메뉴 건너뛰기




Volumn 2015, Issue 8, 2015, Pages

Pharmacological treatments for preventing epilepsy following traumatic head injury

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; LEVETIRACETAM; MAGNESIUM SULFATE; NEUROPROTECTIVE AGENT; PHENYTOIN; PLACEBO; VALPROIC ACID; ETIRACETAM; PIRACETAM;

EID: 84991243766     PISSN: None     EISSN: 1469493X     Source Type: Journal    
DOI: 10.1002/14651858.CD009900.pub2     Document Type: Review
Times cited : (106)

References (112)
  • 1
    • 0020580409 scopus 로고
    • Seizure prevention using carbamazepine following severe brain injuries
    • Anfallsprophylaxe mit Carbamazepin nach schweren Schadelhirnverletzungen
    • Glotzner FL, Haubitz I, Miltner F, Kapp G, Pflughaupt K-W. Seizure prevention using carbamazepine following severe brain injuries [Anfallsprophylaxe mit Carbamazepin nach schweren Schadelhirnverletzungen]. Neurochirurgia 1983;26(3):66-79.
    • (1983) Neurochirurgia , vol.26 , Issue.3 , pp. 66-79
    • Glotzner, F.L.1    Haubitz, I.2    Miltner, F.3    Kapp, G.4    Pflughaupt, K.-W.5
  • 2
    • 0026793130 scopus 로고
    • Cooperative prospective study on posttraumatic epilepsy: risk factors and the effect of prophylactic anticonvulsant
    • Manaka S. Cooperative prospective study on posttraumatic epilepsy: risk factors and the effect of prophylactic anticonvulsant. Japanese Journal of Psychiatry and Neurology 1992;46(2):311-5.
    • (1992) Japanese Journal of Psychiatry and Neurology , vol.46 , Issue.2 , pp. 311-315
    • Manaka, S.1
  • 3
    • 34548003743 scopus 로고
    • The incidence and the possible pharmacological prophylaxis of post-traumatic epilepsy [abstract]
    • Harris P, Kalbag RM, McQueen JK, Blackwood DHR, Johnson AL. The incidence and the possible pharmacological prophylaxis of post-traumatic epilepsy [abstract]. Acta Neurochirurgica 1984;70(1-2):132.
    • (1984) Acta Neurochirurgica , vol.70 , Issue.1-2 , pp. 132
    • Harris, P.1    Kalbag, R.M.2    McQueen, J.K.3    Blackwood, D.H.R.4    Johnson, A.L.5
  • 5
    • 0025001919 scopus 로고
    • Hydantoins in the prevention of early posttraumatic epileptic crises
    • Prevention des crises d'epilepsie posttraumatiques precoces par les hydantoines
    • Lauxerois M, Pechadre JC, Colnet G, Commun C, Bonnard M. Hydantoins in the prevention of early posttraumatic epileptic crises [Prevention des crises d'epilepsie posttraumatiques precoces par les hydantoines]. Epilepsies 1990;2(1):5-10.
    • (1990) Epilepsies , vol.2 , Issue.1 , pp. 5-10
    • Lauxerois, M.1    Pechadre, J.C.2    Colnet, G.3    Commun, C.4    Bonnard, M.5
  • 6
    • 0026422321 scopus 로고
    • Prevention of late post-traumatic epilepsy by phenytoin in severe brain injuries, 2 years' follow-up
    • Prevention de l'epilepsie post-traumatique tardive par phenytoine dans les traumatismes craniens graves, suivi durant 2 ans
    • Pechadre JC, Lauxerois M, Colnet G, Commun C, Bonnard M, Gilbert J, et al. Prevention of late post-traumatic epilepsy by phenytoin in severe brain injuries, 2 years' follow-up [Prevention de l'epilepsie post-traumatique tardive par phenytoine dans les traumatismes craniens graves, suivi durant 2 ans]. Presse Medicale 1991;20(18):841-5.
    • (1991) Presse Medicale , vol.20 , Issue.18 , pp. 841-845
    • Pechadre, J.C.1    Lauxerois, M.2    Colnet, G.3    Commun, C.4    Bonnard, M.5    Gilbert, J.6
  • 7
    • 85041704295 scopus 로고    scopus 로고
    • Assess the safety and efficacy of a seizure medication, levetiracetam (LEV; Keppra), in neuroscience intensive care unit patients
    • (accessed 11 February 2014) NCT00618436
    • NCT00618436. Assess the safety and efficacy of a seizure medication, levetiracetam (LEV; Keppra), in neuroscience intensive care unit patients. www.clinicaltrials.gov/ct2/show/NCT00618436 (accessed 11 February 2014).
  • 8
    • 84858281856 scopus 로고    scopus 로고
    • Initial EEG predicts outcomes in a trial of levetiracetam vs. fosphenytoin for seizure prevention
    • Steinbaugh LA, Lindsell CJ, Shutter LA, Szaflarski JP. Initial EEG predicts outcomes in a trial of levetiracetam vs. fosphenytoin for seizure prevention. Epilepsy & Behavior 2012;23(3):280-4.
    • (2012) Epilepsy & Behavior , vol.23 , Issue.3 , pp. 280-284
    • Steinbaugh, L.A.1    Lindsell, C.J.2    Shutter, L.A.3    Szaflarski, J.P.4
  • 9
    • 77953609500 scopus 로고    scopus 로고
    • Prospective, randomized, single-blinded comparative trial of intravenous levetiracetam versus phenytoin for seizure prophylaxis
    • Szaflarski JP, Sangha KS, Lindsell CJ, Shutter LA. Prospective, randomized, single-blinded comparative trial of intravenous levetiracetam versus phenytoin for seizure prophylaxis. Neurocritical Care 2010;12(2):165-72.
    • (2010) Neurocritical Care , vol.12 , Issue.2 , pp. 165-172
    • Szaflarski, J.P.1    Sangha, K.S.2    Lindsell, C.J.3    Shutter, L.A.4
  • 10
    • 0033500760 scopus 로고    scopus 로고
    • Side effects and mortality associated with use of phenytoin for early posttraumatic seizure prophylaxis
    • Haltiner AM, Newell DW, Temkin NR, Dikmen SS, Winn HR. Side effects and mortality associated with use of phenytoin for early posttraumatic seizure prophylaxis. Journal of Neurosurgery 1999;91(4):588-92.
    • (1999) Journal of Neurosurgery , vol.91 , Issue.4 , pp. 588-592
    • Haltiner, A.M.1    Newell, D.W.2    Temkin, N.R.3    Dikmen, S.S.4    Winn, H.R.5
  • 11
    • 0012111369 scopus 로고
    • Does phenytoin prevent posttraumatic seizures -1-year follow-up results of a randomized double-blind-study in 407 patients [abstract]
    • Temkin NR, Dikmen SS, Keihm J, Chabal S, Winn HR. Does phenytoin prevent posttraumatic seizures -1-year follow-up results of a randomized double-blind-study in 407 patients [abstract]. Journal of Neurosurgery 1989;70(2):314A-315A.
    • (1989) Journal of Neurosurgery , vol.70 , Issue.2 , pp. 314A-315A
    • Temkin, N.R.1    Dikmen, S.S.2    Keihm, J.3    Chabal, S.4    Winn, H.R.5
  • 13
    • 85041734471 scopus 로고    scopus 로고
    • Phase III double blind trial of valproate sodium for prophylaxis of post traumatic seizures
    • (accessed 11 February 2014)
    • NCT00004817. Phase III double blind trial of valproate sodium for prophylaxis of post traumatic seizures. www.clinicaltrials.gov/ct2/show/record/NCT00004817 (accessed 11 February 2014).
  • 15
  • 16
    • 0020672024 scopus 로고
    • Failure of prophylactically administered phenytoin to prevent early posttraumatic seizures
    • Young B, Rapp RP, Norton JA, Haack D, Tibbs PA, Bean JB. Failure of prophylactically administered phenytoin to prevent early posttraumatic seizures. Journal of Neurosurgery 1983;58(2):231-5.
    • (1983) Journal of Neurosurgery , vol.58 , Issue.2 , pp. 231-235
    • Young, B.1    Rapp, R.P.2    Norton, J.A.3    Haack, D.4    Tibbs, P.A.5    Bean, J.B.6
  • 17
  • 18
    • 0020964853 scopus 로고
    • Failure of prophylatically administered to prevent post-traumatic seizures in children
    • Young B, Rapp RP, Norton JA, Haack D, Walsh JW. Failure of prophylatically administered to prevent post-traumatic seizures in children. Child's Brain 1983;10(3):1985-92.
    • (1983) Child's Brain , vol.10 , Issue.3 , pp. 1985-1992
    • Young, B.1    Rapp, R.P.2    Norton, J.A.3    Haack, D.4    Walsh, J.W.5
  • 19
    • 12144289127 scopus 로고    scopus 로고
    • A randomized, double-blinded, placebo-controlled trial of phenytoin for the prevention of early posttraumatic seizures in children with moderate to severe blunt head injury
    • Young KD, Okada PJ, Sokolove PE, Palchak MJ, Panacek EA, Baren JM, et al. A randomized, double-blinded, placebo-controlled trial of phenytoin for the prevention of early posttraumatic seizures in children with moderate to severe blunt head injury. Annals of Emergency Medicine 2004;43(4):435-46.
    • (2004) Annals of Emergency Medicine , vol.43 , Issue.4 , pp. 435-446
    • Young, K.D.1    Okada, P.J.2    Sokolove, P.E.3    Palchak, M.J.4    Panacek, E.A.5    Baren, J.M.6
  • 20
    • 0034045890 scopus 로고    scopus 로고
    • Incidence of intravenous site reactions in neurotrauma patients receiving valproate or phenytoin
    • Anderson GD, Lin Y, Temkin NR, Fischer JH, Winn RH. Incidence of intravenous site reactions in neurotrauma patients receiving valproate or phenytoin. Annals of Pharmacotherapy 2000;34(6):697-702.
    • (2000) Annals of Pharmacotherapy , vol.34 , Issue.6 , pp. 697-702
    • Anderson, G.D.1    Lin, Y.2    Temkin, N.R.3    Fischer, J.H.4    Winn, R.H.5
  • 21
    • 0842330649 scopus 로고    scopus 로고
    • Effect of valproate on hemostatic function in patients with traumatic brain injury
    • Anderson GD, Temkin NR, Chandler WL, Winn HR. Effect of valproate on hemostatic function in patients with traumatic brain injury. Epilepsy Research 2003;57(2-3):111-19.
    • (2003) Epilepsy Research , vol.57 , Issue.2-3 , pp. 111-119
    • Anderson, G.D.1    Temkin, N.R.2    Chandler, W.L.3    Winn, H.R.4
  • 22
    • 0032943602 scopus 로고    scopus 로고
    • Early and late posttraumatic seizures in traumatic brain injury rehabilitation patients: brain injury factors causing late seizures and influence of seizures on long-term outcome
    • Asikainen I, Kaste M, Sarna Seppo. Early and late posttraumatic seizures in traumatic brain injury rehabilitation patients: brain injury factors causing late seizures and influence of seizures on long-term outcome. Epilepsia 1999;40(5):584-9.
    • (1999) Epilepsia , vol.40 , Issue.5 , pp. 584-589
    • Asikainen, I.1    Kaste, M.2    Sarna, S.3
  • 23
    • 85027905145 scopus 로고    scopus 로고
    • Evaluation of the use of phenytoin and levetiracetam for seizure prophylaxis in patients with traumatic brain injury
    • Carter D, Askari R, Frawley B, Rogers S. Evaluation of the use of phenytoin and levetiracetam for seizure prophylaxis in patients with traumatic brain injury. Critical Care Medicine 2009;37(12 Suppl):A77, Abstract no: 185.
    • (2009) Critical Care Medicine , vol.37 , Issue.12 , pp. A77
    • Carter, D.1    Askari, R.2    Frawley, B.3    Rogers, S.4
  • 25
    • 0036898720 scopus 로고    scopus 로고
    • Randomized evaluation of adverse events and length-of-stay with routine emergency department use of phenytoin or fosphenytoin
    • Coplin WM, Rhoney DH, Rebuck JA, Clements EA, Cochran MS, O'Neil BJ. Randomized evaluation of adverse events and length-of-stay with routine emergency department use of phenytoin or fosphenytoin. Neurological Research 2002;24(8):842-8.
    • (2002) Neurological Research , vol.24 , Issue.8 , pp. 842-848
    • Coplin, W.M.1    Rhoney, D.H.2    Rebuck, J.A.3    Clements, E.A.4    Cochran, M.S.5    O'Neil, B.J.6
  • 29
    • 0026062248 scopus 로고
    • Neurobehavioral effects of phenytoin prophylaxis of posttraumatic seizures
    • Dikmen SS, Temkin NR, Miller B, Machamer J, Winn HR. Neurobehavioral effects of phenytoin prophylaxis of posttraumatic seizures. JAMA 1991;265(10):1271-7.
    • (1991) JAMA , vol.265 , Issue.10 , pp. 1271-1277
    • Dikmen, S.S.1    Temkin, N.R.2    Miller, B.3    Machamer, J.4    Winn, H.R.5
  • 30
    • 85041726077 scopus 로고
    • Neurobehavioral effects of phenytoin prophylaxis in posttraumatic seizures: a double-blind comparison [abstract]
    • Dikmen SS, Temkin NR, Winn HR. Neurobehavioral effects of phenytoin prophylaxis in posttraumatic seizures: a double-blind comparison [abstract]. Epilepsia 1989;30(5):667.
    • (1989) Epilepsia , vol.30 , Issue.5 , pp. 667
    • Dikmen, S.S.1    Temkin, N.R.2    Winn, H.R.3
  • 32
    • 0034700968 scopus 로고    scopus 로고
    • Neuropsychological effects of valproate in traumatic brain injury: a randomized trial
    • Dikmen SS, Machamer JE, Winn HR, Anderson DG, Temkin NR. Neuropsychological effects of valproate in traumatic brain injury: a randomized trial. Neurology 2000;54(4):895-902.
    • (2000) Neurology , vol.54 , Issue.4 , pp. 895-902
    • Dikmen, S.S.1    Machamer, J.E.2    Winn, H.R.3    Anderson, D.G.4    Temkin, N.R.5
  • 33
    • 84856453003 scopus 로고    scopus 로고
    • Modified Lund concept versus cerebral perfusion pressure-targeted therapy: a randomised controlled study in patients with secondary brain ischaemia
    • Dizdarevic K, Hamdan A, Omerhodzic I, Kominlija-Smajic E. Modified Lund concept versus cerebral perfusion pressure-targeted therapy: a randomised controlled study in patients with secondary brain ischaemia. Clinical Neurology and Neurosurgery 2012;114(2):142-8.
    • (2012) Clinical Neurology and Neurosurgery , vol.114 , Issue.2 , pp. 142-148
    • Dizdarevic, K.1    Hamdan, A.2    Omerhodzic, I.3    Kominlija-Smajic, E.4
  • 34
    • 85041737386 scopus 로고    scopus 로고
    • Determination of the efficacy of phenytoin on prevention of late post-traumatic seizure
    • Dolati P, Akhtar SM, Ziabary SM. Determination of the efficacy of phenytoin on prevention of late post-traumatic seizure. Journal of Neurology 2012;259(1):S15.
    • (2012) Journal of Neurology , vol.259 , Issue.1 , pp. S15
    • Dolati, P.1    Akhtar, S.M.2    Ziabary, S.M.3
  • 36
  • 37
    • 85041725335 scopus 로고    scopus 로고
    • Epilepsy prophylaxis with carbamazepine in severe brain injury [abstract]
    • Glotzner FL. Epilepsy prophylaxis with carbamazepine in severe brain injury [abstract]. Epilepsia 1998;39(Suppl 2):48.
    • (1998) Epilepsia , vol.39 , pp. 48
    • Glotzner, F.L.1
  • 41
    • 84874878371 scopus 로고    scopus 로고
    • A prospective multicenter comparison of levetiracetam versus phenytoin for early posttraumatic seizure prophylaxis
    • Inaba K, Menaker J, Branco BC, Gooch J, Okoye OT, Herrold J, et al. A prospective multicenter comparison of levetiracetam versus phenytoin for early posttraumatic seizure prophylaxis. Journal of Trauma and Acute Care Surgery 2013;74(3):766-71.
    • (2013) Journal of Trauma and Acute Care Surgery , vol.74 , Issue.3 , pp. 766-771
    • Inaba, K.1    Menaker, J.2    Branco, B.C.3    Gooch, J.4    Okoye, O.T.5    Herrold, J.6
  • 43
    • 0026343937 scopus 로고
    • [The factors influencing posttraumatic epilepsy: a multicentric cooperative study]
    • [PUBMED: 1766540]
    • Japan Follow-up Group for Posttraumatic Epilepsy. [The factors influencing posttraumatic epilepsy: a multicentric cooperative study]. No shinkei geka [Neurological Surgery] 1991;19(12):1151-9. [PUBMED: 1766540]
    • (1991) No shinkei geka [Neurological Surgery] , vol.19 , Issue.12 , pp. 1151-1159
  • 44
    • 85041744695 scopus 로고    scopus 로고
    • Retrospective comparison of the cost and effectiveness of levetiracetam versus phenytoin for seizure prophylaxis
    • Johnson D, Rottman K, De Los Santos M. Retrospective comparison of the cost and effectiveness of levetiracetam versus phenytoin for seizure prophylaxis. Critical Care Medicine 2009;37(12 Suppl):A475, Abstract no: 968.
    • (2009) Critical Care Medicine , vol.37 , Issue.12 , pp. A475
    • Johnson, D.1    Rottman, K.2    De Los Santos, M.3
  • 46
    • 0034843923 scopus 로고    scopus 로고
    • Anticonvulsive prophylaxis of posttraumatic epilepsy in childhood
    • Antikonvulsive Prophylaxe der posttraumatischen Epilepsie im Kindersalter
    • Kieslich M, Born A, Jacobi G. Anticonvulsive prophylaxis of posttraumatic epilepsy in childhood [Antikonvulsive Prophylaxe der posttraumatischen Epilepsie im Kindersalter]. Aktuelle Neurologie 2001;28(7):313-8.
    • (2001) Aktuelle Neurologie , vol.28 , Issue.7 , pp. 313-318
    • Kieslich, M.1    Born, A.2    Jacobi, G.3
  • 47
    • 84889684298 scopus 로고    scopus 로고
    • Role of intravenous levetiracetam in seizure prophylaxis of severe traumatic brain injury patients
    • Kirmani BF, Mungall D, Ling G. Role of intravenous levetiracetam in seizure prophylaxis of severe traumatic brain injury patients. Fontiers in Neurology 2013;4:1-4.
    • (2013) Fontiers in Neurology , vol.4 , pp. 1-4
    • Kirmani, B.F.1    Mungall, D.2    Ling, G.3
  • 48
    • 78650148301 scopus 로고    scopus 로고
    • Safety, tolerability and pharmacokinetics of levetiracetam in patients with acute traumatic brain injury with high risk [abstract]
    • Klein P, Herr D, Pearl PL, Sandoval F, Trzcinski S, Nogay C, et al. Safety, tolerability and pharmacokinetics of levetiracetam in patients with acute traumatic brain injury with high risk [abstract]. Epilepsia 2008;49(Suppl s7):81, Abstract no: 1.187.
    • (2008) Epilepsia , vol.49 , pp. 81
    • Klein, P.1    Herr, D.2    Pearl, P.L.3    Sandoval, F.4    Trzcinski, S.5    Nogay, C.6
  • 49
    • 84867378769 scopus 로고    scopus 로고
    • Results of phase 2 safety and feasibility study of treatment with levetiracetam for prevention of posttraumatic epilepsy
    • Klein P, Herr D, Pearl PL, Natale J, Levine Z, Nogay C, et al. Results of phase 2 safety and feasibility study of treatment with levetiracetam for prevention of posttraumatic epilepsy. Archives of Neurology 2012;69(10):1290-5.
    • (2012) Archives of Neurology , vol.69 , Issue.10 , pp. 1290-1295
    • Klein, P.1    Herr, D.2    Pearl, P.L.3    Natale, J.4    Levine, Z.5    Nogay, C.6
  • 50
    • 84864302215 scopus 로고    scopus 로고
    • Results of phase II pharmacokinetic study of levetiracetam for prevention of post-traumatic epilepsy
    • Klein P, Herr D, Pearl PL, Natale J, Levine Z, Nogay C, et al. Results of phase II pharmacokinetic study of levetiracetam for prevention of post-traumatic epilepsy. Epilepsy & Behavior 2012;24:457-61.
    • (2012) Epilepsy & Behavior , vol.24 , pp. 457-461
    • Klein, P.1    Herr, D.2    Pearl, P.L.3    Natale, J.4    Levine, Z.5    Nogay, C.6
  • 51
    • 0030812887 scopus 로고    scopus 로고
    • Cooperative multicentre study on postraumatic epilepsy
    • Kobayashi M. Cooperative multicentre study on postraumatic epilepsy. Brain and Nerve 1997;49(8):723-7.
    • (1997) Brain and Nerve , vol.49 , Issue.8 , pp. 723-727
    • Kobayashi, M.1
  • 52
    • 85041718151 scopus 로고    scopus 로고
    • Post traumatic epilepsy: a follow-up of 20 years
    • Lopes J, Santos A, Martins da Silva A. Post traumatic epilepsy: a follow-up of 20 years. Epilepsia 2009;50(Suppl 4):160, Abstract no: E411.
    • (2009) Epilepsia , vol.50 , pp. 160
    • Lopes, J.1    Santos, A.2    Martins da Silva, A.3
  • 53
    • 29044436727 scopus 로고    scopus 로고
    • Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial
    • Maas AIR, Murry G, Henney H 3rd, Kassem N, Legrand V, Mangelus M, et al. Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial. Lancet Neurology 2006;5(1):38-45.
    • (2006) Lancet Neurology , vol.5 , Issue.1 , pp. 38-45
    • Maas, A.I.R.1    Murry, G.2    Henney, H.3    Kassem, N.4    Legrand, V.5    Mangelus, M.6
  • 54
    • 85041708765 scopus 로고    scopus 로고
    • Levetiracetam in patients with post-traumatic epilepsy: observations in a case series
    • Meo R, Bilo L, de Leva MF. Levetiracetam in patients with post-traumatic epilepsy: observations in a case series. Epilepsia 2009;50(Suppl. 11):106, Abstract no: 1.215.
    • (2009) Epilepsia , vol.50 , pp. 106
    • Meo, R.1    Bilo, L.2    de Leva, M.F.3
  • 57
    • 0029610279 scopus 로고
    • Cooperative multicentre study on postraumatic epilepsy
    • Nakamura N. Cooperative multicentre study on postraumatic epilepsy. Brain and Nerve 1995;47(12):1170-6.
    • (1995) Brain and Nerve , vol.47 , Issue.12 , pp. 1170-1176
    • Nakamura, N.1
  • 58
    • 0032841505 scopus 로고    scopus 로고
    • A randomized controlled trial of zonisamide in postoperative epilepsy: a report of the cooperative group study
    • Nakamura N, Ishijima B, Mayanagi Y, Manaka S. A randomized controlled trial of zonisamide in postoperative epilepsy: a report of the cooperative group study. Japanese Journal of Neurosurgery 1999;8(10):647-56.
    • (1999) Japanese Journal of Neurosurgery , vol.8 , Issue.10 , pp. 647-656
    • Nakamura, N.1    Ishijima, B.2    Mayanagi, Y.3    Manaka, S.4
  • 59
    • 85041735186 scopus 로고    scopus 로고
    • Prospective, randomized, double-blind study assessing the effects of levetiracetam compared to placebo in the prevention of early epileptic seizures and late epilepsy in patients with severe traumatic brain injury
    • (accessed 11 February 2014)
    • NCT00566046. Prospective, randomized, double-blind study assessing the effects of levetiracetam compared to placebo in the prevention of early epileptic seizures and late epilepsy in patients with severe traumatic brain injury. www.clinicaltrials.gov/ct/show/NCT00566046 (accessed 11 February 2014).
  • 60
    • 85041713801 scopus 로고    scopus 로고
    • Preventing epilepsy after traumatic brain injury with topiramate (PEPTO)
    • (accessed 11 February 2014)
    • NCT00598923. Preventing epilepsy after traumatic brain injury with topiramate (PEPTO). www.clinicaltrials.gov/ct/show/NCT00598923 (accessed 11 February 2014).
  • 61
    • 85041700985 scopus 로고    scopus 로고
    • A pilot study of NSICU assessment of seizure prophylaxis with lacosamide
    • (accessed 11 February 2014)
    • NCT01110187. A pilot study of NSICU assessment of seizure prophylaxis with lacosamide. clinicaltrials.gov/show/NCT01110187 (accessed 11 February 2014).
    • clinicaltrials.gov/show/NCT01110187
  • 62
  • 64
    • 85047697910 scopus 로고    scopus 로고
    • Repinotan (BAY x 3702): a 5HT1A agonist in traumatically brain injured patients
    • Ohman J, Braakman R, Legout V, Traumatic Brain Injury Study Group. Repinotan (BAY x 3702): a 5HT1A agonist in traumatically brain injured patients. Journal of Neurotrauma 2001;18(12):1313-21.
    • (2001) Journal of Neurotrauma , vol.18 , Issue.12 , pp. 1313-1321
    • Ohman, J.1    Braakman, R.2    Legout, V.3
  • 66
    • 85041717366 scopus 로고    scopus 로고
    • Results of phase II NIH study of levetiracetam for the prevention of pediatric post-traumatic epilepsy (PTE)
    • Pearl PL, Tsuchida T, McCarter R, Pettiford JM, Sandoval F, Trzcinski S, et al. Results of phase II NIH study of levetiracetam for the prevention of pediatric post-traumatic epilepsy (PTE). Annals of Neurology 2009;66(Suppl S1):S122, Abstract no: 81.
    • (2009) Annals of Neurology , vol.66 , pp. S122
    • Pearl, P.L.1    Tsuchida, T.2    McCarter, R.3    Pettiford, J.M.4    Sandoval, F.5    Trzcinski, S.6
  • 67
    • 84883741122 scopus 로고    scopus 로고
    • Results of phase II levetiracetam trial following head injury in children at risk for posttraumatic epilepsy
    • Pearl PL, McCarter R, McGavin CL, Yu Y, Sandoval F, Trzcinsky S, et al. Results of phase II levetiracetam trial following head injury in children at risk for posttraumatic epilepsy. Epilepsia 2013;59(9):135-7.
    • (2013) Epilepsia , vol.59 , Issue.9 , pp. 135-137
    • Pearl, P.L.1    McCarter, R.2    McGavin, C.L.3    Yu, Y.4    Sandoval, F.5    Trzcinsky, S.6
  • 68
    • 0001434826 scopus 로고
    • A controlled prospective study of the pharmacologic prophylaxis of posttraumatic epilepsy
    • Penry JK, White BG, Bracket CE. A controlled prospective study of the pharmacologic prophylaxis of posttraumatic epilepsy. Neurology 1979;29(4):600-1.
    • (1979) Neurology , vol.29 , Issue.4 , pp. 600-601
    • Penry, J.K.1    White, B.G.2    Bracket, C.E.3
  • 69
    • 0014446962 scopus 로고
    • Klindky pokus o prevenci posttraumaticke epidelpsie po tezkych zranenick mozku u dospelych
    • [PUBMED: 4976099]
    • Popek K, Musil F. Clinical attempt to prevent post-traumatic epilepsy following severe brain injuries in adults [Klindky pokus o prevenci posttraumaticke epidelpsie po tezkych zranenick mozku u dospelych]. Casopis Lekaru Ceskych 1969;108(5):133-47. [PUBMED: 4976099]
    • (1969) Casopis Lekaru Ceskych , vol.108 , Issue.5 , pp. 133-147
    • Popek, K.1    Musil, F.2
  • 70
    • 0015468657 scopus 로고
    • Prevence posttraumaticke eplilepsi po tezkych zranenich mozku
    • [PUBMED: 5044144]
    • Popek K. Preventative treatment of post-traumatic epilepsy following severe brain injury. Closing report summarizing results of the research done in the framework of the state research plan for the years 1965-1969; edited by Z. Servit [Prevence posttraumaticke eplilepsi po tezkych zranenich mozku]. Ceskoslovenska Neurologie 1972;35(4):169-74. [PUBMED: 5044144]
    • (1972) Ceskoslovenska Neurologie , vol.35 , Issue.4 , pp. 169-174
    • Popek, K.1
  • 71
    • 0032232875 scopus 로고    scopus 로고
    • Post-traumatic epilepsy: retrospective analysis of 90 severe traumatic brain injuries
    • Epilepsie post-traumatique: analyse retrospective d'une serie de 90 traumatismes craniens graves
    • Richard I, Francois C, Louis F, de la Greve M, Perrouin-Verbe B, Mathe JF. Post-traumatic epilepsy: retrospective analysis of 90 severe traumatic brain injuries [Epilepsie post-traumatique: analyse retrospective d'une serie de 90 traumatismes craniens graves]. Annales de Readaptation et de Medecine Physique 1998;41(7):409-15.
    • (1998) Annales de Readaptation et de Medecine Physique , vol.41 , Issue.7 , pp. 409-415
    • Richard, I.1    Francois, C.2    Louis, F.3    de la Greve, M.4    Perrouin-Verbe, B.5    Mathe, J.F.6
  • 73
    • 0019488650 scopus 로고
    • Prophylactive treatment of post traumatic epilepsy: results of a long-term follow-up in Czechoslovakia
    • Servit Z, Musil F. Prophylactive treatment of post traumatic epilepsy: results of a long-term follow-up in Czechoslovakia. Epilepsia 1981;22(3):315-20.
    • (1981) Epilepsia , vol.22 , Issue.3 , pp. 315-320
    • Servit, Z.1    Musil, F.2
  • 74
    • 0028336933 scopus 로고
    • Neurobehavioral effects of phenytoin and carbamazepine in patients recovering from brain trauma: a comparative study
    • Smith KR Jr, Goulding PM, Wilderman D, Goldfader PR, Holterman-Hommes P, Wei F. Neurobehavioral effects of phenytoin and carbamazepine in patients recovering from brain trauma: a comparative study. Archives of Neurology 1994;51(7):653-60.
    • (1994) Archives of Neurology , vol.51 , Issue.7 , pp. 653-660
    • Smith, K.R.1    Goulding, P.M.2    Wilderman, D.3    Goldfader, P.R.4    Holterman-Hommes, P.5    Wei, F.6
  • 75
    • 84858281856 scopus 로고    scopus 로고
    • Initial EEG predicts outcomes in a trial of levetiracetam vs. fosphenytoin for seizure prevention
    • Steinbaugh LA, Lindsell CJ, Shutter LA, Szaflarski JP. Initial EEG predicts outcomes in a trial of levetiracetam vs. fosphenytoin for seizure prevention. Epilepsy & Behavior 2012;23:280-4.
    • (2012) Epilepsy & Behavior , vol.23 , pp. 280-284
    • Steinbaugh, L.A.1    Lindsell, C.J.2    Shutter, L.A.3    Szaflarski, J.P.4
  • 77
    • 0142136046 scopus 로고    scopus 로고
    • Risk factors for posttraumatic seizures in adults
    • Temkin NR. Risk factors for posttraumatic seizures in adults. Epilepsia 2003;44(Suppl s10):18-20.
    • (2003) Epilepsia , vol.44 , pp. 18-20
    • Temkin, N.R.1
  • 78
    • 77950594511 scopus 로고    scopus 로고
    • Post-traumatic seizures -a prospective study from a tertiary level trauma center in a developing country
    • Thapa A, Chandra SP, Sinha S, Sreenivas V, Sharma BS, Tripathi M. Post-traumatic seizures -a prospective study from a tertiary level trauma center in a developing country. Seizure 2010;19(4):211-6.
    • (2010) Seizure , vol.19 , Issue.4 , pp. 211-216
    • Thapa, A.1    Chandra, S.P.2    Sinha, S.3    Sreenivas, V.4    Sharma, B.S.5    Tripathi, M.6
  • 79
    • 85041731197 scopus 로고    scopus 로고
    • Prophylaxis or therapy for patients with open cranio-cerebral trauma in order to prevent post-traumatic epilepsy
    • Tomovic M, Ilic T, Mihajlovic M, Minic LJ, Jovicic A. Prophylaxis or therapy for patients with open cranio-cerebral trauma in order to prevent post-traumatic epilepsy. Journal of the Neurological Sciences 1997;150(Suppl 1):S214, Abstract no: 4-06-07.
    • (1997) Journal of the Neurological Sciences , vol.150 , pp. S214
    • Tomovic, M.1    Ilic, T.2    Mihajlovic, M.3    Minic, L.J.4    Jovicic, A.5
  • 80
    • 17644386216 scopus 로고    scopus 로고
    • Insulin therapy protects the central and peripheral nervous system of intensive care patients
    • PUBMED: 15851721]
    • Van den Berghe G, Schoonheydt K, Becx P, Bruyninckx F, Wouters PJ. Insulin therapy protects the central and peripheral nervous system of intensive care patients. Neurology 2005;64(8):1348-53. [PUBMED: 15851721]
    • (2005) Neurology , vol.64 , Issue.8 , pp. 1348-1353
    • Van den Berghe, G.1    Schoonheydt, K.2    Becx, P.3    Bruyninckx, F.4    Wouters, P.J.5
  • 81
    • 85027905294 scopus 로고    scopus 로고
    • Retrospective analysis of phenytoin and levetiracetam for seizure prophylaxis after traumatic brain injury
    • Virant-Young D, Alexander R, Umstead G, Savoy-Moore R, Himes D, Nikolavsky M, et al. Retrospective analysis of phenytoin and levetiracetam for seizure prophylaxis after traumatic brain injury. Critical Care Medicine 2009;37(12 suppl):A443, Abstract no: 904.
    • (2009) Critical Care Medicine , vol.37 , Issue.12 , pp. A443
    • Virant-Young, D.1    Alexander, R.2    Umstead, G.3    Savoy-Moore, R.4    Himes, D.5    Nikolavsky, M.6
  • 82
    • 3042685693 scopus 로고    scopus 로고
    • Does glucocorticoid administration prevent late seizures after head injury?
    • Watson NF, Barber JK, Doherty MJ, Miller JW, Temkin NR. Does glucocorticoid administration prevent late seizures after head injury?. Epilepsia 2004;45(6):690-4.
    • (2004) Epilepsia , vol.45 , Issue.6 , pp. 690-694
    • Watson, N.F.1    Barber, J.K.2    Doherty, M.J.3    Miller, J.W.4    Temkin, N.R.5
  • 83
    • 0018533598 scopus 로고
    • Prophylactic phenytoin in severe head injuries
    • [PUBMED: 113510]
    • Wohns RNW, Wyler AR. Prophylactic phenytoin in severe head injuries. Journal of Neurosurgery 1979;51(4):507-9. [PUBMED: 113510]
    • (1979) Journal of Neurosurgery , vol.51 , Issue.4 , pp. 507-509
    • Wohns, R.N.W.1    Wyler, A.R.2
  • 84
    • 0021813621 scopus 로고
    • A comparative study of laboratory parameters in head-injured patients receiving either phenytoin or placebo for 24 months
    • Bertch KE, Norton JA, Young AB, Rapp RP, Tibbs PA. A comparative study of laboratory parameters in head-injured patients receiving either phenytoin or placebo for 24 months. Drug Intelligence & Clinical Pharmacy 1985;19(7-8):561-6.
    • (1985) Drug Intelligence & Clinical Pharmacy , vol.19 , Issue.7-8 , pp. 561-566
    • Bertch, K.E.1    Norton, J.A.2    Young, A.B.3    Rapp, R.P.4    Tibbs, P.A.5
  • 85
    • 0020516427 scopus 로고
    • Cutaneous reactions in head-injured patients receiving phenytoin for seizure prophylaxis
    • Rapp RP, Norton JA, Young B, Tibbs PA. Cutaneous reactions in head-injured patients receiving phenytoin for seizure prophylaxis. Neurosurgery 1983;13(3):272-5.
    • (1983) Neurosurgery , vol.13 , Issue.3 , pp. 272-275
    • Rapp, R.P.1    Norton, J.A.2    Young, B.3    Tibbs, P.A.4
  • 86
    • 85041745273 scopus 로고    scopus 로고
    • Use of Biperiden for the Prevention of Post-Traumatic Epilepsy
    • Use of Biperiden for the Prevention of Post-Traumatic Epilepsy. Ongoing study 2013.
    • (2013) Ongoing study
  • 87
    • 85041718703 scopus 로고    scopus 로고
    • Allopregnanolone for the Treatment of Traumatic Brain Injury
    • Allopregnanolone for the Treatment of Traumatic Brain Injury. Ongoing study 2013.
    • (2013) Ongoing study
  • 88
    • 85041712991 scopus 로고    scopus 로고
    • Traumatic neuroprotection and epilepsy prevention of Valproate acid
    • Traumatic neuroprotection and epilepsy prevention of Valproate acid. Ongoing study 2013.
    • (2013) Ongoing study
  • 90
    • 0142136042 scopus 로고    scopus 로고
    • Overview of studies to prevent post traumatic epilepsy
    • Beghi E. Overview of studies to prevent post traumatic epilepsy. Epilepsia 2003;44(Suppl 10):21-6.
    • (2003) Epilepsia , vol.44 , pp. 21-26
    • Beghi, E.1
  • 91
    • 0021813621 scopus 로고
    • A comparative study of laboratory parameters in head-injured patients receiving either phenytoin or placebo for 24 months
    • Bertch KE, Norton JA, Young AB, Rapp RP, Tibbs PA. A comparative study of laboratory parameters in head-injured patients receiving either phenytoin or placebo for 24 months. Drug Intelligence & Clinical Pharmacy 1985;19(7-8):561-6.
    • (1985) Drug Intelligence & Clinical Pharmacy , vol.19 , Issue.7-8 , pp. 561-566
    • Bertch, K.E.1    Norton, J.A.2    Young, A.B.3    Rapp, R.P.4    Tibbs, P.A.5
  • 92
    • 33750904279 scopus 로고    scopus 로고
    • Effects of the novel antiepileptic drug lacosamide on the development of amygdala kindling in rats
    • Brandt C, Heile A, Potschka H, Stoehr T, Loscher W. Effects of the novel antiepileptic drug lacosamide on the development of amygdala kindling in rats. Epilepsia 2006;47(11):1803-9.
    • (2006) Epilepsia , vol.47 , Issue.11 , pp. 1803-1809
    • Brandt, C.1    Heile, A.2    Potschka, H.3    Stoehr, T.4    Loscher, W.5
  • 96
    • 77949680683 scopus 로고    scopus 로고
    • The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews
    • Kirkham JJ, Dwan KM, Altman DG, Gamble C, Dodd S, Smyth R, et al. The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews. BMJ 2010;340:c365. [DOI: http://dx.doi.org/10.1136/bmj.c365]
    • (2010) BMJ , vol.340
    • Kirkham, J.J.1    Dwan, K.M.2    Altman, D.G.3    Gamble, C.4    Dodd, S.5    Smyth, R.6
  • 97
    • 84883710616 scopus 로고    scopus 로고
    • Searching for studies
    • Higgins JPT, Green S (editors), Version 5.1.0 [updated March 2011]. The Cochrane Collaboration
    • Lefebvre C, Manheimer E, Glanville J. Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
    • (2011) Cochrane Handbook for Systematic Reviews of Interventions
    • Lefebvre, C.1    Manheimer, E.2    Glanville, J.3
  • 98
    • 0036347772 scopus 로고    scopus 로고
    • Animal models of epilepsy for the development of antiepileptogenic and disease-modifying drugs. A comparison of the pharmacology of kindling and post-status epilepticus models of temporal lobe epilepsy
    • [PUBMED: 12151122]
    • Löscher W. Animal models of epilepsy for the development of antiepileptogenic and disease-modifying drugs. A comparison of the pharmacology of kindling and post-status epilepticus models of temporal lobe epilepsy. Epilepsy Research 2002;50(1-2):105-23. [PUBMED: 12151122]
    • (2002) Epilepsy Research , vol.50 , Issue.1-2 , pp. 105-123
    • Löscher, W.1
  • 99
    • 0032583387 scopus 로고    scopus 로고
    • Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
    • Parmar MK, Torri V, Stewart L. Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Statistics in Medicine 1998;17(24):2815-34.
    • (1998) Statistics in Medicine , vol.17 , Issue.24 , pp. 2815-2834
    • Parmar, M.K.1    Torri, V.2    Stewart, L.3
  • 100
    • 79960705415 scopus 로고    scopus 로고
    • Review Manager (RevMan)
    • 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration,
    • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2012.
    • (2012)
  • 102
    • 39449083733 scopus 로고    scopus 로고
    • Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging
    • Slemmer JE, Shacka JJ, Sweeney MI, Weber JT. Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging. Current Medicinal Chemistry 2008;15(4):404-14.
    • (2008) Current Medicinal Chemistry , vol.15 , Issue.4 , pp. 404-414
    • Slemmer, J.E.1    Shacka, J.J.2    Sweeney, M.I.3    Weber, J.T.4
  • 103
    • 33947430454 scopus 로고    scopus 로고
    • A systematic review of rehabilitation of moderate to severe acquired brain injuries
    • Teasell R, Bayona N, Marshall S, Cullen N, Bayley M, Chundamala J, et al. A systematic review of rehabilitation of moderate to severe acquired brain injuries. Brain Injury 2007;21(2):107-12.
    • (2007) Brain Injury , vol.21 , Issue.2 , pp. 107-112
    • Teasell, R.1    Bayona, N.2    Marshall, S.3    Cullen, N.4    Bayley, M.5    Chundamala, J.6
  • 104
    • 0035048478 scopus 로고    scopus 로고
    • Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials
    • Temkin N. Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials. Epilepsia 2001;42(4):515-24.
    • (2001) Epilepsia , vol.42 , Issue.4 , pp. 515-524
    • Temkin, N.1
  • 105
    • 58849130137 scopus 로고    scopus 로고
    • Preventing and treating posttraumatic seizures: the human experience
    • Temkin N. Preventing and treating posttraumatic seizures: the human experience. Epilepsia 2009;50(Suppl 2):10-13.
    • (2009) Epilepsia , vol.50 , pp. 10-13
    • Temkin, N.1
  • 106
    • 0026009636 scopus 로고
    • A general parametric approach to the meta-analysis of randomised clinical trials
    • Whitehead A, Whitehead J. A general parametric approach to the meta-analysis of randomised clinical trials. Statistics in Medicine 1991;10(11):1665-77.
    • (1991) Statistics in Medicine , vol.10 , Issue.11 , pp. 1665-1677
    • Whitehead, A.1    Whitehead, J.2
  • 108
    • 62349094504 scopus 로고    scopus 로고
    • Posttraumatic epilepsy: hemorrhage, free radicals and the molecular regulation of glutamate
    • Willmore LJ, Ueda Y. Posttraumatic epilepsy: hemorrhage, free radicals and the molecular regulation of glutamate. Neurochemical Research 2009;34(4):688-97.
    • (2009) Neurochemical Research , vol.34 , Issue.4 , pp. 688-697
    • Willmore, L.J.1    Ueda, Y.2
  • 109
    • 0003782850 scopus 로고    scopus 로고
    • 5th Edition. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins,
    • Wyllie E. Wyllie's Treatment of Epilepsy. 5th Edition. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins, 2010.
    • (2010) Wyllie's Treatment of Epilepsy
    • Wyllie, E.1
  • 111
    • 84921430243 scopus 로고    scopus 로고
    • Anti-epileptic drugs for preventing seizures following acute traumatic brain injury
    • Schierhout G, Roberts IG. Anti-epileptic drugs for preventing seizures following acute traumatic brain injury. Cochrane Database of Systematic Reviews 2001, Issue 4. [DOI: 10.1002/14651858.CD000173]
    • (2001) Cochrane Database of Systematic Reviews , Issue.4
    • Schierhout, G.1    Roberts, I.G.2
  • 112


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.