A monoclonal antibody targeting a highly conserved epitope in influenza B neuraminidase provides protection against drug resistant strains

Biochemical and Biophysical Research Communications

Volumn 441, Issue 1, 2013, Pages 226-229

  Doyle, Tracey M ^a,e   Li, Changgui ^b   Bucher, Doris J ^d   Hashem, Anwar M ^a,c,e   Van Domselaar, Gary ^f   Wang, Junzhi ^b   Farnsworth, Aaron ^a   She, Yi Min ^a   Cyr, Terry ^a   He, Runtao ^f   Brown, Earl G ^e   Hurt, Aeron C ^g   Li, Xuguang ^a,e  

^a HEALTH CANADA   (Canada)

^b NATIONAL INSTITUTES FOR FOOD AND DRUG CONTROL   (China)

^c Aziz University   (Saudi Arabia)

^d NEW YORK MEDICAL COLLEGE   (United States)

^e UNIVERSITY OF OTTAWA   (Canada)

^f PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^g WHO COLLABORATING CENTRE FOR REFERENCE AND RESEARCH ON INFLUENZA   (Australia)

Author keywords

Cross protection; Influenza B; Neuraminidase; Universal antibody; Vaccination

Indexed keywords

ANTIBODY; ANTIVIRUS AGENT; EPITOPE; INFLUENZA B NEURAMINIDASE; INFLUENZA VACCINE; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; VIRUS SIALIDASE; SIALIDASE; VIRUS ANTIBODY;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; IMMUNE RESPONSE; INFLUENZA B; INFLUENZA VIRUS B; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTECTION; VIRUS STRAIN; AMINO ACID SEQUENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; ANTIVIRAL RESISTANCE; CHEMICAL STRUCTURE; CHEMISTRY; DOG; DRUG EFFECTS; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOLOGY; INFLUENZA, HUMAN; MDCK CELL LINE; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; VIROLOGY;

CERCOPITHECINE HERPESVIRUS 1; INFLUENZA B VIRUS; ORTHOMYXOVIRIDAE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, VIRAL; CONSERVED SEQUENCE; DOGS; DRUG RESISTANCE, VIRAL; EPITOPES; HUMANS; INFLUENZA B VIRUS; INFLUENZA, HUMAN; MADIN DARBY CANINE KIDNEY CELLS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NEURAMINIDASE;

EID: 84887477456     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.10.041     Document Type: Article

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