Chimpanzee Personality and the Arginine Vasopressin Receptor 1A Genotype

Behavior Genetics

Volumn 47, Issue 2, 2017, Pages 215-226

  Wilson, V A D ^a,b   Weiss, A ^a   Humle, T ^c   Morimura, N ^d   Udono, T ^d   Idani, G ^d   Matsuzawa, T ^d,e   Hirata, S ^d   Inoue Murayama, M ^d,f  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c UNIVERSITY OF KENT   (United Kingdom)

^d KYOTO UNIVERSITY   (Japan)

^e JAPAN MONKEY CENTRE   (Japan)

^f NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

Author keywords

Animal model; AVPR1a; Chimpanzee; Heritability; Personality; Vasopressin

Indexed keywords

ARGININE VASOPRESSIN RECEPTOR 1A; ARGIPRESSIN RECEPTOR; UNCLASSIFIED DRUG; ARGININE; VASOPRESSIN RECEPTOR;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; ATTENTION; BEHAVIOR GENETICS; DOMINANCE BEHAVIOR; EMOTIONALITY; EXTRAVERSION; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GUINEA; HERITABILITY; JAPAN; MALE; NEUROSIS; NONHUMAN; PAN TROGLODYTES; PERSONALITY; PHENOTYPE; SEX DIFFERENCE; SOCIAL BEHAVIOR; SOCIAL INTERACTION; AGGRESSION; ANIMAL; ANIMAL BEHAVIOR; ANIMAL MODEL; GENETIC POLYMORPHISM; GENETICS; METABOLISM; PSYCHOLOGY;

AGGRESSION; ALLELES; ANIMALS; ARGININE; BEHAVIOR, ANIMAL; GENOTYPE; MODELS, ANIMAL; PAN TROGLODYTES; PERSONALITY; PHENOTYPE; POLYMORPHISM, GENETIC; RECEPTORS, VASOPRESSIN; SOCIAL BEHAVIOR;

EID: 84994078712     PISSN: 00018244     EISSN: 15733297     Source Type: Journal    
DOI: 10.1007/s10519-016-9822-2     Document Type: Article

References (55)

1. Adams MJ, King JE, Weiss A (2012) The majority of genetic variation in orangutan personality and subjective well-being is nonadditive. Behav Genet 42:675–686
2. Almasy L, Blangero J (1998) Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62:1198–1211
3. Anestis SF, Webster TH, Kamilar JM et al (2014) AVPR1A variation in chimpanzees (Pan troglodytes): population differences and association with behavioral style. Int J Primatol 35:305–324
4. Bachner-Melman R, Zohar AH, Bacon-Shnoor N et al (2005) Link between vasopressin receptor AVPR1A promoter region microsatellites and measures of social behavior in humans. J Individ Differ 26:2–10
5. Bielsky IF, Hu SB, Szegda KL et al (2004) Profound impairment in social recognition and reduction in anxiety-like behavior in vasopressin V1a receptor knockout mice. Neuropsychopharmacology 29:483–493
6. Bouchard TJ Jr, Loehlin JC (2001) Genes, evolution, personality. Behav Genet 31:243–273
7. Brent LJ, Semple S, Maclarnon A et al (2014) Personality traits in rhesus macaques (Macaca mulatta) are heritable but do not predict reproductive output. Int J Primatol 35:188–209
8. Caldwell HK, Wersinger SR, Young WS (2008) The role of the vasopressin 1b receptor in aggression and other social behaviours. In: Neumann ID, Landgraf R (eds) Advances in vasopressin and oxytocin—from genes to behaviour to disease. Elsevier B. V, Amsterdam, pp 65–72
9. Chabris CF, Hebert BM, Benjamin DJ et al (2012) Most reported genetic associations with general intelligence are probably false positives. Psychol Sci 23:1314–1323
10. Costa PT Jr, McCrae RR (1995) Domains and facets: hierarchical personality assessment using the revised NEO personality inventory. J Personal Assess 64:21–50
11. Donaldson ZR, Kondrashov FA, Putnam A et al (2008) Evolution of a behavior-linked microsatellite-containing element in the 5′ flanking region of the primate AVPR1A gene. BMC Evol Biol 8:180
12. Ebstein RP, Israel S, Lerer E et al (2009) Arginine vasopressin and oxytocin modulate human social behavior. Ann N Y Acad Sci 1167:87–102
13. Ferris CF, Albers HE, Wesolowski SM et al (1984) Vasopressin injected into the hypothalamus triggers a stereotypic behavior in golden hamsters. Science 224:521–523
14. Ferris CF, Lu SF, Messenger T et al (2006) Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior. Pharmacol Biochem Behav 83:169–174
15. Fink S, Excoffier L, Heckel G (2006) Mammalian monogamy is not controlled by a single gene. Proc Natl Acad Sci USA 103:10956–10960
16. Freeman HD, Gosling SD (2010) Personality in nonhuman primates: a review and evaluation of past research. Am J Primatol 72:653–671
17. Goldberg LR (2006) Doing it all bass-ackwards: the development of hierarchical factor structures from the top down. J Res Personal 40:347–358
18. Graffelman J (2015) Exploring diallelic genetic markers: the HardyWeinberg package. J Stat Softw 64:1–22
19. Graffelman J, Morales-Camarena J (2008) Graphical tests for Hardy–Weinberg equilibrium based on the ternary plot. Hum Hered 65:77–84
20. Grimes LW, Harvey WR (1980) Estimation of genetic variances and covariances using symmetric differences squared. J Anim Sci 50:634–644
21. Guastella AJ, Kenyon AR, Alvares GA et al (2010) Intranasal arginine vasopressin enhances the encoding of happy and angry faces in humans. Biol Psychiatry 67:1220–1222
22. Hadfield J (2010) MCMC methods for multi-response generalized linear mixed models: the MCMCglmm R package. J Stat Softw 33:1–22
23. Hammock EAD, Young LJ (2005) Microsatellite instability generates diversity in brain and sociobehavioral traits. Science 308:1630–1634
24. Haram M, Tesli M, Dieset I et al (2014) An attempt to identify single nucleotide polymorphisms contributing to possible relationships between personality traits and oxytocin-related genes. Neuropsychobiology 69:25–30
25. Hong KW, Matsukawa R, Hirata Y et al (2009) Allele distribution and effect on reporter gene expression of vasopressin receptor gene (AVPR1a)-linked VNTR in primates. J Neural Transm 116:535–538
26. Hopkins WD, Donaldson ZR, Young LJ (2012) A polymorphic indel containing the RS3 microsatellite in the 5′ flanking region of the vasopressin V1a receptor gene is associated with chimpanzee (Pan troglodytes) personality. Genes Brain Behav 11:552–558
27. Hopkins WD, Keebaugh AC, Reamer LA et al (2014) Genetic influences on receptive joint attention in chimpanzees (Pan troglodytes). Sci Rep 4:3774
28. King JE, Figueredo AJ (1997) The five-factor model plus dominance in chimpanzee personality. J Res Personal 31:257–271
29. King JE, Weiss A (2011) Personality from the perspective of a primatologist. In: Weiss A, King JE, Murray L (eds) Personality and temperament in nonhuman primates. Springer, New York, pp 77–99
30. King JE, Weiss A, Farmer KH (2005) A chimpanzee (Pan troglodytes) analogue of cross-national generalization of personality structure: zoological parks and an African sanctuary. J Personal 73:389–410
31. Knafo A, Israel S, Darvasi A et al (2008) Individual differences in allocation of funds in the dictator game associated with length of the arginine vasopressin 1a receptor RS3 promoter region and correlation between RS3 length and hippocampal mRNA. Genes Brain Behav 7:266–275
32. Kruuk LEB (2004) Estimating genetic parameters in natural populations using the ‘animal model’. Philos Trans R Soc B Biol Sci 359:873–890
33. Latzman RD, Hopkins WD, Keebaugh AC et al (2014) Personality in chimpanzees (Pan troglodytes): exploring the hierarchical structure and associations with the vasopressin V1A receptor gene. PLoS One 9:e95741
34. Latzman RD, Freeman HD, Schapiro SJ et al (2015) The contribution of genetics and early rearing experiences to hierarchical personality dimensions in chimpanzees (Pan troglodytes). J Personal Soc Psychol 109:889–900
35. Nair HP, Young LJ (2006) Vasopressin and pair-bond formation: genes to brain to behavior. Physiology 21:146–152
36. O’Connor CM, Marsh-Rollo SE, Ghio SC et al (2015) Is there convergence in the molecular pathways underlying the repeated evolution of sociality in African cichlids? Horm Behav 75:160–168
37. O’Hara RB, Cano JM, Ovaskainen O et al (2008) Bayesian approaches in evolutionary quantitative genetics. J Evol Biol 21:949–957
38. Pappa I, St Pourcain B, Benke K et al (2016) A genome-wide approach to children’s aggressive behavior: the EAGLE consortium. Am J Med Genet Part B Neuropsychiatr Genet 171:562–572
39. Pederson AK, King JE, Landau VI (2005) Chimpanzee (Pan troglodytes) personality predicts behavior. J Res Pers 39:534–549
40. R Core Team (2015) R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna
41. Reddon AR, O’Connor CM, Marsh-Rollo SE et al (2015) Brain nonapeptide levels are related to social status and affiliative behaviour in a cooperatively breeding cichlid fish. R Soc Open Sci 2:140072
42. Reif A, Lesch K-P (2003) Toward a molecular architecture of personality. Behav Brain Res 139:1–20
43. Rilling JK, DeMarco AC, Hackett PD et al (2012) Effects of intranasal oxytocin and vasopressin on cooperative behavior and associated brain activity in men. Psychoneuroendocrinology 37:447–461
44. Rosso L, Keller L, Kaessmann H et al (2008) Mating system and avpr1a promoter variation in primates. Biol Lett 4:375–378
45. Staes N, Koski SE, Helsen P et al (2015) Chimpanzee sociability is associated with vasopressin (Avpr1a) but not oxytocin receptor gene (OXTR) variation. Horm Behav 75:84–90
46. Suomi SJ (2006) Risk, resilience, and gene x environment interactions in rhesus monkeys. Ann N Y Acad Sci 1094:52–62
47. Tabor HK, Risch NJ, Myers RM (2002) Candidate-gene approaches for studying complex genetic traits: practical considerations. Nat Rev Genet 3:1–7
48. Thibonnier M, Graves MK, Wagner MS et al (2000) Study of V(1)-vascular vasopressin receptor gene microsatellite polymorphisms in human essential hypertension. J Mol Cell Cardiol 32:557–564
49. Walum H, Westberg L, Henningsson S et al (2008) Genetic variation in the vasopressin receptor 1a gene (AVPR1A) associates with pair-bonding behavior in humans. Proc Natl Acad Sci USA 105:14153–14156
50. Weiss A, King JE, Figueredo AJ (2000) The heritability of personality factors in chimpanzees (Pan troglodytes). Behav Genet 30:213–221
51. Weiss A, King JE, Perkins L (2006) Personality and subjective well-being in orangutans (Pongo pygmaeus and Pongo abelii). J Personal Soc Psychol 90:501–511
52. Weiss A, King JE, Hopkins WD (2007) A cross-setting study of chimpanzee (Pan troglodytes) personality structure and development: zoological parks and Yerkes National Primate Research Center. Am J Primatol 69:1264–1277
53. Weiss A, Inoue-Murayama M, Hong KW et al (2009) Assessing chimpanzee personality and subjective well-being in Japan. Am J Primatol 71:283–292
54. Wersinger SR, Ginns EI, O’Carroll A-M et al (2002) Vasopressin V1b receptor knockout reduces aggressive behavior in male mice. Mol Psychiatry 7:975–984
55. Zink CF, Stein JL, Kempf L et al (2010) Vasopressin modulates medial prefrontal cortex–amygdala circuitry during emotion processing in humans. J Neurosci 30:7017–7022