A double-blind, placebo-controlled trial of topiramate for the treatment of comorbid cocaine and alcohol dependence

Drug and Alcohol Dependence

Volumn 133, Issue 1, 2013, Pages 94-99

  Kampman, Kyle M ^a   Pettinati, Helen M ^a   Lynch, Kevin G ^a   Spratt, Kelly ^b   Wierzbicki, Michael R ^a   O'Brien, Charles P ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Alcohol; Clinical trial; Cocaine; Placebo; Topiramate

Indexed keywords

PLACEBO; TOPIRAMATE;

ADDICTION SEVERITY INDEX; ADULT; AGED; ALCOHOL WITHDRAWAL; ALCOHOLISM; ARTICLE; CLINICAL GLOBAL IMPRESSION SCALE; COCAINE DEPENDENCE; COGNITIVE THERAPY; COMORBIDITY; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG DOSE TITRATION; DRUG SCREENING; DRUG WITHDRAWAL; FEMALE; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; PARESTHESIA; PATIENT COMPLIANCE; PRIORITY JOURNAL; PSYCHOTHERAPY; RANDOMIZED CONTROLLED TRIAL; SEDATION; SELF REPORT; SIDE EFFECT; STRUCTURED CLINICAL INTERVIEW FOR DSM DISORDERS; TREATMENT OUTCOME; URINALYSIS; WITHDRAWAL SYNDROME; XEROSTOMIA;

ALCOHOL; CLINICAL TRIAL; COCAINE; PLACEBO; TOPIRAMATE;

ADOLESCENT; ADULT; AGED; ALCOHOLISM; ANTICONVULSANTS; BEHAVIOR, ADDICTIVE; COCAINE-RELATED DISORDERS; COGNITIVE THERAPY; COMBINED MODALITY THERAPY; DOUBLE-BLIND METHOD; FEMALE; FRUCTOSE; HUMANS; MALE; MIDDLE AGED; PATIENT COMPLIANCE; RECURRENCE; SEVERITY OF ILLNESS INDEX; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84884417951     PISSN: 03768716     EISSN: 18790046     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2013.05.026     Document Type: Article

References (35)

1. Brady K.T., Sonne S., Randall C.L., Adinoff B., Malcolm R. Features of cocaine dependence with concurrent alcohol abuse. Drug Alcohol Depend. 1995, 39:69-71.
2. Carroll K.M., Rounsaville B.J., Bryant K.J. Alcoholism in treatment-seeking cocaine abusers: clinical and prognostic significance. J. Stud. Alcohol 1993, 54:199-208.
3. Cornish J.L., Kalivas P.W. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. J. Neurosci. 2000, 20:RC89.
4. Diggle P., Heagerty P., Liang K., Zeger S. Analysis of Longitudinal Data 2002, Oxford University Press, Oxford.
5. Elkashef A., Kahn R., Yu E., Iturriaga E., Li S.H., Anderson A., Chiang N., Ait-Daoud N., Weiss D., McSherry F., Serpi T., Rawson R., Hrymoc M., Weis D., McCann M., Pham T., Stock C., Dickinson R., Campbell J., Gorodetzky C., Haning W., Carlton B., Mawhinney J., Li M.D., Johnson B.A., Elkashef A., Kahn R., Yu E., Iturriaga E., Li S.-H., Anderson A., Chiang N., Ait-Daoud N., Weiss D., McSherry F., Serpi T., Rawson R., Hrymoc M., Weis D., McCann M., Pham T., Stock C., Dickinson R., Campbell J., Gorodetzky C., Haning W., Carlton B., Mawhinney J., Li M.D., Johnson B.A. Topiramate for the treatment of methamphetamine addiction: a multi-center placebo-controlled trial. Addiction 2012, 107:1297-1306.
6. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured Clinical Interview for DSM-IV Axis I Disorders - Patient Edition (SCID-IP, Version 2.0). 1996, Biometrics Research Department, New York State Psychiatric Institute, New York.
7. Flannery B.A., Volpicelli J.R., Pettinati H.M. Psychometric properties of the Penn Alcohol Craving Scale. Alcohol. Clin. Exp. Res. 1999, 23:1289-1295.
8. Gibbs J.W., Sombati S., DeLorenzo R.J., Coulter D.A. Cellular actions of topiramate: blockade of kainate-evoked inward currents in cultured hippocampal neurons. Epilepsia 2000, 41(Suppl. 1):S10-S16.
9. Assessment Manual for Psychopharmacology: Publication ADM 76-338. 1976, US Department of Health Education and Welfare, Washington, DC. W. Guy (Ed.).
10. Halikas J.A., Kuhn K.L., Crosby R., Carlson G., Crea F. The measurement of craving in cocaine patients using the Minnesota Cocaine Craving Scale. Comp. Psychiatry 1991, 32:22-27.
11. Heil S.H., Badger G.J., Higgins S.T. Alcohol dependence among cocaine-dependent outpatients: demographics, drug use, treatment outcome and other characteristics. J. Stud. Alcohol 2001, 62:14-22.
12. Johnson B.A., Ait-Daoud N., Bowden C.L., DiClemente C.C., Roache J.D., Lawson K., Javors M.A., Ma J.Z., Johnson B.A., Ait-Daoud N., Bowden C.L., DiClemente C.C., Roache J.D., Lawson K., Javors M.A., Ma J.Z. Oral topiramate for treatment of alcohol dependence: a randomised controlled trial. Lancet 2003, 361:1677-1685.
13. Johnson B.A., Roache J.D., Ait-Daoud N., Gunderson E.W., Haughey H.M., Wang X., Liu L. Topiramate's effects on cocaine-induced subjective mood, craving and preference for money over drug taking. Addict. Biol. 2012, 18:405-416.
14. Johnson B.A., Rosenthal N., Capece J.A., Wiegand F., Mao L., Beyers K., McKay A., Ait-Daoud N., Anton R.F., Ciraulo D.A., Kranzler H.R., Mann K., O'Malley S.S., Swift R.M., Topiramate for Alcoholism Advisory B., Topiramate for Alcoholism Study G. Topiramate for treating alcohol dependence: a randomized controlled trial. JAMA 2007, 298:1641-1651.
15. Johnson B.A., Rosenthal N., Capece J.A., Wiegand F., Mao L., Beyers K., McKay A., Ait-Daoud N., Anton R.F., Ciraulo D.A., Kranzler H.R., Mann K., O'Malley S.S., Swift R.M., Topiramate for Alcoholism Advisory B., Topiramate for Alcoholism Study G., Johnson B.A., Rosenthal N., Capece J.A., Wiegand F., Mao L., Beyers K., McKay A., Ait-Daoud N., Anton R.F., Ciraulo D.A., Kranzler H.R., Mann K., O'Malley S.S., Swift R.M. Topiramate for treating alcohol dependence: a randomized controlled trial. JAMA 2007, 298:1641-1651.
16. Kadden R., Carroll K.M., Donovan D., Cooney N., Monti P., Abrams D., Litt M., Hester R. Cognitive Behavioral Coping Skills Manual 1992, U.S. Governmmet Printing Office, Washington, DC.
17. Kampman K.M., Pettinati H., Lynch K.G., Dackis C., Sparkman T., Weigley C., O'Brien C.P., Kampman K.M., Pettinati H., Lynch K.G., Dackis C., Sparkman T., Weigley C., O'Brien C.P. A pilot trial of topiramate for the treatment of cocaine dependence. Drug Alcohol Depend. 2004, 75:233-240.
18. Kampman K.M., Volpicelli J.R., McGinnis D.E., Alterman A.I., Weinieb R.M., D'Angelo L.D., Epperson L. Reliability and validity of the cocaine selective severity assessment. Addict. Behav. 1998, 23:49-461.
19. Kuzniecky R., Hetherington H., Ho S., Pan J., Martin R., Gilliam F., Hugg J., Faught E. Topiramate increases cerebral GABA in healthy humans. Neurology 1998, 51:627-629.
20. Litten R.Z., Fertig J.B., Falk D.E., Ryan M.L., Mattson M.E., Collins J.F., Murtaugh C., Ciraulo D., Green A.I., Johnson B., Pettinati H., Swift R., Afshar M., Brunette M.F., Tiouririne N.A.D., Kampman K., Stout R., Group N.S. A double-blind, placebo-controlled trial to assess the efficacy of quetiapine fumarate XR in very heavy-drinking alcohol-dependent patients. Alcohol. Clin. Exp. Res. 2012, 36:406-416.
21. Mariani J.J., Pavlicova M., Bisaga A., Nunes E.V., Brooks D.J., Levin F.R. Extended-release mixed amphetamine salts and topiramate for cocaine dependence: a randomized controlled trial. Biol. Psychiatry 2012, 72:950-956.
22. McCance-Katz E.F., Price L.H., McDougle C.J., Kosten T.R., Black J.E., Jatlow P.I. Concurrent cocaine-ethanol ingestion in humans: pharmacology, physiology, behavior, and the role of cocaethylene. Psychopharmacology (Berl.) 1993, 111:39-46.
23. McLellan A.T., Kushner H., Metzger D., Peters R., Smith I., Grissom G., Pettinati H., Argeriou M. The fifth edition of the Addiction Severity Index. J. Subst. Abuse Treat. 1992, 9:199-213.
24. Molenberghs G., Verbeke G. Models for Discrete Longitudinal Data 2005, Springer, New York.
25. Newton T.F., Kalechstein A.D., Tervo K.E., Ling W., Newton T.F., Kalechstein A.D., Tervo K.E., Ling W. Irritability following abstinence from cocaine predicts euphoric effects of cocaine administration. Addict. Behav. 2003, 28:817-821.
26. Petroff O.A., Hyder F., Mattson R.H., Rothman D.L. Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy. Neurology 1999, 52:473-478.
27. Regier D.A., Farmer M.E., Rae D.S., Locke B.Z., Keith S.J., Judd L.L., Goodwin F.K. Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) study. JAMA 1990, 264:2511-2518.
28. Sheehan D.V., Lecrubier Y., Sheehan K.H., Amorim P., Janavs J., Weiller E., Hergueta T., Baker R., Dunbar G.C. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 1998, 59(Suppl. 20):22-33. (quiz 34-57).
29. Sobell L.C., Sobell M.B. Alcohol Timeline Followback Users' Manual 1995, Addiction Research Foundation, Toronto.
30. Sofuoglu M., Dudish-Poulsen S., Brown S.B., Hatsukami D.K., Sofuoglu M., Dudish-Poulsen S., Brown S.B., Hatsukami D.K. Association of cocaine withdrawal symptoms with more severe dependence and enhanced subjective response to cocaine. Drug Alcohol Depend. 2003, 69:273-282.
31. Sullivan J.T., Sykora K., Schneiderman J., Naranjo C.A., Sellers E. Assessment of alcohol withdrawal: the revised clinical instiute withdrawal assessment for alcohol scale. Br. J. Addict. 1989, 84:1353-1357.
32. Uslaner J., Kalechstein A., Richter T., Ling W., Newton T. Association of depressive symptoms during abstinence with the subjective high produced by cocaine. Am. J. Psychiatry 1999, 156:1444-1446.
33. Wallace B.C. Psychological and environmental determinants of relapse in crack cocaine smokers. J. Subst. Abuse Treat. 1989, 6:95-106.
34. Walsh D.C., Hingson R.W., Merrigan D.M., Cupples L.A., Levenson S.M., Coffman G.A. Associations between alcohol and cocaine use in a sample of problem-drinking employees. J. Stud. Alcohol 1991, 52:17-25.
35. White H.S., Brown S.D., Woodhead J.H., Skeen G.A., Wolf H.H. Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold. Epilepsy Res. 1997, 28:167-179.