The anti-cancerous drug doxorubicin decreases the c-di-GMP content in Pseudomonas aeruginosa but promotes biofilm formation

Microbiology (United Kingdom)

Volumn 162, Issue 10, 2016, Pages 1797-1807

  Groizeleau, Julie ^a   Rybtke, Morten ^a   Andersen, Jens Bo ^a   Berthelsen, Jens ^a   Liu, Yang ^b   Yang, Liang ^b   Nielsen, Thomas E ^a   Kaever, Volkhard ^c   Givskov, Michael ^a,b   Tolker Nielsen, Tim ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Biofilm dispersal; Biofilm inhibition; c di GMP; Doxorubicin; Pseudomonas aeruginosa

Indexed keywords

BACTERIAL DNA; BACTERIAL PROTEIN; CYCLIC GMP; DOXORUBICIN; PROTEIN WSPR; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BIS(3',5')-CYCLIC DIGUANYLIC ACID;

ARTICLE; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; BIOFILM; CONTROLLED STUDY; NONHUMAN; PLASMID; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SCREENING; ANALOGS AND DERIVATIVES; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY;

ANTINEOPLASTIC AGENTS; BACTERIAL PROTEINS; BIOFILMS; CYCLIC GMP; DOXORUBICIN; GENE EXPRESSION REGULATION, BACTERIAL; PSEUDOMONAS AERUGINOSA;

EID: 84992679375     PISSN: 13500872     EISSN: 14652080     Source Type: Journal    
DOI: 10.1099/mic.0.000354     Document Type: Article

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