An influenza A virus (H7N9) anti-neuraminidase monoclonal antibody with prophylactic and therapeutic activity in vivo

Antiviral Research

Volumn 135, Issue , 2016, Pages 48-55

  Wilson, Jason R ^a,b   Guo, Zhu ^a   Reber, Adrian ^a   Kamal, Ram P ^a,c   Music, Nedzad ^a,c   Gansebom, Shane ^a,b   Bai, Yaohui ^a   Levine, Min ^a   Carney, Paul ^a   Tzeng, Wen Pin ^a   Stevens, James ^a   York, Ian A ^a  

^a NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^b Carter Consulting Inc   (United States)

^c BATTELLE MEMORIAL INSTITUTE   (United States)

Author keywords

Antiviral; H7N9; Influenza; Monoclonal antibody; NA epitope; Neuraminidase

Indexed keywords

ANTIVIRUS AGENT; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 3C10-3; SIALIDASE INHIBITOR; UNCLASSIFIED DRUG; VIRUS SIALIDASE; EPITOPE; NA PROTEIN, INFLUENZA A VIRUS; SIALIDASE; VIRAL PROTEIN; VIRUS ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIVIRAL ACTIVITY; ANTIVIRAL RESISTANCE; ANTIVIRAL THERAPY; ARTICLE; CELL SPREADING; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; EMBRYO; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; EPITOPE MAPPING; FEMALE; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; INFECTION PREVENTION; INFLUENZA A; INFLUENZA A VIRUS (H7N9); LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; SYSTEMIC THERAPY; WEIGHT REDUCTION; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CHINA; ENZYMOLOGY; HUMAN; IMMUNOLOGY; INFLUENZA; INTRAVENOUS DRUG ADMINISTRATION; ORTHOMYXOVIRUS INFECTION; VIROLOGY; VIRUS REPLICATION;

ADMINISTRATION, INTRAVENOUS; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, VIRAL; CATALYTIC DOMAIN; CHINA; DRUG RESISTANCE, VIRAL; EPITOPE MAPPING; EPITOPES; HUMANS; INFLUENZA A VIRUS, H7N9 SUBTYPE; INFLUENZA, HUMAN; MICE; NEURAMINIDASE; ORTHOMYXOVIRIDAE INFECTIONS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84992154463     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2016.10.001     Document Type: Article

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