A periodic pattern of evolutionarily conserved basic and acidic residues constitutes the binding interface of actin-tropomyosin

Journal of Biological Chemistry

Volumn 288, Issue 14, 2013, Pages 9602-9609

  Barua, Bipasha ^a   Fagnant, Patricia M ^b   Winkelmann, Donald A ^a   Trybus, Kathleen M ^b   Hitchcock De Gregori, Sarah E ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF VERMONT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN-BINDING PROTEINS; ATOMIC RESOLUTION STRUCTURES; BINDING INTERFACE; COMPLEX FORMATIONS; COMPUTATIONAL MODELING; FILAMENT STRUCTURE; HYDROPHOBIC INTERACTIONS; PERIODIC PATTERN;

ATOMS; ELECTRON MICROSCOPY; INTERFACE STATES; MUTAGENESIS;

PROTEINS;

ASPARTIC ACID; GLUTAMIC ACID; LYSINE; MYOSIN; SMOOTH MUSCLE ACTIN; TROPOMYOSIN; TROPONIN;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSKELETON; GENETIC CONSERVATION; HYDROPHOBICITY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; STATIC ELECTRICITY; VALIDATION STUDY;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHICKENS; CIRCULAR DICHROISM; CYTOSKELETON; EVOLUTION, MOLECULAR; HUMANS; INSECTS; MICROSCOPY, ELECTRON; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH; MUTATION; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RATS; SEQUENCE ANALYSIS, DNA; STATIC ELECTRICITY; SURFACE PROPERTIES; TROPOMYOSIN;

EID: 84875991378     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.451161     Document Type: Article

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