Does upregulated host cell receptor expression provide a link between bacterial adhesion and chronic respiratory disease?

Journal of Translational Medicine

Volumn 14, Issue 1, 2016, Pages

  O'Toole, Ronan F ^a   Shukla, Shakti D ^a   Walters, Eugene H ^a  

^a UNIVERSITY OF TASMANIA   (Australia)

Author keywords

Airway epithelium; Non typeable Haemophilus influenzae; Platelet activating factor receptor; Streptococcus pneumoniae

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; FIBRINOGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR;

BACTERIUM ADHERENCE; BRONCHUS MUCOSA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CHRONIC RESPIRATORY TRACT DISEASE; DISEASE ASSOCIATION; HAEMOPHILUS INFLUENZAE; HUMAN; NONHUMAN; NOTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; STREPTOCOCCUS PNEUMONIAE; UPREGULATION; ANIMAL; HOST PATHOGEN INTERACTION; METABOLISM; MICROBIOLOGY; PHYSIOLOGY;

ANIMALS; BACTERIAL ADHESION; HAEMOPHILUS INFLUENZAE; HOST-PATHOGEN INTERACTIONS; HUMANS; PLATELET MEMBRANE GLYCOPROTEINS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, G-PROTEIN-COUPLED; STREPTOCOCCUS PNEUMONIAE; UP-REGULATION;

EID: 84992365971     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-016-1063-x     Document Type: Note

References (30)

1. World Health Organization. The top 10 causes of death, in Fact Sheet No. 310. Geneva: WHO; 2014.
2. Sethi S, Murphy TF. Infection in the pathogenesis and course of chronic obstructive pulmonary disease. N Engl J Med. 2008;359:2355-65.
3. Beasley V, Joshi PV, Singanayagam A, Molyneaux PL, Johnston SL, Mallia P. Lung microbiology and exacerbations in COPD. Int J Chron Obstruct Pulmon Dis. 2012;7:555-69.
4. Lokke A, Lange P, Scharling H, Fabricius P, Vestbo J. Developing COPD: a 25year follow up study of the general population. Thorax. 2006;61:935-9.
5. Taylor JD. COPD and the response of the lung to tobacco smoke exposure. Pulm Pharmacol Ther. 2010;23:376-83.
6. Shukla SD, Sohal SS, Mahmood MQ, Reid D, Muller HK, Walters EH. Airway epithelial platelet-activating factor receptor expression is markedly upregulated in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2014;9:853-61.
7. Shukla SD, Muller HK, Latham R, Sohal SS, Walters EH. Platelet-activating factor receptor (PAFr) is upregulated in small airways and alveoli of smokers and COPD patients. Respirology. 2016
8. Shukla SD, Fairbairn RL, Gell DA, Latham RD, Sohal SS, Walters EH, O'Toole RF. An antagonist of the platelet-activating factor receptor inhibits adherence of both non-typeable Haemophilus influenzae and Streptococcus pneumoniae to cultured human bronchial epithelial cells exposed to cigarette smoke. Int J Chronic Obstruct Pulm Dis. 2016;11:1647-55.
9. Shukla SD, Sohal SS, O'Toole RF, Eapen MS, Walters EH. Platelet activating factor receptor: gateway for bacterial chronic airway infection in chronic obstructive pulmonary disease and potential therapeutic target. Expert Rev Respir Med. 2015;9:473-85.
10. Ishii S, Nagase T, Shimizu T. Platelet-activating factor receptor. Prostaglandins other lipid mediat. 2002;68-69:599-609.
11. Le Texier L, Favre E, Redeuilh C, Blavet N, Bellahsene T, Dive G, Pirotzky E, Godfroid JJ. Structure-activity relationships in platelet-activating factor (PAF). 7. Tetrahydrofuran derivatives as dual PAF antagonists and acetylcholinesterase inhibitors. Synthesis and PAF-antagonistic activity. J Lipid Mediat Cell Signal. 1996;13:189-205.
12. Saeed SA, Simjee RU, Mahmood F, Rahman NN. Dual inhibition of platelet-activating factor and arachidonic acid metabolism by ajmaline and effect on carrageenan-induced rat paw oedema. J Pharm Pharmacol. 1993;45:715-9.
13. Morigi M, Macconi D, Riccardi E, Boccardo P, Zilio P, Bertani T, Remuzzi G. Platelet-activating factor receptor blocking reduces proteinuria and improves survival in lupus autoimmune mice. J Pharmacol Exp Ther. 1991;258:601-6.
14. Gomez FP, Roca J, Barbera JA, Chung KF, Peinado VI, Rodriguez-Roisin R. Effect of a platelet-activating factor (PAF) antagonist, SR 27417A, on PAF-induced gas exchange abnormalities in mild asthma. Eur Respir J. 1998;11:835-9.
15. Arnout J, van Hecken A, De Lepeleire I, Miyamoto Y, Holmes I, De Schepper P, Vermylen J. Effectiveness and tolerability of CV-3988, a selective PAF antagonist, after intravenous administration to man. Br J Clin Pharmacol. 1988;25:445-51.
16. Hsieh KH. Effects of PAF antagonist, BN52021, on the PAF-, methacholine-, and allergen-induced bronchoconstriction in asthmatic children. Chest. 1991;99:877-82.
17. Barbier M, Oliver A, Rao J, Hanna SL, Goldberg JB, Albertí S. Novel Phosphorylcholine-containing protein of Pseudomonas aeruginosa chronic infection isolates interacts with airway epithelial cells. J Infect Dis. 2008;197:465-73.
18. Mallet de Lima CD, da Conceicao Costa J, de Oliveira Lima Santos SA, Carvalho S, de Carvalho L, Albano RM, Teixeira MM, Plotkowski MC, Saliba AM. Central role of PAFR signalling in ExoU-induced NF-kappaB activation. Cell Microbiol. 2014;16:1244-54.
19. Avadhanula V, Rodriguez CA, Ulett GC, Bakaletz LO, Adderson EE. Nontypeable Haemophilus influenzae adheres to intercellular adhesion molecule 1 (ICAM-1) on respiratory epithelial cells and upregulates ICAM-1 expression. Infect Immun. 2006;74:830-8.
20. Frick AG, Joseph TD, Pang L, Rabe AM, St Geme JW, Look DC. Haemophilus influenzae stimulates ICAM-1 expression on respiratory epithelial cells. J Immunol. 2000;164:4185-96.
21. Barnich N, Carvalho FA, Glasser AL, Darcha C, Jantscheff P, Allez M, Peeters H, Bommelaer G, Desreumaux P, Colombel JF, Darfeuille-Michaud A. CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. J Clin Invest. 2007;117:1566-74.
22. Li N, Ren A, Wang X, Fan X, Zhao Y, Gao GF, Cleary P, Wang B. Influenza viral neuraminidase primes bacterial coinfection through TGF-beta-mediated expression of host cell receptors. Proc Natl Acad Sci USA. 2015;112:238-43.
23. Avadhanula V, Rodriguez CA, DeVincenzo JP, Wang Y, Webby RJ, Ulett GC, Adderson EE. Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner. J Virol. 2006;80:1629-36.
24. Avadhanula V, Wang Y, Portner A, Adderson E. Nontypeable Haemophilus influenzae and Streptococcus pneumoniae bind respiratory syncytial virus glycoprotein. J Med Microbiol. 2007;56:1133-7.
25. Wang JH, Kwon HJ, Jang YJ. Rhinovirus Enhances Various Bacterial Adhesions to Nasal Epithelial Cells Simultaneously. Laryngoscope. 2009;119:1406-11.
26. Ishizuka S, Yamaya M, Suzuki T, Takahashi H, Ida S, Sasaki T, Inoue D, Sekizawa K, Nishimura H, Sasaki H. Effects of rhinovirus infection on the adherence of Streptococcus pneumoniae to cultured human airway epithelial cells. J Infect Dis. 2003;188:1928-39.
27. Papi A, Bellettato CM, Braccioni F, Romagnoli M, Casolari P, Caramori G, Fabbri LM, Johnston SL. Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations. Am J Respir Crit Care Med. 2006;173:1114-21.
28. Cellai C, Laurenzana A, Vannucchi AM, Caporale R, Paglierani M, Di Lollo S, Pancrazzi A, Paoletti F. Growth inhibition and differentiation of human breast cancer cells by the PAFR antagonist WEB-2086. Br J Cancer. 2006;94:1637-42.
29. Cellai C, Laurenzana A, Vannucchi AM, Della Malva N, Bianchi L, Paoletti F. Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells. FASEB J. 2002;16:733-5.
30. Kato M, Imoto K, Miyake H, Oda T, Miyaji S, Nakamura M. Apafant, a potent platelet-activating factor antagonist, blocks eosinophil activation and is effective in the chronic phase of experimental allergic conjunctivitis in guinea pigs. J Pharmacol Sci. 2004;95:435-42.