메뉴 건너뛰기




Volumn 14, Issue 5, 2016, Pages 4445-4453

Rab5a-mediated autophagy regulates the phenotype and behavior of vascular smooth muscle cells

Author keywords

Autophagy; ERK1 2 signaling pathway; Phenotype transition; Rab5a; Vascular smooth muscle cells

Indexed keywords

PLATELET DERIVED GROWTH FACTOR; RAB PROTEIN; SMALL INTERFERING RNA; SULFORHODAMINE B; RAB5C PROTEIN, HUMAN;

EID: 84992317676     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2016.5774     Document Type: Article
Times cited : (12)

References (36)
  • 1
    • 3042588831 scopus 로고    scopus 로고
    • Molecular regulation of vascular smooth muscle cell differentiation in development and disease
    • Owens GK, Kumar MS and Wamhoff BR: Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 84: 767-801, 2004.
    • (2004) Physiol Rev , vol.84 , pp. 767-801
    • Owens, G.K.1    Kumar, M.S.2    Wamhoff, B.R.3
  • 2
    • 77954587784 scopus 로고    scopus 로고
    • Atheromas feel the pressure: Biomechanical stress and atherosclerosis
    • Pyle AL and Young PP: Atheromas feel the pressure: Biomechanical stress and atherosclerosis. Am J Pathol 177: 4-9, 2010.
    • (2010) Am J Pathol , vol.177 , pp. 4-9
    • Pyle, A.L.1    Young, P.P.2
  • 3
    • 38449095878 scopus 로고    scopus 로고
    • The role of vascular smooth muscle cells on the pathogenesis of atherosclerosis
    • Rudijanto A: The role of vascular smooth muscle cells on the pathogenesis of atherosclerosis. Acta Med Indones 39: 86-93, 2007.
    • (2007) Acta Med Indones , vol.39 , pp. 86-93
    • Rudijanto, A.1
  • 4
    • 79959725180 scopus 로고    scopus 로고
    • Signaling mechanisms that regulate smooth muscle cell differentiation
    • Mack CP: Signaling mechanisms that regulate smooth muscle cell differentiation. Arterioscler Thromb Vasc Biol 31: 1495-1505, 2011.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1495-1505
    • Mack, C.P.1
  • 5
    • 27744520682 scopus 로고    scopus 로고
    • Rab proteins, connecting transport and vesicle fusion
    • Jordens I, Marsman M, Kuijl C and Neefjes J: Rab proteins, connecting transport and vesicle fusion. Traffic 6: 1070-1077, 2005.
    • (2005) Traffic , vol.6 , pp. 1070-1077
    • Jordens, I.1    Marsman, M.2    Kuijl, C.3    Neefjes, J.4
  • 6
    • 33747066132 scopus 로고    scopus 로고
    • Rabs and their effectors: Achieving specificity in membrane traffic
    • Grosshans BL, Ortiz D and Novick P: Rabs and their effectors: Achieving specificity in membrane traffic. Proc Natl Acad Sci USA 103: 11821-11827, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11821-11827
    • Grosshans, B.L.1    Ortiz, D.2    Novick, P.3
  • 7
    • 78751656754 scopus 로고    scopus 로고
    • Role of Rab GTPases in membrane traffic and cell physiology
    • Hutagalung AH and Novick PJ: Role of Rab GTPases in membrane traffic and cell physiology. Physiol Rev 91: 119-149, 2011.
    • (2011) Physiol Rev , vol.91 , pp. 119-149
    • Hutagalung, A.H.1    Novick, P.J.2
  • 8
    • 46249127490 scopus 로고    scopus 로고
    • Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease
    • Ravikumar B, Imarisio S, Sarkar S, O'Kane CJ and Rubinsztein DC: Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease. J Cell Sci 121: 1649-1660, 2008.
    • (2008) J Cell Sci , vol.121 , pp. 1649-1660
    • Ravikumar, B.1    Imarisio, S.2    Sarkar, S.3    O'Kane, C.J.4    Rubinsztein, D.C.5
  • 10
    • 80051645654 scopus 로고    scopus 로고
    • Knockdown of Rab5a expression decreases cancer cell motility and invasion through integrin-mediated signaling pathway
    • Liu SS, Chen XM, Zheng HX, Shi SL and Li Y: Knockdown of Rab5a expression decreases cancer cell motility and invasion through integrin-mediated signaling pathway. J Biomed Sci 18: 58, 2011.
    • (2011) J Biomed Sci , vol.18 , pp. 58
    • Liu, S.S.1    Chen, X.M.2    Zheng, H.X.3    Shi, S.L.4    Li, Y.5
  • 11
    • 77954169426 scopus 로고    scopus 로고
    • Rab5a overexpression promoting ovarian cancer cell proliferation may be associated with APPL1-related epidermal growth factor signaling pathway
    • Zhao Z, Liu XF, Wu HC, Zou SB, Wang JY, Ni PH, Chen XH and Fan QS: Rab5a overexpression promoting ovarian cancer cell proliferation may be associated with APPL1-related epidermal growth factor signaling pathway. Cancer Sci 101: 1454-1462, 2010.
    • (2010) Cancer Sci , vol.101 , pp. 1454-1462
    • Zhao, Z.1    Liu, X.F.2    Wu, H.C.3    Zou, S.B.4    Wang, J.Y.5    Ni, P.H.6    Chen, X.H.7    Fan, Q.S.8
  • 12
    • 34548649469 scopus 로고    scopus 로고
    • Expression of Rab5a in hepatocellular carcinoma: Possible involvement in epidermal growth factor signaling
    • Fukui K, Tamura S, Wada A, Kamada Y, Igura T, Kiso S and Hayashi N: Expression of Rab5a in hepatocellular carcinoma: Possible involvement in epidermal growth factor signaling. Hepatol Res 37: 957-965, 2007.
    • (2007) Hepatol Res , vol.37 , pp. 957-965
    • Fukui, K.1    Tamura, S.2    Wada, A.3    Kamada, Y.4    Igura, T.5    Kiso, S.6    Hayashi, N.7
  • 13
    • 78149375890 scopus 로고    scopus 로고
    • RNAi-mediated Rab5a suppression inhibits proliferation and migration of vascular smooth muscle cells
    • Ma Z, Wang H, Wu L, Zhui L, Shi W, Ma D, Chen Z and Yu B: RNAi-mediated Rab5a suppression inhibits proliferation and migration of vascular smooth muscle cells. Acta Cardiol 65: 507-514, 2010.
    • (2010) Acta Cardiol , vol.65 , pp. 507-514
    • Ma, Z.1    Wang, H.2    Wu, L.3    Zhui, L.4    Shi, W.5    Ma, D.6    Chen, Z.7    Yu, B.8
  • 14
    • 84876237304 scopus 로고    scopus 로고
    • PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress
    • Salabei JK, Cummins TD, Singh M, Jones SP, Bhatnagar A and Hill BG: PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress. Biochem J 451: 375-388, 2013.
    • (2013) Biochem J , vol.451 , pp. 375-388
    • Salabei, J.K.1    Cummins, T.D.2    Singh, M.3    Jones, S.P.4    Bhatnagar, A.5    Hill, B.G.6
  • 15
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2CT method
    • Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2CT method. Methods 25: 402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 16
    • 84908160993 scopus 로고    scopus 로고
    • Molecular and functional interactions among monocytes/macrophages and smooth muscle cells and their relevance for atherosclerosis
    • Butoi E, Gan AM and Manduteanu I: Molecular and functional interactions among monocytes/macrophages and smooth muscle cells and their relevance for atherosclerosis. Crit Rev Eukaryot Gene Expr 24: 341-355, 2014.
    • (2014) Crit Rev Eukaryot Gene Expr , vol.24 , pp. 341-355
    • Butoi, E.1    Gan, A.M.2    Manduteanu, I.3
  • 17
    • 0034698057 scopus 로고    scopus 로고
    • Induction of smooth muscle alpha-actin in vascular smooth muscle cells by arginine vasopressin is mediated by c-Jun amino-terminal kinases and p38 mitogen-activated protein kinase
    • Garat C, Van Putten V, Refaat ZA, Dessev C, Han SY and Nemenoff RA: Induction of smooth muscle alpha-actin in vascular smooth muscle cells by arginine vasopressin is mediated by c-Jun amino-terminal kinases and p38 mitogen-activated protein kinase. J Biol Chem 275: 22537-22543, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 22537-22543
    • Garat, C.1    Van Putten, V.2    Refaat, Z.A.3    Dessev, C.4    Han, S.Y.5    Nemenoff, R.A.6
  • 18
    • 0030862962 scopus 로고    scopus 로고
    • Angiotensin II-induced stimulation of smooth muscle alpha-actin expression by serum response factor and the homeodomain transcription factor MHox
    • Hautmann MB, Thompson MM, Swartz EA, Olson EN and Owens GK: Angiotensin II-induced stimulation of smooth muscle alpha-actin expression by serum response factor and the homeodomain transcription factor MHox. Circ Res 81: 600-610, 1997.
    • (1997) Circ Res , vol.81 , pp. 600-610
    • Hautmann, M.B.1    Thompson, M.M.2    Swartz, E.A.3    Olson, E.N.4    Owens, G.K.5
  • 19
    • 77649099042 scopus 로고    scopus 로고
    • Cartilage oligomeric matrix protein maintains the contractile phenotype of vascular smooth muscle cells by interacting with alpha(7)beta(1) integrin
    • Wang L, Zheng J, Du Y, Huang Y, Li J, Liu B, Liu CJ, Zhu Y, Gao Y, Xu Q, et al: Cartilage oligomeric matrix protein maintains the contractile phenotype of vascular smooth muscle cells by interacting with alpha(7)beta(1) integrin. Circ Res 106: 514-525, 2010.
    • (2010) Circ Res , vol.106 , pp. 514-525
    • Wang, L.1    Zheng, J.2    Du, Y.3    Huang, Y.4    Li, J.5    Liu, B.6    Liu, C.J.7    Zhu, Y.8    Gao, Y.9    Xu, Q.10
  • 20
    • 80054978956 scopus 로고    scopus 로고
    • Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy
    • Su WC, Chao TC, Huang YL, Weng SC, Jeng KS and Lai MM: Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy. J Virol 85: 10561-10571, 2011.
    • (2011) J Virol , vol.85 , pp. 10561-10571
    • Su, W.C.1    Chao, T.C.2    Huang, Y.L.3    Weng, S.C.4    Jeng, K.S.5    Lai, M.M.6
  • 21
    • 0344353645 scopus 로고    scopus 로고
    • Inhibition of platelet-derived growth factor receptor tyrosine kinase inhibits vascular smooth muscle cell migration and proliferation
    • Myllärniemi M, Calderon L, Lemström K, Buchdunger E and Häyry P: Inhibition of platelet-derived growth factor receptor tyrosine kinase inhibits vascular smooth muscle cell migration and proliferation. FASEB J 11: 1119-1126, 1997.
    • (1997) FASEB J , vol.11 , pp. 1119-1126
    • Myllärniemi, M.1    Calderon, L.2    Lemström, K.3    Buchdunger, E.4    Häyry, P.5
  • 22
    • 0034888832 scopus 로고    scopus 로고
    • Efficacy of the novel selective platelet-derived growth factor receptor antagonist CT52923 on cellular proliferation, migration, and suppression of neointima following vascular injury
    • Yu JC, Lokker NA, Hollenbach S, Apatira M, Li J, Betz A, Sedlock D, Oda S, Nomoto Y, Matsuno K, et al: Efficacy of the novel selective platelet-derived growth factor receptor antagonist CT52923 on cellular proliferation, migration, and suppression of neointima following vascular injury. J Pharmacol Exp Ther 298: 1172-1178, 2001.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 1172-1178
    • Yu, J.C.1    Lokker, N.A.2    Hollenbach, S.3    Apatira, M.4    Li, J.5    Betz, A.6    Sedlock, D.7    Oda, S.8    Nomoto, Y.9    Matsuno, K.10
  • 23
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • Levine B and Klionsky DJ: Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Dev Cell 6: 463-477, 2004.
    • (2004) Dev Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 25
    • 63849220367 scopus 로고    scopus 로고
    • Identification of pro-angiogenic markers in blood vessels from stroked-affected brain tissue using laser-capture microdissection
    • Slevin M, Krupinski J, Rovira N, Turu M, Luque A, Baldellou M, Sanfeliu C, de Vera N and Badimon L: Identification of pro-angiogenic markers in blood vessels from stroked-affected brain tissue using laser-capture microdissection. BMC Genomics 10: 113, 2009.
    • (2009) BMC Genomics , vol.10 , pp. 113
    • Slevin, M.1    Krupinski, J.2    Rovira, N.3    Turu, M.4    Luque, A.5    Baldellou, M.6    Sanfeliu, C.7    De Vera, N.8    Badimon, L.9
  • 26
    • 84894482142 scopus 로고    scopus 로고
    • Autophagy facilitates TLR4-and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination
    • Zhan Z, Xie X, Cao H, Zhou X, Zhang XD, Fan H and Liu Z: Autophagy facilitates TLR4-and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination. Autophagy 10: 257-268, 2014.
    • (2014) Autophagy , vol.10 , pp. 257-268
    • Zhan, Z.1    Xie, X.2    Cao, H.3    Zhou, X.4    Zhang, X.D.5    Fan, H.6    Liu, Z.7
  • 30
    • 57449120942 scopus 로고    scopus 로고
    • Autophagy-induced tumor dormancy in ovarian cancer
    • Amaravadi RK: Autophagy-induced tumor dormancy in ovarian cancer. J Clin Invest 118: 3837-3840, 2008.
    • (2008) J Clin Invest , vol.118 , pp. 3837-3840
    • Amaravadi, R.K.1
  • 34
    • 34547204160 scopus 로고    scopus 로고
    • The MEK/ERK cascade: From signaling specificity to diverse functions
    • Shaul YD and Seger R: The MEK/ERK cascade: From signaling specificity to diverse functions. Biochim Biophys Acta 1773: 1213-1226, 2007.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1213-1226
    • Shaul, Y.D.1    Seger, R.2
  • 35
    • 69249153394 scopus 로고    scopus 로고
    • A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1
    • Wang J, Whiteman MW, Lian H, Wang G, Singh A, Huang D and Denmark T: A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. J Biol Chem 284: 21412-21424, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 21412-21424
    • Wang, J.1    Whiteman, M.W.2    Lian, H.3    Wang, G.4    Singh, A.5    Huang, D.6    Denmark, T.7
  • 36
    • 73649089980 scopus 로고    scopus 로고
    • ERK and cell death: Mechanisms of ERK-induced cell death-apoptosis, autophagy and senescence
    • Cagnol S and Chambard JC: ERK and cell death: Mechanisms of ERK-induced cell death-apoptosis, autophagy and senescence. FEBS J 277: 2-21, 2010.
    • (2010) FEBS J , vol.277 , pp. 2-21
    • Cagnol, S.1    Chambard, J.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.