Efficacy of 2 grammes of intravenous transexamic acid in the reduction of post-surgical bleeding after total hip and knee replacement;Eficacia de 2 gramos intravenosos de ácido tranexámico en la reducción del sangrado postoperatorio de la artroplastia total de cadera y rodilla

Revista Espanola de Cirugia Ortopedica y Traumatologia

Volumn 60, Issue 5, 2016, Pages 315-324

  Castro Menendez M ^a   Pena Paz, S ^b   Rocha Garcia F ^a   Rodriguez Casas N ^a   Huici Izco, R ^a   Montero Vieites A ^a  

^a Hospital de Monforte de Lemos   (Spain)

^b Hospital Lucus Augusta   (Spain)

Author keywords

Blood loss; Thromboembolic complications; Tranexamic acid; Transfusion

Indexed keywords

ANTIFIBRINOLYTIC AGENT; TRANEXAMIC ACID;

ADULT; AGED; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ADMINISTRATION; FEMALE; FOLLOW UP; HIP REPLACEMENT; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; KNEE REPLACEMENT; MALE; MIDDLE AGED; POSTOPERATIVE HEMORRHAGE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANTIFIBRINOLYTIC AGENTS; ARTHROPLASTY, REPLACEMENT, HIP; ARTHROPLASTY, REPLACEMENT, KNEE; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; POSTOPERATIVE HEMORRHAGE; PROSPECTIVE STUDIES; TRANEXAMIC ACID; TREATMENT OUTCOME;

EID: 84992213706     PISSN: 18884415     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.recot.2016.05.001     Document Type: Article

References (29)

1. 1 Canillas, F., Gómez-Ramírez, S., Garcia-Erce, J.A., Pavia-Molina, J., Gomez-Luque, A., Muñoz, M., “Patient blood management” en cirugía ortopédica. Rev Esp Cir Ortop Traumatol. 59 (2015), 137–149.
2. 2 Spahn, D.R., Anemia and patient blood management in hip and knee surgery: a systematic review of the literature. Anesthesiology 113 (2010), 482–495.
3. 3 Springer Bryan, D., Odum Susan, M., Fehring Thomas, K., What is the benefit of tranexamic acid vs. reinfusion drains in total joint arthroplasty?. J Arthroplas., 2015, 10.1016/j.arth.2015.08.006.
4. 4 Gillette, B.P., DeSimone, L.J., Trousdale, R.T., Pagnano, M.W., Sierra, R.J., Low risk of thromboembolic complications with tranexamic acid after primary total hip and knee arthroplasty. Clin Orthop Relat Res. 471 (2013), 150–154.
5. 5 Aguilera-Roiga, X., Jordán-Salesa, M., Natera-Cisnerosa, L., Monllau-Garcíaa, J.C., Martínez-Zapata, M.J., Ácido tranexámico en cirugía ortopédica. Rev Esp Cir Ortop Traumatol. 58 (2014), 52–56.
6. 6 Poeran, J., Rasul, R., Suzuki, S., Danninger, T., Mazumdar, M., Opperer, M., et al. Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety. BMJ., 349, 2014, g4829, 10.1136/bmj.g4829.
7. 7 Cid, J., Lozano, M., Tranexamic acid reduces allogeneic red cell transfusions in patients undergoing total knee arthroplasty: results of a meta-analysis of randomized controlled trials. Transfusion. 45 (2005), 1302–1307.
8. 8 Ho, K.M., Ismail, H., Use of intravenous tranexamic acid to reduce allogeneic blood transfusion in total hip and knee arthroplasty: a meta-analysis. Anaesth Intensive Care. 31 (2003), 529–537.
9. 9 Zufferey, P., Merquiol, F., Laporte, S., Decousus, H., Mismetti, P., Auboyer, C., et al. Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery?. Anesthesiology. 105 (2006), 1034–1046.
10. 10 Huang, F., Wu, D., Ma, G., Yin, Z., Wang, Q., The use of tranexamic acid to reduce blood loss and transfusion in major orthopedic surgery: a meta-analysis. J Surg Res. 186 (2014), 318–327.
11. 11 Zhou, X.D., Tao, L.J., Li, J., Wu, L.D., Do we really need tranexamic acid in total hip arthroplasty? A meta-analysis of nineteen randomized controlled trials. Arch Orthop Trauma Surg. 133 (2013), 1017–1027.
12. 12 Oremus, K., Sostaric, S., Trkulja, V., Haspl, M., Influence of tranexamic acid on postoperative autologous blood retransfusion in primary total hip and knee arthroplasty: a randomized controlled trial. Transfusion. 54 (2014), 31–41.
13. 13 Ker, K., Edwards, P., Perel, P., Shakur, H., Roberts, I., Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis. BMJ., 344, 2012, e3054.
14. 14 Yang, Z.G., Chen, W.P., Wu, L.D., Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis. J Bone Joint Surg Am. 94 (2012), 1153–1159.
15. 15 Leal-Noval, S.R., Muñoz, M., Asuero, M., Contreras, E., García-Erce, J.A., Llau, J.V., et al. Documento Sevilla de Consenso sobre alternativas a la transfusión de sangre alogénica. Actualización del Documento Sevilla. Rev Esp Anestesiol Reanim., 60, 2013 263.e1-25.
16. 16 Hourlier, H., Fennema, P., Single tranexamic acid dose to reduce perioperative morbidity in primary total hip replacement: a randomised clinical trial. Hip Int. 24 (2014), 63–68.
17. 17 American Society of Anesthesiologists. New classification of physical status. Anesthesiology., 24, 1963, 111.
18. 18 Gross, J.B., Estimating allowable blood loss: Corrected for dilution. Anesthesiology. 58 (1983), 277–280.
19. 19 American Society of Anesthesiologists task force on perioperative blood transfusion, adjuvant therapies. Practice guidelines for perioperative blood transfusion and adjuvant therapies: an updated report. Anesthesiology. 105 (2006), 198–208.
20. 20 Gilcher, R.O., Belcher, A.J., Predeposit programs. Sander, G., Silvergleid, A.J., (eds.) Autologous transfusion., 1983, American Association of Blood Banks, Arlington, VA, 11–22.
21. 21 Oremus, K., Tranexamic acid for the reduction of blood loss in total knee arthroplasty. Ann Transl Med., 3(S1), 2015, S40.
22. 22 Kozek-Langenecker, S.A., Afshari, A., Albaladejo, P., Santullano, C.A., de Robertis, E., Filipescu, D.C., et al. Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology. Eur J Anesthesiol. 30 (2013), 270–382.
23. 23 AAOS. Surgical management of osteoarthritis of the knee. Evidence-based clinical practice guideline [consultado 12 Abr 2015]. Disponible en: http://www.aaos.org/uploadedFiles/PreProduction/Quality/Guidelines_and_Reviews/SMOAK%20CPG_12.4.15.pdf.
24. 24 Hsu, C.H., Lin, P.C., Kuo, F.C., Wang, J.W., A regime of two intravenous injections of tranexamic acid reduces blood loss in minimally invasive total hip arthroplasty. Bone Joint J. 97–B (2015), 905–910.
25. 25 Rajesparan, K., Biant, L.C., Ahmad, M., Field, R.E., The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement. J Bone Joint Surg [Br]. 91–B (2009), 776–783.
26. 26 Benoni, G., Fredin, H., Knebel, R., Nilsson, P., Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations. Acta Orthop Scand. 72 (2001), 442–448.
27. 27 Barr, P.J., Donnelly, M., Cardwell, C., Alam, S.S., Morris, K., Parker, M., et al. Drivers of transfusion decision making and quality of the evidence in orthopedic surgery: a systematic review of the literature. Transfus Med Rev. 25 (2011), 304–316.
28. 28 Shahryar Noordin, S., Waters, T.S., Garbuz, D.S., Duncan, C.P., Masri, B.A., Tranexamic acid reduces allogenic transfusion in revision hip arthroplasty. Clin Orthop Relat Res. 469 (2011), 541–546.
29. 29 Carling, M.S., Jeppsson, A., Eriksson, B.I., Brisby, H., Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study. J Orthop Surg Res, 10, 2015, 48.