Topiramate increases the rewarding properties of cocaine in young-adult mice limiting its clinical usefulness

Psychopharmacology

Volumn 233, Issue 23-24, 2016, Pages 3849-3859

  Arenas, M C ^a   Mateos Garcia A ^a   Manzanedo, C ^a   Rodriguez Arias M ^a,b   Aguilar, M A ^a,b   Navarrete, F ^b,c   Gutiérrez, M S García ^b,c   Manzanares, J ^b,c   Minarro J ^a,b  

^a UNIVERSITY OF VALENCIA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

Author keywords

Cocaine; CPP; Mice; Reward effects; Topiramate; Ventral tegmental area

Indexed keywords

COCAINE; DOPAMINE TRANSPORTER; TOPIRAMATE; TYROSINE 3 MONOOXYGENASE; ANTICONVULSIVE AGENT; DOPAMINE UPTAKE INHIBITOR; FRUCTOSE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; DAT GENE; DOPAMINERGIC ACTIVITY; DRUG EFFECT; DRUG EFFICACY; DRUG SCREENING; DRUG USE; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; REINFORCEMENT; REWARD; TH GENE; VENTRAL TEGMENTUM; YOUNG ADULT; ANALOGS AND DERIVATIVES; ANALYSIS OF VARIANCE; ANIMAL; DISEASE MODEL; DRUG EFFECTS;

ANALYSIS OF VARIANCE; ANIMALS; ANTICONVULSANTS; COCAINE; COCAINE-RELATED DISORDERS; DISEASE MODELS, ANIMAL; DOPAMINE UPTAKE INHIBITORS; FRUCTOSE; MALE; MICE; REWARD; VENTRAL TEGMENTAL AREA;

EID: 84991094787     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-016-4409-4     Document Type: Article

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