메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; IRON;

EID: 84992111252     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep35514     Document Type: Article
Times cited : (141)

References (71)
  • 1
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder, E. H. et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261, 921-923 (1993).
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1
  • 2
    • 0028178047 scopus 로고
    • Apolipoprotein e epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: Analysis of the 19q13. 2 chromosomal region
    • Chartier-Harlin, M. C. et al. Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13. 2 chromosomal region. Hum. Mol. Genet. 3, 569-574 (1994).
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 569-574
    • Chartier-Harlin, M.C.1
  • 3
    • 77649314191 scopus 로고    scopus 로고
    • APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
    • Morris, J. C. et al. APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Ann. Neurol. 67, 122-131 (2010).
    • (2010) Ann. Neurol. , vol.67 , pp. 122-131
    • Morris, J.C.1
  • 4
    • 0027365822 scopus 로고
    • Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein e genotype in late-onset Alzheimer disease
    • Schmechel, D. E. et al. Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90, 9649-9653 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9649-9653
    • Schmechel, D.E.1
  • 5
    • 84940040128 scopus 로고    scopus 로고
    • Amyloid-11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials
    • WNL. 0000000000001877
    • Liu, E. et al. Amyloid-11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials. Neurology 85, WNL. 0000000000001877 (2015).
    • (2015) Neurology , vol.85
    • Liu, E.1
  • 7
    • 46749113799 scopus 로고    scopus 로고
    • Targeting-amyloid pathology in Alzheimer's disease with A immunotherapy
    • Nitsch, R. M., Hock, C. Targeting-amyloid pathology in Alzheimer's disease with A immunotherapy. Neurotherapeutics 5, 415-420 (2008).
    • (2008) Neurotherapeutics , vol.5 , pp. 415-420
    • Nitsch, R.M.1    Hock, C.2
  • 8
    • 66149084048 scopus 로고    scopus 로고
    • Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease
    • Reiman, E. M. et al. Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease. Proc. Natl. Acad. Sci. USA 106, 6820-6825 (2009).
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 6820-6825
    • Reiman, E.M.1
  • 9
    • 84902162274 scopus 로고    scopus 로고
    • Amyloid and APOE 4 interact to influence short-term decline in preclinical Alzheimer disease
    • Mormino, E. C. et al. Amyloid and APOE 4 interact to influence short-term decline in preclinical Alzheimer disease. Neurology 82, 1760-1767 (2014).
    • (2014) Neurology , vol.82 , pp. 1760-1767
    • Mormino, E.C.1
  • 10
    • 84930225631 scopus 로고    scopus 로고
    • Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE
    • Ayton, S. et al. Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE. Nat. Commun. 6, 6760 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 6760
    • Ayton, S.1
  • 11
    • 84936846544 scopus 로고    scopus 로고
    • Alzheimer disease: Iron-The missing link between ApoE and Alzheimer disease Nat
    • Wood, H. Alzheimer disease: Iron-the missing link between ApoE and Alzheimer disease Nat. Rev. Neurol. 11, 369 (2015).
    • (2015) Rev. Neurol. , vol.11 , pp. 369
    • Wood, H.1
  • 12
    • 84942549571 scopus 로고    scopus 로고
    • Quantifying brain iron deposition in patients with Parkinson's disease using quantitative susceptibility mapping, R2 and R2
    • Barbosa, J. H. O. et al. Quantifying brain iron deposition in patients with Parkinson's disease using quantitative susceptibility mapping, R2 and R2. Magn. Reson. Imaging 33, 559-565 (2015).
    • (2015) Magn. Reson. Imaging , vol.33 , pp. 559-565
    • Barbosa, J.H.O.1
  • 13
    • 84930975150 scopus 로고    scopus 로고
    • Usefulness of quantitative susceptibility mapping for the diagnosis of Parkinson disease
    • Murakami, Y. et al. Usefulness of Quantitative Susceptibility Mapping for the Diagnosis of Parkinson Disease. Am. J. Neuroradiol. 36, 1102-1108 (2015).
    • (2015) Am. J. Neuroradiol. , vol.36 , pp. 1102-1108
    • Murakami, Y.1
  • 14
    • 33846043512 scopus 로고    scopus 로고
    • Correlation of proton transverse relaxation rates (R2) with iron concentrations in postmortem brain tissue from Alzheimer's disease patients
    • House, M. J. et al. Correlation of proton transverse relaxation rates (R2) with iron concentrations in postmortem brain tissue from Alzheimer's disease patients. Magn. Reson. Med. 57, 172-180 (2007).
    • (2007) Magn. Reson. Med. , vol.57 , pp. 172-180
    • House, M.J.1
  • 15
    • 0026513756 scopus 로고
    • A histochemical study of iron, transferrin, ferritin in Alzheimer's diseased brains
    • Connor, J. R., Menzies, S. L., St Martin, S. M., Mufson, E. J. A histochemical study of iron, transferrin, ferritin in Alzheimer's diseased brains. J. Neurosci. Res. 31, 75-83 (1992).
    • (1992) J. Neurosci. Res. , vol.31 , pp. 75-83
    • Connor, J.R.1    Menzies, S.L.2    St Martin, S.M.3    Mufson, E.J.4
  • 16
    • 84872562074 scopus 로고    scopus 로고
    • The metal theory of Alzheimer's disease
    • Bush, A. I. The metal theory of Alzheimer's disease. J. Alzheimers. Dis. 33 Suppl 1, S277-S281 (2013).
    • (2013) J. Alzheimers. Dis. , vol.33 , pp. S277-S281
    • Bush, A.I.1
  • 17
    • 0005652488 scopus 로고    scopus 로고
    • MRI evaluation of basal ganglia ferritin iron and neurotoxicity in Alzheimer's and Huntingon's disease
    • Bartzokis, G., Tishler, T. a. MRI evaluation of basal ganglia ferritin iron and neurotoxicity in Alzheimer's and Huntingon's disease. Cell. Mol. Biol. 46, 821-833 (2000).
    • (2000) Cell. Mol. Biol. , vol.46 , pp. 821-833
    • Bartzokis, G.1    Tishler, T.A.2
  • 18
    • 84896734166 scopus 로고    scopus 로고
    • In vivo quantitative susceptibility mapping (QSM) in Alzheimer's disease
    • Acosta-Cabronero, J. et al. In vivo quantitative susceptibility mapping (QSM) in Alzheimer's disease. PLoS One 8, e81093 (2013).
    • (2013) PLoS One , vol.8 , pp. e81093
    • Acosta-Cabronero, J.1
  • 19
    • 77956647381 scopus 로고    scopus 로고
    • Iron-Export ferroxidase activity of-amyloid precursor protein is inhibited by zinc in Alzheimer's disease
    • Duce, J. a. et al. Iron-Export Ferroxidase Activity of-Amyloid Precursor Protein is Inhibited by Zinc in Alzheimer's Disease. Cell 142, 857-867 (2010).
    • (2010) Cell , vol.142 , pp. 857-867
    • Duce, J.A.1
  • 20
    • 79952996094 scopus 로고    scopus 로고
    • Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation
    • Liu, B. et al. Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation. J. Biol. Chem. 286, 4248-4256 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 4248-4256
    • Liu, B.1
  • 21
    • 59649091470 scopus 로고    scopus 로고
    • Iron A pathological mediator of Alzheimer disease
    • Rolston, R. K. et al. Iron A pathological mediator of Alzheimer disease Agro Food Ind. Hi. Tech. 19, 33-36 (2008).
    • (2008) Agro Food Ind. Hi. Tech. , vol.19 , pp. 33-36
    • Rolston, R.K.1
  • 22
    • 84940467351 scopus 로고    scopus 로고
    • Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease
    • Zeineh, M. M. et al. Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease. Neurobiol. Aging, doi: 10. 1016/j. neurobiolaging. 2015. 05. 022 (2015).
    • (2015) Neurobiol. Aging
    • Zeineh, M.M.1
  • 23
    • 84868217296 scopus 로고    scopus 로고
    • Toward in vivo histology: A comparison of quantitative susceptibility mapping (QSM) with magnitude-, phase-, R2-imaging at ultra-high magnetic field strength
    • Deistung, A. et al. Toward in vivo histology: A comparison of quantitative susceptibility mapping (QSM) with magnitude-, phase-, R2-imaging at ultra-high magnetic field strength. Neuroimage 65, 299-314 (2013).
    • (2013) Neuroimage , vol.65 , pp. 299-314
    • Deistung, A.1
  • 24
    • 84879757543 scopus 로고    scopus 로고
    • Human brain atlas for automated region of interest selection in quantitative susceptibility mapping: Application to determine iron content in deep gray matter structures
    • Lim, I. A. L. et al. Human brain atlas for automated region of interest selection in quantitative susceptibility mapping: Application to determine iron content in deep gray matter structures. Neuroimage 82, 449-469 (2013).
    • (2013) Neuroimage , vol.82 , pp. 449-469
    • Lim, I.A.L.1
  • 25
    • 84863747371 scopus 로고    scopus 로고
    • Quantitative susceptibility mapping for investigating subtle susceptibility variations in the human brain
    • Schweser, F., Sommer, K., Deistung, A., Reichenbach, J. R. Quantitative susceptibility mapping for investigating subtle susceptibility variations in the human brain. Neuroimage 62, 2083-2100 (2012).
    • (2012) Neuroimage , vol.62 , pp. 2083-2100
    • Schweser, F.1    Sommer, K.2    Deistung, A.3    Reichenbach, J.R.4
  • 26
    • 79952665743 scopus 로고    scopus 로고
    • Quantitative susceptibility mapping of human brain reflects spatial variation in tissue composition
    • Li, W., Wu, B., Liu, C. Quantitative susceptibility mapping of human brain reflects spatial variation in tissue composition. Neuroimage 55, 1645-1656 (2011).
    • (2011) Neuroimage , vol.55 , pp. 1645-1656
    • Li, W.1    Wu, B.2    Liu, C.3
  • 27
    • 73349121926 scopus 로고    scopus 로고
    • Quantitative susceptibility map reconstruction from MR phase data using Bayesian regularization: Validation and application to brain imaging
    • De Rochefort, L. et al. Quantitative susceptibility map reconstruction from MR phase data using bayesian regularization: Validation and application to brain imaging. Magn. Reson. Med. 63, 194-206 (2010).
    • (2010) Magn. Reson. Med. , vol.63 , pp. 194-206
    • De Rochefort, L.1
  • 28
    • 78650953898 scopus 로고    scopus 로고
    • Quantitative imaging of intrinsic magnetic tissue properties using MRI signal phase: An approach to in vivo brain iron metabolism
    • Schweser, F., Deistung, A., Lehr, B. W., Reichenbach, J. R. Quantitative imaging of intrinsic magnetic tissue properties using MRI signal phase: An approach to in vivo brain iron metabolism Neuroimage 54, 2789-2807 (2011).
    • (2011) Neuroimage , vol.54 , pp. 2789-2807
    • Schweser, F.1    Deistung, A.2    Lehr, B.W.3    Reichenbach, J.R.4
  • 29
    • 84863522265 scopus 로고    scopus 로고
    • Quantitative susceptibility mapping (QSM) as a means to measure brain iron A post mortem validation study
    • Langkammer, C. et al. Quantitative susceptibility mapping (QSM) as a means to measure brain iron A post mortem validation study. Neuroimage 62, 1593-1599 (2012).
    • (2012) Neuroimage , vol.62 , pp. 1593-1599
    • Langkammer, C.1
  • 30
    • 84899473435 scopus 로고    scopus 로고
    • Amyloid deposition is linked to aberrant entorhinal activity among cognitively normal older adults
    • Huijbers, W. et al. Amyloid deposition is linked to aberrant entorhinal activity among cognitively normal older adults. J. Neurosci. 34, 5200-5210 (2014).
    • (2014) J. Neurosci. , vol.34 , pp. 5200-5210
    • Huijbers, W.1
  • 31
    • 67650875899 scopus 로고    scopus 로고
    • Amyloid deposition is associated with impaired default network function in older persons without dementia
    • Sperling, R. A. et al. Amyloid Deposition Is Associated with Impaired Default Network Function in Older Persons without Dementia. Neuron 63, 178-188 (2009).
    • (2009) Neuron , vol.63 , pp. 178-188
    • Sperling, R.A.1
  • 32
    • 84882259266 scopus 로고    scopus 로고
    • Functional connectivity in Alzheimer's disease: Measurement and meaning
    • Johnson, K. a., Sperling, R. a., Sepulcre, J. Functional connectivity in Alzheimer's disease: Measurement and meaning. Biol. Psychiatry 74, 318-319 (2013).
    • (2013) Biol. Psychiatry , vol.74 , pp. 318-319
    • Johnson, K.A.1    Sperling, R.A.2    Sepulcre, J.3
  • 33
    • 33747048954 scopus 로고    scopus 로고
    • [11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease
    • Mintun, M. a. et al. [11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease. Neurology 67, 446-452 (2006).
    • (2006) Neurology , vol.67 , pp. 446-452
    • Mintun, M.A.1
  • 34
    • 23944444806 scopus 로고    scopus 로고
    • Molecular structural, functional characterization of Alzheimer's disease: Evidence for a relationship between default activity, amyloid, memory
    • Buckner, R. L. Molecular, Structural, Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, Memory. J. Neurosci. 25, 7709-7717 (2005).
    • (2005) J. Neurosci. , vol.25 , pp. 7709-7717
    • Buckner, R.L.1
  • 35
    • 76849104065 scopus 로고    scopus 로고
    • Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly
    • Sheline, Y. I. et al. Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly. Biol. Psychiatry. 67, 584-587 (2010).
    • (2010) Biol. Psychiatry. , vol.67 , pp. 584-587
    • Sheline, Y.I.1
  • 36
    • 77952496309 scopus 로고    scopus 로고
    • Functional alterations in memory networks in early Alzheimer's disease
    • Sperling, R. A. et al. Functional alterations in memory networks in early Alzheimer's disease. Neuromolecular Med. 12, 27-43 (2010).
    • (2010) Neuromolecular Med. , vol.12 , pp. 27-43
    • Sperling, R.A.1
  • 37
    • 84920603179 scopus 로고    scopus 로고
    • Relationships between default-mode network connectivity, medial temporal lobe structure, age-related memory deficits
    • Ward, A. M. et al. Relationships between default-mode network connectivity, medial temporal lobe structure, age-related memory deficits. Neurobiol. Aging 36, 265-272 (2014).
    • (2014) Neurobiol. Aging , vol.36 , pp. 265-272
    • Ward, A.M.1
  • 38
    • 84911399894 scopus 로고    scopus 로고
    • Whole-brain three-dimensional T2-weighted BOLD functional magnetic resonance imaging at 7 Tesla
    • Hua, J., Qin, Q., van Zijl, P. C. M., Pekar, J. J., Jones, C. K. Whole-brain three-dimensional T2-weighted BOLD functional magnetic resonance imaging at 7 Tesla. Magn. Reson. Med. 72, 1530-1540 (2014).
    • (2014) Magn. Reson. Med. , vol.72 , pp. 1530-1540
    • Hua, J.1    Qin, Q.2    Van Zijl, P.C.M.3    Pekar, J.J.4    Jones, C.K.5
  • 39
    • 79956098248 scopus 로고    scopus 로고
    • Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • Sperling, R. A. et al. Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's Dement. 7, 280-292 (2011).
    • (2011) Alzheimer's Dement. , vol.7 , pp. 280-292
    • Sperling, R.A.1
  • 40
    • 10744232413 scopus 로고    scopus 로고
    • Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
    • Klunk, W. E. et al. Imaging Brain Amyloid in Alzheimer's Disease with Pittsburgh Compound-B. Ann. Neurol. 55, 306-319 (2004).
    • (2004) Ann. Neurol. , vol.55 , pp. 306-319
    • Klunk, W.E.1
  • 41
    • 13444291132 scopus 로고    scopus 로고
    • Efficient radiosynthesis of carbon-11 labelled uncharged Thioflavin T derivatives using [11C]methyl triflate for-amyloid imaging in Alzheimer's Disease with PET
    • Solbach, C., Uebele, M., Reischl, G., MacHulla, H. J. Efficient radiosynthesis of carbon-11 labelled uncharged Thioflavin T derivatives using [11C]methyl triflate for-amyloid imaging in Alzheimer's Disease with PET. Appl. Radiat. Isot. 62, 591-595 (2005).
    • (2005) Appl. Radiat. Isot. , vol.62 , pp. 591-595
    • Solbach, C.1    Uebele, M.2    Reischl, G.3    MacHulla, H.J.4
  • 42
    • 0032988610 scopus 로고    scopus 로고
    • Mild cognitive impairment: Clinical characterization and outcome
    • Petersen, R. C. et al. Mild cognitive impairment: clinical characterization and outcome. Arch. Neurol. 56, 303-308 (1999).
    • (1999) Arch. Neurol. , vol.56 , pp. 303-308
    • Petersen, R.C.1
  • 43
    • 79956142378 scopus 로고    scopus 로고
    • The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • McKhann, G. M. et al. The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's Dement. 7, 263-269 (2011).
    • (2011) Alzheimer's Dement. , vol.7 , pp. 263-269
    • McKhann, G.M.1
  • 44
    • 0016823810 scopus 로고
    • 'Mini-mental state' A practical method for grading the cognitive state of patients for the clinician
    • Folstein, M. F., Folstein, S. E., McHugh, P. R. 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12, 189-198 (1975).
    • (1975) J. Psychiatr. Res. , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 45
    • 18944374033 scopus 로고    scopus 로고
    • The Montreal Cognitive Assessment, MoCA: A brief screening tool for mild cognitive impairment
    • Nasreddine, Z. S. et al. The Montreal Cognitive Assessment, MoCA: A brief screening tool for mild cognitive impairment. J. Am. Geriatr. Soc. 53, 695-699 (2005).
    • (2005) J. Am. Geriatr. Soc. , vol.53 , pp. 695-699
    • Nasreddine, Z.S.1
  • 46
    • 0025320882 scopus 로고
    • The Verbal Learning and Retention Test. A useful and differentiated tool in evaluating verbal memory performance
    • Zurich, Switz 1985
    • Helmstaedter, C., Durwen, H. F. [The Verbal Learning and Retention Test. A useful and differentiated tool in evaluating verbal memory performance]. Schweizer Arch. fur Neurol. und Psychiatr. (Zurich, Switz. 1985) 141, 21-30 (1990).
    • (1990) Schweizer Arch. fur Neurol. und Psychiatr. , vol.141 , pp. 21-30
    • Helmstaedter, C.1    Durwen, H.F.2
  • 47
    • 0026375223 scopus 로고
    • The Wechsler Memory Scale-Revised: Psychometric characteristics and clinical application
    • Elwood, R. W. The Wechsler Memory Scale-Revised: psychometric characteristics and clinical application. Neuropsychol. Rev. 2, 179-201 (1991).
    • (1991) Neuropsychol. Rev. , vol.2 , pp. 179-201
    • Elwood, R.W.1
  • 48
    • 0024376693 scopus 로고
    • Revised administration and scoring procedures for the Boston Naming test and norms for non-brain-damaged adults
    • Nicholas, L. E., Brookshire, R. H., Maclennan, D. L. Schumacher, J. G., Porrazzo, S. a. Revised administration and scoring procedures for the Boston Naming test and norms for non-brain-damaged adults. Aphasiology 3, 569-580 (1989).
    • (1989) Aphasiology , vol.3 , pp. 569-580
    • Nicholas, L.E.1    Brookshire, R.H.2    Maclennan, D.L.3    Schumacher, J.G.4    Porrazzo, S.A.5
  • 49
    • 1542328836 scopus 로고    scopus 로고
    • Trail making test A and B: Normative data stratified by age and education
    • Tombaugh, T. N. Trail Making Test A and B: Normative data stratified by age and education. Arch. Clin. Neuropsychol. 19, 203-214 (2004).
    • (2004) Arch. Clin. Neuropsychol. , vol.19 , pp. 203-214
    • Tombaugh, T.N.1
  • 51
    • 77956384880 scopus 로고    scopus 로고
    • 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment a phase 2 trial
    • Vandenberghe, R. et al. 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment a phase 2 trial. Ann. Neurol. 68, 319-329 (2010).
    • (2010) Ann. Neurol. , vol.68 , pp. 319-329
    • Vandenberghe, R.1
  • 52
    • 80054108969 scopus 로고    scopus 로고
    • Fast and tissue-optimized mapping of magnetic susceptibility and T2∗with multiecho and multi-shot spirals
    • Wu, B., Li, W., Avram, A. V., Gho, S. M., Liu, C. Fast and tissue-optimized mapping of magnetic susceptibility and T2∗with multiecho and multi-shot spirals. Neuroimage 59, 297-305 (2012).
    • (2012) Neuroimage , vol.59 , pp. 297-305
    • Wu, B.1    Li, W.2    Avram, A.V.3    Gho, S.M.4    Liu, C.5
  • 53
    • 0039943513 scopus 로고
    • LSQR: An algorithm for sparse linear equations and sparse least squares
    • Paige, C. C., Saunders, M. a. LSQR: An Algorithm for Sparse Linear Equations and Sparse Least Squares. ACM Trans. Math. Softw. 8, 43-71 (1982).
    • (1982) ACM Trans. Math. Softw. , vol.8 , pp. 43-71
    • Paige, C.C.1    Saunders, M.A.2
  • 54
    • 84879131763 scopus 로고    scopus 로고
    • Bayesian parameter estimation and segmentation in the multi-atlas random orbit model
    • Tang, X. et al. Bayesian Parameter Estimation and Segmentation in the Multi-Atlas Random Orbit Model. PLoS One 8, e65591 (2013).
    • (2013) PLoS One , vol.8 , pp. e65591
    • Tang, X.1
  • 55
    • 84904724125 scopus 로고    scopus 로고
    • Tools for multiple granularity analysis of brain MRI data for individualized image analysis
    • Djamanakova, A. et al. Tools for multiple granularity analysis of brain MRI data for individualized image analysis. Neuroimage 101, 168-176 (2014).
    • (2014) Neuroimage , vol.101 , pp. 168-176
    • Djamanakova, A.1
  • 56
    • 85016018630 scopus 로고    scopus 로고
    • A functional connectivity toolbox for correlated and anticorrelated brain networks
    • Whitfield-Gabrieli, S., Nieto-Castanon, A. A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks. Brain Connect. 2, 125-141 (2012).
    • (2012) Brain Connect. , vol.2 , pp. 125-141
    • Whitfield-Gabrieli, S.1    Nieto-Castanon, A.2
  • 59
    • 67849121862 scopus 로고    scopus 로고
    • Serial susceptibility weighted MRI measures brain iron and microbleeds in dementia
    • Kirsch, W. et al. Serial susceptibility weighted MRI measures brain iron and microbleeds in dementia. J. Alzheimer's Dis. 17, 599-609 (2009).
    • (2009) J. Alzheimer's Dis. , vol.17 , pp. 599-609
    • Kirsch, W.1
  • 60
    • 84964600620 scopus 로고    scopus 로고
    • Is amyloid-harmful to the brain Insights from human imaging studies
    • Jagust, W. Is amyloid-harmful to the brain Insights from human imaging studies. Brain 139, 23-30 (2016).
    • (2016) Brain , vol.139 , pp. 23-30
    • Jagust, W.1
  • 61
    • 84912064760 scopus 로고    scopus 로고
    • Synergistic effect of-amyloid and neurodegeneration on cognitive decline in clinically normal individuals
    • Mormino, E. C. et al. Synergistic effect of-amyloid and neurodegeneration on cognitive decline in clinically normal individuals. JAMA Neurol. 71, 1379-1385 (2014).
    • (2014) JAMA Neurol. , vol.71 , pp. 1379-1385
    • Mormino, E.C.1
  • 62
    • 84856974910 scopus 로고    scopus 로고
    • Functional connectivity tracks clinical deterioration in Alzheimer's disease
    • Damoiseaux, J. S., Prater, K. E., Miller, B. L., Greicius, M. D. Functional connectivity tracks clinical deterioration in Alzheimer's disease. Neurobiol. Aging 33, 828. e19-30 (2012).
    • (2012) Neurobiol. Aging , vol.33 , pp. 828e19-828e30
    • Damoiseaux, J.S.1    Prater, K.E.2    Miller, B.L.3    Greicius, M.D.4
  • 63
    • 84861870800 scopus 로고    scopus 로고
    • Resting state fMRI in Alzheimer's disease: Beyond the default mode network
    • Agosta, F. et al. Resting state fMRI in Alzheimer's disease: beyond the default mode network. Neurobiol. Aging 33, 1564-1578 (2012).
    • (2012) Neurobiol. Aging , vol.33 , pp. 1564-1578
    • Agosta, F.1
  • 64
    • 60849136325 scopus 로고    scopus 로고
    • Cortical hubs revealed by intrinsic functional connectivity: Mapping, assessment of stability, relation to Alzheimer's disease
    • Buckner, R. L. et al. Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, relation to Alzheimer's disease. J. Neurosci. 29, 1860-1873 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 1860-1873
    • Buckner, R.L.1
  • 65
    • 84877326649 scopus 로고    scopus 로고
    • ApoE influences amyloid-(A ) clearance despite minimal apoE/A association in physiological conditions
    • Verghese, P. B. et al. ApoE influences amyloid-(A ) clearance despite minimal apoE/A association in physiological conditions. Proc. Natl. Acad. Sci. USA 110, E1807-E1816 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. E1807-E1816
    • Verghese, P.B.1
  • 66
    • 18344414746 scopus 로고    scopus 로고
    • The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
    • Huang, X. et al. The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry 38, 7609-7616 (1999).
    • (1999) Biochemistry , vol.38 , pp. 7609-7616
    • Huang, X.1
  • 67
    • 84897954445 scopus 로고    scopus 로고
    • Microglial dysfunction in brain aging and Alzheimer's disease
    • Mosher, K. I., Wyss-Coray, T. Microglial dysfunction in brain aging and Alzheimer's disease. Biochem. Pharmacol. 88, 594-604 (2014).
    • (2014) Biochem. Pharmacol. , vol.88 , pp. 594-604
    • Mosher, K.I.1    Wyss-Coray, T.2
  • 68
    • 79955467024 scopus 로고    scopus 로고
    • High-field (9. 4T) MRI of brain dysmyelination by quantitative mapping of magnetic susceptibility
    • Liu, C., Li, W., Johnson, G. A., Wu, B. High-field (9. 4T) MRI of brain dysmyelination by quantitative mapping of magnetic susceptibility. Neuroimage 56, 930-938 (2011).
    • (2011) Neuroimage , vol.56 , pp. 930-938
    • Liu, C.1    Li, W.2    Johnson, G.A.3    Wu, B.4
  • 69
    • 78149492502 scopus 로고    scopus 로고
    • Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy
    • Dierksen, G. A. et al. Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy. Ann. Neurol. 68, 545-548 (2010).
    • (2010) Ann. Neurol. , vol.68 , pp. 545-548
    • Dierksen, G.A.1
  • 71
    • 0025726462 scopus 로고
    • Intramuscular desferrioxamine in patients with Alzheimer's disease
    • (London, England)
    • Crapper McLachlan, D. R. et al. Intramuscular desferrioxamine in patients with Alzheimer's disease. Lancet (London, England) 337, 1304-1308 (1991).
    • (1991) Lancet , vol.337 , pp. 1304-1308
    • Crapper McLachlan, D.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.