Complicated community acquired pneumonia in childhood: Different types, clinical course, and outcome

Pediatric Pulmonology

Volumn 52, Issue 2, 2017, Pages 247-254

  Erlichman, Ira ^a   Breuer, Oded ^a   Shoseyov, David ^a   Cohen Cymberknoh, Malena ^a   Koplewitz, Benjamin ^a   Averbuch, Diana ^a   Erlichman, Matti ^b   Picard, Elie ^b   Kerem, Eitan ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b SHAARE ZEDEK MEDICAL CENTER   (Israel)

Author keywords

empyema; necrotizing pneumonia; para pneumonic effusion; pediatric community acquired complicated pneumonia

Indexed keywords

ANTIBIOTIC THERAPY; ARTICLE; BACTERIUM ISOLATE; CHILD; CHILDHOOD; CLINICAL EFFECTIVENESS; CLINICAL PROTOCOL; COMMUNITY ACQUIRED PNEUMONIA; DEMOGRAPHY; DISEASE SEVERITY; EMPYEMA; FEMALE; FIBRINOLYSIS; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; LENGTH OF STAY; LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MORBIDITY; NECROTIZING PNEUMONIA; NONHUMAN; OUTCOME ASSESSMENT; PARA PNEUMONIC EFFUSION; PEDIATRIC COMMUNITY ACQUIRED COMPLICATED PNEUMONIA; PRESCHOOL CHILD; RETROSPECTIVE STUDY; STREPTOCOCCUS GROUP A; STREPTOCOCCUS PNEUMONIAE; ADOLESCENT; COMMUNITY-ACQUIRED INFECTIONS; COMPLICATION; EMPYEMA, PLEURAL; INCIDENCE; INFANT; ISRAEL; MICROBIOLOGY; PLEURAL EFFUSION; PNEUMONIA; PNEUMONIA, NECROTIZING; PNEUMONIA, PNEUMOCOCCAL; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES; SURVIVAL RATE;

ANTIINFECTIVE AGENT;

ADOLESCENT; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; COMMUNITY-ACQUIRED INFECTIONS; EMPYEMA, PLEURAL; FEMALE; HOSPITALIZATION; HUMANS; INCIDENCE; INFANT; ISRAEL; MALE; PLEURAL EFFUSION; PNEUMONIA; PNEUMONIA, NECROTIZING; PNEUMONIA, PNEUMOCOCCAL; RETROSPECTIVE STUDIES; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES; SURVIVAL RATE;

EID: 84994108663     PISSN: 87556863     EISSN: 10990496     Source Type: Journal    
DOI: 10.1002/ppul.23523     Document Type: Article

References (40)

1. McIntosh K. Community-acquired pneumonia in children. N Engl J Med 2002; 346:429–437.
2. Sawicki GS, Lu FL, Valim C, Cleveland RH, Colin AA. Necrotising pneumonia is an increasingly detected complication of pneumonia in children. Eur Respir J 2008; 31:1285–1291.
3. Strachan R, Jaffe A. Australian Research Network in E. Assessment of the burden of paediatric empyema in Australia. J Paediatr Child Health 2009; 45:431–436.
4. Bekri H, Cohen R, Varon E, Madhi F, Gire R, Guillot F, Delacourt C. [Streptococcus pneumoniae serotypes involved in children with pleural empyemas in France]. Arch Pediatr 2007; 14:239–243.
5. Fletcher M, Leeming J, Cartwright K, Finn A. South West of England Invasive Community Acquired Infection Study G. Childhood empyema: limited potential impact of 7-valent pneumococcal conjugate vaccine. Pediatr Infect Dis J 2006; 25:559–560.
6. Tan TQ, Mason EO, Jr., Wald ER, Barson WJ, Schutze GE, Bradley JS, Givner LB, Yogev R, Kim KS, Kaplan SL. Clinical characteristics of children with complicated pneumonia caused by Streptococcus pneumoniae. Pediatrics 2002; 110:1–6.
7. Byington CL, Spencer LY, Johnson TA, Pavia AT, Allen D, Mason EO, Kaplan S, Carroll KC, Daly JA, Christenson JC, et al. An epidemiological investigation of a sustained high rate of pediatric parapneumonic empyema: risk factors and microbiological associations. Clin Infect Dis 2002; 34:434–440.
8. Schultz KD, Fan LL, Pinsky J, Ochoa L, Smith EO, Kaplan SL, Brandt ML. The changing face of pleural empyemas in children: epidemiology and management. Pediatrics 2004; 113:1735–1740.
9. Playfor SD, Smyth AR, Stewart RJ. Increase in incidence of childhood empyema. Thorax 1997; 52:932.
10. Rees JH, Spencer DA, Parikh D, Weller P. Increase in incidence of childhood empyema in West Midlands, UK. Lancet 1997; 349:402.
11. Byington CL, Korgenski K, Daly J, Ampofo K, Pavia A, Mason EO. Impact of the pneumococcal conjugate vaccine on pneumococcal parapneumonic empyema. Pediatr Infect Dis J 2006; 25:250–254.
12. Li ST, Tancredi DJ. Empyema hospitalizations increased in US children despite pneumococcal conjugate vaccine. Pediatrics 2010; 125:26–33.
13. Hendrickson DJ, Blumberg DA, Joad JP, Jhawar S, McDonald RJ. Five-fold increase in pediatric parapneumonic empyema since introduction of pneumococcal conjugate vaccine. Pediatr Infect Dis J 2008; 27:1030–1032.
14. Spencer DA, Iqbal SM, Hasan A, Hamilton L. Empyema thoracis is still increasing in UK children. BMJ 2006; 332:1333.
15. Li ST, Gates RL. Primary operative management for pediatric empyema: decreases in hospital length of stay and charges in a national sample. Arch Pediatr Adolesc Med 2008; 162:44–48.
16. Shah SS, DiCristina CM, Bell LM, Ten Have T, Metlay JP. Primary early thoracoscopy and reduction in length of hospital stay and additional procedures among children with complicated pneumonia: results of a multicenter retrospective cohort study. Arch Pediatr Adolesc Med 2008; 162:675–681.
17. Chan W, Keyser–Gauvin E, Davis GM, Nguyen LT, Laberge JM. Empyema thoracis in children: a 26-year review of the Montreal Children's Hospital experience. J Pediatr Surg 1997; 32:870–872.
18. Shah SS, Ten Have TR, Metlay JP. Costs of treating children with complicated pneumonia: a comparison of primary video-assisted thoracoscopic surgery and chest tube placement. Pediatr Pulmonol 2010; 45:71–77.
19. Aziz A, Healey JM, Qureshi F, Kane TD, Kurland G, Green M, Hackam DJ. Comparative analysis of chest tube thoracostomy and video-assisted thoracoscopic surgery in empyema and parapneumonic effusion associated with pneumonia in children. Surg Infect (Larchmt) 2008; 9:317–323.
20. Cohen E, Weinstein M, Fisman DN. Cost-effectiveness of competing strategies for the treatment of pediatric empyema. Pediatrics 2008; 121:e1250–e1257.
21. Proesmans M, De Boeck K. Clinical practice: treatment of childhood empyema. Eur J Pediatr 2009; 168:639–645.
22. Kerem E, Bar Ziv Y, Rudenski B, Katz S, Kleid D, Branski D. Bacteremic necrotizing pneumococcal pneumonia in children. Am J Respir Crit Care Med 1994; 149:242–244.
23. Spencer DA, Thomas MF. Necrotising pneumonia in children. Paediatr Respir Rev 2014; 15:240–245; quiz 245.
24. Cevey-Macherel M, Galetto-Lacour A, Gervaix A, Siegrist CA, Bille J, Bescher-Ninet B, Kaiser L, Krahenbuhl JD, Gehri M. Etiology of community-acquired pneumonia in hospitalized children based on WHO clinical guidelines. Eur J Pediatr 2009; 168:1429–1436.
25. Langley JM, Kellner JD, Solomon N, Robinson JL, Le Saux N, McDonald J, Ulloa-Gutierrez R, Tan B, Allen U, Dobson S, et al. Empyema associated with community-acquired pneumonia: a Pediatric Investigator's Collaborative Network on Infections in Canada (PICNIC) study. BMC Infect Dis 2008; 8:129.
26. Elemraid MA, Thomas MF, Blain AP, Rushton SP, Spencer DA, Gennery AR, Clark JE, North East of England Pediatric Respiratory Infection Study Group Newcastle upon Tyne Risk factors for the development of pleural empyema in children. Pediatr Pulmonol 2015; 50:721–726.
27. Balfour-Lynn IM, Abrahamson E, Cohen G, Hartley J, King S, Parikh D, Spencer D, Thomson AH,. Urquhart Paediatric Pleural Diseases Subcommittee of the BTSSoCC. BTS guidelines for the management of pleural infection in children. Thorax 2005; 60:i1–21.
28. Bradley JS, Byington CL, Shah SS, Alverson B, Carter ER, Harrison C, Kaplan SL, Mace SE, McCracken GH, Jr., Moore MR, et al. Executive summary: the management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis 2011; 53:617–630.
29. Janda S, Swiston J. Intrapleural fibrinolytic therapy for treatment of adult parapneumonic effusions and empyemas: a systematic review and meta-analysis. Chest 2012; 142:401–411.
30. Singh M, Mathew JL, Chandra S, Katariya S, Kumar L. Randomized controlled trial of intrapleural streptokinase in empyema thoracis in children. Acta Paediatr 2004; 93:1443–1445.
31. Kelly MM, Shadman KA, Edmonson MB. Treatment trends and outcomes in US hospital stays of children with empyema. Pediatr Infect Dis J 2014; 33:431–436.
32. Mahant S, Cohen E, Weinstein M, Wadhwa A. Video-assisted thorascopic surgery vs chest drain with fibrinolytics for the treatment of pleural empyema in children: a systematic review of randomized controlled trials. Arch Pediatr Adolesc Med 2010; 164:201–203.
33. Sonnappa S, Cohen G, Owens CM, van Doorn C, Cairns J, Stanojevic S, Elliott MJ, Jaffe A. Comparison of urokinase and video-assisted thoracoscopic surgery for treatment of childhood empyema. Am J Respir Crit Care Med 2006; 174:221–227.
34. St Peter SD, Tsao K, Spilde TL, Keckler SJ, Harrison C, Jackson MA, Sharp SW, Andrews WS, Rivard DC, Morello FP, et al. Thoracoscopic decortication vs tube thoracostomy with fibrinolysis for empyema in children: a prospective, randomized trial. J Pediatr Surg 2009; 44:106–111; discussion 111.
35. Marhuenda C, Barcelo C, Fuentes I, Guillen G, Cano I, Lopez M, Hernandez F, Perez-Yarza EG, Matute JA, Garcia-Casillas MA, et al. Urokinase versus VATS for treatment of empyema: a randomized multicenter clinical trial. Pediatrics 2014; 134:e1301–e1307.
36. Kurt BA, Winterhalter KM, Connors RH, Betz BW, Winters JW. Therapy of parapneumonic effusions in children: video-assisted thoracoscopic surgery versus conventional thoracostomy drainage. Pediatrics 2006; 118:e547–e553.
37. Cobanoglu U, Sayir F, Bilici S, Melek M. Comparison of the methods of fibrinolysis by tube thoracostomy and thoracoscopic decortication in children with stage II and III empyema: a prospective randomized study. Pediatr Rep 2011; 3:e29.
38. Kang DW, Campos JR, Andrade Filho Lde O, Engel FC, Xavier AM, Macedo M, Meyer K. Thoracoscopy in the treatment of pleural empyema in pediatric patients. J Bras Pneumol 2008; 34:205–211.
39. Meier AH, Hess CB, Cilley RE. Complications and treatment failures of video-assisted thoracoscopic debridement for pediatric empyema. Pediatr Surg Int 2010; 26:367–371.
40. Chen JS, Huang KC, Chen YC, Hsu HH, Kuo SW, Huang PM, Lee JM, Lee YC. Pediatric empyema: outcome analysis of thoracoscopic management. J Thorac Cardiovasc Surg 2009; 137:1195–1199.