Lipoic acid use and functional outcomes after thrombolysis in patients with acute ischemic stroke and diabetes

PLoS ONE

Volumn 11, Issue 9, 2016, Pages

  Choi, Kang Ho ^a,b   Park, Man Seok ^b   Kim, Joon Tae ^b   Kim, Hyung Seok ^b   Kim, Ja Hae ^b   Nam, Tai Seung ^a   Choi, Seong Min ^b   Lee, Seung Han ^b   Kim, Byeong Chae ^b   Kim, Myeong Kyu ^b   Cho, Ki Hyun ^b  

^a Chonnam National University Research Institute of Medical Sciences   (South Korea)

^b Chonnam National University Medical School   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

THIOCTIC ACID; TISSUE PLASMINOGEN ACTIVATOR;

AGE; AGED; ARTICLE; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEUROPATHY; EARLY CLINICAL IMPROVEMENT; EARLY NEUROLOGICAL DETERIORATION; FEMALE; FIBRINOLYTIC THERAPY; FUNCTIONAL STATUS; HEMORRHAGIC TRANSFORMATION; HUMAN; MAJOR CLINICAL STUDY; MALE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NUCLEAR MAGNETIC RESONANCE IMAGING; RANKIN SCALE; RETROSPECTIVE STUDY;

EID: 84991666110     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0163484     Document Type: Article

References (29)

1. Jauch EC, Saver JL, Adams HP Jr., Bruno A, Connors JJ, Demaerschalk BM, et al. Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013; 44(3):870-947. doi: 10.1161/STR.0b013e318284056a PMID: 23370205
2. Chan PH. Role of oxidants in ischemic brain damage. Stroke. 1996; 27(6):1124-9. PMID: 8650725
3. Pradeep H, Diya JB, Shashikumar S, Rajanikant GK. Oxidative stress - assassin behind the ischemic stroke. Folia Neuropathol. 2012; 50(3):219-30. PMID: 23023336
4. Sugawara T, Chan PH. Reactive oxygen radicals and pathogenesis of neuronal death after cerebral ischemia. Antioxid Redox Signal. 2003; 5(5):597-607. doi: 10.1089/152308603770310266 PMID: 14580316
5. Choi KH, Park MS, Kim HS, Kim KT, Kim HS, Kim JT, et al. Alpha-lipoic acid treatment is neurorestorative and promotes functional recovery after stroke in rats. Mol Brain. 2015; 8:9. doi: 10.1186/s13041-015-0101-6 PMID: 25761600
6. Zhao L, Hu FX. alpha-Lipoic acid treatment of aged type 2 diabetes mellitus complicated with acute cerebral infarction. Eur Rev Med Pharmacol Sci. 2014; 18(23):3715-9. PMID: 25535146.
7. Whitworth JA, World Health Organization ISoHWG. 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. J Hypertens. 2003; 21(11):1983-92. doi: 10.1097/01.hjh.0000084751.37215.d2 PMID: 14597836.
8. Brott T, Adams HP Jr., Olinger CP, Marler JR, Barsan WG, Biller J, et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke. 1989; 20(7):864-70. PMID: 2749846.
9. Bonita R, Beaglehole R. Recovery of motor function after stroke. Stroke. 1988; 19(12):1497-500. PMID: 3201508.
10. Weimar C, Mieck T, Buchthal J, Ehrenfeld CE, Schmid E, Diener HC, et al. Neurologic worsening during the acute phase of ischemic stroke. Arch Neurol. 2005; 62(3):393-7. doi: 10.1001/archneur.62.3.393 PMID: 15767504.
11. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. 1995; 333(24):1581-7. doi: 10.1056/NEJM199512143332401 PMID: 7477192.
12. Adams HP Jr., Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993; 24(1):35-41. PMID: 7678184.
13. Kernan WN, Ovbiagele B, Black HR, Bravata DM, Chimowitz MI, Ezekowitz MD, et al. Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014; 45 (7):2160-236. doi: 10.1161/STR.0000000000000024 PMID: 24788967.
14. Kaku M, Vinik A, Simpson DM. Pathways in the diagnosis and management of diabetic polyneuropathy. Curr Diab Rep. 2015; 15(6):609. doi: 10.1007/s11892-015-0609-2 PMID: 25899758.
15. Savitz SI, Lew R, Bluhmki E, Hacke W, Fisher M. Shift analysis versus dichotomization of the modified Rankin scale outcome scores in the NINDS and ECASS-II trials. Stroke. 2007; 38(12):3205-12. doi: 10.1161/STROKEAHA.107.489351 PMID: 17975102.
16. Biewenga GP, Haenen GR, Bast A. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol. 1997; 29(3):315-31. S0306362396004740 PMID: 9378235.
17. Moini H, Packer L, Saris NE. Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid. Toxicol Appl Pharmacol. 2002; 182(1):84-90. S0041008X02994378 PMID: 12127266.
18. Heitzer T, Finckh B, Albers S, Krohn K, Kohlschutter A, Meinertz T. Beneficial effects of alpha-lipoic acid and ascorbic acid on endothelium-dependent, nitric oxide-mediated vasodilation in diabetic patients: relation to parameters of oxidative stress. Free Radic Biol Med. 2001; 31(1):53-61. S0891584901005512 PMID: 11425490.
19. Pompella A, Visvikis A, Paolicchi A, De Tata V, Casini AF. The changing faces of glutathione, a cellular protagonist. Biochem Pharmacol. 2003; 66(8):1499-503 PMID: 14555227.
20. Hung LM, Huang JP, Liao JM, Yang MH, Li DE, Day YJ, et al. Insulin renders diabetic rats resistant to acute ischemic stroke by arresting nitric oxide reaction with superoxide to form peroxynitrite. Journal of biomedical science. 2014; 21:92. doi: 10.1186/s12929-014-0092-0 PMID: 25223305.
21. Yang D, Nakajo Y, Iihara K, Kataoka H, Yanamoto H. Alogliptin, a dipeptidylpeptidase-4 inhibitor, for patients with diabetes mellitus type 2, induces tolerance to focal cerebral ischemia in non-diabetic, normal mice. Brain Res. 2013; 1517:104-13. doi: 10.1016/j.brainres.2013.04.015 PMID: 23602966.
22. Teramoto S, Miyamoto N, Yatomi K, Tanaka Y, Oishi H, Arai H, et al. Exendin-4, a glucagon-like peptide-1 receptor agonist, provides neuroprotection in mice transient focal cerebral ischemia. J Cereb Blood Flow Metab. 2011; 31(8):1696-705. doi: 10.1038/jcbfm.2011.51 PMID: 21487412.
23. Schreibelt G, Musters RJ, Reijerkerk A, de Groot LR, van der Pol SM, Hendrikx EM, et al. Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity. J Immunol. 2006; 177(4):2630-7 PMID: 16888025.
24. Warach S, Latour LL. Evidence of reperfusion injury, exacerbated by thrombolytic therapy, in human focal brain ischemia using a novel imaging marker of early blood-brain barrier disruption. Stroke. 2004; 35(11 Suppl 1):2659-61. doi: 10.1161/01.STR.0000144051.32131.09 PMID: 15472105.
25. Simard JM, Kent TA, Chen M, Tarasov KV, Gerzanich V. Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. Lancet Neurol. 2007; 6(3):258-68. doi: 10.1016/S1474-4422(07)70055-8 PMID: 17303532.
26. Choi KH, Kim HS, Park MS, Kim JT, Kim JH, Cho KA, et al. Regulation of Caveolin-1 Expression Determines Early Brain Edema After Experimental Focal Cerebral Ischemia. Stroke. 2016; 47(5):1336-43. doi: 10.1161/STROKEAHA.116.013205 PMID: 27012742.
27. Kim JT, Park MS, Nam TS, Choi SM, Kim BC, Kim MK, et al. Thrombolysis as a factor associated with favorable outcomes in patients with unclear-onset stroke. Eur J Neurol. 2011; 18(7):988-94. doi: 10.1111/j.1468-1331.2011.03351.x PMID: 21299733.
28. Kablau M, Kreisel SH, Sauer T, Binder J, Szabo K, Hennerici MG, et al. Predictors and early outcome of hemorrhagic transformation after acute ischemic stroke. Cerebrovasc Dis. 2011; 32(4):334-41. doi: 10.1159/000331702 PMID: 21921596.
29. Dovinova I, Novotny L, Rauko P, Kvasnicka P. Combined effect of lipoic acid and doxorubicin in murine leukemia. Neoplasma. 1999; 46(4):237-41 PMID: 10613604.