Using Clinical Characteristics to Identify Which Patients With Major Depressive Disorder Have a Higher Genetic Load for Three Psychiatric Disorders

Biological Psychiatry

Volumn 81, Issue 4, 2017, Pages 316-324

  Verduijn, Judith ^a,b   Milaneschi, Yuri ^a,b   Peyrot, Wouter J ^a,b   Hottenga, Jouke Jan ^a,b,c   Abdellaoui, Abdel ^c   de Geus, Eco J C ^b,c   Smit, Johannes H ^a,b   Breen, Gerome ^d,e   Lewis, Cathryn M ^d   Boomsma, Dorret I ^c   Beekman, Aartjan T F ^a,b   Penninx, Brenda W J H ^a,b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

^e KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Clinical characteristics; Genetic load; Genetics; Heterogeneity; Major depressive disorder; Replication; Staging

Indexed keywords

ADULT; AGED; ARTICLE; BIPOLAR DISORDER; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE DURATION; DISEASE SEVERITY; FAMILY HISTORY; FEMALE; GENETIC ASSOCIATION; GENETIC LOAD; GENETIC RISK; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MAXIMUM LIKELIHOOD METHOD; MENTAL PATIENT; ONSET AGE; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; DEPRESSIVE DISORDER, MAJOR; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; PSYCHOLOGICAL RATING SCALE; RISK FACTOR;

ADULT; AGE OF ONSET; BIPOLAR DISORDER; DEPRESSIVE DISORDER, MAJOR; FEMALE; GENETIC LOAD; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PSYCHIATRIC STATUS RATING SCALES; RISK FACTORS; SCHIZOPHRENIA;

EID: 84994121042     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2016.05.024     Document Type: Article

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