Rationale and design of the Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry: A comprehensive exploration of plaque progression and its impact on clinical outcomes from a multicenter serial coronary computed tomographic angiography study

American Heart Journal

Volumn 182, Issue , 2016, Pages 72-79

  Lee, Sang Eun ^a   Chang, Hyuk Jae ^a   Rizvi, Asim ^b   Hadamitzky, Martin ^c   Kim, Yong Jin ^d   Conte, Edoardo ^e   Andreini, Daniele ^e   Pontone, Gianluca ^e   Volpato, Valentina ^e   Budoff, Matthew J ^f   Gottlieb, Ilan ^g   Lee, Byoung Kwon ^h   Chun, Eun Ju ⁱ   Cademartiri, Filippo ^j   Maffei, Erica ^j   Marques, Hugo ^k   Leipsic, Jonathon A ^l   Shin, Sanghoon ^m   Choi, Jung Hyun ⁿ   Chung, Namsik ^a   Min, James K ^b   more..

^a Yonsei University College of Medicine   (South Korea)

^b NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^c UNIVERSITY OF MUNICH   (Germany)

^d Seoul National University Hospital   (South Korea)

^e CENTRO CARDIOLOGICO MONZINO   (Italy)

^f HARBOR UCLA MEDICAL CENTER   (United States)

^g Casa de Saude São Jose ^*  (Brazil)

^h Yonsei University College of Medicine   (South Korea)

ⁱ Seoul National University Bundang Hospital   (South Korea)

^j MONTREAL HEART INSTITUTE   (Canada)

^k HOSPITAL DA LUZ   (Portugal)

^l UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^m National Health Insurance Corporation   (South Korea)

ⁿ Pusan National University School of Medicine   (South Korea)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ATHEROSCLEROTIC PLAQUE; CLINICAL DATA REPOSITORY; CLINICAL OUTCOME; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CORONARY ARTERY ATHEROSCLEROSIS; DISEASE COURSE; DISEASE REGISTRY; FEMALE; FOLLOW UP; GEOGRAPHIC DISTRIBUTION; HEART DEATH; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HOSPITALIZATION; HUMAN; MALE; MULTICENTER STUDY; OBSERVATIONAL STUDY; PATIENT SELECTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SAMPLE SIZE; STUDY DESIGN; UNSTABLE ANGINA PECTORIS; AGED; CLINICAL TRIAL; COMPLICATION; CORONARY ARTERY DISEASE; CORONARY BLOOD VESSEL; DIAGNOSTIC IMAGING; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PLAQUE, ATHEROSCLEROTIC; PREDICTIVE VALUE; PROCEDURES; PROGNOSIS; REGISTER; RISK ASSESSMENT;

ADULT; AGED; COMPUTED TOMOGRAPHY ANGIOGRAPHY; CORONARY ARTERY DISEASE; CORONARY VESSELS; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; PLAQUE, ATHEROSCLEROTIC; PREDICTIVE VALUE OF TESTS; PROGNOSIS; REGISTRIES; RISK ASSESSMENT;

EID: 84991735344     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2016.09.003     Document Type: Article

References (55)

1. 1. Naghavi, M., Wang, H., Lozano, R., et al. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 385 (2015), 117–171.
2. 2. Sakakura, K., Nakano, M., Otsuka, F., et al. Pathophysiology of atherosclerosis plaque progression. Heart Lung Circ 22 (2013), 399–411.
3. 3. Smith, S.C. Jr., Grundy, S.M., 2013 ACC/AHA guideline recommends fixed-dose strategies instead of targeted goals to lower blood cholesterol. J Am Coll Cardiol 64 (2014), 601–612.
4. 4. Vos, J., De Feyter, P., Kingma, J., et al. Evolution of coronary atherosclerosis in patients with mild coronary artery disease studied by serial quantitative coronary angiography at 2 and 4 years follow-up. Eur Heart J 18 (1997), 1081–1089.
5. 5. Jukema, J.W., Bruschke, A.V., van Boven, A.J., et al. Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels: the Regression Growth Evaluation Statin Study (REGRESS). Circulation 91 (1995), 2528–2540.
6. 6. Nicholls, S.J., Tuzcu, E.M., Wolski, K., et al. Lowering the triglyceride/high-density lipoprotein cholesterol ratio is associated with the beneficial impact of pioglitazone on progression of coronary atherosclerosis in diabetic patients: insights from the PERISCOPE (Pioglitazone Effect on Regression of Intravascular Sonographic Coronary Obstruction Prospective Evaluation) study. J Am Coll Cardiol 57 (2011), 153–159.
7. 7. Nicholls, S.J., Tuzcu, E.M., Brennan, D.M., et al. Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation). Circulation 118 (2008), 2506–2514.
8. 8. Nissen, S.E., Tuzcu, E.M., Brewer, H.B., et al. Effect of ACAT inhibition on the progression of coronary atherosclerosis. N Engl J Med 354 (2006), 1253–1263.
9. 9. Fihn, S.D., Gardin, J.M., Abrams, J., et al. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol 60 (2012), e44–e164.
10. 10. Task Force, M., Montalescot, G., Sechtem, U., et al. 2013 ESC guidelines on the management of stable coronary artery disease: the task force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J 34 (2013), 2949–3003.
11. 11. Nicholls, S.J., Tuzcu, E.M., Sipahi, I., et al. Statins, high-density lipoprotein cholesterol, and regression of coronary atherosclerosis. JAMA 297 (2007), 499–508.
12. 12. Dedic, A., Kurata, A., Lubbers, M., et al. Prognostic implications of non-culprit plaques in acute coronary syndrome: non-invasive assessment with coronary CT angiography. Eur Heart J Cardiovasc Imaging 15 (2014), 1231–1237.
13. 13. McPherson, J.A., Maehara, A., Weisz, G., et al. Residual plaque burden in patients with acute coronary syndromes after successful percutaneous coronary intervention. J Am Coll Cardiol Img 5 (2012), S76–S85.
14. 14. Stone, G.W., Maehara, A., Lansky, A.J., et al. A prospective natural-history study of coronary atherosclerosis. N Engl J Med 364 (2011), 226–235.
15. 15. Berry, C., L'Allier, P.L., Grégoire, J., et al. Comparison of intravascular ultrasound and quantitative coronary angiography for the assessment of coronary artery disease progression. Circulation 115 (2007), 1851–1857.
16. 16. Ornish, D., Scherwitz, L.W., Billings, J.H., et al. Intensive lifestyle changes for reversal of coronary heart disease. JAMA 280 (1998), 2001–2007.
17. 17. Brown, B.G., Zhao, X.-Q., Chait, A., et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 345 (2001), 1583–1592.
18. 18. White, C.W., Wright, C.B., Doty, D.B., et al. Does visual interpretation of the coronary arteriogram predict the physiologic importance of a coronary stenosis?. N Engl J Med 310 (1984), 819–824.
19. 19. Grondin, C.M., Dyrda, I., Pasternac, A., et al. Discrepancies between cineangiographic and postmortem findings in patients with coronary artery disease and recent myocardial revascularization. Circulation 49 (1974), 703–708.
20. 20. Motoyama, S., Sarai, M., Harigaya, H., et al. Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome. J Am Coll Cardiol 54 (2009), 49–57.
21. 21. Boogers, M.J., Broersen, A., van Velzen, J.E., et al. Automated quantification of coronary plaque with computed tomography: comparison with intravascular ultrasound using a dedicated registration algorithm for fusion-based quantification. Eur Heart J 33 (2012), 1007–1016.
22. 22. de Graaf, M.A., Broersen, A., Kitslaar, P.H., et al. Automatic quantification and characterization of coronary atherosclerosis with computed tomography coronary angiography: cross-correlation with intravascular ultrasound virtual histology. Int J Cardiovasc Imaging 29 (2013), 1177–1190.
23. 23. Fischer, C., Hulten, E., Belur, P., et al. Coronary CT angiography versus intravascular ultrasound for estimation of coronary stenosis and atherosclerotic plaque burden: a meta-analysis. J Cardiovasc Comput Tomogr 7 (2013), 256–266.
24. 24. Hoffmann, U., Moselewski, F., Nieman, K., et al. Noninvasive assessment of plaque morphology and composition in culprit and stable lesions in acute coronary syndrome and stable lesions in stable angina by multidetector computed tomography. J Am Coll Cardiol 47 (2006), 1655–1662.
25. 25. Leipsic, J., Taylor, C.M., Grunau, G., et al. Cardiovascular risk among stable individuals suspected of having coronary artery disease with no modifiable risk factors: results from an international multicenter study of 5262 patients. Radiology 267 (2013), 718–726.
26. 26. Park, H.-B., Lee, B.K., Shin, S., et al. Clinical feasibility of 3D automated coronary atherosclerotic plaque quantification algorithm on coronary computed tomography angiography: comparison with intravascular ultrasound. Eur Radiol, 1-11, 2015.
27. 27. Papadopoulou, S.-L., Garcia-Garcia, H.M., Rossi, A., et al. Reproducibility of computed tomography angiography data analysis using semiautomated plaque quantification software: implications for the design of longitudinal studies. Int J Cardiovasc Imaging 29 (2013), 1095–1104.
28. 28. Meyer, M., Haubenreisser, H., Schoepf, U.J., et al. Closing in on the K Edge: coronary CT angiography at 100, 80, and 70 kv—initial comparison of a second-versus a third-generation dual-source CT system. Radiology 273 (2014), 373–382.
29. 29. Abbara, S., Arbab-Zadeh, A., Callister, T.Q., et al. SCCT guidelines for performance of coronary computed tomographic angiography: a report of the Society of Cardiovascular Computed Tomography Guidelines Committee. J Cardiovasc Comput Tomogr 3 (2009), 190–204.
30. 30. Raff, G.L., Abidov, A., Achenbach, S., et al. SCCT guidelines for the interpretation and reporting of coronary computed tomographic angiography. J Cardiovasc Comput Tomogr 3 (2009), 122–136.
31. 31. Austen, W.G., Edwards, J., Frye, R., et al. A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation, 1975, 5–40.
32. 32. Pontone, G., Andreini, D., Bertella, E., et al. Impact of an intra-cycle motion correction algorithm on overall evaluability and diagnostic accuracy of computed tomography coronary angiography. Eur Radiol 26 (2016), 147–156.
33. 33. Leipsic, J., Abbara, S., Achenbach, S., et al. SCCT guidelines for the interpretation and reporting of coronary CT angiography: a report of the Society of Cardiovascular Computed Tomography Guidelines Committee. J Cardiovasc Comput Tomogr 8 (2014), 342–358.
34. 34. Nakazato, R., Shalev, A., Doh, J.-H., et al. Aggregate plaque volume by coronary computed tomography angiography is superior and incremental to luminal narrowing for diagnosis of ischemic lesions of intermediate stenosis severity. J Am Coll Cardiol 62 (2013), 460–467.
35. 35. Papadopoulou, S.-L., Neefjes, L.A., Garcia-Garcia, H.M., et al. Natural history of coronary atherosclerosis by multislice computed tomography. J Am Coll Cardiol Img 5 (2012), S28–S37.
36. 36. Inoue, K., Motoyama, S., Sarai, M., et al. Serial coronary CT angiography–verified changes in plaque characteristics as an end point: evaluation of effect of statin intervention. J Am Coll Cardiol Img 3 (2010), 691–698.
37. 37. Zeb, I., Li, D., Nasir, K., et al. Effect of statin treatment on coronary plaque progression—a serial coronary CT angiography study. Atherosclerosis 231 (2013), 198–204.
38. 38. Min, J.K., Dunning, A., Lin, F.Y., et al. Age-and sex-related differences in all-cause mortality risk based on coronary computed tomography angiography findings: results from the International Multicenter CONFIRM (Coronary CT Angiography Evaluation for Clinical Outcomes: An International Multicenter Registry) of 23,854 patients without known coronary artery disease. J Am Coll Cardiol 58 (2011), 849–860.
39. 39. Ostrom, M.P., Gopal, A., Ahmadi, N., et al. Mortality incidence and the severity of coronary atherosclerosis assessed by computed tomography angiography. J Am Coll Cardiol 52 (2008), 1335–1343.
40. 40. Calvert, P.A., Obaid, D.R., O'Sullivan, M., et al. Association between IVUS findings and adverse outcomes in patients with coronary artery disease: the VIVA (VH-IVUS in Vulnerable Atherosclerosis) study. J Am Coll Cardiol Img 4 (2011), 894–901.
41. 41. Cheng, J.M., Garcia-Garcia, H.M., de Boer, S.P., et al. In vivo detection of high-risk coronary plaques by radiofrequency intravascular ultrasound and cardiovascular outcome: results of the ATHEROREMO-IVUS study. Eur Heart J 35 (2014), 639–647.
42. 42. Kataoka, Y., Wolski, K., Uno, K., et al. Spotty calcification as a marker of accelerated progression of coronary atherosclerosis: insights from serial intravascular ultrasound. J Am Coll Cardiol 59 (2012), 1592–1597.
43. 43. Uemura, S., K-i, I., Soeda, T., et al. Thin-cap fibroatheroma and microchannel findings in optical coherence tomography correlate with subsequent progression of coronary atheromatous plaques. Eur Heart J 33 (2012), 78–85.
44. 44. Stone, N., Robinson, J., Lichtenstein, A., et al. American College of Cardiology/American Heart Association Task Force on Practice Guidelines. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 63 (2014), 2889–2934.
45. 45. Yamada, M., Jinzaki, M., Tanami, Y., et al. Detection of a coronary artery vessel wall: performance of 0.3 mm fine-cell detector computed tomography—a phantom study. Phys Med Biol, 56, 2011, 5235.
46. 46. Abd-Elmoniem, K.Z., Unsal, A.B., Eshera, S., et al. Increased coronary vessel wall thickness in HIV-infected young adults. Clin Infect Dis 59 (2014), 1779–1786.
47. 47. Braunwald, E., Epilogue: what do clinicians expect from imagers?. J Am Coll Cardiol, 47, 2006, C101.
48. 48. Braunwald, E., Noninvasive detection of vulnerable coronary plaques locking the barn door before the horse is stolen. J Am Coll Cardiol 54 (2009), 58–59.
49. 49. Papadopoulou, S.-L., Neefjes, L.A., Schaap, M., et al. Detection and quantification of coronary atherosclerotic plaque by 64-slice multidetector CT: a systematic head-to-head comparison with intravascular ultrasound. Atherosclerosis 219 (2011), 163–170.
50. 50. Voros, S., Rinehart, S., Qian, Z., et al. Prospective validation of standardized, 3-dimensional, quantitative coronary computed tomographic plaque measurements using radiofrequency backscatter intravascular ultrasound as reference standard in intermediate coronary arterial lesions: results from the ATLANTA (assessment of tissue characteristics, lesion morphology, and hemodynamics by angiography with fractional flow reserve, intravascular ultrasound and virtual histology, and noninvasive computed tomography in atherosclerotic plaques) I study. JACC: Cardiovascular Interventions 4 (2011), 198–208.
51. 51. Hoffmann, H., Frieler, K., Schlattmann, P., et al. Influence of statin treatment on coronary atherosclerosis visualised using multidetector computed tomography. Eur Radiol 20 (2010), 2824–2833.
52. 52. Lo, J., Lu, M.T., Ihenachor, E.J., et al. Effects of statin therapy on coronary artery plaque volume and high-risk plaque morphology in HIV-infected patients with subclinical atherosclerosis: a randomised, double-blind, placebo-controlled trial. Lancet HIV 2 (2015), e52–e63.
53. 53. Burgstahler, C., Reimann, A., Beck, T., et al. Influence of a lipid-lowering therapy on calcified and noncalcified coronary plaques monitored by multislice detector computed tomography: results of the New Age II Pilot Study. Invest Radiol 42 (2007), 189–195.
54. 54. Lehman, S.J., Schlett, C.L., Bamberg, F., et al. Assessment of coronary plaque progression in coronary computed tomography angiography using a semiquantitative score. J Am Coll Cardiol Img 2 (2009), 1262–1270.
55. 55. Motoyama, S., Ito, H., Sarai, M., et al. Plaque characterization by coronary computed tomography angiography and the likelihood of acute coronary events in mid-term follow-up. J Am Coll Cardiol 66 (2015), 337–346.