Development of a computerised decision aid for thrombolysis in acute stroke care

BMC Medical Informatics and Decision Making

Volumn 15, Issue 1, 2015, Pages

  Flynn, Darren ^a   Nesbitt, Daniel J ^b   Ford, Gary A ^a   McMeekin, Peter ^a   Rodgers, Helen ^a   Price, Christopher ^c   Kray, Christian ^d   Thomson, Richard G ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c WANSBECK GENERAL HOSPITAL   (United Kingdom)

^d UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Acute stroke; Decision aid; Decision support; Patient information; Risk communication; Shared decision making; Thrombolysis

Indexed keywords

CLINICAL DECISION MAKING; CLINICAL DECISION SUPPORT SYSTEM; DECISION SUPPORT SYSTEM; FEASIBILITY STUDY; FIBRINOLYTIC THERAPY; HUMAN; MEDICAL INFORMATICS; PILOT STUDY; PROCEDURES; STROKE;

CLINICAL DECISION-MAKING; DECISION SUPPORT SYSTEMS, CLINICAL; DECISION SUPPORT TECHNIQUES; FEASIBILITY STUDIES; HUMANS; MEDICAL INFORMATICS APPLICATIONS; PILOT PROJECTS; STROKE; THROMBOLYTIC THERAPY;

EID: 84924129268     PISSN: None     EISSN: 14726947     Source Type: Journal    
DOI: 10.1186/s12911-014-0127-1     Document Type: Article

References (39)

1. Wardlaw JM, Murray V, Berge E, Del Zoppo G, Sandercock P, Lindley RL, et al. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet. 2012;379:2364-72.
2. Lansberg MG, Albers GW, Wijman CA. Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors. Cerebrovasc Dis. 2007;24:1-10.
3. Murtagh MJ, Burges Watson DL, Jenkings KN, Lie ML, Mackintosh JE, Ford GA, et al. Situationally-sensitive knowledge translation and relational decision making in hyperacute stroke: a qualitative study. PLoS One. 2012;7(6):e37066. doi: 10.1371/journal.pone.0037066.
4. Hacke W, Kaste M, Bluhmki E, Brozman M, Dávalos A, Guidetti D, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. New Engl J of Med. 2008;359:1317-29.
5. Lees KR, Bluhmki E, Kummer R, Brott TG, Toni D, Grotta JC, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS and EPITHET trials. Lancet. 2010;375:1695-703.
6. Flynn D, Ford GA, Stobbart L, Rodgers H, Murtagh MJ, Thomson RG. A review of decision support, risk communication and patient information tools for thrombolytic treatment in acute stroke: lessons for tool developers. BMC Health Serv Res. 2013;13(1):225. doi: 10.1186/1472-6963-13-225.
7. Safe Implementation of Treatment - International Stroke Thrombolysis Registry. [https://sitsinternational.org/]
8. Wahlgren N, Ahmed N, Dávalos A, Ford GA, Grond M, Hacke W, et al. Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet. 2007;369:275-82.
9. Lecouturier J, Murtagh MJ, Thomson RG, Ford GA, White M, Eccles M, et al. Response to symptoms of stroke in the UK: a systematic review. BMC Health Serv Res. 2010;10:157. doi: 10.1186/1472-6963-10-157.
10. National Audit Office. Progress in improving stroke care: a good practice guide. London: National Audit Office; 2010.
11. Albers GW, Olivot JM. Intravenous alteplase for ischaemic stroke. Lancet. 2007;369:249-50.
12. Intercollegiate Stroke Working Party: Stroke Improvement National Audit Programme (SINAP). Public Comprehensive Report 2012. [http://www.rcplondon. ac.uk/sites/default/files/sinap-comprehensive-public-report-2012.pdf]
13. Kwan J, Hand P, Sandercock P. A systematic review of barriers to delivery of thrombolysis for acute stroke. Age Ageing. 2004;33:116-21.
14. Brown DL, Barsan WG, Lisabeth LD, Gallery ME, Morgenstern LB. Survey of emergency physicians about recombinant tissue plasminogen activator for acute ischemic stroke. Ann Emerg Med. 2005;46:56-60.
15. Dirks M, Niessen LW, Koudstaal PJ, Franke CL, Van Oostenbrugge RJ, Dippel DW. Intravenous thrombolysis in acute ischaemic stroke: from trial exclusion criteria to clinical contraindications. An international Delphi study. J Neurol Neurosurg Psychiatry. 2007;78:685-9.
16. Wardlaw JM, Murray V, Berge E, Del Zoppo GJ. Thrombolysis for acute ischaemic stroke. Cochrane Database Syst Rev. 2009;4: CD000213.
17. Stacey D, Bennett CL, Barry MJ, Col NF, Eden KB, Holmes-Rovner M, et al. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev. 2011;10: CD001431. doi: 10.1002/14651858. CD001431.pub3.
18. Eissa A, Krass I, Bajorek BV. Barriers to the utilization of thrombolysis for acute ischaemic stroke. J Clin Pharm Ther. 2012;37:399-409.
19. Flynn D, Pierce M, Hess E, Murad MH, Erwin PJ, Montori VM, et al. Engaging patients in healthcare decisions in the emergency department through shared decision making: a systematic review. Acad Emerg Med. 2012;19:959-67.
20. Mangset M, Berge E, Førde R, Nessa J, Wyller TB. "Two per cent isn't a lot, but when it comes to death it seems quite a lot anyway": patients' perception of risk and willingness to accept risks associated with thrombolytic drug treatment for acute stroke. J Med Ethics. 2009;35:42-6.
21. Bruins Slot K, Berge E. Thrombolytic treatment for stroke: patient preferences for treatment, information and involvement. J Stroke Cerebrovasc Dis. 2009;18:17-22.
22. Solomon NA, Glick HA, Russo CJ, Lee J, Schulman KA. Patient preferences for stroke outcomes. Stroke. 1994;25:1721-5.
23. Campbell M, Fitzpatrick R, Haines A, Kinmonth AL, Sandercock P, Spiegelhalter D, et al. Framework for design and evaluation of complex interventions to improve health. Brit Med J. 2000;321:694-6.
24. Elwyn G, Kreuwel I, Durand MA, Sivell S, Joseph-Williams N, Evans R, et al. How to develop web-based decision support interventions for patients: a process map. Patient Educ Couns. 2011;82:260-5.
25. McMeekin P, Flynn D, Ford GA, Rodgers H, Gray J, Thomson RG: Development of a decision analytic model to support decision-making and risk communication about thrombolytic treatment. BMC Med Inform Decis Mak 2014 (under review).
26. Kent D, Selker HP, Ruthazer R, Bluhmki E, Hacke W. The Stroke-Thrombolytic Predictive Instrument: a predictive instrument for intravenous thrombolysis in acute ischemic stroke. Stroke. 2006;37:2957-62.
27. Uyttenboogaart M, Stewart RE, Vroomen PC, Luijckx GJ, De Keyser J. Utility of the stroke-thrombolytic predictive instrument. J Neurol Neurosurg Psychiatry. 2008;79:1079-81.
28. McMeekin P, Flynn D, Ford GA, Rodgers H, Thomson RG. Validating the Stroke-Thrombolytic Predictive Instrument in a Population in the United Kingdom. Stroke. 2012;43:3378-81.
29. Wahlgren N, Ahmed N, Eriksson N, Aichner F, Bluhmki E, Dávalos A, et al. Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials safe implementation of thrombolysis in stroke-monitoring study (SITS-MOST). Stroke. 2008;39:3316-22.
30. Ali M, Bath P, Brady M, Davis S, Diener HC, Donnan G, et al. Development, expansion and use of a stroke clinical trials resource for novel exploratory analyses. Int J Stroke. 2012;7:133-8.
31. Mazya M, Egido JA, Ford GA, Lees KR, Mikulik R, Toni D, et al. Predicting the risk of symptomatic intracerebral hemorrhage in ischemic stroke treated with intravenous alteplase: safe implementation of treatments in stroke (SITS) symptomatic intracerebral hemorrhage risk score. Stroke. 2012;43:1524-31.
32. Cucchiara B, Kasner SE, Tanne D. Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke: pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) 1 and SAINT II trials. Stroke. 2009;40:3067-72.
33. International Patient Decision Aid Standards (IPDAS) Collaboration: 2012 Update of the IPDAS Collaboration Background Document. [http://ipdas. ohri.ca/resources.html]
34. Galitz WO. The essential guide to user interface design: an introduction to GUI design principles and techniques. 3rd ed. Indianapolis, IN: Wiley Publishing Inc; 2007.
35. Snyder C Paper prototyping: The fast and easy way to design and refine user interfaces. San Francisco, CA: Morgan Kaufman Publishers; 2003.
36. Krippendorff K. Content analysis: an introduction to its methodology. 2nd ed. Thousand Oaks, CA: Sage; 2004.
37. National Institute of Neurological Disorders and Stroke/National Institutes of Health: National Institutes of Health Stroke Scale. [http://www.ninds.nih.gov/disorders/stroke/strokescales.htm]
38. Hawley ST, Zikmund-Fisher BJ, Ubel PA, Jancovic A, Lucas T, Fagerlin A. The impact of the format of graphical presentation on health-related knowledge and treatment choices. Patient Educ Couns. 2008;73:448-55.
39. Elwyn G, Laitner S, Coulter A, Walker E, Watson P, Thomson R. Implementing shared decision making in the NHS. Brit Med J. 2010;341:971-3.