Vaccinating with conserved Escherichia coli antigens does not alter the mouse intestinal microbiome

BMC Research Notes

Volumn 9, Issue 1, 2016, Pages

  Hays, Michael P ^a   Ericsson, Aaron C ^b   Yang, Yang ^a   Hardwidge, Philip R ^a  

^a KANSAS STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; ESCHERICHIA COLI VACCINE; IMMUNOGLOBULIN G;

AMINO ACID SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; CONSERVED SEQUENCE; ENTEROTOXIGENIC ESCHERICHIA COLI; FEMALE; IMMUNOLOGY; INTESTINE FLORA; MOUSE; PRINCIPAL COMPONENT ANALYSIS; VACCINATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, BACTERIAL; CONSERVED SEQUENCE; ENTEROTOXIGENIC ESCHERICHIA COLI; ESCHERICHIA COLI VACCINES; FEMALE; GASTROINTESTINAL MICROBIOME; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; PRINCIPAL COMPONENT ANALYSIS; VACCINATION;

EID: 84992026532     PISSN: None     EISSN: 17560500     Source Type: Journal    
DOI: 10.1186/s13104-016-2208-y     Document Type: Article

References (27)

1. Fleckenstein JM, Hardwidge PR, Munson GP, Rasko DA, Sommerfelt H, Steinsland H. Molecular mechanisms of enterotoxigenic Escherichia coli infection. Microbes Infect. 2010;12(2):89-98. doi: 10.1016/j.micinf.2009.10.002.
2. Knutton S, Lloyd DR, Candy DC, McNeish AS. Adhesion of enterotoxigenic Escherichia coli to human small intestinal enterocytes. Infect Immun. 1985;48(3):824-31.
3. Fleckenstein J, Sheikh A, Qadri F. Novel antigens for enterotoxigenic Escherichia coli vaccines. Exp Rev Vacc. 2014;13(5):631-9.
4. Kumar A, Hays M, Lim F, Foster LJ, Zhou M, Zhu G, et al. Protective enterotoxigenic Escherichia coli antigens in a murine intranasal challenge model. PLoS Negl Trop Dis. 2015;9(8):e0003924.
5. Sklar JG, Wu T, Kahne D, Silhavy TJ. Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in Escherichia coli. Genes Dev. 2007;21(19):2473-84.
6. Roy K, Bartels S, Qadri F, Fleckenstein JM. Enterotoxigenic Escherichia coli elicits immune responses to multiple surface proteins. Infect Immun. 2010;78(7):3027-35.
7. Kumar GB, Black PN. Linker mutagenesis of a bacterial fatty acid transport protein. Identification of domains with functional importance. J Biol Chem. 1991;266(2):1348-53.
8. Turbyfill KR, Hartman AB, Oaks EV. Isolation and characterization of a Shigella flexneri invasin complex subunit vaccine. Infect Immun. 2000;68(12):6624-32.
9. van de Verg LL, Mallett CP, Collins HH, Larsen T, Hammack C, Hale TL. Antibody and cytokine responses in a mouse pulmonary model of Shigella flexneri serotype 2a infection. Infect Immun. 1995;63(5):1947-54.
10. Roy K, Hamilton D, Allen KP, Randolph MP, Fleckenstein JM. The EtpA exoprotein of enterotoxigenic Escherichia coli promotes intestinal colonization and is a protective antigen in an experimental model of murine infection. Infect Immun. 2008;76(5):2106-12.
11. Zhang Q, Pan Y, Yan R, Zeng B, Wang H, Zhang X, et al. Commensal bacteria direct selective cargo sorting to promote symbiosis. Nat Immunol. 2015;16(9):918-26.
12. Nakaya HI, Bruna-Romero O. Is the gut microbiome key to modulating vaccine efficacy? Exp Rev Vacc. 2015;14(6):777-9.
13. Ang L, Arboleya S, Lihua G, Chuihui Y, Nan Q, Suarez M, et al. The establishment of the infant intestinal microbiome is not affected by rotavirus vaccination. Sci Rep. 2014;4:7417.
14. Seekatz AM, Panda A, Rasko DA, Toapanta FR, Eloe-Fadrosh EA, Khan AQ, et al. Differential response of the cynomolgus macaque gut microbiota to Shigella infection. PloS ONE. 2013;8(6):e64212.
15. Eloe-Fadrosh EA, McArthur MA, Seekatz AM, Drabek EF, Rasko DA, Sztein MB, et al. Impact of oral typhoid vaccination on the human gut microbiota and correlations with S. Typhi-specific immunological responses. PloS ONE. 2013;8(4):e62026.
16. Hart ML, Meyer A, Johnson PJ, Ericsson AC. Comparative evaluation of DNA extraction methods from feces of multiple host species for downstream next-generation sequencing. PloS ONE. 2015;10(11):e0143334.
17. Caporaso JG, Lauber CL, Walters WA, Berg-Lyons D, Lozupone CA, Turnbaugh PJ, et al. Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample. Proc Natl Acad Sci USA. 2011;15(108 Suppl 1):4516-22.
18. Magoc T, Salzberg SL. FLASH: fast length adjustment of short reads to improve genome assemblies. Bioinformatics. 2011;27(21):2957-63.
19. Kuczynski J, Stombaugh J, Walters WA, Gonzalez A, Caporaso JG, Knight R. Using QIIME to analyze 16S rRNA gene sequences from microbial communities. Curr Protoc Bioinformatics. 2011;Chapter 10:Unit 10.7. doi: 10.1002/0471250953.bi1007s36.
20. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucl Acids Res. 1997;25(17):3389-402.
21. DeSantis TZ, Hugenholtz P, Larsen N, Rojas M, Brodie EL, Keller K, et al. Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB. Appl Environ Microbiol. 2006;72(7):5069-72.
22. Donnenberg MS, Yu J, Kaper JB. A second chromosomal gene necessary for intimate attachment of enteropathogenic Escherichia coli to epithelial cells. J Bacteriol. 1993;175(15):4670-80.
23. Tacket CO, Sztein MB, Losonsky G, Abe A, Finlay BB, McNamara BP, et al. Role of EspB in experimental human enteropathogenic Escherichia coli infection. Infect Immun. 2000;68(6):3689-95.
24. Conway T, Cohen PS. Commensal and pathogenic Escherichia coli metabolism in the gut. Microbiol Spectr. 2015;3(3). doi: 10.1128/microbiolspec.MBP-0006-2014.
25. Grozdanov L, Raasch C, Schulze J, Sonnenborn U, Gottschalk G, Hacker J, et al. Analysis of the genome structure of the nonpathogenic probiotic Escherichia coli strain Nissle 1917. J Bacteriol. 2004;186(16):5432-41.
26. Martin R, Miquel S, Ulmer J, Kechaou N, Langella P, Bermudez-Humaran LG. Role of commensal and probiotic bacteria in human health: a focus on inflammatory bowel disease. Microb Cell Fact. 2013;12:71.
27. Ericsson AC, Davis JW, Spollen W, Bivens N, Givan S, Hagan CE, et al. Effects of vendor and genetic background on the composition of the fecal microbiota of inbred mice. PloS ONE. 2015;10(2):e0116704.