Agonistic autoantibodies to the angiotensin II type 1 receptor enhance angiotensin II-induced renal vascular sensitivity and reduce renal function during pregnancy

Hypertension

Volumn 68, Issue 5, 2016, Pages 1308-1313

  Cunningham, Mark W ^a   Williams, Jan M ^a   Amaral, Lorena ^a   Usry, Nathan ^a   Wallukat, Gerd ^b   Dechend, Ralf ^c   Lamarca, Babbette ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c Experimental and Clinical Research Center   (Germany)

Author keywords

angiotensin II; autoantibodies; hypertension; preeclampsia; pregnancy

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; AUTOANTIBODY; ISOPROSTANE DERIVATIVE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GLOMERULUS FILTRATION RATE; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY VASCULAR RESISTANCE; MEAN ARTERIAL PRESSURE; NONHUMAN; OSMOTIC PUMP; PREGNANCY; PRIORITY JOURNAL; RAT; ANALYSIS OF VARIANCE; ANIMAL; BREEDING; COMPARATIVE STUDY; DRUG EFFECTS; HUMAN; HYPERTENSION, PREGNANCY-INDUCED; IMMUNOLOGY; KIDNEY FUNCTION TEST; OXIDATIVE STRESS; PHYSIOLOGY; PLACENTA CIRCULATION; PREGNANCY OUTCOME;

ANALYSIS OF VARIANCE; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; AUTOANTIBODIES; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; HYPERTENSION, PREGNANCY-INDUCED; KIDNEY FUNCTION TESTS; OXIDATIVE STRESS; PLACENTAL CIRCULATION; PREGNANCY; PREGNANCY OUTCOME; PREGNANCY, ANIMAL; RATS; RECEPTOR, ANGIOTENSIN, TYPE 1;

EID: 84991463721     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.116.07971     Document Type: Article

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