Disruption of desmin-mitochondrial architecture in patients with regurgitant mitral valves and preserved ventricular function

Journal of Thoracic and Cardiovascular Surgery

Volumn 152, Issue 4, 2016, Pages 1059-1070.e2

  Ahmed, Mustafa I ^a   Guichard, Jason L ^a   Rajasekaran, Namakkal S ^b   Ahmad, Shama ^c   Mariappan, Nithya ^c   Litovsky, Silvio ^b   Gupta, Himanshu ^a,g   Lloyd, Steven G ^a,g   Denney, Thomas S ^h   Powell, Pamela Cox ^g   Aban, Inmaculada ^d   Collawn, James F ^e   Davies, James E ^f,g   McGiffin, David C ⁱ   Dell'Italia, Louis J ^a,g  

^a University of Alabama at Birmingham and Birmingham Veterans Affairs Medical Center   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^f University of Alabama at Birmingham   (United States)

^g BIRMINGHAM VA MEDICAL CENTER   (United States)

^h AUBURN UNIVERSITY   (United States)

ⁱ MONASH UNIVERSITY   (Australia)

Author keywords

cardiomyocyte; heart failure; mitochondria; mitral regurgitation

Indexed keywords

4 HYDROXYNONENAL; ALPHA CRYSTALLIN; DESMIN; INTERMEDIATE FILAMENT PROTEIN; VOLTAGE DEPENDENT ANION CHANNEL; 4-HYDROXY-2-NONENAL; ALDEHYDE; CRYAB PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; AUTOPSY; CARDIAC MUSCLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE MICROSCOPY; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART VENTRICLE FUNCTION; HUMAN; IMMUNOGOLD ELECTRON MICROSCOPY; MAJOR CLINICAL STUDY; MALE; MEDICAL SOCIETY; MITRAL VALVE REGURGITATION; MITRAL VALVE REPAIR; MITRAL VALVE SURGERY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN AGGREGATION; SARCOMERE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; CARDIAC MUSCLE CELL; HEART LEFT VENTRICLE FUNCTION; HEART MITOCHONDRION; METABOLISM; MIDDLE AGED; TREATMENT OUTCOME; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ALDEHYDES; ALPHA-CRYSTALLIN B CHAIN; DESMIN; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MITOCHONDRIA, HEART; MITRAL VALVE INSUFFICIENCY; MYOCYTES, CARDIAC; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT; VOLTAGE-DEPENDENT ANION CHANNELS;

EID: 84991112180     PISSN: 00225223     EISSN: 1097685X     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2016.06.017     Document Type: Article

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