Radio-Frequency (rf) Confinement in Ion Mobility Spectrometry: Apparent Mobilities and Effective Temperatures

Journal of the American Society for Mass Spectrometry

Volumn 27, Issue 12, 2016, Pages 2054-2063

  Allen, Samuel J ^a   Bush, Matthew F ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Effective temperature; Ion mobility mass spectrometry; Ion mobility spectrometry; Native mass spectrometry

Indexed keywords

ION MOBILITY SPECTROMETERS; MASS SPECTROMETRY; RADIO WAVES; SPECTROMETRY; TEMPERATURE;

EFFECTIVE POTENTIAL-APPROXIMATION; EFFECTIVE TEMPERATURE; ELECTRODE DIMENSIONS; ELECTROSTATIC DRIFT; ION MOBILITY SPECTROMETRY; ION MOBILITY-MASS SPECTROMETRY; NATIVE MASS SPECTROMETRIES; NON-LINEAR RESPONSE;

IONS;

ION;

ARTICLE; DIFFUSION; ELECTRIC FIELD; ION MOBILITY SPECTROMETRY; OPTICAL RESOLUTION; RADIOFREQUENCY; TEMPERATURE; TIME;

EID: 84994050569     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-016-1479-9     Document Type: Article

References (57)

1. May, J.C., McLean, J.A.: Ion mobility-mass spectrometry: time-dispersive instrumentation. Anal. Chem. 87, 1422–1436 (2015)
2. Uetrecht, C., Barbu, I.M., Shoemaker, G.K., van Duijn, E., Heck, A.J.R.: Interrogating viral capsid assembly with ion mobility–mass spectrometry. Nat. Chem. 3, 126–132 (2011)
3. Rabuck, J.N., Hyung, S.-J., Ko, K.S., Fox, C.C., Soellner, M.B., Ruotolo, B.T.: Activation state-selective kinase inhibitor assay based on ion mobility-mass spectrometry. Anal. Chem. 85, 6995–7002 (2013)
4. Zhou, M., Jones, C.M., Wysocki, V.H.: Dissecting the large noncovalent protein complex groel with surface-induced dissociation and ion mobility-mass spectrometry. Anal. Chem. 85, 8262–8267 (2013)
5. Zhou, M., Politis, A., Davies, R.B., Liko, I., Wu, K.-J., Stewart, A.G., Stock, D., Robinson, C.V.: Ion mobility-mass spectrometry of a rotary ATPase reveals ATP-induced reduction in conformational flexibility. Nat. Chem. 6, 208–215 (2014)
6. D’Agostino, P.A., Chenier, C.L.: Desorption electrospray ionization mass spectrometric analysis of organophosphorus chemical warfare agents using ion mobility and tandem mass spectrometry. Rapid Commun. Mass Spectrom. 24, 1617–1624 (2010)
7. Reynolds, J.C., Blackburn, G.J., Guallar-Hoyas, C., Moll, V.H., Bocos-Bintintan, V., Kaur-Atwal, G., Howdle, M.D., Harry, E.L., Brown, L.J., Creaser, C.S., Thomas, C.L.P.: Detection of volatile organic compounds in breath using thermal desorption electrospray ionization-ion mobility-mass spectrometry. Anal. Chem. 82, 2139–2144 (2010)
8. Campuzano, I., Bush, M.F., Robinson, C.V., Beaumont, C., Richardson, K., Kim, H., Kim, H.I.: Structural characterization of drug-like compounds by ion mobility mass spectrometry: comparison of theoretical and experimentally derived nitrogen collision cross sections. Anal. Chem. 84, 1026–1033 (2012)
9. Bush, M.F., Hall, Z., Giles, K., Hoyes, J., Robinson, C.V., Ruotolo, B.T.: Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology. Anal. Chem. 82, 9557–9565 (2010)
10. Lietz, C.B., Yu, Q., Li, L.: Large-scale collision cross-section profiling on a traveling wave ion mobility mass spectrometer. J. Am. Soc. Mass Spectrom. 25, 2009–2019 (2014)
11. Hofmann, J., Hahm, H.S., Seeberger, P.H., Pagel, K.: Identification of carbohydrate anomers using ion mobility-mass spectrometry. Nature 526, 241–244 (2015)
12. Groessl, M., Graf, S., Knochenmuss, R.: High resolution ion mobility-mass spectrometry for separation and identification of isomeric lipids. Analyst 140, 6904–6911 (2015)
13. Jurneczko, E., Cruickshank, F., Porrini, M., Nikolova, P., Campuzano, I.D.G., Morris, M., Barran, P.E.: Intrinsic disorder in proteins: a challenge for (un)structural biology met by ion mobility-mass spectrometry. Biochem. Soc. Trans. 40, 1021–1026 (2012)
14. Ruotolo, B.T., Giles, K., Campuzano, I., Sandercock, A.M., Bateman, R.H., Robinson, C.V.: Evidence for macromolecular protein rings in the absence of bulk water. Science 310, 1658–1661 (2005)
15. Giles, K., Williams, J.P., Campuzano, I.: Enhancements in travelling wave ion mobility resolution. Rapid Commun. Mass Spectrom. 25, 1559–1566 (2011)
16. Silveira, J.A., Ridgeway, M.E., Park, M.A.: High resolution trapped ion mobility spectrometery of peptides. Anal. Chem. 86, 5624–5627 (2014)
17. Shelimov, K.B., Clemmer, D.E., Hudgins, R.R., Jarrold, M.F.: Protein structure in vacuo: gas-phase conformations of BPTI and cytochrome c. J. Am. Chem. Soc. 119, 2240–2248 (1997)
18. Kemper, P.R., Dupuis, N.F., Bowers, M.T.: A new, higher resolution, ion mobility mass spectrometer. Int. J. Mass Spectrom. 287, 46–57 (2009)
19. May, J.C., Goodwin, C.R., Lareau, N.M., Leaptrot, K.L., Morris, C.B., Kurulugama, R.T., Mordehai, A., Klein, C., Barry, W., Darland, E., Overney, G., Imatani, K., Stafford, G.C., Fjeldsted, J.C., McLean, J.A.: Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer. Anal. Chem. 86, 2107–2116 (2014)
20. Dugourd, P., Hudgins, R.R., Clemmer, D.E., Jarrold, M.F.: High-resolution ion mobility measurements. Rev. Sci. Instrum. 68, 1122–1129 (1997)
21. Baker, E.S., Clowers, B.H., Li, F., Tang, K., Tolmachev, A.V., Prior, D.C., Belov, M.E., Smith, R.D.: Ion mobility spectrometry—mass spectrometry performance using electrodynamic ion funnels and elevated drift gas pressures. J. Am. Soc. Mass Spectrom. 18, 1176–1187 (2007)
22. Ibrahim, Y.M., Baker, E.S., Danielson III, W.F., Norheim, R.V., Prior, D.C., Anderson, G.A., Belov, M.E., Smith, R.D.: Development of a new ion mobility time-of-flight mass spectrometer. Int. J. Mass Spectrom. 377, 655–662 (2015)
23. Mason, E.A., McDaniel, E.W.: Transport properties of ions in gases, p. 276. Wiley, New York (1988)
24. Revercomb, H.E., Mason, E.A.: Theory of plasma chromatography/gaseous electrophoresis - a review. Anal. Chem. 47, 970–983 (1975)
25. Tang, K., Shvartsburg, A.A., Lee, H.-N., Prior, D.C., Buschbach, M.A., Li, F., Tolmachev, A.V., Anderson, G.A., Smith, R.D.: High-sensitivity ion mobility spectrometry/mass spectrometry using electrodynamic ion funnel interfaces. Anal. Chem. 77, 3330–3339 (2005)
26. Guevremont, R., Siu, K.W.M., Wang, J., Ding, L.: Combined ion mobility/time-of-flight mass spectrometry study of electrospray-generated ions. Anal. Chem. 69, 3959–3965 (1997)
27. Gillig, K.J., Ruotolo, B., Stone, E.G., Russell, D.H., Fuhrer, K., Gonin, M., Schultz, A.J.: Coupling high-pressure MALDI with ion mobility/orthogonal time-of-flight mass spectrometry. Anal. Chem. 72, 3965–3971 (2000)
28. Gerlich, D.: In state selected and state-to state ion–molecule reaction dynamics. part 1. experiment. Wiley, New York (1992)
29. Kim, T., Tolmachev, A.V., Harkewicz, R., Prior, D.C., Anderson, G., Udseth, H.R., Smith, R.D., Bailey, T.H., Rakov, S., Futrell, J.H.: Design and implementation of a new electrodynamic ion funnel. Anal. Chem. 72, 2247–2255 (2000)
30. Lynn, E.C., Chung, M.C., Han, C.C.: Characterizing the transmission properties of an ion funnel. Rapid Commun. Mass Spectrom. 14, 2129–2134 (2000)
31. Javahery, G., Thomson, B.: A segmented radiofrequency-only quadrupole collision cell for measurements of ion collision cross section on a triple quadrupole mass spectrometer. J. Am. Soc. Mass Spectrom. 8, 697–702 (1997)
32. McCullough, B.J., Kalapothakis, J., Eastwood, H., Kemper, P., MacMillan, D., Taylor, K., Dorin, J., Barran, P.E.: Development of an Ion mobility quadrupole time of flight mass spectrometer. Anal. Chem. 80, 6336–6344 (2008)
33. Covey, T., Douglas, D.J.: Collision cross-sections for protein ions. J. Am. Soc. Mass Spectrom. 4, 616–623 (1993)
34. Gill, A.C., Jennings, K.R., Wyttenbach, T., Bowers, M.T.: Conformations of biopolymers in the gas phase: a new mass spectrometric method. Int. J. Mass Spectrom. 195/196, 685–697 (2000)
35. Thalassinos, K., Slade, S.E., Jennings, K.R., Scrivens, J.H., Giles, K., Wildgoose, J., Hoyes, J., Bateman, R.H., Bowers, M.T.: Ion mobility mass spectrometry of proteins in a modified commercial mass spectrometer. Int. J. Mass Spectrom. 236, 55–63 (2004)
36. Zucker, S.M., Ewing, M.A., Clemmer, D.E.: Gridless overtone mobility spectrometry. Anal. Chem. 85, 10174–10179 (2013)
37. Tolmachev, A.V., Webb, I.K., Ibrahim, Y.M., Garimella, S.V.B., Zhang, X., Anderson, G.A., Smith, R.D.: Characterization of ion dynamics in structures for lossless ion manipulations. Anal. Chem. 86, 9162–9168 (2014)
38. Allen, S.J., Giles, K., Gilbert, T., Bush, M.F.: Ion mobility mass spectrometry of peptide, protein, and protein complex ions using a radio frequency-confining drift cell. Analyst 141, 884–891 (2016)
39. Allen, S.J., Schwartz, A.M., Bush, M.F.: Effects of polarity on the structures and charge states of native-like proteins and protein complexes in the gas phase. Anal. Chem. 85, 12055–12061 (2013)
40. Silveira, J.A., Jeon, J., Gamage, C.M., Pai, P.-J., Fort, K.L., Russell, D.H.: Damping factor links periodic focusing and uniform field ion mobility for accurate determination of collision cross sections. Anal. Chem. 84, 2818–2824 (2012)
41. Silveira, J.A., Gamage, C.M., Blase, R.C., Russell, D.H.: Gas-phase ion dynamics in a periodic-focusing DC ion guide. Int. J. Mass Spectrom. 296, 36–42 (2010)
42. Blase, R.C., Silveira, J.A., Gillig, K.J., Gamage, C.M., Russell, D.H.: Increased ion transmission in IMS: a high resolution, periodic-focusing DC ion guide ion mobility spectrometer. Int. J. Mass Spectrom. 301, 166–173 (2011)
43. Gamage, C.M., Silveira, J.A., Blase, R.C., Russell, D.H.: Gas-phase ion dynamics in a periodic-focusing DC ion guide (Part II): Discrete transport modes. Int. J. Mass Spectrom. 303, 154–163 (2011)
44. Freeke, J., Bush, M.F., Robinson, C.V., Ruotolo, B.T.: Gas-phase protein assemblies: unfolding landscapes and preserving native-like structures using noncovalent adducts. Chem. Phys. Lett. 524, 1–9 (2012)
45. Hall, Z., Politis, A., Bush, M.F., Smith, L.J., Robinson, C.V.: Charge-state dependent compaction and dissociation of protein complexes: insights from ion mobility and molecular dynamics. J. Am. Chem. Soc. 134, 3429–3438 (2012)
46. Mason, E.A., McDaniel, E.W.: In: Transport properties of ions in gases, p. 149. Wiley, New York (1988)
47. Mason, E.A., McDaniel, E.W.: Transport properties of ions in gases, p. 154. Wiley, New York (1988)
48. Mason, E.A., McDaniel, E.W.: Transport properties of ions in gases, p. 4. Wiley, New York (1988)
49. Shvartsburg, A.A., Smith, R.D.: Fundamentals of traveling wave ion mobility spectrometry. Anal. Chem. 80, 9689–9699 (2008)
50. Morsa, D., Gabelica, V., De Pauw, E.: Effective temperature of ions in traveling wave ion mobility spectrometry. Anal. Chem. 83, 5775–5782 (2011)
51. Merenbloom, S.I., Flick, T.G., Williams, E.R.: How hot are your ions in TWAVE ion mobility spectrometry? J. Am. Soc. Mass Spectrom. 23, 553–562 (2011)
52. Dahl, D.: SIMION. version 8.0; Idaho National Engineering Laboratory: Idaho Falls, ID
53. Tolmachev, A.V., Kim, T., Udseth, H.R., Smith, R.D., Bailey, T.H., Futrell, J.H.: Simulation-based optimization of the electrodynamic ion funnel for high sensitivity electrospray ionization mass spectrometry. Int. J. Mass Spectrom. 203, 31–47 (2000)
54. Shaffer, S.A., Tolmachev, A., Prior, D.C., Anderson, G.A., Udseth, H.R., Smith, R.D.: Characterization of an improved electrodynamic ion funnel interface for electrospray ionization mass spectrometry. Anal. Chem. 71, 2957–2964 (1999)
55. Tolmachev, A.V., Chernushevich, I.V., Dodonov, A.F., Standing, K.G.: A collisional focusing ion guide for coupling an atmospheric pressure ion source to a mass spectrometer. Nucl. Instrum. Methods Phys. Res. B 124, 112–119 (1997)
56. Schnier, P.D., Price, W.D., Jockusch, R.A., Williams, E.R.: Blackbody infrared radiative dissociation of bradykinin and its analogues: energetics, dynamics, and evidence for salt-bridge structures in the gas phase. J. Am. Chem. Soc. 118, 7178–7189 (1996)
57. Marquardt, D.W.: An algorithm for least-squares estimation of nonlinear parameters. J. Appl. Math. 11, 431–441 (1963)