Raghu, Ganesh ^g   Sell, Jessica L ^a   Sieren, Jered ^k   Sonavane, Sushil K ^h   Tracy, Russell P ^l   Watts, Jubal R ^h   Williams, Kayleen ^g   Kawut, Steven M ^m   Lederer, David J ^a   more..

^a Department of Medicine   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF ARIZONA   (United States)

^f NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^g UNIVERSITY OF WASHINGTON   (United States)

^h University of Alabama at Birmingham   (United States)

ⁱ DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^j Columbia University ^*  (United States)

^k VIDA Diagnostics Inc   (United States)

^l UNIVERSITY OF VERMONT   (United States)

^m UNIVERSITY OF PENNSYLVANIA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 6; MATRILYSIN; SURFACTANT PROTEIN A; BIOLOGICAL MARKER; IL6 PROTEIN, HUMAN; MMP7 PROTEIN, HUMAN;

ADULT; AFRICAN AMERICAN; AGED; ARTICLE; ASIAN; CAUCASIAN; COHORT ANALYSIS; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; FOLLOW UP; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HISPANIC; HUMAN; INTERSTITIAL LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; MORTALITY; POPULATION RESEARCH; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; WALKING; BLOOD; DIAGNOSTIC IMAGING; EXERCISE; FIBROSIS; INFLAMMATION; LUNG; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PROCEDURES; PROPORTIONAL HAZARDS MODEL; SMOKING; SPIROMETRY; THORAX RADIOGRAPHY; X-RAY COMPUTED TOMOGRAPHY;

ADULT; AGED; BIOMARKERS; C-REACTIVE PROTEIN; EXERCISE; EXTRACELLULAR MATRIX; FEMALE; FIBROSIS; HUMANS; INFLAMMATION; INTERLEUKIN-6; LUNG; LUNG DISEASES, INTERSTITIAL; MALE; MATRIX METALLOPROTEINASE 7; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; RADIOGRAPHY, THORACIC; SMOKING; SPIROMETRY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84994220086     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/13993003.00129-2016     Document Type: Article

References (55)

1. Selman M, Pardo A. Alveolar epithelial cell disintegrity and subsequent activation: a key process in pulmonary fibrosis. Am J Respir Crit Care Med 2012; 186: 119-121.
2. Zoz DF, Lawson WE, Blackwell TS. Idiopathic pulmonary fibrosis: a disorder of epithelial cell dysfunction. Am J Med Sci 2011; 341: 435-438.
3. Rosas IO, Ren P, Avila NA, et al. Early interstitial lung disease in familial pulmonary fibrosis. Am J Respir Crit Care Med 2007; 176: 698-705.
4. Doyle TJ, Hunninghake GM, Rosas IO. Subclinical interstitial lung disease: why you should care. Am J Respir Crit Care Med 2012; 185: 1147-1153.
5. Kropski JA, Pritchett JM, Zoz DF, et al. Extensive phenotyping of individuals at-risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease. Am J Respir Crit Care Med 2014; 191: 417-426.
6. Washko GR, Hunninghake GM, Fernandez IE, et al. Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med 2011; 364: 897-906.
7. Doyle TJ, Washko GR, Fernandez IE, et al. Interstitial lung abnormalities and reduced exercise capacity. Am J Respir Crit Care Med 2012; 185: 756-762.
8. Hunninghake GM, Hatabu H, Okajima Y, et al. MUC5B promoter polymorphism and interstitial lung abnormalities. N Engl J Med 2013; 368: 2192-2200.
9. Putman RK, Hatabu H, Araki T, et al. Association between interstitial lung abnormalities and all-cause mortality. JAMA 2016; 315: 672-681.
10. Lederer DJ, Enright PL, Kawut SM, et al. Cigarette smoking is associated with subclinical parenchymal lung disease: the Multi-Ethnic Study of Atherosclerosis (MESA)-lung study. Am J Respir Crit Care Med 2009; 180: 407-414.
11. Kliment CR, Araki T, Doyle TJ, et al. A comparison of visual and quantitative methods to identify interstitial lung abnormalities. BMC Pulm Med 2015; 15: 134.
12. Gauldie J, Richards C, Harnish D, et al. Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proc Natl Acad Sci USA 1987; 84: 7251-7255.
13. Kushner I, Feldmann G. Control of the acute phase response. Demonstration of C-reactive protein synthesis and secretion by hepatocytes during acute inflammation in the rabbit. J Exp Med 1978; 148: 466-477.
14. Greene KE, Wright JR, Steinberg KP, et al. Serial changes in surfactant-associated proteins in lung and serum before and after onset of ARDS. Am J Respir Crit Care Med 1999; 160: 1843-1850.
15. Ohnishi H, Yokoyama A, Kondo K, et al. Comparative study of KL-6, surfactant protein-A, surfactant protein-D, and monocyte chemoattractant protein-1 as serum markers for interstitial lung diseases. Am J Respir Crit Care Med 2002; 165: 378-381.
16. Greene KE, King TE Jr, Kuroki Y, et al. Serum surfactant proteins-A and -D as biomarkers in idiopathic pulmonary fibrosis. Eur Respir J 2002; 19: 439-446.
17. Kinder BW, Brown KK, McCormack FX Jr, et al. Serum surfactant protein-A is a strong predictor of early mortality in idiopathic pulmonary fibrosis. Chest 2009; 135: 1557-1563.
18. Richards TJ, Kaminski N, Baribaud F, et al. Peripheral blood proteins predict mortality in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2012; 185: 67-76.
19. Rosas IO, Richards TJ, Konishi K, et al. MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis. PLoS Med 2008; 5: e93.
20. Zuo F, Kaminski N, Eugui E, et al. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc Natl Acad Sci USA 2002; 99: 6292-6297.
21. Bild DE, Bluemke DA, Burke GL, et al. Multi-ethnic study of atherosclerosis: objectives and design. Am J Epidemiol 2002; 156: 871-881.
22. Carr JJ, Nelson JC, Wong ND, et al. Calcified coronary artery plaque measurement with cardiac CT in population-based studies: standardized protocol of Multi-Ethnic Study of Atherosclerosis (MESA) and Coronary Artery Risk Development in Young Adults (CARDIA) study. Radiology 2005; 234: 35-43.
23. Hoffman EA, Jiang R, Baumhauer H, et al. Reproducibility and validity of lung density measures from cardiac CT Scans-The Multi-Ethnic Study of Atherosclerosis (MESA) Lung Study. Acad Radiol 2009; 16: 689-699.
24. Gevenois PA, de Maertelaer V, De Vuyst P, et al. Comparison of computed density and macroscopic morphometry in pulmonary emphysema. Am J Respir Crit Care Med 1995; 152: 653-657.
25. Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J 2005; 26: 319-338.
26. Hankinson JL, Kawut SM, Shahar E, et al. Performance of American Thoracic Society-recommended spirometry reference values in a multiethnic sample of adults: the multi-ethnic study of atherosclerosis (MESA) lung study. Chest 2010; 137: 138-145.
27. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med 2002; 166: 111-117.
28. Couper D, LaVange LM, Han M, et al. Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Thorax 2014; 69: 491-494.
29. Hoffman EA, Ahmed FS, Baumhauer H, et al. Variation in the percent of emphysema-like lung in a healthy, nonsmoking multiethnic sample. The MESA lung study. Ann Am Thorac Soc 2014; 11: 898-907.
30. Washko GR, Lynch DA, Matsuoka S, et al. Identification of early interstitial lung disease in smokers from the COPDGene Study. Acad Radiol 2010; 17: 48-53.
31. Oelsner EC, Hoffman EA, Folsom AR, et al. Association between emphysema-like lung on cardiac computed tomography and mortality in persons without airflow obstruction: a cohort study. Ann Intern Med 2014; 161: 863-873.
32. Kolb M, Margetts PJ, Anthony DC, et al. Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis. J Clin Invest 2001; 107: 1529-1536.
33. Zhang H, Neuhöfer P, Song L, et al. IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality. J Clin Invest 2013; 123: 1019-1031.
34. Garcia-Rio F, Miravitlles M, Soriano JB, et al. Systemic inflammation in chronic obstructive pulmonary disease: a population-based study. Respir Res 2010; 11: 63.
35. Hoeboer SH, Groeneveld AB, van der Heijden M, et al. Serial inflammatory biomarkers of the severity, course and outcome of late onset acute respiratory distress syndrome in critically ill patients with or at risk for the syndrome after new-onset fever. Biomark Med 2015; 9: 605-616.
36. Shahar I, Fireman E, Topilsky M, et al. Effect of IL-6 on alveolar fibroblast proliferation in interstitial lung diseases. Clin Immunol Immunopathol 1996; 79: 244-251.
37. Chang SS, Vaz Fragoso CA, Van Ness PH, et al. Association between combined interleukin-6 and C-reactive protein levels and pulmonary function in older women: results from the Women's Health and Aging Studies I and II. J Am Geriatr Soc 2011; 59: 113-119.
38. Thorleifsson SJ, Margretardottir OB, Gudmundsson G, et al. Chronic airflow obstruction and markers of systemic inflammation: results from the BOLD study in Iceland. Respir Med 2009; 103: 1548-1553.
39. Lee BT, Ahmed FA, Hamm LL, et al. Association of C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 with chronic kidney disease. BMC Nephrol 2015; 16: 77.
40. Czarkowska-Paczek B, Bartlomiejczyk I, Gabrys T, et al. Lack of relationship between interleukin-6 and CRP levels in healthy male athletes. Immunol Lett 2005; 99: 136-140.
41. Bermudez EA, Rifai N, Buring J, et al. Interrelationships among circulating interleukin-6, C-reactive protein, and traditional cardiovascular risk factors in women. Arterioscler Thromb Vasc Biol 2002; 22: 1668-1673.
42. Gharib SA, Altemeier WA, Van Winkle LS, et al. Matrix metalloproteinase-7 coordinates airway epithelial injury response and differentiation of ciliated cells. Am J Respir Cell Mol Biol 2013; 48: 390-396.
43. Villar J, Cabrera-Benítez NE, Ramos-Nuez A, et al. Early activation of pro-fibrotic WNT5A in sepsis-induced acute lung injury. Crit Care 2014; 18: 568.
44. Dunsmore SE, Saarialho-Kere UK, Roby JD, et al. Matrilysin expression and function in airway epithelium. J Clin Invest 1998; 102: 1321-1331.
45. Shin KE, Chung MJ, Jung MP, et al. Quantitative computed tomographic indexes in diffuse interstitial lung disease: correlation with physiologic tests and computed tomography visual scores. J Comput Assist Tomogr 2011; 35: 266-271.
46. Matsuoka S, Yamashiro T, Matsushita S, et al. Quantitative CT evaluation in patients with combined pulmonary fibrosis and emphysema: correlation with pulmonary function. Acad Radiol 2015; 22: 626-631.
47. Matsuoka S, Yamashiro T, Matsushita S, et al. Morphological disease progression of combined pulmonary fibrosis and emphysema: comparison with emphysema alone and pulmonary fibrosis alone. J Comput Assist Tomogr 2015; 39: 153-159.
48. Maldonado F, Moua T, Rajagopalan S, et al. Automated quantification of radiological patterns predicts survival in idiopathic pulmonary fibrosis. Eur Respir J 2014; 43: 204-212.
49. Noor NM, Than JC, Rijal OM, et al. Automatic lung segmentation using control feedback system: morphology and texture paradigm. J Med Syst 2015; 39: 22.
50. Moon JW, Bae JP, Lee HY, et al. Perfusion- and pattern-based quantitative CT indexes using contrast-enhanced dual-energy computed tomography in diffuse interstitial lung disease: relationships with physiologic impairment and prediction of prognosis. Eur Radiol 2016; 26: 1368-1377.
51. Depeursinge A, Chin AS, Leung AN, et al. Automated classification of usual interstitial pneumonia using regional volumetric texture analysis in high-resolution computed tomography. Invest Radiol 2015; 50: 261-267.
52. Xu Y, van Beek EJ, Hwanjo Y, et al. Computer-aided classification of interstitial lung diseases via MDCT: 3D adaptive multiple feature method (3D AMFM). Acad Radiol 2006; 13: 969-978.
53. Lederer DJ. Secondary prevention of idiopathic pulmonary fibrosis: catching the horse still in the barn. Am J Respir Crit Care Med 2012; 185: 697-699.
54. Barr RG, Bluemke DA, Ahmed FS, et al. Percent emphysema, airflow obstruction, and impaired left ventricular filling. N Engl J Med 2010; 362: 217-227.
55. Chapman KR, Burdon JG, Piitulainen E, et al. Intravenous augmentation treatment and lung density in severe alpha1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial. Lancet 2015; 386: 360-368.