Severe molecular defects exhibited by the R179H mutation in human vascular smooth muscle α-actin

Journal of Biological Chemistry

Volumn 291, Issue 41, 2016, Pages 21729-21739

  Lu, Hailong ^a   Fagnant, Patricia M ^a   Krementsova, Elena B ^a   Trybus, Kathleen M ^a  

^a UNIVERSITY OF VERMONT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINS; DEFECTS; MUSCLE; POLYMERIZATION;

CELLULAR PHENOTYPES; CRITICAL CONCENTRATION; EQUIMOLAR AMOUNT; MOLECULAR DEFECTS; PATIENT PROGNOSIS; POLYMERIZATION RATES; SMOOTH MUSCLE CELLS; VASCULAR SMOOTH MUSCLES;

PROTEINS;

ALPHA SMOOTH MUSCLE ACTIN; COFILIN; METHENAMINE; MYOCARDIN; MYOCARDIN RELATED TRANSCRIPTION FACTOR A; PROFILIN; UNCLASSIFIED DRUG; ACTA2 PROTEIN, HUMAN; ACTA2 PROTEIN, MOUSE; ACTIN; MKL1 PROTEIN, HUMAN; MKL1 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ACTIN FILAMENT; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIMIT OF QUANTITATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN POLYMERIZATION; PROTEIN PROTEIN INTERACTION; VASCULAR SMOOTH MUSCLE CELL; AMINO ACID SUBSTITUTION; ANIMAL; CHEMISTRY; GENETICS; METABOLISM; MISSENSE MUTATION; MOUSE; STRUCTURE ACTIVITY RELATION;

ACTINS; AMINO ACID SUBSTITUTION; ANIMALS; HUMANS; MICE; MUTATION, MISSENSE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATORS;

EID: 84990838666     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.744011     Document Type: Article

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