Neutrophil extracellular traps exacerbate Th1-mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation

European Journal of Immunology

Volumn 46, Issue 11, 2016, Pages 2542-2554

  Papadaki, Garyfalia ^a,b   Kambas, Konstantinos ^c   Choulaki, Christiana ^a,b   Vlachou, Katerina ^a,b,d   Drakos, Elias ^e   Bertsias, George ^a,b   Ritis, Konstantinos ^c   Boumpas, Dimitrios T ^a,d,f,g   Thompson, Paul R ^h   Verginis, Panayotis ^d   Sidiropoulos, Prodromos ^b  

^a INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

^b UNIVERSITY OF CRETE   (Greece)

^c DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^d BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^e UNIVERSITY OF CRETE   (Greece)

^f NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^g UNIVERSITY OF ATHENS   (Greece)

^h UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Autoimmune responses; Cl amidine; Collagen induced arthritis; Neutrophil extracellular traps; Rheumatoid arthritis

Indexed keywords

COLLAGEN ANTIBODY; COLLAGEN TYPE 2; DNA; INTERLEUKIN 17; INTERLEUKIN 6; PROTEIN ARGININE DEIMINASE; COLLAGEN; GAMMA INTERFERON; HYDROLASE; INTERLEUKIN-6, MOUSE; N-ALPHA-BENZOYL-N5-(2-CHLORO-1-IMINOETHYL)-L-ORNITHINE AMIDE; ORNITHINE; PEPTIDYLARGININE DEIMINASE 4, MOUSE;

ADULT; ANIMAL TISSUE; ARTHRITIS; ARTICLE; ATTENUATION; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CELL MATURATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DISEASE ACTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; EXTRACELLULAR TRAP; FEMALE; FLOW CYTOMETRY; HUMAN; IN VITRO STUDY; LYMPH NODE; LYMPHOCYTE PROLIFERATION; MALE; MIDDLE AGED; MOLECULE; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH17 CELL; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; CELL DIFFERENTIATION; DBA MOUSE; DISEASE MODEL; DRUG EFFECTS; EXPERIMENTAL ARTHRITIS; IMMUNOLOGY; METABOLISM; PATHOPHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; AUTOIMMUNITY; CELL DIFFERENTIATION; COLLAGEN; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; EXTRACELLULAR TRAPS; HUMANS; HYDROLASES; INTERFERON-GAMMA; INTERLEUKIN-6; MICE; MICE, INBRED DBA; ORNITHINE; TH1 CELLS;

EID: 84990228550     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201646542     Document Type: Article

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