A single mutation at position 190 in hemagglutinin enhances binding affinity for human type sialic acid receptor and replication of H9N2 avian influenza virus in mice

Journal of Virology

Volumn 90, Issue 21, 2016, Pages 9806-9825

  Teng, Qiaoyang ^a   Xu, Dawei ^a   Shen, Weixia ^a   Liu, Qinfang ^a   Rong, Guangyu ^a   Li, Xuesong ^a   Yan, Liping ^a   Yang, Jianmei ^a,b   Chen, Hongjun ^a   Yu, Hai ^a   Ma, Wenjun ^b   Li, Zejun ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b KANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMAGGLUTININ RECEPTOR; INFLUENZA VIRUS HEMAGGLUTININ; LEUCINE; RECEPTOR; SIALIC ACID RECEPTOR; UNCLASSIFIED DRUG; VALINE; VIRUS RECEPTOR; CELL SURFACE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CHINA; CONTROLLED STUDY; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLUENZA A VIRUS (H9N2); MOUSE; MUTATION; MUTATIONAL ANALYSIS; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; RECEPTOR BINDING; VIRUS ATTACHMENT; VIRUS REPLICATION; A-549 CELL LINE; ANIMAL; AVIAN INFLUENZA; BAGG ALBINO MOUSE; BIRD; DNA REPLICATION; GENETICS; INFLUENZA; LUNG; METABOLISM; ORTHOMYXOVIRUS INFECTION; TUMOR CELL LINE; VIROLOGY;

A549 CELLS; ANIMALS; BIRDS; CELL LINE, TUMOR; DNA REPLICATION; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H9N2 SUBTYPE; INFLUENZA IN BIRDS; INFLUENZA, HUMAN; LUNG; MICE; MICE, INBRED BALB C; MUTATION; ORTHOMYXOVIRIDAE INFECTIONS; PHYLOGENY; RECEPTORS, CELL SURFACE; VIRUS ATTACHMENT; VIRUS REPLICATION;

EID: 84993946916     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01141-16     Document Type: Article

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