Mitochondrial DNA damage associated molecular patterns in ventilator-associated pneumonia: Prevention and reversal by intratracheal DNase i

Journal of Trauma and Acute Care Surgery

Volumn 82, Issue 1, 2017, Pages 120-125

  Simmons, Jon D ^a   Freno, Daniel R ^a   Muscat, C Annie ^a   Obiako, Boniface ^a   Lee, Yann Leei L ^a   Pastukh, Viktor M ^a   Brevard, Sidney B ^a   Gillespie, Mark N ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

DAMPs; DNase; Dornase ; Mitochondrial DNA; Ventilator associated pneumonia

Indexed keywords

BACTERIAL DNA; CELL NUCLEUS DNA; DEOXYRIBONUCLEASE I; MITOCHONDRIAL DNA; RNA 16S;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BACTERIAL PNEUMONIA; BACTERIAL STRAIN; CLINICAL ARTICLE; CONFERENCE PAPER; DNA DAMAGE; DNA DEGRADATION; DNA ISOLATION; ENDOTHELIAL DYSFUNCTION; HUMAN; HYPOTHESIS; ISOLATED LUNG; LUNG LAVAGE; LUNG PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PSEUDOMONAS AERUGINOSA; RAT; VENTILATOR ASSOCIATED PNEUMONIA; ALABAMA; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; METABOLISM; MICROBIOLOGY; PNEUMONIA, BACTERIAL; PNEUMONIA, VENTILATOR-ASSOCIATED; REAL TIME POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ALABAMA; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; DEOXYRIBONUCLEASE I; DNA DAMAGE; DNA, MITOCHONDRIAL; HUMANS; MALE; PNEUMONIA, BACTERIAL; PNEUMONIA, VENTILATOR-ASSOCIATED; PROSPECTIVE STUDIES; PSEUDOMONAS AERUGINOSA; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84992679715     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0000000000001269     Document Type: Conference Paper

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