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Volumn 54, Issue 3, 2016, Pages 1207-1217

Extracellular Vesicles Containing P301L Mutant Tau Accelerate Pathological Tau Phosphorylation and Oligomer Formation but Do Not Seed Mature Neurofibrillary Tangles in ALZ17 Mice

Author keywords

Alzheimer's disease; extracellular vesicles; phosphorylation; seeding; tau

Indexed keywords

MUTANT PROTEIN; OLIGOMER; TAU PROTEIN; MAPT PROTEIN, HUMAN;

EID: 84990041211     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-160371     Document Type: Article
Times cited : (75)

References (27)
  • 1
    • 33749150163 scopus 로고    scopus 로고
    • Staging of Alzheimer diseaseassociated neurofibrillary pathology using paraffin sections and immunocytochemistry
    • Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K (2006) Staging of Alzheimer diseaseassociated neurofibrillary pathology using paraffin sections and immunocytochemistry. acta Neuropathol 112, 389-404.
    • (2006) Acta Neuropathol , vol.112 , pp. 389-404
    • Braak, H.1    Alafuzoff, I.2    Arzberger, T.3    Kretzschmar, H.4    Del Tredici, K.5
  • 4
    • 77249133010 scopus 로고    scopus 로고
    • Prion-like mechanisms in neurodegenerative diseases
    • Frost B, Diamond MI (2010) Prion-like mechanisms in neurodegenerative diseases. Nat Rev Neurosci 11, 155-159.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 155-159
    • Frost, B.1    Diamond, M.I.2
  • 9
    • 84939569230 scopus 로고    scopus 로고
    • Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections
    • Iba M, McBride JD, Guo JL, Zhang B, Trojanowski JQ, Lee VM (2015) Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections. acta Neuropathol 130, 349-362.
    • (2015) Acta Neuropathol , vol.130 , pp. 349-362
    • Iba, M.1    McBride, J.D.2    Guo, J.L.3    Zhang, B.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 10
    • 84872346089 scopus 로고    scopus 로고
    • Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mousemodel of Alzheimer's-like tauopathy
    • Iba M, Guo JL, McBride JD, Zhang B, Trojanowski JQ, Lee VM (2013) Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mousemodel of Alzheimer's-like tauopathy. J Neurosci 33, 1024-1037.
    • (2013) J Neurosci , vol.33 , pp. 1024-1037
    • Iba, M.1    Guo, J.L.2    McBride, J.D.3    Zhang, B.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 11
    • 77956404647 scopus 로고    scopus 로고
    • Exosomes: Extracellular organelles important in intercellular communication
    • Mathivanan S, Ji H, Simpson RJ (2010) Exosomes: Extracellular organelles important in intercellular communication. J Proteomics 73, 1907-1920.
    • (2010) J Proteomics , vol.73 , pp. 1907-1920
    • Mathivanan, S.1    Ji, H.2    Simpson, R.J.3
  • 14
  • 16
    • 84879232559 scopus 로고    scopus 로고
    • Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission
    • Mohamed NV, Herrou T, Plouffe V, Piperno N, Leclerc N (2013) Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission. Eur J Neurosci 37, 1939-1948.
    • (2013) Eur J Neurosci , vol.37 , pp. 1939-1948
    • Mohamed, N.V.1    Herrou, T.2    Plouffe, V.3    Piperno, N.4    Leclerc, N.5
  • 17
    • 84893488880 scopus 로고    scopus 로고
    • Tangles, Toxicity, and tau secretion inAD-newapproaches to a vexing problem
    • Gendreau KL, Hall GF (2013) Tangles, Toxicity, and tau secretion inAD-newapproaches to a vexing problem. Front Neurol 4, 160.
    • (2013) Front Neurol , vol.4 , pp. 160
    • Gendreau, K.L.1    Hall, G.F.2
  • 18
    • 84871118236 scopus 로고    scopus 로고
    • The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space
    • Perez-Gonzalez R, Gauthier SA, Kumar A, Levy E (2012) The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space. J Biol Chem 287, 43108-43115.
    • (2012) J Biol Chem , vol.287 , pp. 43108-43115
    • Perez-Gonzalez, R.1    Gauthier, S.A.2    Kumar, A.3    Levy, E.4
  • 19
    • 84974530686 scopus 로고    scopus 로고
    • Extracellular vesicles isolated from brains of rTg4510 mice seed tau aggregation in a threshold-dependent manner
    • Polanco JC, Scicluna BJ, Hill AF, Götz J (2016) Extracellular vesicles isolated from brains of rTg4510 mice seed tau aggregation in a threshold-dependent manner. J Biol Chem 291, 12445-12466.
    • (2016) J Biol Chem , vol.291 , pp. 12445-12466
    • Polanco, J.C.1    Scicluna, B.J.2    Hill, A.F.3    Götz, J.4
  • 22
    • 84956641751 scopus 로고    scopus 로고
    • Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia
    • Van der Jeugd A, Vermaercke B, Halliday GM, Staufenbiel M, Götz J (2016) Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia. Neurobiol Learn Mem 130, 34-43.
    • (2016) Neurobiol Learn Mem , vol.130 , pp. 34-43
    • Van Der Jeugd, A.1    Vermaercke, B.2    Halliday, G.M.3    Staufenbiel, M.4    Götz, J.5
  • 23
    • 85014396442 scopus 로고    scopus 로고
    • A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions
    • Baker S, Götz J (2016) A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions. acta Neuropathol Commun 4, 32.
    • (2016) Acta Neuropathol Commun , vol.4 , pp. 32
    • Baker, S.1    Götz, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.