메뉴 건너뛰기




Volumn 5, Issue 10, 2016, Pages

Therapeutic CD94/NKG2A blockade improves natural killer cell dysfunction in chronic lymphocytic leukemia

Author keywords

Chronic lymphocytic leukemia; natural killer cells

Indexed keywords

AF 1330 SP; CD94 ANTIGEN; HLA E ANTIGEN; MAB 1257 SP; MONALIZUMAB; MONOCLONAL ANTIBODY; NATURAL KILLER CELL RECEPTOR NKG2A; UNCLASSIFIED DRUG;

EID: 84990913687     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2016.1226720     Document Type: Article
Times cited : (116)

References (32)
  • 1
    • 84954400636 scopus 로고    scopus 로고
    • Cancer statistics, 2016
    • 26742998
    • R.L.Siegel, K.D.Miller, A.Jemal. Cancer statistics, 2016. CA 2016; 66:7-30; PMID:26742998; http://dx.doi.org/10.3322/caac.21332
    • (2016) CA , vol.66 , pp. 7-30
    • Siegel, R.L.1    Miller, K.D.2    Jemal, A.3
  • 2
    • 84918536030 scopus 로고    scopus 로고
    • New strategies in chronic lymphocytic leukemia: shifting treatment paradigms
    • 25294898
    • F.T.Awan, J.C.Byrd. New strategies in chronic lymphocytic leukemia:shifting treatment paradigms. Clin Cancer Res 2014; 20:5869-74; PMID:25294898; http://dx.doi.org/10.1158/1078-0432.CCR-14-1889
    • (2014) Clin Cancer Res , vol.20 , pp. 5869-5874
    • Awan, F.T.1    Byrd, J.C.2
  • 3
    • 43449101911 scopus 로고    scopus 로고
    • Prognostic importance of T and NK-cells in a consecutive series of newly diagnosed patients with chronic lymphocytic leukaemia
    • 18384436
    • S.Palmer, C.A.Hanson, C.S.Zent, L.F.Porrata, B.Laplant, S.M.Geyer, S.N.Markovic, T.G.Call, D.A.Bowen, D.F.Jelinek et al. Prognostic importance of T and NK-cells in a consecutive series of newly diagnosed patients with chronic lymphocytic leukaemia. Br J Haematol 2008; 141:607-14; PMID:18384436; http://dx.doi.org/10.1111/j.1365-2141.2008.07070.x
    • (2008) Br J Haematol , vol.141 , pp. 607-614
    • Palmer, S.1    Hanson, C.A.2    Zent, C.S.3    Porrata, L.F.4    Laplant, B.5    Geyer, S.M.6    Markovic, S.N.7    Call, T.G.8    Bowen, D.A.9    Jelinek, D.F.10
  • 4
    • 84861480726 scopus 로고    scopus 로고
    • Primary B-CLL resistance to NK cell cytotoxicity can be overcome in vitro and in vivo by priming NK cells and monoclonal antibody therapy
    • 22318393
    • C.Veuillen, T.Aurran-Schleinitz, R.Castellano, J.Rey, F.Mallet, F.Orlanducci, L.Pouyet, S.Just-Landi, D.Coso, V.Ivanov et al. Primary B-CLL resistance to NK cell cytotoxicity can be overcome in vitro and in vivo by priming NK cells and monoclonal antibody therapy. J Clin Immunol 2012; 32:632-46; PMID:22318393; http://dx.doi.org/10.1007/s10875-011-9624-5
    • (2012) J Clin Immunol , vol.32 , pp. 632-646
    • Veuillen, C.1    Aurran-Schleinitz, T.2    Castellano, R.3    Rey, J.4    Mallet, F.5    Orlanducci, F.6    Pouyet, L.7    Just-Landi, S.8    Coso, D.9    Ivanov, V.10
  • 5
    • 10944235504 scopus 로고    scopus 로고
    • Activating CD94:NKG2C and inhibitory CD94:NKG2A receptors are expressed by distinct subsets of committed CD8+ TCR αβ lymphocytes
    • 15517612
    • L.Arlettaz, J.Villard, C.de Rham, S.Degermann, B.Chapuis, B.Huard, E.Roosnek. Activating CD94:NKG2C and inhibitory CD94:NKG2A receptors are expressed by distinct subsets of committed CD8+ TCR αβ lymphocytes. Eur J Immunol 2004; 34:3456-64; PMID:15517612; http://dx.doi.org/10.1002/eji.200425210
    • (2004) Eur J Immunol , vol.34 , pp. 3456-3464
    • Arlettaz, L.1    Villard, J.2    de Rham, C.3    Degermann, S.4    Chapuis, B.5    Huard, B.6    Roosnek, E.7
  • 7
    • 0034058876 scopus 로고    scopus 로고
    • Selective expansion of intraepithelial lymphocytes expressing the HLA-E-specific natural killer receptor CD94 in celiac disease
    • 10784586
    • B.Jabri, N.P.M.De Serre, C.Cellier, K.Evans, C.Gache, C.Carvalho, J.F.Mougenot, M.Allez et al. Selective expansion of intraepithelial lymphocytes expressing the HLA-E-specific natural killer receptor CD94 in celiac disease. Gastroenterology 2000; 118:867-79; PMID:10784586; http://dx.doi.org/10.1016/S0016-5085(00)70173-9
    • (2000) Gastroenterology , vol.118 , pp. 867-879
    • Jabri, B.1    De Serre, N.P.M.2    Cellier, C.3    Evans, K.4    Gache, C.5    Carvalho, C.6    Mougenot, J.F.7    Allez, M.8
  • 10
    • 0032473478 scopus 로고    scopus 로고
    • Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis
    • 9480992
    • F.Borrego, M.Ulbrecht, E.H.Weiss, J.E.Coligan, A.G.Brooks. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis. J Exp Med 1998; 187:813-8; PMID:9480992; http://dx.doi.org/10.1084/jem.187.5.813
    • (1998) J Exp Med , vol.187 , pp. 813-818
    • Borrego, F.1    Ulbrecht, M.2    Weiss, E.H.3    Coligan, J.E.4    Brooks, A.G.5
  • 12
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute–Working Group 1996 guidelines
    • 18216293
    • M.Hallek, B.D.Cheson, D.Catovsky, F.Caligaris-Cappio, G.Dighiero, H.Döhner, P.Hillmen, M.J.Keating, E.Montserrat, K.R.Rai et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia:a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute–Working Group 1996 guidelines. Blood 2008; 111:5446-56; PMID:18216293; http://dx.doi.org/10.1182/blood-2007-06-093906
    • (2008) Blood , vol.111 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3    Caligaris-Cappio, F.4    Dighiero, G.5    Döhner, H.6    Hillmen, P.7    Keating, M.J.8    Montserrat, E.9    Rai, K.R.10
  • 16
    • 84911415636 scopus 로고    scopus 로고
    • Clinical and immunological significance of HLA-E in stem cell transplantation and cancer
    • 25413103
    • L.Wieten, N.M.Mahaweni, C.E.M.Voorter, G.M.J.Bos, M.G.J.Tilanus. Clinical and immunological significance of HLA-E in stem cell transplantation and cancer. Tissue Antigens 2014; 84:523-35; PMID:25413103; http://dx.doi.org/10.1111/tan.12478
    • (2014) Tissue Antigens , vol.84 , pp. 523-535
    • Wieten, L.1    Mahaweni, N.M.2    Voorter, C.E.M.3    Bos, G.M.J.4    Tilanus, M.G.J.5
  • 17
    • 0029786305 scopus 로고    scopus 로고
    • Interferon-γ induction of the human leukocyte antigen-E gene is mediated through binding of a complex containing STAT1α to a distinct interferon-γ-responsive element
    • 8702722
    • K.S.Gustafson, G.D.Ginder. Interferon-γ induction of the human leukocyte antigen-E gene is mediated through binding of a complex containing STAT1α to a distinct interferon-γ-responsive element. J Biol Chem 1996; 271:20035-46; PMID:8702722; http://dx.doi.org/10.1074/jbc.271.33.20035
    • (1996) J Biol Chem , vol.271 , pp. 20035-20046
    • Gustafson, K.S.1    Ginder, G.D.2
  • 18
    • 13544263581 scopus 로고    scopus 로고
    • GATA-3 is an important transcription factor for regulating human NKG2A gene expression
    • 15699146
    • A.I.Marusina, D.-K.Kim, L.D.Lieto, F.Borrego, J.E.Coligan. GATA-3 is an important transcription factor for regulating human NKG2A gene expression. J Immunol 2005; 174:2152-9; PMID:15699146; http://dx.doi.org/10.4049/jimmunol.174.4.2152
    • (2005) J Immunol , vol.174 , pp. 2152-2159
    • Marusina, A.I.1    Kim, D.-K.2    Lieto, L.D.3    Borrego, F.4    Coligan, J.E.5
  • 19
    • 0019491440 scopus 로고
    • Deficiency of natural killer cell activity in patients with chronic lymphocytic leukemia
    • 6169660
    • H.-W.Ziegler, N.E.Kay, J.M.Zarling. Deficiency of natural killer cell activity in patients with chronic lymphocytic leukemia. Int J Cancer 1981; 27:321-7; PMID:6169660; http://dx.doi.org/10.1002/ijc.2910270310
    • (1981) Int J Cancer , vol.27 , pp. 321-327
    • Ziegler, H.-W.1    Kay, N.E.2    Zarling, J.M.3
  • 20
    • 0021336528 scopus 로고
    • Impaired natural killer activity in patients with chronic lymphocytic leukemia is associated with a deficiency of azurophilic cytoplasmic granules in putative NK cells
    • 6607080
    • N.E.Kay, J.M.Zarling. Impaired natural killer activity in patients with chronic lymphocytic leukemia is associated with a deficiency of azurophilic cytoplasmic granules in putative NK cells. Blood 1984; 63:305-9; PMID:6607080
    • (1984) Blood , vol.63 , pp. 305-309
    • Kay, N.E.1    Zarling, J.M.2
  • 21
    • 78149474940 scopus 로고    scopus 로고
    • The clinical application of monoclonal antibodies in chronic lymphocytic leukemia
    • 20610811
    • S.M.Jaglowski, L.Alinari, R.Lapalombella, N.Muthusamy, J.C.Byrd. The clinical application of monoclonal antibodies in chronic lymphocytic leukemia. Blood 2010; 116:3705-14; PMID:20610811; http://dx.doi.org/10.1182/blood-2010-04-001230
    • (2010) Blood , vol.116 , pp. 3705-3714
    • Jaglowski, S.M.1    Alinari, L.2    Lapalombella, R.3    Muthusamy, N.4    Byrd, J.C.5
  • 22
    • 84861480726 scopus 로고    scopus 로고
    • Primary B-CLL resistance to NK Cell cytotoxicity can be overcome in vitro and in vivo by priming NK cells and monoclonal antibody therapy
    • 22318393
    • C.Veuillen, T.Aurran-Schleinitz, R.Castellano, J.Rey, F.Mallet, F.Orlanducci, L.Pouyet, S.Just-Landi, D.Coso, V.Ivanov et al. Primary B-CLL resistance to NK Cell cytotoxicity can be overcome in vitro and in vivo by priming NK cells and monoclonal antibody therapy. J Clin Immunol 2012; 32:632-46; PMID:22318393; http://dx.doi.org/10.1007/s10875-011-9624-5
    • (2012) J Clin Immunol , vol.32 , pp. 632-646
    • Veuillen, C.1    Aurran-Schleinitz, T.2    Castellano, R.3    Rey, J.4    Mallet, F.5    Orlanducci, F.6    Pouyet, L.7    Just-Landi, S.8    Coso, D.9    Ivanov, V.10
  • 23
    • 20644439105 scopus 로고    scopus 로고
    • MHC class Ib molecules bridge innate and acquired immunity
    • 15928678
    • J.R.Rodgers, R.G.Cook. MHC class Ib molecules bridge innate and acquired immunity. Nat Rev Immunol 2005; 5:459-71; PMID:15928678; http://dx.doi.org/10.1038/nri1635
    • (2005) Nat Rev Immunol , vol.5 , pp. 459-471
    • Rodgers, J.R.1    Cook, R.G.2
  • 24
    • 0023762569 scopus 로고
    • HLA-E. A novel HLA class I gene expressed in resting T lymphocytes
    • 3260916
    • B.H.Koller, D.E.Geraghty, Y.Shimizu, R.DeMars, H.T.Orr. HLA-E. A novel HLA class I gene expressed in resting T lymphocytes. J Immunol 1988; 141:897-904; PMID:3260916
    • (1988) J Immunol , vol.141 , pp. 897-904
    • Koller, B.H.1    Geraghty, D.E.2    Shimizu, Y.3    DeMars, R.4    Orr, H.T.5
  • 25
    • 0027455756 scopus 로고
    • Interferon gamma inhibits apoptotic cell death in B cell chronic lymphocytic leukemia
    • 7678114
    • M.Buschle, D.Campana, S.R.Carding, C.Richard, A.V.Hoffbrand, M.K.Brenner. Interferon gamma inhibits apoptotic cell death in B cell chronic lymphocytic leukemia. J Exp Med 1993; 177:213-8; PMID:7678114; http://dx.doi.org/10.1084/jem.177.1.213
    • (1993) J Exp Med , vol.177 , pp. 213-218
    • Buschle, M.1    Campana, D.2    Carding, S.R.3    Richard, C.4    Hoffbrand, A.V.5    Brenner, M.K.6
  • 26
    • 0031960065 scopus 로고    scopus 로고
    • Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants
    • 9565368
    • M.Carretero, G.Palmieri, M.Llano, V.Tullio, A.Santoni, D.E.Geraghty, M.López-Botet. Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A:evidence for receptor function in heterologous transfectants. Eur J Immunol 1998; 28:1280-91; PMID:9565368; http://dx.doi.org/10.1002/(SICI)1521-4141(199804)28:04%3c1280::AID-IMMU1280%3e3.0.CO;2-O
    • (1998) Eur J Immunol , vol.28 , pp. 1280-1291
    • Carretero, M.1    Palmieri, G.2    Llano, M.3    Tullio, V.4    Santoni, A.5    Geraghty, D.E.6    López-Botet, M.7
  • 27
    • 0033564869 scopus 로고    scopus 로고
    • CD94/NKG2-A inhibitory complex blocks CD16-triggered Syk and extracellular regulated kinase activation, leading to cytotoxic function of human NK cells
    • 10358164
    • G.Palmieri, V.Tullio, A.Zingoni, M.Piccoli, L.Frati, M.Lopez-Botet, A.Santoni. CD94/NKG2-A inhibitory complex blocks CD16-triggered Syk and extracellular regulated kinase activation, leading to cytotoxic function of human NK cells. J Immunol 1999; 162:7181-8; PMID:10358164
    • (1999) J Immunol , vol.162 , pp. 7181-7188
    • Palmieri, G.1    Tullio, V.2    Zingoni, A.3    Piccoli, M.4    Frati, L.5    Lopez-Botet, M.6    Santoni, A.7
  • 28
    • 17044400963 scopus 로고    scopus 로고
    • Opposing effect of IFNγ and IFNα on expression of NKG2 receptors: Negative regulation of IFNγ on NK cells
    • 15829421
    • C.Zhang, J.Zhang, R.Sun, J.Feng, H.Wei, Z.Tian. Opposing effect of IFNγ and IFNα on expression of NKG2 receptors:Negative regulation of IFNγ on NK cells. Int Immuno Pharmacol 2005; 5:1057-67; PMID:15829421; http://dx.doi.org/10.1016/j.intimp.2005.02.003
    • (2005) Int Immuno Pharmacol , vol.5 , pp. 1057-1067
    • Zhang, C.1    Zhang, J.2    Sun, R.3    Feng, J.4    Wei, H.5    Tian, Z.6
  • 29
    • 20844438187 scopus 로고    scopus 로고
    • NK-cell reconstitution after haploidentical hematopoietic stem-cell transplantations: immaturity of NK cells and inhibitory effect of NKG2A override GvL effect
    • 15687235
    • S.Nguyen, N.Dhedin, J.-P.Vernant, M.Kuentz, A.A.Jijakli, N.Rouas-Freiss, E.D.Carosella, A.Boudifa, P.Debré, V.Vieillard. NK-cell reconstitution after haploidentical hematopoietic stem-cell transplantations:immaturity of NK cells and inhibitory effect of NKG2A override GvL effect. Blood 2005; 105:4135-42; PMID:15687235; http://dx.doi.org/10.1182/blood-2004-10-4113
    • (2005) Blood , vol.105 , pp. 4135-4142
    • Nguyen, S.1    Dhedin, N.2    Vernant, J.-P.3    Kuentz, M.4    Jijakli, A.A.5    Rouas-Freiss, N.6    Carosella, E.D.7    Boudifa, A.8    Debré, P.9    Vieillard, V.10
  • 30
    • 84939266734 scopus 로고    scopus 로고
    • Molecular properties of human IgG subclasses and their implications for designing therapeutic monoclonal antibodies against infectious diseases
    • 25900877
    • V.Irani, A.J.Guy, D.Andrew, J.G.Beeson, P.A.Ramsland, J.S.Richards. Molecular properties of human IgG subclasses and their implications for designing therapeutic monoclonal antibodies against infectious diseases. Mol Immunol 2015; 67:171-82; PMID:25900877; http://dx.doi.org/10.1016/j.molimm.2015.03.255
    • (2015) Mol Immunol , vol.67 , pp. 171-182
    • Irani, V.1    Guy, A.J.2    Andrew, D.3    Beeson, J.G.4    Ramsland, P.A.5    Richards, J.S.6
  • 31
    • 15844396467 scopus 로고    scopus 로고
    • The role of TCR stimulation and TGF-β in controlling the expression of CD94/NKG2A receptors on CD8 T cells
    • 15714583
    • A.Gunturi, R.E.Berg, E.Crossley, S.Murray, J.Forman. The role of TCR stimulation and TGF-β in controlling the expression of CD94/NKG2A receptors on CD8 T cells. Eur J Immunol 2005; 35:766-75; PMID:15714583; http://dx.doi.org/10.1002/eji.200425735
    • (2005) Eur J Immunol , vol.35 , pp. 766-775
    • Gunturi, A.1    Berg, R.E.2    Crossley, E.3    Murray, S.4    Forman, J.5
  • 32
    • 84941785933 scopus 로고    scopus 로고
    • O3.2Phase I and dose ranging, phase II studies with IPH2201, a humanized monoclonal antibody targeting HLA-E receptor CD94/NKG2A
    • L.Seymour, A.Tinker, H.Hirte, N.Wagtmann, P.Dodion. O3.2Phase I and dose ranging, phase II studies with IPH2201, a humanized monoclonal antibody targeting HLA-E receptor CD94/NKG2A. Annals Oncol 2015; 26:ii3; http://dx.doi.org/10.1093/annonc/mdv081.2
    • (2015) Annals Oncol , vol.26 , pp. ii3
    • Seymour, L.1    Tinker, A.2    Hirte, H.3    Wagtmann, N.4    Dodion, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.