-
1
-
-
70350382274
-
The detection of environmental mutagens and potential
-
Ames BN (1984) The detection of environmental mutagens and potential. Cancer 53:2030-2040
-
(1984)
Cancer
, vol.53
, pp. 2030-2040
-
-
Ames, B.N.1
-
2
-
-
0002948521
-
Measuring intra-assay agreement for the Ames Salmonella assay
-
Hotorn L (ed), Springer-Verlag, Heidelberg
-
Piegorsch WW, Zeiger E (1991) Measuring intra-assay agreement for the Ames Salmonella assay. In: Hotorn L (ed) Statistical methods in toxicology, Lecture notes in medical informatics, vol 43. Springer-Verlag, Heidelberg, pp 35-41
-
(1991)
Statistical Methods in Toxicology, Lecture Notes in Medical Informatics
, vol.43
, pp. 35-41
-
-
Piegorsch, W.W.1
Zeiger, E.2
-
3
-
-
0022400101
-
Fundamental structural alerts to potential carcinogenicity or noncarcinogenicity
-
Ashby J (1985) Fundamental structural alerts to potential carcinogenicity or noncarcinogenicity. Environ Mutagen 7:919-921
-
(1985)
Environ Mutagen
, vol.7
, pp. 919-921
-
-
Ashby, J.1
-
4
-
-
0023856614
-
Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the US NCI/NTP
-
Ashby J, Tennant RW (1988) Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the US NCI/NTP. Mutat Res 204:17-115
-
(1988)
Mutat Res
, vol.204
, pp. 17-115
-
-
Ashby, J.1
Tennant, R.W.2
-
5
-
-
33746146805
-
Structural alerts of mutagens and carcinogens
-
Benigni R, Bossa C (2006) Structural alerts of mutagens and carcinogens. Curr Comput Aided Drug Des 2:169-176
-
(2006)
Curr Comput Aided Drug Des
, vol.2
, pp. 169-176
-
-
Benigni, R.1
Bossa, C.2
-
6
-
-
40949161450
-
In silico tools for sharing data and knowledge on toxicity and metabolism: Derek for windows, meteor, and vitic
-
Marchant CA, Briggs KA, Long A (2008) In silico tools for sharing data and knowledge on toxicity and metabolism: derek for windows, meteor, and vitic. Toxicol Mech Methods 18:177-187
-
(2008)
Toxicol Mech Methods
, vol.18
, pp. 177-187
-
-
Marchant, C.A.1
Briggs, K.A.2
Long, A.3
-
7
-
-
12144257810
-
Derivation and validation of toxicophores for mutagenicity prediction
-
Kazius J, McGuire R, Bursi R (2005) Derivation and validation of toxicophores for mutagenicity prediction. J Med Chem 48:312-320
-
(2005)
J Med Chem
, vol.48
, pp. 312-320
-
-
Kazius, J.1
McGuire, R.2
Bursi, R.3
-
8
-
-
84892637074
-
Automatic knowledge extraction from chemical structures: The case of mutagenicity prediction
-
Ferrari T, Cattaneo D, Gini G et al (2013) Automatic knowledge extraction from chemical structures: the case of mutagenicity prediction. SAR QSAR Environ Res 24:365-383
-
(2013)
SAR QSAR Environ Res
, vol.24
, pp. 365-383
-
-
Ferrari, T.1
Cattaneo, D.2
Gini, G.3
-
9
-
-
0026778110
-
MULTICASE 1. A hierarchical computer automated structure evaluation program
-
Klopman G (1992) MULTICASE 1. A hierarchical computer automated structure evaluation program. Quant Struct Act Rel 11:76-184
-
(1992)
Quant Struct Act Rel
, vol.11
, pp. 76-184
-
-
Klopman, G.1
-
10
-
-
0028157137
-
Prediction of carcinogenicity/mutagenicity using MULTICASE
-
Klopman G, Rosenkranz HS (1994) Prediction of carcinogenicity/mutagenicity using MULTICASE. Mutation Res 305:33-46
-
(1994)
Mutation Res
, vol.305
, pp. 33-46
-
-
Klopman, G.1
Rosenkranz, H.S.2
-
11
-
-
84908233587
-
Computational derivation of structural alerts from large toxicology data sets
-
Ahlberg E, Carlsson L, Boyer S (2014) Computational derivation of structural alerts from large toxicology data sets. J Chem Inf Model 54:2945-2952
-
(2014)
J Chem Inf Model
, vol.54
, pp. 2945-2952
-
-
Ahlberg, E.1
Carlsson, L.2
Boyer, S.3
-
12
-
-
84990252823
-
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Guidance for industry, genotoxic and carcinogenic impurities in drug substances and products: recommended approaches, Accessed 7 July 2015
-
U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER) (2008) Guidance for industry, genotoxic and carcinogenic impurities in drug substances and products: recommended approaches. http://www.fda.gov/ohrms/ dockets/98fr/fda-2008-d-0629-gdl.pdf. Accessed 7 July 2015
-
(2008)
-
-
-
13
-
-
84990252172
-
-
Accessed 7 July 2015
-
ToxRead. http://www.toxgate.eu. Accessed 7 July 2015
-
Toxread
-
-
-
14
-
-
84919840872
-
ToxRead: A tool to assist in read-across and its use to assess mutagenicity of chemicals
-
Gini G, Franchi AM, Manganaro A et al (2014) ToxRead: a tool to assist in read-across and its use to assess mutagenicity of chemicals. SAR QSAR Environ Res 25:999-1011
-
(2014)
SAR QSAR Environ Res
, vol.25
, pp. 999-1011
-
-
Gini, G.1
Franchi, A.M.2
Manganaro, A.3
-
16
-
-
84978913392
-
-
version 3.3.2, Accessed 7 July 2015
-
OECD (2014) The OECD QSAR toolbox, version 3.3.2. http://www.oecd.org/chemicalsafety/ risk-assessment/theoecdqsartoolbox. htm. Accessed 7 July 2015
-
(2014)
The OECD QSAR Toolbox
-
-
-
17
-
-
84990178437
-
-
AMBIT, Version 2.4.11, Accessed 7 July 2015
-
AMBIT, Version 2.4.11. http://ambit.sourceforge. net/. Accessed 7 July 2015
-
-
-
-
18
-
-
84990220629
-
-
Accessed 7 July 2015
-
Toxmatch—OpenTox. http://www.opentox. org/dev/documentation/components/toxmatch. Accessed 7 July 2015
-
Toxmatch—OpenTox
-
-
-
19
-
-
84990218963
-
-
Accessed 23 July 2015
-
Leadscope. http://www.leadscope.com/. Accessed 23 July 2015
-
Leadscope
-
-
-
21
-
-
84876052492
-
-
Accessed 7 July 2015
-
ChemIDplus. http://chem.sis.nlm.nih.gov/ chemidplus/. Accessed 7 July 2015
-
Chemidplus
-
-
-
22
-
-
84990185873
-
-
Guidance on information requirements and chemical safety assessment, Chapter R.6: QSARs and grouping of chemicals, Accessed 23 July 2015
-
European Chemicals Agency (2008) Guidance on information requirements and chemical safety assessment, Chapter R.6: QSARs and grouping of chemicals. http://echa.europa. eu/documents/10162/13632/information_ requirements_r6_en.pdf/. Accessed 23 July 2015
-
(2008)
-
-
-
23
-
-
84990174267
-
-
Guidance on grouping of chemicals, 2nd ed. Environment Directorate Joint Meeting of the chemicals committee and the working party on chemicals, pesticides and biotechnology, Organization for Economic Co-operation and Development, ENV/JM/ MONO(2014)4, Accessed 7 July 2015
-
OECD (2014) Guidance on grouping of chemicals, 2nd ed. Environment Directorate Joint Meeting of the chemicals committee and the working party on chemicals, pesticides and biotechnology, Organization for Economic Co-operation and Development, ENV/JM/ MONO(2014)4. http://www.oecd.org/offi-cialdocuments/publicdisplaydocumentpdf/?c ote=env/jm/mono%282014%294&doclangu age=en. Accessed 7 July 2015
-
(2014)
-
-
-
24
-
-
84990223853
-
-
The CALEIDOS project: chemical Assessment according to Legislation Enhancing the In silico Documentation and Safe use. Funded by the LIFE+ EC Programme 2013-2015, Accessed 23 July 2015
-
The CALEIDOS project: chemical Assessment according to Legislation Enhancing the In silico Documentation and Safe use. Funded by the LIFE+ EC Programme 2013-2015. http://www.caleidos-life.eu/. Accessed 23 July 2015
-
-
-
-
25
-
-
84990220387
-
-
The PROSIL project: promoting the use of in silico methods in industry. Funded by the LIFE+ EC Programme 2013-2016, Accessed 23 July 2015
-
The PROSIL project: promoting the use of in silico methods in industry. Funded by the LIFE+ EC Programme 2013-2016. http:// www.life-prosil.eu/. Accessed 23 July 2015
-
-
-
-
26
-
-
84990224291
-
-
The ANTARES project: alternative non-testing methods assessed for REACH substances. Funded by the LIFE+ EC Programme 2010-2012, Accessed 7 July 2015
-
The ANTARES project: alternative non-testing methods assessed for REACH substances. Funded by the LIFE+ EC Programme 2010-2012. http://www.antares-life.eu/. Accessed 7 July 2015
-
-
-
-
27
-
-
70349910465
-
Benchmark data set for in silico prediction of Ames mutagenicity
-
Hansen K, Mika S, Schroeter T et al (2009) Benchmark data set for in silico prediction of Ames mutagenicity. J Chem Inf Model 49:2077-2081
-
(2009)
J Chem Inf Model
, vol.49
, pp. 2077-2081
-
-
Hansen, K.1
Mika, S.2
Schroeter, T.3
-
28
-
-
84876103909
-
-
Accessed 7 July 2015
-
Chemical Carcinogenesis Research Information System (2009) NCRI informatics Initiative Homepage. http://www.cancerinformatics. org.uk/matrix/CCRIS.htm. Accessed 7 July 2015
-
(2009)
NCRI Informatics Initiative Homepage
-
-
-
29
-
-
4043167653
-
Data mining and machine learning techniques for the identification of mutagenicity inducing substructures and structure-activity relationships of noncongeneric compounds
-
Helma C, Cramer T, Kramer S, Raedt LD (2004) Data mining and machine learning techniques for the identification of mutagenicity inducing substructures and structure-activity relationships of noncongeneric compounds. J Chem Inf Comput Sci 44:1402-1411
-
(2004)
J Chem Inf Comput Sci
, vol.44
, pp. 1402-1411
-
-
Helma, C.1
Cramer, T.2
Kramer, S.3
Raedt, L.D.4
-
30
-
-
0141890760
-
Predictive toxicology: Benchmarking molecular descriptors and statistical methods
-
Feng J, Lurati L, Ouyang H et al (2003) Predictive toxicology: benchmarking molecular descriptors and statistical methods. J Chem Inf Comput Sci 43:1463-1470
-
(2003)
J Chem Inf Comput Sci
, vol.43
, pp. 1463-1470
-
-
Feng, J.1
Lurati, L.2
Ouyang, H.3
-
31
-
-
23944460899
-
Towards the creation of an international toxicology information centre
-
Judson PN, Cooke PA, Doerrer NG et al (2005) Towards the creation of an international toxicology information centre. Toxicology 213:117-128
-
(2005)
Toxicology
, vol.213
, pp. 117-128
-
-
Judson, P.N.1
Cooke, P.A.2
Doerrer, N.G.3
-
32
-
-
32544452551
-
An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints
-
Matthews EJ, Kruhlak NL, Cimino MC et al (2006) An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints. Regul Toxicol Pharmacol 44:83-96
-
(2006)
Regul Toxicol Pharmacol
, vol.44
, pp. 83-96
-
-
Matthews, E.J.1
Kruhlak, N.L.2
Cimino, M.C.3
-
33
-
-
73749088210
-
Benigni/Bossa rulebase for mutagenicity and carcinogenicity—a module of Toxtree
-
Accessed 19 Jun 2015
-
Benigni R, Bossa C, Jeliazkova N et al (2008) Benigni/Bossa rulebase for mutagenicity and carcinogenicity—a module of Toxtree. JRC Scientific and Technical Reports. https://eurlecvam.jrc.ec.europa.eu/laboratoriesresearch/predictive_toxicology/doc/EUR_23241_EN.pdf.Accessed19Jun2015
-
(2008)
JRC Scientific and Technical Reports
-
-
Benigni, R.1
Bossa, C.2
Jeliazkova, N.3
-
36
-
-
84920366801
-
A generalizable definition of chemical similarity for read-across
-
Floris M, Manganaro A, Nicolotti O et al (2014) A generalizable definition of chemical similarity for read-across. J Cheminform 6:39
-
(2014)
J Cheminform
, vol.6
, pp. 39
-
-
Floris, M.1
Manganaro, A.2
Nicolotti, O.3
-
37
-
-
84990244342
-
Mutagenicity of nitro furan nitroimidazol and nitrothiazole derivatives on salmonella microsome system
-
Byeon WH, Hyun HH, Lee SY (1976) Mutagenicity of nitro furan nitroimidazol and nitrothiazole derivatives on salmonella microsome system. Kor J Microbiol 14:151-158
-
(1976)
Kor J Microbiol
, vol.14
, pp. 151-158
-
-
Byeon, W.H.1
Hyun, H.H.2
Lee, S.Y.3
-
38
-
-
84885838418
-
-
Accessed 7 July 2015
-
ChemSpider. http://www.chemspider.com/. Accessed 7 July 2015
-
Chemspider
-
-
-
40
-
-
84990204465
-
-
Marvin, intuitive applications and API for chemical sketching, visualization and data exploration, Accessed 19 Jun 2015
-
Marvin, intuitive applications and API for chemical sketching, visualization and data exploration. http://www.chemaxon.com/ products/marvin/. Accessed 19 Jun 2015
-
-
-
-
41
-
-
84990235875
-
-
Accessed 7 July 2015
-
Kode from data to knowledge. http://www. kode-solutions.net. Accessed 7 July 2015
-
Kode from Data to Knowledge
-
-
|