A randomized controlled phase IIb trial of Beta 1-receptor blockade for chronic degenerative mitral regurgitation

Journal of the American College of Cardiology

Volumn 60, Issue 9, 2012, Pages 833-838

  Ahmed, Mustafa I ^a   Aban, Inmaculada ^b   Lloyd, Steven G ^a,c   Gupta, Himanshu ^a,c   Howard, George ^b   Inusah, Seidu ^b   Peri, Kalyani ^b   Robinson, Jessica ^a   Smith, Patty ^a   McGiffin, David C ^b   Schiros, Chun G ^d   Denney Jr , Thomas ^d   Dell'Italia, Louis J ^a,c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c BIRMINGHAM VA MEDICAL CENTER   (United States)

^d AUBURN UNIVERSITY   (United States)

Author keywords

beta blockade; medical therapy; mitral regurgitation; mitral valve disease

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; METOPROLOL SUCCINATE; PLACEBO;

ADULT; AGED; ARTICLE; BODY SURFACE; CARDIOVASCULAR PARAMETERS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG DOSE TITRATION; FEMALE; FOLLOW UP; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART LEFT VENTRICLE FILLING; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE LONGITUDINAL STRAIN RATE; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; HUMAN; INTENTION TO TREAT ANALYSIS; MALE; MITRAL VALVE REGURGITATION; MITRAL VALVE REPAIR; MITRAL VALVE REPLACEMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECEPTOR BLOCKING; SENSITIVITY ANALYSIS; THREE DIMENSIONAL IMAGING; TREATMENT DURATION; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT;

ADRENERGIC BETA-ANTAGONISTS; ADULT; AGED; CASE-CONTROL STUDIES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; METOPROLOL; MIDDLE AGED; MITRAL VALVE INSUFFICIENCY; TREATMENT OUTCOME; VENTRICULAR REMODELING;

EID: 84865302439     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2012.04.029     Document Type: Article

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