-
1
-
-
84919432580
-
Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials
-
1 Emberson, J, Lees, KR, Lyden, P, et al. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet 384 (2014), 1929–1935.
-
(2014)
Lancet
, vol.384
, pp. 1929-1935
-
-
Emberson, J.1
Lees, K.R.2
Lyden, P.3
-
2
-
-
84906706030
-
Questions about authorisation of alteplase for ischaemic stroke
-
2 Shinton, R, Questions about authorisation of alteplase for ischaemic stroke. Lancet 384 (2014), 659–660.
-
(2014)
Lancet
, vol.384
, pp. 659-660
-
-
Shinton, R.1
-
3
-
-
84926171914
-
Thrombolysis in acute ischaemic stroke: time for a rethink?
-
3 Alper, BS, Malone-Moses, M, McLellan, JS, Prasad, K, Manheimer, E, Thrombolysis in acute ischaemic stroke: time for a rethink?. BMJ, 350, 2015, h1075.
-
(2015)
BMJ
, vol.350
, pp. h1075
-
-
Alper, B.S.1
Malone-Moses, M.2
McLellan, J.S.3
Prasad, K.4
Manheimer, E.5
-
4
-
-
84992208544
-
Alteplase for treatment of acute ischaemic stroke: independent review
-
(accessed July 24, 2015).
-
4 Medicines and Healthcare products Regulatory Agency. Alteplase for treatment of acute ischaemic stroke: independent review. https://www.gov.uk/government/publications/alteplase-for-treatment-of-acute-ischaemic-stroke-independent-review, 2015 (accessed July 24, 2015).
-
(2015)
-
-
-
5
-
-
84878213488
-
Details of a prospective protocol for a collaborative meta-analysis of individual participant data from all randomized trials of intravenous rt-PA vs. control: statistical analysis plan for the Stroke Thrombolysis Trialists' Collaborative meta-analysis
-
5 The Stroke Thrombolysis Trialists' Collaborative Group. Details of a prospective protocol for a collaborative meta-analysis of individual participant data from all randomized trials of intravenous rt-PA vs. control: statistical analysis plan for the Stroke Thrombolysis Trialists' Collaborative meta-analysis. Int J Stroke 8 (2013), 278–283.
-
(2013)
Int J Stroke
, vol.8
, pp. 278-283
-
-
-
6
-
-
84862629039
-
Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis
-
6 Wardlaw, JM, Murray, V, Berge, E, et al. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet 379 (2013), 2364–2372.
-
(2013)
Lancet
, vol.379
, pp. 2364-2372
-
-
Wardlaw, J.M.1
Murray, V.2
Berge, E.3
-
7
-
-
33846347159
-
Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study
-
7 Wahlgren, N, Ahmed, N, Davalos, A, et al. Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet 369 (2007), 275–282.
-
(2007)
Lancet
, vol.369
, pp. 275-282
-
-
Wahlgren, N.1
Ahmed, N.2
Davalos, A.3
-
8
-
-
0029050323
-
Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke
-
8 Hacke, W, Kaste, M, Fieschi, C, et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. JAMA 274 (1995), 1017–1025.
-
(1995)
JAMA
, vol.274
, pp. 1017-1025
-
-
Hacke, W.1
Kaste, M.2
Fieschi, C.3
-
9
-
-
84862625338
-
The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial
-
9 IST-3 collaborative group. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet 379 (2012), 2352–2363.
-
(2012)
Lancet
, vol.379
, pp. 2352-2363
-
-
-
10
-
-
40949161352
-
Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial
-
10 Davis, SM, Donnan, GA, Parsons, MW, et al. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol 7 (2008), 299–309.
-
(2008)
Lancet Neurol
, vol.7
, pp. 299-309
-
-
Davis, S.M.1
Donnan, G.A.2
Parsons, M.W.3
-
11
-
-
0028783948
-
Tissue plasminogen activator for acute ischemic stroke
-
11 The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 333 (1995), 1581–1588.
-
(1995)
N Engl J Med
, vol.333
, pp. 1581-1588
-
-
-
12
-
-
0032541845
-
Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II)
-
12 Hacke, W, Kaste, M, Fieschi, C, et al. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Lancet 352 (1998), 1245–1251.
-
(1998)
Lancet
, vol.352
, pp. 1245-1251
-
-
Hacke, W.1
Kaste, M.2
Fieschi, C.3
-
13
-
-
52649165720
-
Thrombolysis with alteplase 3 to 4·5 hours after acute ischemic stroke
-
13 Hacke, W, Kaste, M, Bluhmki, E, et al. Thrombolysis with alteplase 3 to 4·5 hours after acute ischemic stroke. N Engl J Med 359 (2008), 1317–1329.
-
(2008)
N Engl J Med
, vol.359
, pp. 1317-1329
-
-
Hacke, W.1
Kaste, M.2
Bluhmki, E.3
-
14
-
-
0036158585
-
ATLANTIS trial: results for patients treated within 3 hours of stroke onset. Alteplase thrombolysis for acute noninterventional therapy in ischemic stroke
-
14 Albers, GW, Clark, WM, Madden, KP, Hamilton, SA, ATLANTIS trial: results for patients treated within 3 hours of stroke onset. Alteplase thrombolysis for acute noninterventional therapy in ischemic stroke. Stroke 33 (2002), 493–495.
-
(2002)
Stroke
, vol.33
, pp. 493-495
-
-
Albers, G.W.1
Clark, W.M.2
Madden, K.P.3
Hamilton, S.A.4
-
15
-
-
0033485522
-
Recombinant tissue-type plasminogen activator (alteplase) for ischemic stroke 3 to 5 hours after symptom onset
-
15 Clark, WM, Wissman, S, Albers, GW, et al. Recombinant tissue-type plasminogen activator (alteplase) for ischemic stroke 3 to 5 hours after symptom onset. JAMA 282 (1999), 2019–2026.
-
(1999)
JAMA
, vol.282
, pp. 2019-2026
-
-
Clark, W.M.1
Wissman, S.2
Albers, G.W.3
-
16
-
-
0027264810
-
Pilot randomized trial of tissue plasminogen activator in acute ischemic stroke. The TPA Bridging Study Group
-
16 Haley, EC, Brott, TG, Sheppard, GL, et al. Pilot randomized trial of tissue plasminogen activator in acute ischemic stroke. The TPA Bridging Study Group. Stroke 24 (1993), 1000–1004.
-
(1993)
Stroke
, vol.24
, pp. 1000-1004
-
-
Haley, E.C.1
Brott, T.G.2
Sheppard, G.L.3
-
17
-
-
0026736173
-
Intravenous recombinant tissue plasminogen activator in acute carotid artery territory stroke
-
17 Mori, E, Yoneda, Y, Tabuchi, M, et al. Intravenous recombinant tissue plasminogen activator in acute carotid artery territory stroke. Neurology 42 (1992), 976–982.
-
(1992)
Neurology
, vol.42
, pp. 976-982
-
-
Mori, E.1
Yoneda, Y.2
Tabuchi, M.3
-
18
-
-
0242271890
-
Early intravenous thrombolysis with recombinant tissue plasminogen activator for acute cerebral infarction
-
18 Wang, S, Wang, X, Zeng, H, et al. Early intravenous thrombolysis with recombinant tissue plasminogen activator for acute cerebral infarction. Chinese Crit Care Med 15 (2003), 542–545.
-
(2003)
Chinese Crit Care Med
, vol.15
, pp. 542-545
-
-
Wang, S.1
Wang, X.2
Zeng, H.3
-
19
-
-
0000361818
-
Intravenous tissue plasminogen activator ameliorates the outcome of hyperacute embolic stroke
-
19 Yamaguchi, T, Hayakawa, T, Kiuchi, H, Intravenous tissue plasminogen activator ameliorates the outcome of hyperacute embolic stroke. Cerebrovasc Dis 3 (1993), 269–272.
-
(1993)
Cerebrovasc Dis
, vol.3
, pp. 269-272
-
-
Yamaguchi, T.1
Hayakawa, T.2
Kiuchi, H.3
-
20
-
-
77957994535
-
Intravenous thrombolysis plus hypothermia for acute treatment of ischemic stroke (ICTuS-L): final results
-
20 Hemmen, TM, Raman, R, Guluma, KZ, et al. Intravenous thrombolysis plus hypothermia for acute treatment of ischemic stroke (ICTuS-L): final results. Stroke 41 (2010), 2265–2270.
-
(2010)
Stroke
, vol.41
, pp. 2265-2270
-
-
Hemmen, T.M.1
Raman, R.2
Guluma, K.Z.3
-
21
-
-
84868209961
-
Risk factors for intracranial hemorrhage in acute ischemic stroke patients treated with recombinant tissue plasminogen activator: a systematic review and meta-analysis of 55 studies
-
21 Whiteley, WN, Slot, KB, Fernandes, P, et al. Risk factors for intracranial hemorrhage in acute ischemic stroke patients treated with recombinant tissue plasminogen activator: a systematic review and meta-analysis of 55 studies. Stroke 43 (2012), 2904–2909.
-
(2012)
Stroke
, vol.43
, pp. 2904-2909
-
-
Whiteley, W.N.1
Slot, K.B.2
Fernandes, P.3
-
22
-
-
0032499446
-
Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST)
-
22 European Carotid Surgery Trialists' Collaborative Group. Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST). Lancet 351 (1998), 1379–1387.
-
(1998)
Lancet
, vol.351
, pp. 1379-1387
-
-
-
23
-
-
0025734372
-
Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis
-
23 North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N Engl J Med 325 (1991), 445–453.
-
(1991)
N Engl J Med
, vol.325
, pp. 445-453
-
-
-
24
-
-
77449112420
-
Assessment and improvement of figures to visually convey benefit and risk of stroke thrombolysis
-
24 Gadhia, J, Starkman, S, Ovbiagele, B, Ali, L, Liebeskind, D, Saver, JL, Assessment and improvement of figures to visually convey benefit and risk of stroke thrombolysis. Stroke 41 (2010), 300–306.
-
(2010)
Stroke
, vol.41
, pp. 300-306
-
-
Gadhia, J.1
Starkman, S.2
Ovbiagele, B.3
Ali, L.4
Liebeskind, D.5
Saver, J.L.6
-
25
-
-
84924129268
-
Development of a computerised decision aid for thrombolysis in acute stroke care
-
25 Flynn, D, Nesbitt, DJ, Ford, GA, et al. Development of a computerised decision aid for thrombolysis in acute stroke care. BMC Med Inform Decis Mak, 15, 2015, 6.
-
(2015)
BMC Med Inform Decis Mak
, vol.15
, pp. 6
-
-
Flynn, D.1
Nesbitt, D.J.2
Ford, G.A.3
-
26
-
-
84945943352
-
Development and validation of a simplified stroke-thrombolytic predictive instrument
-
26 Kent, DM, Ruthazer, R, Decker, C, et al. Development and validation of a simplified stroke-thrombolytic predictive instrument. Neurology 85 (2015), 942–949.
-
(2015)
Neurology
, vol.85
, pp. 942-949
-
-
Kent, D.M.1
Ruthazer, R.2
Decker, C.3
-
27
-
-
84945964477
-
Patient-centered decision support in acute ischemic stroke: qualitative study of patients' and providers' perspectives
-
27 Decker, C, Chhatriwalla, E, Gialde, E, et al. Patient-centered decision support in acute ischemic stroke: qualitative study of patients' and providers' perspectives. Circ Cardiovasc Qual Outcomes 8 (2015), S109–S116.
-
(2015)
Circ Cardiovasc Qual Outcomes
, vol.8
, pp. S109-S116
-
-
Decker, C.1
Chhatriwalla, E.2
Gialde, E.3
-
28
-
-
84929454086
-
Thrombectomy within 8 hours after symptom onset in ischemic stroke
-
28 Jovin, TG, Chamorro, A, Cobo, E, et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 372 (2015), 2296–2306.
-
(2015)
N Engl J Med
, vol.372
, pp. 2296-2306
-
-
Jovin, T.G.1
Chamorro, A.2
Cobo, E.3
-
29
-
-
84924663845
-
Endovascular therapy for ischemic stroke with perfusion-imaging selection
-
29 Campbell, BCV, Mitchell, PJ, Kleinig, TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 372 (2015), 1009–1018.
-
(2015)
N Engl J Med
, vol.372
, pp. 1009-1018
-
-
Campbell, B.C.V.1
Mitchell, P.J.2
Kleinig, T.J.3
-
30
-
-
84920502575
-
A randomized trial of intraarterial treatment for acute ischemic stroke
-
30 Berkhemer, OA, Fransen, PSS, Beumer, D, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 372 (2014), 1009–1018.
-
(2014)
N Engl J Med
, vol.372
, pp. 1009-1018
-
-
Berkhemer, O.A.1
Fransen, P.S.S.2
Beumer, D.3
-
31
-
-
84924691962
-
Randomized assessment of rapid endovascular treatment of ischemic stroke
-
31 Goyal, M, Demchuk, AM, Menon, BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 372 (2015), 2285–2295.
-
(2015)
N Engl J Med
, vol.372
, pp. 2285-2295
-
-
Goyal, M.1
Demchuk, A.M.2
Menon, B.K.3
-
32
-
-
84930814840
-
Stent-Retriever Thrombectomy after intravenous t-PA vs. t-PA alone in stroke
-
32 Saver, JL, Goyal, M, Bonafe, A, et al. Stent-Retriever Thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 372 (2015), 2285–2295.
-
(2015)
N Engl J Med
, vol.372
, pp. 2285-2295
-
-
Saver, J.L.1
Goyal, M.2
Bonafe, A.3
-
33
-
-
84926419069
-
Alteplase versus tenecteplase for thrombolysis after ischaemic stroke (ATTEST): a phase 2, randomised, open-label, blinded endpoint study
-
33 Huang, X, Cheripelli, BK, Lloyd, SM, et al. Alteplase versus tenecteplase for thrombolysis after ischaemic stroke (ATTEST): a phase 2, randomised, open-label, blinded endpoint study. Lancet Neurol 14 (2015), 368–376.
-
(2015)
Lancet Neurol
, vol.14
, pp. 368-376
-
-
Huang, X.1
Cheripelli, B.K.2
Lloyd, S.M.3
-
34
-
-
84858685702
-
A randomized trial of tenecteplase versus alteplase for acute ischemic stroke
-
34 Parsons, M, Spratt, N, Bivard, A, et al. A randomized trial of tenecteplase versus alteplase for acute ischemic stroke. N Engl J Med 366 (2012), 1099–1107.
-
(2012)
N Engl J Med
, vol.366
, pp. 1099-1107
-
-
Parsons, M.1
Spratt, N.2
Bivard, A.3
-
35
-
-
84974844136
-
Low dose versus standard-dose intravenous alteplase in acute ischemic stroke
-
published online May 10.
-
35 Anderson, CS, Robinson, T, Lindley, R, et al. Low dose versus standard-dose intravenous alteplase in acute ischemic stroke. N Engl J Med, 2016, 10.1056/NEJMoa1515510 published online May 10.
-
(2016)
N Engl J Med
-
-
Anderson, C.S.1
Robinson, T.2
Lindley, R.3
-
36
-
-
84928059779
-
Association between brain imaging signs, early and late outcomes, and response to intravenous alteplase after acute ischaemic stroke in the third International Stroke Trial (IST-3): secondary analysis of a randomised controlled trial
-
36 IST-3 collaborative group. Association between brain imaging signs, early and late outcomes, and response to intravenous alteplase after acute ischaemic stroke in the third International Stroke Trial (IST-3): secondary analysis of a randomised controlled trial. Lancet Neurol 14 (2015), 485–496.
-
(2015)
Lancet Neurol
, vol.14
, pp. 485-496
-
-
-
37
-
-
84898994009
-
Prediction of stroke thrombolysis outcome using CT brain machine learning
-
37 Bentley, P, Ganesalingam, J, Carlton Jones, AL, et al. Prediction of stroke thrombolysis outcome using CT brain machine learning. Neuroimage Clin 4 (2014), 635–640.
-
(2014)
Neuroimage Clin
, vol.4
, pp. 635-640
-
-
Bentley, P.1
Ganesalingam, J.2
Carlton Jones, A.L.3
-
38
-
-
0034799451
-
Subgroup analyses in randomised controlled trials: quantifying the risks of false-positives and false-negatives
-
38 Brookes, ST, Whitley, E, Peters, TJ, Mulheran, PA, Egger, M, Davey Smith, G, Subgroup analyses in randomised controlled trials: quantifying the risks of false-positives and false-negatives. Health Technol Assess 5 (2001), 1–56.
-
(2001)
Health Technol Assess
, vol.5
, pp. 1-56
-
-
Brookes, S.T.1
Whitley, E.2
Peters, T.J.3
Mulheran, P.A.4
Egger, M.5
Davey Smith, G.6
-
39
-
-
84942886716
-
The Heidelberg bleeding classification
-
39 von Kummer, R, Broderick, JP, Campbell, BCV, et al. The Heidelberg bleeding classification. Stroke 46 (2015), 2981–2986.
-
(2015)
Stroke
, vol.46
, pp. 2981-2986
-
-
von Kummer, R.1
Broderick, J.P.2
Campbell, B.C.V.3
|