메뉴 건너뛰기




Volumn 7, Issue 4, 2016, Pages 693-706

ESC-Derived BDNF-Overexpressing Neural Progenitors Differentially Promote Recovery in Huntington's Disease Models by Enhanced Striatal Differentiation

Author keywords

brain derived neurotrophic factor; embryonic stem cells; Huntington's disease; striatal differentiation

Indexed keywords

ASPARTOACYLASE; BRAIN DERIVED NEUROTROPHIC FACTOR; BROXURIDINE; FORKHEAD TRANSCRIPTION FACTOR; QUINOLINIC ACID; TRANSCRIPTION FACTOR FOXP1; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

EID: 84992187922     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2016.08.018     Document Type: Article
Times cited : (30)

References (39)
  • 1
    • 55949130712 scopus 로고    scopus 로고
    • Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats
    • Aubry, L., Bugi, A., Lefort, N., Rousseau, F., Peschanski, M., Perrier, A.L., Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats. Proc. Natl. Acad. Sci. USA 105 (2008), 16707–16712.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 16707-16712
    • Aubry, L.1    Bugi, A.2    Lefort, N.3    Rousseau, F.4    Peschanski, M.5    Perrier, A.L.6
  • 3
    • 58149198246 scopus 로고    scopus 로고
    • Lesion-induced increase in survival and migration of human neural progenitor cells releasing GDNF
    • Behrstock, S., Ebert, A.D., Klein, S., Schmitt, M., Moore, J.M., Svendsen, C.N., Lesion-induced increase in survival and migration of human neural progenitor cells releasing GDNF. Cell Transplant. 12 (2008), 753–762.
    • (2008) Cell Transplant. , vol.12 , pp. 753-762
    • Behrstock, S.1    Ebert, A.D.2    Klein, S.3    Schmitt, M.4    Moore, J.M.5    Svendsen, C.N.6
  • 4
    • 33751087210 scopus 로고    scopus 로고
    • Neural cell adhesion molecule L1-transfected embryonic stem cells promote functional recovery after excitotoxic lesion of the mouse striatum
    • Bernreuther, C., Dihne, M., Johann, V., Schiefer, J., Cui, Y., Hargus, G., Schmid, J.S., Xu, J., Kosinski, C.M., Schachner, M., Neural cell adhesion molecule L1-transfected embryonic stem cells promote functional recovery after excitotoxic lesion of the mouse striatum. J. Neurosci. 26 (2006), 11532–11539.
    • (2006) J. Neurosci. , vol.26 , pp. 11532-11539
    • Bernreuther, C.1    Dihne, M.2    Johann, V.3    Schiefer, J.4    Cui, Y.5    Hargus, G.6    Schmid, J.S.7    Xu, J.8    Kosinski, C.M.9    Schachner, M.10
  • 5
    • 77952888250 scopus 로고    scopus 로고
    • The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease
    • Buckley, N.J., Johnson, R., Zuccato, C., Bithell, A., Cattaneo, E., The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease. Neurobiol. Dis. 39 (2010), 28–39.
    • (2010) Neurobiol. Dis. , vol.39 , pp. 28-39
    • Buckley, N.J.1    Johnson, R.2    Zuccato, C.3    Bithell, A.4    Cattaneo, E.5
  • 7
    • 77957727491 scopus 로고    scopus 로고
    • Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma
    • Chiang, M., Chen, C., Lee, M., Chen, H., Chen, H., Wu, Y., Hung, C., Kang, J., Chang, C., Chang, C., et al. Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma. Hum. Mol. Genet. 19 (2010), 4043–4058.
    • (2010) Hum. Mol. Genet. , vol.19 , pp. 4043-4058
    • Chiang, M.1    Chen, C.2    Lee, M.3    Chen, H.4    Chen, H.5    Wu, Y.6    Hung, C.7    Kang, J.8    Chang, C.9    Chang, C.10
  • 9
    • 84960082333 scopus 로고    scopus 로고
    • AAV-mediated BDNF gene therapy in a transgenic rat model of Huntington's disease
    • Connor, B., Sun, Y., von, H.D., Tang, S.K., Jones, K.S., Maucksch, C., AAV-mediated BDNF gene therapy in a transgenic rat model of Huntington's disease. Gene Ther. 23 (2016), 283–295.
    • (2016) Gene Ther. , vol.23 , pp. 283-295
    • Connor, B.1    Sun, Y.2    von, H.D.3    Tang, S.K.4    Jones, K.S.5    Maucksch, C.6
  • 10
    • 79551551522 scopus 로고    scopus 로고
    • Subregional specification of embryonic stem cell-derived ventral telencephalic tissues by timed and combinatory treatment with extrinsic signals
    • Danjo, T., Eiraku, M., Muguruma, K., Watanabe, K., Kawada, M., Yanagawa, Y., Rubenstein, J.L., Sasai, Y., Subregional specification of embryonic stem cell-derived ventral telencephalic tissues by timed and combinatory treatment with extrinsic signals. J. Neurosci. 31 (2011), 1919–1933.
    • (2011) J. Neurosci. , vol.31 , pp. 1919-1933
    • Danjo, T.1    Eiraku, M.2    Muguruma, K.3    Watanabe, K.4    Kawada, M.5    Yanagawa, Y.6    Rubenstein, J.L.7    Sasai, Y.8
  • 11
    • 84871586691 scopus 로고    scopus 로고
    • Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons
    • Delli, C.A., Onorati, M., Lelos, M.J., Castiglioni, V., Faedo, A., Menon, R., Camnasio, S., Vuono, R., Spaiardi, P., Talpo, F., et al. Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons. Development 140 (2013), 301–312.
    • (2013) Development , vol.140 , pp. 301-312
    • Delli, C.A.1    Onorati, M.2    Lelos, M.J.3    Castiglioni, V.4    Faedo, A.5    Menon, R.6    Camnasio, S.7    Vuono, R.8    Spaiardi, P.9    Talpo, F.10
  • 12
    • 77953701829 scopus 로고    scopus 로고
    • Ex vivo delivery of GDNF maintains motor function and prevents neuronal loss in a transgenic mouse model of Huntington's disease
    • Ebert, A.D., Barber, A.E., Heins, B.M., Svendsen, C.N., Ex vivo delivery of GDNF maintains motor function and prevents neuronal loss in a transgenic mouse model of Huntington's disease. Exp. Neurol. 224 (2010), 155–162.
    • (2010) Exp. Neurol. , vol.224 , pp. 155-162
    • Ebert, A.D.1    Barber, A.E.2    Heins, B.M.3    Svendsen, C.N.4
  • 13
    • 84869502180 scopus 로고    scopus 로고
    • Implantation of undifferentiated and pre-differentiated human neural stem cells in the R6/2 transgenic mouse model of Huntington's disease
    • El-Akabawy, G., Rattray, I., Johansson, S.M., Gale, R., Bates, G., Modo, M., Implantation of undifferentiated and pre-differentiated human neural stem cells in the R6/2 transgenic mouse model of Huntington's disease. BMC. Neurosci., 13, 2012, 97.
    • (2012) BMC. Neurosci. , vol.13 , pp. 97
    • El-Akabawy, G.1    Rattray, I.2    Johansson, S.M.3    Gale, R.4    Bates, G.5    Modo, M.6
  • 15
  • 18
    • 65449167971 scopus 로고    scopus 로고
    • Short-term striatal gene expression responses to brain-derived neurotrophic factor are dependent on MEK and ERK activation
    • Gokce, O., Runne, H., Kuhn, A., Luthi-Carter, R., Short-term striatal gene expression responses to brain-derived neurotrophic factor are dependent on MEK and ERK activation. PLoS One, 4, 2009, e5292.
    • (2009) PLoS One , vol.4 , pp. e5292
    • Gokce, O.1    Runne, H.2    Kuhn, A.3    Luthi-Carter, R.4
  • 19
    • 0033168977 scopus 로고    scopus 로고
    • Expression of the striatal DARPP-32/ARPP-21 phenotype in GABAergic neurons requires neurotrophins in vivo and in vitro
    • Ivkovic, S., Ehrlich, M.E., Expression of the striatal DARPP-32/ARPP-21 phenotype in GABAergic neurons requires neurotrophins in vivo and in vitro. J. Neurosci. 19 (1999), 5409–5419.
    • (1999) J. Neurosci. , vol.19 , pp. 5409-5419
    • Ivkovic, S.1    Ehrlich, M.E.2
  • 20
    • 0021966828 scopus 로고
    • The gait abnormality of Huntington's disease
    • Koller, W.C., Trimble, J., The gait abnormality of Huntington's disease. Neurology 35 (1985), 1450–1454.
    • (1985) Neurology , vol.35 , pp. 1450-1454
    • Koller, W.C.1    Trimble, J.2
  • 21
    • 0025761794 scopus 로고
    • Development of intrastriatal striatal grafts and their afferent innervation from the host
    • Labandeira-Garcia, J.L., Wictorin, K., Cunningham, E.T. Jr., Bjorklund, A., Development of intrastriatal striatal grafts and their afferent innervation from the host. Neuroscience 42 (1991), 407–426.
    • (1991) Neuroscience , vol.42 , pp. 407-426
    • Labandeira-Garcia, J.L.1    Wictorin, K.2    Cunningham, E.T.3    Bjorklund, A.4
  • 22
    • 8844220536 scopus 로고    scopus 로고
    • Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series
    • Landles, C., Bates, G.P., Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series. EMBO Rep. 5 (2004), 958–963.
    • (2004) EMBO Rep. , vol.5 , pp. 958-963
    • Landles, C.1    Bates, G.P.2
  • 23
    • 84887594030 scopus 로고    scopus 로고
    • Embryonic stem cells stably expressing BDNF-GFP exhibit a BDNF-release-dependent enhancement of neuronal differentiation
    • Leschik, J., Eckenstaler, R., Nieweg, K., Lichtenecker, P., Brigadski, T., Gottmann, K., Lessmann, V., Lutz, B., Embryonic stem cells stably expressing BDNF-GFP exhibit a BDNF-release-dependent enhancement of neuronal differentiation. J. Cell Sci. 126 (2013), 5062–5073.
    • (2013) J. Cell Sci. , vol.126 , pp. 5062-5073
    • Leschik, J.1    Eckenstaler, R.2    Nieweg, K.3    Lichtenecker, P.4    Brigadski, T.5    Gottmann, K.6    Lessmann, V.7    Lutz, B.8
  • 24
    • 84862777143 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice
    • Ma, L., Hu, B., Liu, Y., Vermilyea, S.C., Liu, H., Gao, L., Sun, Y., Zhang, X., Zhang, S.C., Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice. Cell Stem Cell 10 (2012), 455–464.
    • (2012) Cell Stem Cell , vol.10 , pp. 455-464
    • Ma, L.1    Hu, B.2    Liu, Y.3    Vermilyea, S.C.4    Liu, H.5    Gao, L.6    Sun, Y.7    Zhang, X.8    Zhang, S.C.9
  • 25
    • 0035748688 scopus 로고    scopus 로고
    • Huntington's disease. Expanding horizons for treatment
    • McMurray, C.T., Huntington's disease. Expanding horizons for treatment. Lancet, 358(Suppl), 2001, S37.
    • (2001) Lancet , vol.358 , pp. S37
    • McMurray, C.T.1
  • 26
    • 77955936385 scopus 로고    scopus 로고
    • BDNF/MAPK/ERK-induced BMP7 expression in the developing cerebral cortex induces premature radial glia differentiation and impairs neuronal migration
    • Ortega, J.A., Alcantara, S., BDNF/MAPK/ERK-induced BMP7 expression in the developing cerebral cortex induces premature radial glia differentiation and impairs neuronal migration. Cereb. Cortex 20 (2010), 2132–2144.
    • (2010) Cereb. Cortex , vol.20 , pp. 2132-2144
    • Ortega, J.A.1    Alcantara, S.2
  • 28
    • 36049044225 scopus 로고    scopus 로고
    • Animal models of Huntington's disease
    • Ramaswamy, S., McBride, J.L., Kordower, J.H., Animal models of Huntington's disease. ILAR. J. 48 (2007), 356–373.
    • (2007) ILAR. J. , vol.48 , pp. 356-373
    • Ramaswamy, S.1    McBride, J.L.2    Kordower, J.H.3
  • 30
    • 79959621517 scopus 로고    scopus 로고
    • Huntington's disease: from mutant huntingtin protein to neurotrophic factor therapy
    • Sari, Y., Huntington's disease: from mutant huntingtin protein to neurotrophic factor therapy. Int. J. Biomed. Sci. 7 (2011), 89–100.
    • (2011) Int. J. Biomed. Sci. , vol.7 , pp. 89-100
    • Sari, Y.1
  • 31
    • 84861654183 scopus 로고    scopus 로고
    • GABAergic neurons from mouse embryonic stem cells possess functional properties of striatal neurons in vitro, and develop into striatal neurons in vivo in a mouse model of Huntington's disease
    • Shin, E., Palmer, M.J., Li, M., Fricker, R.A., GABAergic neurons from mouse embryonic stem cells possess functional properties of striatal neurons in vitro, and develop into striatal neurons in vivo in a mouse model of Huntington's disease. Stem Cell Rev. 8 (2012), 513–531.
    • (2012) Stem Cell Rev. , vol.8 , pp. 513-531
    • Shin, E.1    Palmer, M.J.2    Li, M.3    Fricker, R.A.4
  • 32
    • 77949631994 scopus 로고    scopus 로고
    • Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease
    • Snyder, B.R., Chiu, A.M., Prockop, D.J., Chan, A.W., Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease. PLoS One, 5, 2010, e9347.
    • (2010) PLoS One , vol.5 , pp. e9347
    • Snyder, B.R.1    Chiu, A.M.2    Prockop, D.J.3    Chan, A.W.4
  • 33
    • 3242700600 scopus 로고    scopus 로고
    • Neurogenesis in the striatum of the quinolinic acid lesion model of Huntington's disease
    • Tattersfield, A.S., Croon, R.J., Liu, Y.W., Kells, A.P., Faull, R.L., Connor, B., Neurogenesis in the striatum of the quinolinic acid lesion model of Huntington's disease. Neuroscience 127 (2004), 319–332.
    • (2004) Neuroscience , vol.127 , pp. 319-332
    • Tattersfield, A.S.1    Croon, R.J.2    Liu, Y.W.3    Kells, A.P.4    Faull, R.L.5    Connor, B.6
  • 34
    • 79959810596 scopus 로고    scopus 로고
    • Dopaminergic neuronal differentiation protocol for human mesenchymal stem cells
    • Trzaska, K.A., Rameshwar, P., Dopaminergic neuronal differentiation protocol for human mesenchymal stem cells. Methods Mol. Biol. 698 (2011), 295–303.
    • (2011) Methods Mol. Biol. , vol.698 , pp. 295-303
    • Trzaska, K.A.1    Rameshwar, P.2
  • 36
    • 84964330746 scopus 로고    scopus 로고
    • Regulation of neurogenesis by neurotrophins during adulthood: expected and unexpected roles
    • Vilar, M., Mira, H., Regulation of neurogenesis by neurotrophins during adulthood: expected and unexpected roles. Front Neurosci., 10, 2016, 26.
    • (2016) Front Neurosci. , vol.10 , pp. 26
    • Vilar, M.1    Mira, H.2
  • 37
    • 0031815611 scopus 로고    scopus 로고
    • Effects of severity of host striatal damage on the morphological development of intrastriatal transplants in a rodent model of Huntington's disease: implications for timing of surgical intervention
    • Watts, C., Dunnett, S.B., Effects of severity of host striatal damage on the morphological development of intrastriatal transplants in a rodent model of Huntington's disease: implications for timing of surgical intervention. J. Neurosurg. 89 (1998), 267–274.
    • (1998) J. Neurosurg. , vol.89 , pp. 267-274
    • Watts, C.1    Dunnett, S.B.2
  • 38
    • 68849083063 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in neurodegenerative diseases
    • Zuccato, C., Cattaneo, E., Brain-derived neurotrophic factor in neurodegenerative diseases. Nat. Rev. Neurol. 5 (2009), 311–322.
    • (2009) Nat. Rev. Neurol. , vol.5 , pp. 311-322
    • Zuccato, C.1    Cattaneo, E.2
  • 39
    • 41149120252 scopus 로고    scopus 로고
    • Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease
    • Zuccato, C., Marullo, M., Conforti, P., MacDonald, M.E., Tartari, M., Cattaneo, E., Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease. Brain Pathol. 18 (2008), 225–238.
    • (2008) Brain Pathol. , vol.18 , pp. 225-238
    • Zuccato, C.1    Marullo, M.2    Conforti, P.3    MacDonald, M.E.4    Tartari, M.5    Cattaneo, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.